DK0542807T3 - Anvendelse af 2-phenyl-1,2-benzisoselenazol-3(2H)-on - Google Patents

Anvendelse af 2-phenyl-1,2-benzisoselenazol-3(2H)-on

Info

Publication number: DK0542807T3
Authority: DK; Denmark
Prior art keywords: benzisoselenazol; phenyl; ebselen; cisplatin; reducing
Prior art date: 1990-08-06

Application number

DK91914052T

Other languages

English (en)

Inventor

Glenn S Baldew

N P E Vermeulen

Original Assignee

Rhone Poulenc Rorer Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-06

Filing date

1991-07-31

Publication date

1999-06-21

1991-07-31 Application filed by Rhone Poulenc Rorer Gmbh filed Critical Rhone Poulenc Rorer Gmbh

1999-06-21 Application granted granted Critical

1999-06-21 Publication of DK0542807T3 publication Critical patent/DK0542807T3/da

Links

DYEFUKCXAQOFHX-UHFFFAOYSA-N Ebselen Chemical compound [se]1C2=CC=CC=C2C(=O)N1C1=CC=CC=C1 DYEFUKCXAQOFHX-UHFFFAOYSA-N 0.000 title abstract 3
206010029350 Neurotoxicity Diseases 0.000 abstract 1
206010044221 Toxic encephalopathy Diseases 0.000 abstract 1
DQLATGHUWYMOKM-UHFFFAOYSA-L cisplatin Chemical compound N[Pt](N)(Cl)Cl DQLATGHUWYMOKM-UHFFFAOYSA-L 0.000 abstract 1
229960004316 cisplatin Drugs 0.000 abstract 1
239000000824 cytostatic agent Substances 0.000 abstract 1
230000001085 cytostatic effect Effects 0.000 abstract 1
229950010033 ebselen Drugs 0.000 abstract 1
231100000268 induced nephrotoxicity Toxicity 0.000 abstract 1
230000007135 neurotoxicity Effects 0.000 abstract 1
231100000228 neurotoxicity Toxicity 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Inorganic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK91914052T 1990-08-06 1991-07-31 Anvendelse af 2-phenyl-1,2-benzisoselenazol-3(2H)-on DK0542807T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4024885A DE4024885C2 (de)	1990-08-06	1990-08-06	Verwendung von 2-Phenyl-1,2-benzisoselenazol-3(2H)-on
PCT/EP1991/001438 WO1992002221A1 (en)	1990-08-06	1991-07-31	Use of 2-phenyl-1,2-benzisoselenazol-3(2h)-one

Publications (1)

Publication Number	Publication Date
DK0542807T3 true DK0542807T3 (da)	1999-06-21

Family

ID=6411708

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91914052T DK0542807T3 (da)	1990-08-06	1991-07-31	Anvendelse af 2-phenyl-1,2-benzisoselenazol-3(2H)-on

Country Status (8)

Country	Link
EP (1)	EP0542807B1 (da)
JP (1)	JP3084062B2 (da)
AT (1)	ATE171621T1 (da)
CA (1)	CA2088760C (da)
DE (2)	DE4024885C2 (da)
DK (1)	DK0542807T3 (da)
ES (1)	ES2123510T3 (da)
WO (1)	WO1992002221A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2553434B2 (ja) *	1992-04-28	1996-11-13	第一製薬株式会社	粒状製剤
ES2145065T3 (es)	1993-10-27	2000-07-01	Daiichi Seiyaku Co	Preparacion granular.
ES2177849T3 (es) *	1996-08-27	2002-12-16	Nattermann A & Cie	Preparado farmaceutico, que contiene 2-fenil-1,2-benzoisoselenazol-3(2h)-ona, para el tratamiento de la enfermedad de alzheimer.
DE19825746A1 (de)	1998-06-09	1999-12-16	Biosyn Arzneimittel Gmbh	Kombination von Selen-haltigen Verbindungen mit Zytostatika
CN1166651C (zh) *	2001-06-08	2004-09-15	北京大学药学院	具有抗炎和抗肿瘤作用r-双或糖苯丙异硒唑取代化合物
PL370867A1 (en) *	2001-09-24	2005-05-30	Tosk, Inc.	Reduced toxicity cisplatin formulations and methods for using the same
EP1461033B1 (en)	2001-11-29	2013-02-27	Sound Pharmaceuticals Incorporated	Methods and compositions for ameliorating the undesirable effects of chemotherapy
US6815434B2 (en)	2002-01-04	2004-11-09	Sound Pharmaceuticals Incorporated	Methods for treating hearing loss
KR20070113262A (ko) *	2005-03-08	2007-11-28	사운드 파마슈티칼스 인코퍼레이티드	암의 치료 방법 및 암 치료용 조성물
GB201102248D0 (en)	2011-02-09	2011-03-23	Isis Innovation	Treatment of bipolar disorder

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3027073C2 (de) *	1980-07-17	1985-03-07	A. Nattermann & Cie GmbH, 5000 Köln	Pharmazeutische Präparate, enthaltend 2-Phenyl-1,2-benzisoselenazol-3(2H)-on
DE3616923A1 (de) *	1986-05-20	1987-11-26	Nattermann A & Cie	Neue pharmazeutische verwendung von 2-phenyl-1,2-benzisoselenazol-3(2h)-on
DE3638124C2 (de) *	1986-11-08	1996-09-05	Nattermann A & Cie	Neue pharmazeutische Verwendung von Ebselen
DE3821392A1 (de) *	1988-06-24	1989-12-28	Nattermann A & Cie	Neue pharmazeutische verwendung von 2-phenyl-1,2-benzisoselenazol-3(2h)-on (ebselen)

1990
- 1990-08-06 DE DE4024885A patent/DE4024885C2/de not_active Expired - Lifetime
1991
- 1991-07-31 ES ES91914052T patent/ES2123510T3/es not_active Expired - Lifetime
- 1991-07-31 DK DK91914052T patent/DK0542807T3/da active
- 1991-07-31 AT AT91914052T patent/ATE171621T1/de not_active IP Right Cessation
- 1991-07-31 JP JP03512768A patent/JP3084062B2/ja not_active Expired - Lifetime
- 1991-07-31 DE DE69130292T patent/DE69130292T2/de not_active Expired - Lifetime
- 1991-07-31 WO PCT/EP1991/001438 patent/WO1992002221A1/en not_active Ceased
- 1991-07-31 EP EP91914052A patent/EP0542807B1/en not_active Expired - Lifetime
- 1991-07-31 CA CA002088760A patent/CA2088760C/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CA2088760C (en)	2002-05-07
JP3084062B2 (ja)	2000-09-04
JPH05509309A (ja)	1993-12-22
ES2123510T3 (es)	1999-01-16
EP0542807B1 (en)	1998-09-30
DE69130292T2 (de)	1999-04-08
DE4024885A1 (de)	1992-02-13
DE69130292D1 (de)	1998-11-05
ATE171621T1 (de)	1998-10-15
WO1992002221A1 (en)	1992-02-20
DE4024885C2 (de)	2002-07-18
CA2088760A1 (en)	1993-02-01
EP0542807A1 (en)	1993-05-26

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