DK0532530T3 - Derivater af 6-amino-octahydroindolizintriol - Google Patents

Derivater af 6-amino-octahydroindolizintriol

Info

Publication number: DK0532530T3
Authority: DK; Denmark
Prior art keywords: amino; derivatives; octahydroindolizine; triol; compounds
Prior art date: 1990-06-04

Application number

DK91909495.3T

Other languages

Danish (da)

English (en)

Inventor

Paul S Liu

Mohinder S Kang

Original Assignee

Merrell Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-04

Filing date

1991-05-08

Publication date

1997-08-25

1991-05-08 Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc

1997-08-25 Application granted granted Critical

1997-08-25 Publication of DK0532530T3 publication Critical patent/DK0532530T3/da

Links

KOMQIBDSYRYZJX-UHFFFAOYSA-N C1C(N)CCC2C(O)C(O)C(O)N21 Chemical class C1C(N)CCC2C(O)C(O)C(O)N21 KOMQIBDSYRYZJX-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
JDVVGAQPNNXQDW-WCMLQCRESA-N Castanospermine Natural products O[C@H]1[C@@H](O)[C@H]2[C@@H](O)CCN2C[C@H]1O JDVVGAQPNNXQDW-WCMLQCRESA-N 0.000 abstract 1
JDVVGAQPNNXQDW-TVNFTVLESA-N Castinospermine Chemical compound C1[C@H](O)[C@@H](O)[C@H](O)[C@H]2[C@@H](O)CCN21 JDVVGAQPNNXQDW-TVNFTVLESA-N 0.000 abstract 1
102000002268 Hexosaminidases Human genes 0.000 abstract 1
108010000540 Hexosaminidases Proteins 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
-1 ester derivatives of 6-amino-octahydro-1,7,8-indolizinetriol Chemical class 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Cosmetics (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Peptides Or Proteins (AREA)

DK91909495.3T 1990-06-04 1991-05-08 Derivater af 6-amino-octahydroindolizintriol DK0532530T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/532,522 US5079254A (en)	1990-06-04	1990-06-04	Derivatives of 6-aminooctahydroindolizinetriol

Publications (1)

Publication Number	Publication Date
DK0532530T3 true DK0532530T3 (da)	1997-08-25

Family

ID=24122149

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91909495.3T DK0532530T3 (da)	1990-06-04	1991-05-08	Derivater af 6-amino-octahydroindolizintriol

Country Status (15)

Country	Link
US (1)	US5079254A (fr)
EP (1)	EP0532530B1 (fr)
JP (1)	JP3019265B2 (fr)
KR (1)	KR100195421B1 (fr)
AT (1)	ATE155685T1 (fr)
AU (1)	AU641771B2 (fr)
CA (1)	CA2082820C (fr)
DE (1)	DE69126978T2 (fr)
DK (1)	DK0532530T3 (fr)
ES (1)	ES2106080T3 (fr)
FI (1)	FI97226C (fr)
GR (1)	GR3025044T3 (fr)
HU (1)	HU212579B (fr)
NO (1)	NO300686B1 (fr)
WO (1)	WO1991018598A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1995013538A1 (fr) *	1993-11-12	1995-05-18	Operon Technologies, Inc.	Procede d'obtention et de criblage de bibliotheques de composes chimiques complexes
WO1995019359A1 (fr) *	1994-01-12	1995-07-20	Massachusetts Institute Of Technology	Procede de production de composes a base de xanthene ou de cubane et inhibitors de protease
US20070066543A1 (en) *	2003-05-22	2007-03-22	The Hospital For Sick Children	Treatment of tay sachs or sandhoff diseases by enhancing hexosaminidase activity
WO2005072268A2 (fr) *	2004-01-20	2005-08-11	Optimer Pharmaceuticals, Inc.	Traitement des pathologies cartilagineuses degeneratives chez les mammiferes au moyen d'inhibiteurs de la glycosidase
KR100858512B1 (ko)	2007-03-29	2008-09-12	포항공과대학교 산학협력단	헥소스아미니데이즈 활성 저해 방법
CA2732335A1 (fr)	2008-08-01	2010-02-04	Simon Fraser University	Inhibiteurs selectifs des glycosidases et leurs utilisations
RU2609210C2 (ru)	2010-12-23	2017-01-31	Алектос Терапьютикс Инк.	Селективные ингибиторы гликозидазы и их применение
EP2691407B1 (fr)	2011-03-31	2017-02-22	Alectos Therapeutics Inc.	Inhibiteurs sélectifs de glycosidases et leurs utilisations
US9701693B2 (en)	2011-06-27	2017-07-11	Alectos Therapeutics Inc.	Selective glycosidase inhibitors and uses thereof
EP2890676B1 (fr)	2012-08-31	2018-12-05	Alectos Therapeutics Inc.	Inhibiteurs de glycosidases et leurs utilisations
EP2890675A4 (fr)	2012-08-31	2016-01-13	Alectos Therapeutics Inc	Inhibiteurs des glycosidases et leurs utilisations
KR20150079711A (ko)	2012-10-31	2015-07-08	알렉토스 테라퓨틱스 인크.	글리코시다아제 저해제 및 이의 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5973519A (ja) *	1982-09-17	1984-04-25	Fujisawa Pharmaceut Co Ltd	スワインソニンの製造法およびそれを含む免疫調整剤
GB8429810D0 (en) *	1984-11-26	1985-01-03	Fujisawa Pharmaceutical Co	Indolizidine derivatives
JPS61277685A (ja) *	1985-05-31	1986-12-08	Fujisawa Pharmaceut Co Ltd	新規インドリジジン誘導体、その製造法およびそれを含有する組成物
DE3620645A1 (de) *	1985-12-20	1987-07-02	Bayer Ag	3-amino-4,5-dihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung
CA1315276C (fr) *	1987-07-02	1993-03-30	Paul S. Liu	Esters et glucosides de castanospermine
JPH01129182A (ja) *	1987-11-16	1989-05-22	Tokyo Keiki Co Ltd	波動伝搬時間測定装置
JPH01277685A (ja) *	1988-04-28	1989-11-08	Hitachi Ltd	ピストンポンプ

1990
- 1990-06-04 US US07/532,522 patent/US5079254A/en not_active Expired - Lifetime
1991
- 1991-05-08 WO PCT/US1991/003179 patent/WO1991018598A1/fr not_active Ceased
- 1991-05-08 HU HU9203829A patent/HU212579B/hu not_active IP Right Cessation
- 1991-05-08 DE DE69126978T patent/DE69126978T2/de not_active Expired - Lifetime
- 1991-05-08 ES ES91909495T patent/ES2106080T3/es not_active Expired - Lifetime
- 1991-05-08 AT AT91909495T patent/ATE155685T1/de not_active IP Right Cessation
- 1991-05-08 EP EP91909495A patent/EP0532530B1/fr not_active Expired - Lifetime
- 1991-05-08 JP JP3509415A patent/JP3019265B2/ja not_active Expired - Lifetime
- 1991-05-08 CA CA002082820A patent/CA2082820C/fr not_active Expired - Lifetime
- 1991-05-08 DK DK91909495.3T patent/DK0532530T3/da active
- 1991-05-08 KR KR1019920703085A patent/KR100195421B1/ko not_active Expired - Fee Related
- 1991-05-08 AU AU78743/91A patent/AU641771B2/en not_active Ceased
1992
- 1992-11-19 FI FI925260A patent/FI97226C/fi not_active IP Right Cessation
- 1992-12-03 NO NO924670A patent/NO300686B1/no not_active IP Right Cessation
1997
- 1997-10-15 GR GR970402690T patent/GR3025044T3/el unknown

Also Published As

Publication number	Publication date
AU641771B2 (en)	1993-09-30
NO924670D0 (no)	1992-12-03
NO924670L (no)	1992-12-03
ATE155685T1 (de)	1997-08-15
HU212579B (en)	1996-08-29
FI97226B (fi)	1996-07-31
FI925260L (fi)	1992-11-19
CA2082820A1 (fr)	1991-12-05
HU9203829D0 (en)	1993-03-29
WO1991018598A1 (fr)	1991-12-12
AU7874391A (en)	1991-12-31
KR930700502A (ko)	1993-03-15
US5079254A (en)	1992-01-07
CA2082820C (fr)	2002-01-22
JPH05507474A (ja)	1993-10-28
FI925260A0 (fi)	1992-11-19
FI97226C (fi)	1996-11-11
DE69126978D1 (de)	1997-08-28
EP0532530B1 (fr)	1997-07-23
GR3025044T3 (en)	1998-01-30
HUT62585A (en)	1993-05-28
EP0532530A4 (en)	1993-05-26
JP3019265B2 (ja)	2000-03-13
EP0532530A1 (fr)	1993-03-24
NO300686B1 (no)	1997-07-07
DE69126978T2 (de)	1997-11-27
KR100195421B1 (ko)	1999-06-15
ES2106080T3 (es)	1997-11-01

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