DK0565590T3 - Adhesin-oligosaccharid-konjugatvaccine mod Haemophilus influenzae - Google Patents

Adhesin-oligosaccharid-konjugatvaccine mod Haemophilus influenzae

Info

Publication number
DK0565590T3
DK0565590T3 DK92902826T DK92902826T DK0565590T3 DK 0565590 T3 DK0565590 T3 DK 0565590T3 DK 92902826 T DK92902826 T DK 92902826T DK 92902826 T DK92902826 T DK 92902826T DK 0565590 T3 DK0565590 T3 DK 0565590T3
Authority
DK
Denmark
Prior art keywords
influenzae
adhesin
prp
haemophilus influenzae
vaccine against
Prior art date
Application number
DK92902826T
Other languages
Danish (da)
English (en)
Inventor
Howard C Krivan
James E Samuel
Nils Thomas Norberg
Original Assignee
Antex Biolog Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antex Biolog Inc filed Critical Antex Biolog Inc
Application granted granted Critical
Publication of DK0565590T3 publication Critical patent/DK0565590T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/08—Polyoxyalkylene derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
DK92902826T 1990-12-21 1991-12-20 Adhesin-oligosaccharid-konjugatvaccine mod Haemophilus influenzae DK0565590T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63169890A 1990-12-21 1990-12-21
PCT/US1991/009693 WO1992010936A1 (en) 1990-12-21 1991-12-20 ADHESIN-OLIGOSACCHARIDE CONJUGATE VACCINE FOR $i(HAEMOPHILUS INFLUENZAE)

Publications (1)

Publication Number Publication Date
DK0565590T3 true DK0565590T3 (da) 1999-09-27

Family

ID=24532360

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92902826T DK0565590T3 (da) 1990-12-21 1991-12-20 Adhesin-oligosaccharid-konjugatvaccine mod Haemophilus influenzae

Country Status (8)

Country Link
EP (1) EP0565590B1 (de)
JP (1) JP3330935B2 (de)
AT (1) ATE176989T1 (de)
CA (1) CA2098598A1 (de)
DE (1) DE69130955T2 (de)
DK (1) DK0565590T3 (de)
ES (1) ES2131066T3 (de)
WO (1) WO1992010936A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2138765C (en) * 1992-06-22 1999-09-07 Howard C. Krivan Recombinant haemophilus influenzae protein and nucleotide sequence encoding same
US5981503A (en) * 1994-06-07 1999-11-09 Connaught Laboratories Limited Analog of Haemophilus Hin47 with reduced protease activity
US5506139A (en) * 1994-07-21 1996-04-09 Connaught Laboratories Limited Analog of haemophilus Hin47 with reduced protease activity
US5939297A (en) * 1994-07-21 1999-08-17 Connaught Laboratories Limited Analog of haemophilus HIN47 with reduced protease activity
RU2196176C2 (ru) * 1994-07-21 2003-01-10 Коннот Лабораториз Лимитед АНАЛОГ HIN47 Haemophilus С РЕДУЦИРОВАННОЙ ПРОТЕАЗНОЙ АКТИВНОСТЬЮ
DE69533102T2 (de) * 1994-07-21 2005-06-02 Aventis Pasteur Ltd., Toronto Analog von haemophilus hin47 mit verminderter protease aktivität
US6147057A (en) * 1994-07-21 2000-11-14 Connaught Laboratories Limited Analog of Haemophilus Hin47 with reduced protease activity
US5681570A (en) 1995-01-12 1997-10-28 Connaught Laboratories Limited Immunogenic conjugate molecules
US5646259A (en) 1995-03-24 1997-07-08 St. Louis University DNA encoding haemophilus adhesion proteins
US5780606A (en) * 1995-06-07 1998-07-14 Connaught Laboratories Limited Neisseria meningitidis capsular polysaccharide conjugates
US9134303B1 (en) 1998-08-25 2015-09-15 Alere Scarborough, Inc. ICT immunoassay for Legionella pneumophila serogroup 1 antigen employing affinity purified antibodies thereto
US6824997B1 (en) 1998-09-18 2004-11-30 Binax, Inc. Process and materials for the rapid detection of streptococcus pneumoniae employing purified antigen-specific antibodies
JP4856836B2 (ja) * 2000-03-01 2012-01-18 バイナックス インコーポレイティッド 標的細菌またはその標的糖質抗原成分の存在を検出する方法
MX2019001167A (es) 2016-07-28 2019-09-16 Max Planck Gesellschaft Derivados sinteticos estables de poliribosilribitolfosfato resistentes a la hidrolisis como vacunas contra haemophilus influenzae tipo b.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78775A (en) * 1985-05-15 1992-06-21 Biotech Australia Pty Ltd Oral vaccines
US5173294A (en) * 1986-11-18 1992-12-22 Research Foundation Of State University Of New York Dna probe for the identification of haemophilus influenzae
NZ223009A (en) * 1986-12-31 1990-06-26 Nl Rivm Of Thoven Oligosaccharides containing d-ribose d-ribitol and phosphate units mimicing haemophilus influenzae type b antigens
EP0320942A3 (de) * 1987-12-18 1989-10-04 American Cyanamid Company Polysaccharide und makromolekulare Verbindungen davon
ES2051909T3 (es) * 1988-04-19 1994-07-01 American Cyanamid Co Vacuna del conjugado de polisacarido-proteina de membrana externa contra la haemophilus influenzae tipo b.
CA2006587C (en) * 1988-12-23 2000-01-18 Robert W. Tolan Membrane proteins and peptides of haemophilus influenzae type b
GB8924473D0 (en) * 1989-10-31 1989-12-20 Connaught Lab Outer membrane protein p1 and peptides of haemophilus influenzae b

Also Published As

Publication number Publication date
WO1992010936A1 (en) 1992-07-09
ATE176989T1 (de) 1999-03-15
EP0565590B1 (de) 1999-03-03
EP0565590A4 (de) 1995-07-05
JPH06508346A (ja) 1994-09-22
ES2131066T3 (es) 1999-07-16
EP0565590A1 (de) 1993-10-20
JP3330935B2 (ja) 2002-10-07
CA2098598A1 (en) 1992-06-22
DE69130955T2 (de) 1999-07-01
DE69130955D1 (de) 1999-04-08

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