DK0535192T3 - Hidtil ukendte DNA-gyraseinhibitorer, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende dem - Google Patents
Hidtil ukendte DNA-gyraseinhibitorer, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende demInfo
- Publication number
- DK0535192T3 DK0535192T3 DK92908147.9T DK92908147T DK0535192T3 DK 0535192 T3 DK0535192 T3 DK 0535192T3 DK 92908147 T DK92908147 T DK 92908147T DK 0535192 T3 DK0535192 T3 DK 0535192T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- methods
- dna gyrase
- pharmaceutical preparations
- preparations containing
- Prior art date
Links
- 239000002271 gyrase inhibitor Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
- C07D291/08—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91106105 | 1991-04-17 | ||
| PCT/EP1992/000809 WO1992018490A1 (en) | 1991-04-17 | 1992-04-09 | Novel dna gyrase inhibitors, process for their manufacture and pharmaceutical preparations containing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0535192T3 true DK0535192T3 (da) | 1996-08-05 |
Family
ID=8206629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92908147.9T DK0535192T3 (da) | 1991-04-17 | 1992-04-09 | Hidtil ukendte DNA-gyraseinhibitorer, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende dem |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US5294609A (de) |
| EP (1) | EP0535192B1 (de) |
| JP (1) | JPH05508167A (de) |
| AT (1) | ATE139532T1 (de) |
| DE (1) | DE69211637T2 (de) |
| DK (1) | DK0535192T3 (de) |
| WO (1) | WO1992018490A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0535192T3 (da) * | 1991-04-17 | 1996-08-05 | Hoffmann La Roche | Hidtil ukendte DNA-gyraseinhibitorer, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende dem |
| TW343965B (en) * | 1994-03-30 | 1998-11-01 | Hoffmann La Roche | Novel mono- and bicyclic DNA gyrase inhibitors |
| US7291673B2 (en) * | 2000-06-02 | 2007-11-06 | Eidgenossiche Technische Hochschule Zurich | Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds |
| MXPA05000962A (es) | 2002-07-29 | 2005-05-16 | Hoffmann La Roche | Nuevos benzodioxoles. |
| GB0325830D0 (en) | 2003-11-05 | 2003-12-10 | Novartis Ag | Organic compounds |
| GB0500683D0 (en) | 2005-01-13 | 2005-02-23 | Novartis Ag | Organic compounds |
| CN101326170A (zh) * | 2005-12-14 | 2008-12-17 | 云南省玉溪市维和制药有限公 | 具有抗菌和抗肿瘤活性的新大环内酯化合物 |
| CN104870578B (zh) | 2012-12-28 | 2021-01-12 | 印制能源技术有限公司 | 导电墨水及其制造方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3239350A (en) * | 1965-02-15 | 1966-03-08 | Commercial Solvents Corp | Estrogenic compounds and animal growth promoters |
| US3678159A (en) * | 1966-03-28 | 1972-07-18 | Meiji Seika Kaisha | Antibiotics obtained from streptomyces miharaensis |
| US4175007A (en) * | 1976-10-29 | 1979-11-20 | Merck & Co., Inc. | Process for producing antibiotic A21A |
| JPS594120B2 (ja) * | 1979-06-15 | 1984-01-27 | 大塚製薬株式会社 | 抗生物質セフアマイシンcの製造法 |
| US4534970A (en) * | 1983-06-23 | 1985-08-13 | American Cyanamid Company | Antibacterial antibiotics LL-CO8078α1, α2, α3 and β |
| DK0535192T3 (da) * | 1991-04-17 | 1996-08-05 | Hoffmann La Roche | Hidtil ukendte DNA-gyraseinhibitorer, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende dem |
| US5266484A (en) * | 1991-10-16 | 1993-11-30 | Shin-Etsu Bio, Inc. | Streptomyces spectabilis strains employed for producing streptovaricin C |
-
1992
- 1992-04-09 DK DK92908147.9T patent/DK0535192T3/da active
- 1992-04-09 AT AT92908147T patent/ATE139532T1/de not_active IP Right Cessation
- 1992-04-09 JP JP92507648A patent/JPH05508167A/ja active Pending
- 1992-04-09 EP EP92908147A patent/EP0535192B1/de not_active Expired - Lifetime
- 1992-04-09 US US07/952,537 patent/US5294609A/en not_active Expired - Fee Related
- 1992-04-09 WO PCT/EP1992/000809 patent/WO1992018490A1/en not_active Ceased
- 1992-04-09 DE DE69211637T patent/DE69211637T2/de not_active Expired - Fee Related
-
1994
- 1994-01-06 US US08/177,483 patent/US5399741A/en not_active Expired - Fee Related
- 1994-11-14 US US08/339,442 patent/US5486466A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5294609A (en) | 1994-03-15 |
| DE69211637D1 (de) | 1996-07-25 |
| DE69211637T2 (de) | 1997-01-30 |
| EP0535192B1 (de) | 1996-06-19 |
| EP0535192A1 (de) | 1993-04-07 |
| JPH05508167A (ja) | 1993-11-18 |
| US5399741A (en) | 1995-03-21 |
| ATE139532T1 (de) | 1996-07-15 |
| WO1992018490A1 (en) | 1992-10-29 |
| US5486466A (en) | 1996-01-23 |
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