DK0524143T3 - Fremgangsmåde til fremstilling af aktiverede sialinsyrer - Google Patents

Fremgangsmåde til fremstilling af aktiverede sialinsyrer

Info

Publication number: DK0524143T3
Authority: DK; Denmark
Prior art keywords: preparation; cytidine; sialic acids; activated sialic; acids
Prior art date: 1991-07-17

Application number

DK92810522T

Other languages

Danish (da)

English (en)

Inventor

Christian Wandrey

Matthias Kittelmann

Oreste Ghisalba

Teresa Klein

Udo Kragl

Original Assignee

Novartis Ag

Forschungszentrum Juelich Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-17

Filing date

1992-07-08

Publication date

1998-08-24

1992-07-08 Application filed by Novartis Ag, Forschungszentrum Juelich Gmbh filed Critical Novartis Ag

1998-08-24 Application granted granted Critical

1998-08-24 Publication of DK0524143T3 publication Critical patent/DK0524143T3/da

Links

238000000034 method Methods 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
125000005629 sialic acid group Chemical group 0.000 title 1
PCDQPRRSZKQHHS-UHFFFAOYSA-N Cytidine 5'-triphosphate Natural products O=C1N=C(N)C=CN1C1C(O)C(O)C(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1 PCDQPRRSZKQHHS-UHFFFAOYSA-N 0.000 abstract 1
102000003960 Ligases Human genes 0.000 abstract 1
108090000364 Ligases Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 abstract 1
PCDQPRRSZKQHHS-ZAKLUEHWSA-N cytidine-5'-triphosphate Chemical compound O=C1N=C(N)C=CN1[C@H]1[C@H](O)[C@@H](O)[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)O1 PCDQPRRSZKQHHS-ZAKLUEHWSA-N 0.000 abstract 1
244000005700 microbiome Species 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/305—Pyrimidine nucleotides

Landscapes

Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK92810522T 1991-07-17 1992-07-08 Fremgangsmåde til fremstilling af aktiverede sialinsyrer DK0524143T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH211991		1991-07-17

Publications (1)

Publication Number	Publication Date
DK0524143T3 true DK0524143T3 (da)	1998-08-24

Family

ID=4226318

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92810522T DK0524143T3 (da)	1991-07-17	1992-07-08	Fremgangsmåde til fremstilling af aktiverede sialinsyrer

Country Status (16)

Country	Link
US (1)	US5334514A (cs)
EP (1)	EP0524143B1 (cs)
JP (1)	JPH05276973A (cs)
KR (1)	KR930002516A (cs)
AT (1)	ATE161051T1 (cs)
AU (1)	AU664036B2 (cs)
CA (1)	CA2073954A1 (cs)
DE (1)	DE59209053D1 (cs)
DK (1)	DK0524143T3 (cs)
ES (1)	ES2110481T3 (cs)
GR (1)	GR3025800T3 (cs)
IE (1)	IE922318A1 (cs)
IL (1)	IL102527A (cs)
MX (1)	MX9204130A (cs)
SG (1)	SG49879A1 (cs)
TW (1)	TW287200B (cs)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4431280A1 (de) *	1994-09-02	1996-03-07	Hoechst Ag	Verfahren zur Isolierung und Reinigung von nukleotidaktivierten Zuckern aus biologischen Quellen
US5585211A (en) *	1995-02-06	1996-12-17	Firstein; Leon A.	Fabrication and use of sub-micron dimensional standard
JPWO2004009830A1 (ja)	2002-07-18	2005-11-17	ヤマサ醤油株式会社	Ｃｍｐ−ｎ−アセチルノイラミン酸の製造法
US8450088B2 (en)	2003-09-26	2013-05-28	Yamasa Corporation	Process for producing CMP-N-acetylneuraminic acid
US9783838B2 (en) *	2011-11-07	2017-10-10	The Regents Of The University Of California	PmST3 enzyme for chemoenzymatic synthesis of alpha-2-3-sialosides
ES2759503T3 (es)	2013-05-02	2020-05-11	Glykos Finland Oy	Conjugados de una glicoproteína o un glicano con una carga útil tóxica
EP2905341B1 (en) *	2014-02-07	2020-04-29	Jennewein Biotechnologie GmbH	Methods for producing GDP-fucose using nucleotide sugar transporters and recombinant microorganism host cells used therefor
CN119912505A (zh) *	2025-04-02	2025-05-02	浙江熙正霖生物科技有限公司	一种从发酵液中提纯唾液酸的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0263533A3 (en) *	1983-03-01	1990-05-30	C.R.C. Compagnia di Ricerca Chimica S.p.A.	A method for preparing the cytidine monophosphate of 5-acetamido-3,5-dideoxy-d-glycero-d-galactononulosaminic acid
DE3626915A1 (de) *	1986-08-08	1988-02-11	Hoechst Ag	Verfahren zur enzymatischen synthese eines n-acetylneuraminsaeure-haltigen trisaccharids
JPH02177891A (ja) *	1988-12-28	1990-07-10	Snow Brand Milk Prod Co Ltd	複合酵素反応によるシチジン‐５′‐モノホスフオシアル酸の合成方法
DE3937891A1 (de) *	1989-11-15	1991-05-16	Forschungszentrum Juelich Gmbh	Enzymatisches verfahren zur herstellung von n-acetylneuraminsaeure

1992
- 1992-07-08 EP EP92810522A patent/EP0524143B1/de not_active Expired - Lifetime
- 1992-07-08 SG SG9608076A patent/SG49879A1/en unknown
- 1992-07-08 ES ES92810522T patent/ES2110481T3/es not_active Expired - Lifetime
- 1992-07-08 DK DK92810522T patent/DK0524143T3/da active
- 1992-07-08 DE DE59209053T patent/DE59209053D1/de not_active Expired - Fee Related
- 1992-07-08 AT AT92810522T patent/ATE161051T1/de not_active IP Right Cessation
- 1992-07-15 MX MX9204130A patent/MX9204130A/es not_active IP Right Cessation
- 1992-07-15 KR KR1019920012561A patent/KR930002516A/ko not_active Ceased
- 1992-07-15 CA CA002073954A patent/CA2073954A1/en not_active Abandoned
- 1992-07-16 AU AU20348/92A patent/AU664036B2/en not_active Ceased
- 1992-07-16 IE IE231892A patent/IE922318A1/en not_active Application Discontinuation
- 1992-07-16 JP JP4189647A patent/JPH05276973A/ja active Pending
- 1992-07-16 IL IL10252792A patent/IL102527A/en not_active IP Right Cessation
- 1992-07-18 TW TW081105712A patent/TW287200B/zh active
1993
- 1993-11-12 US US08/152,269 patent/US5334514A/en not_active Expired - Fee Related
1997
- 1997-12-30 GR GR970403446T patent/GR3025800T3/el unknown

Also Published As

Publication number	Publication date
SG49879A1 (en)	2001-03-20
AU2034892A (en)	1993-01-21
IE922318A1 (en)	1993-01-27
GR3025800T3 (en)	1998-03-31
EP0524143B1 (de)	1997-12-10
JPH05276973A (ja)	1993-10-26
DE59209053D1 (de)	1998-01-22
CA2073954A1 (en)	1993-01-18
ATE161051T1 (de)	1997-12-15
US5334514A (en)	1994-08-02
IL102527A0 (en)	1993-01-14
ES2110481T3 (es)	1998-02-16
EP0524143A1 (de)	1993-01-20
AU664036B2 (en)	1995-11-02
TW287200B (cs)	1996-10-01
MX9204130A (es)	1993-07-01
KR930002516A (ko)	1993-02-23
IL102527A (en)	1996-08-04

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