DK0778781T3 - Pneumokok-polysaccharid-rekombinant pneumolysin-konjugat-vacciner til immunisering mod pneumokokinfektioner - Google Patents
Pneumokok-polysaccharid-rekombinant pneumolysin-konjugat-vacciner til immunisering mod pneumokokinfektionerInfo
- Publication number
- DK0778781T3 DK0778781T3 DK95930151T DK95930151T DK0778781T3 DK 0778781 T3 DK0778781 T3 DK 0778781T3 DK 95930151 T DK95930151 T DK 95930151T DK 95930151 T DK95930151 T DK 95930151T DK 0778781 T3 DK0778781 T3 DK 0778781T3
- Authority
- DK
- Denmark
- Prior art keywords
- pneumococcal
- polysaccharide
- immunization against
- conjugate vaccines
- infections
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1275—Streptococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/295,305 US5565204A (en) | 1994-08-24 | 1994-08-24 | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
| PCT/US1995/010227 WO1996005859A1 (en) | 1994-08-24 | 1995-08-10 | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0778781T3 true DK0778781T3 (da) | 2001-01-02 |
Family
ID=23137126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95930151T DK0778781T3 (da) | 1994-08-24 | 1995-08-10 | Pneumokok-polysaccharid-rekombinant pneumolysin-konjugat-vacciner til immunisering mod pneumokokinfektioner |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5565204A (da) |
| EP (1) | EP0778781B1 (da) |
| JP (1) | JP3927233B2 (da) |
| KR (1) | KR100385411B1 (da) |
| AT (1) | ATE198051T1 (da) |
| AU (1) | AU704450B2 (da) |
| CA (1) | CA2198251C (da) |
| DE (1) | DE69519634T2 (da) |
| DK (1) | DK0778781T3 (da) |
| ES (1) | ES2152421T3 (da) |
| GR (1) | GR3035081T3 (da) |
| IL (1) | IL115047A (da) |
| PT (1) | PT778781E (da) |
| WO (1) | WO1996005859A1 (da) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6165762A (en) | 1996-08-16 | 2000-12-26 | Smithkline Beecham Corporation | DNA encoding adenine phosphoribosyltransferase from Streptococcus pneumoniae |
| CA2271720A1 (en) * | 1996-10-31 | 1998-05-07 | Human Genome Sciences, Inc. | Streptococcus pneumoniae polynucleotides and sequences |
| JP2001519817A (ja) * | 1997-03-26 | 2001-10-23 | ブリガム アンド ウイメンズ ホスピタル | 糖断片生成法 |
| US6087328A (en) * | 1997-04-24 | 2000-07-11 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Coupling of unmodified proteins to haloacyl or dihaloacyl derivatized polysaccharides for the preparation of protein-polysaccharide vaccines |
| US6676943B1 (en) | 1997-04-24 | 2004-01-13 | Regents Of The University Of Minnesota | Human complement C3-degrading protein from Streptococcus pneumoniae |
| AU740956B2 (en) * | 1997-07-21 | 2001-11-15 | Baxter Healthcare Sa | Modified immunogenic pneumolysin compositions as vaccines |
| US5882898A (en) * | 1997-08-29 | 1999-03-16 | Smithkline Beecham Corporation | Streptococcus pneumoniae polynucleotides which encode folyl-polyglutamate synthetase (FPGS) polypeptides |
| US5965714A (en) * | 1997-10-02 | 1999-10-12 | Connaught Laboratories, Inc. | Method for the covalent attachment of polysaccharides to protein molecules |
| US5861281A (en) * | 1997-10-30 | 1999-01-19 | Smithkline Beecham Corporation | Lacc |
| US6165763A (en) * | 1997-10-30 | 2000-12-26 | Smithkline Beecham Corporation | Ornithine carbamoyltransferase |
| US6274719B1 (en) * | 1998-04-24 | 2001-08-14 | Smithkline Beecham Corporation | Gcp |
| AU763770B2 (en) * | 1998-07-14 | 2003-07-31 | Wyeth Holdings Corporation | Adjuvant and vaccine compositions containing monophosphoryl lipid A |
| US6268177B1 (en) | 1998-09-22 | 2001-07-31 | Smithkline Beecham Corporation | Isolated nucleic acid encoding nucleotide pyrophosphorylase |
| WO2000026359A1 (en) * | 1998-11-04 | 2000-05-11 | Smithkline Beecham Corporation | ftsX |
| JP2002539273A (ja) * | 1999-03-19 | 2002-11-19 | スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム | ワクチン |
| GB9906437D0 (en) * | 1999-03-19 | 1999-05-12 | Smithkline Beecham Biolog | Vaccine |
| WO2001007465A1 (en) * | 1999-07-22 | 2001-02-01 | Smithkline Beecham Corporation | Ga1R |
| GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| GB0022742D0 (en) | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| US7118756B2 (en) * | 2000-12-28 | 2006-10-10 | Wyeth | Recombinant protective protein from Streptococcus pneumoniae |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| CA2493124C (en) | 2002-08-02 | 2014-04-29 | Glaxosmithkline Biologicals S.A. | Vaccine |
| US7785608B2 (en) * | 2002-08-30 | 2010-08-31 | Wyeth Holdings Corporation | Immunogenic compositions for the prevention and treatment of meningococcal disease |
| US7301554B2 (en) * | 2002-09-20 | 2007-11-27 | Ricoh Company, Ltd. | Light scanning device, scanning line adjusting method, scanning line adjusting control method, image forming apparatus, and image forming method |
| MXPA05004528A (es) | 2002-11-01 | 2005-07-26 | Glaxosmithkline Biolog Sa | Composicion inmunogenica. |
| CN100443116C (zh) * | 2002-11-07 | 2008-12-17 | 新纳几美国公司 | 治疗或预防肺炎球菌感染的组合物及其用途 |
| PT1601689E (pt) | 2003-03-13 | 2008-01-04 | Glaxosmithkline Biolog Sa | Processo de purificação para citolisina bacteriana |
| CA2844154C (en) | 2003-08-06 | 2016-12-20 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Polysaccharide-protein conjugate vaccines |
| US8048432B2 (en) | 2003-08-06 | 2011-11-01 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Polysaccharide-protein conjugate vaccines |
| ATE474595T1 (de) | 2003-10-02 | 2010-08-15 | Glaxosmithkline Biolog Sa | B. pertussis antigene und ihre verwendung bei der vakzinierung |
| GB0410220D0 (en) | 2004-05-07 | 2004-06-09 | Kirkham Lea Ann | Mutant pneumolysin proteins |
| GB0502096D0 (en) * | 2005-02-01 | 2005-03-09 | Chiron Srl | Purification of streptococcal capsular polysaccharide |
| GB0505996D0 (en) | 2005-03-23 | 2005-04-27 | Glaxosmithkline Biolog Sa | Fermentation process |
| US20070184072A1 (en) * | 2005-04-08 | 2007-08-09 | Wyeth | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| EP2425853A1 (en) | 2005-04-08 | 2012-03-07 | Wyeth LLC | Multivalent Pneumococcal Polysaccharide-Protein Conjugate Composition |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| BRPI0620460B8 (pt) | 2005-12-22 | 2021-05-25 | Glaxosmithkline Biologicals Sa | uso de composição imunogênica para bebês, e, processo para produzir uma vacina |
| GB0607088D0 (en) * | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| EP1973933B1 (en) | 2006-01-17 | 2020-06-24 | Forsgren, Arne | A NOVEL SURFACE EXPOSED HAEMOPHILUS INFLUENZAE PROTEIN (PROTEIN E; pE) |
| EP2007427A4 (en) | 2006-04-11 | 2012-04-04 | Yeda Res & Dev | IMPROVED VACCINES WITH MULTIMETER HSP60 PEPTIDE SUPPORTS |
| US9370557B2 (en) * | 2006-06-15 | 2016-06-21 | The University Court Of The University Of Glasgow | Adjuvant compounds |
| CN101553246B (zh) * | 2006-08-07 | 2019-05-21 | 哈佛大学校长及研究员协会 | 蛋白质基质疫苗及这种疫苗的制备和给药方法 |
| JP5745221B2 (ja) * | 2006-08-07 | 2015-07-08 | プレジデント アンド フェローズ オブ ハーバード カレッジ | タンパク質マトリックスワクチンおよびそのようなワクチンの製造方法および投与方法 |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| CA2683748C (en) | 2007-04-13 | 2016-02-16 | The Board Of Regents Of The University Of Oklahoma | Mutants of cholesterol-dependent cytolysins and uses thereof |
| WO2009094730A1 (en) * | 2008-02-01 | 2009-08-06 | Newcastle Innovation Limited | Vaccine compositions |
| CN103816870B (zh) | 2008-12-03 | 2016-11-23 | 株式会社钟化 | 含有甲酰基的多孔性载体、使用该多孔性载体的吸附体以及它们的制造方法 |
| GB201003922D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Conjugation process |
| EP2544714A1 (en) | 2010-03-10 | 2013-01-16 | GlaxoSmithKline Biologicals S.A. | Vaccine composition |
| RU2580620C2 (ru) | 2010-08-23 | 2016-04-10 | ВАЙЕТ ЭлЭлСи | СТАБИЛЬНЫЕ КОМПОЗИЦИИ АНТИГЕНОВ Neisseria meningitidis rLP2086 |
| GB201015132D0 (en) | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
| WO2012032489A1 (en) | 2010-09-10 | 2012-03-15 | Wyeth Llc | Non-lipidated variants of neisseria meningitidis orf2086 antigens |
| ITMI20111182A1 (it) | 2011-06-28 | 2012-12-29 | Canio Buonavoglia | Vaccino per coronavirus canino |
| EP2731617A4 (en) | 2011-07-12 | 2015-07-01 | Brigham & Womens Hospital | LIPID-BASED PSA COMPOSITIONS, METHOD FOR THEIR INSULATION AND USE METHOD THEREFOR |
| KR101315599B1 (ko) | 2011-10-25 | 2013-10-10 | 건국대학교 산학협력단 | 폐렴균점막다당질 유형14 (cps14)와 호스래디시 퍼옥시다제의 당단백중합체 |
| CA2865745C (en) | 2012-03-09 | 2018-01-09 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| CA2900008C (en) | 2013-02-07 | 2025-10-07 | Children's Medical Center Corporation | PROTEIN ANTIGENS THAT CONFER PROTECTION AGAINST COLONIZATION AND/OR PNEUMOCOCCAL DISEASE |
| US9802987B2 (en) | 2013-03-08 | 2017-10-31 | Pfizer Inc. | Immunogenic fusion polypeptides |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| SI3096783T1 (sl) * | 2014-01-21 | 2021-09-30 | Pfizer Inc. | Kapsularni polisaharidi streptococcus pneumoniae in njihovi konjugati |
| US9815886B2 (en) | 2014-10-28 | 2017-11-14 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| ES2993430T3 (en) | 2014-11-21 | 2024-12-30 | Univ Oklahoma | Pneumolysin mutants and methods of use thereof |
| AU2016221318B2 (en) | 2015-02-19 | 2020-06-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| JP6918365B2 (ja) | 2015-08-19 | 2021-08-11 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 脂質化psa組成物および方法 |
| US11491181B2 (en) | 2016-07-15 | 2022-11-08 | President And Fellows Of Harvard College | Glycolipid compositions and methods of use |
| MX2019007910A (es) | 2016-12-30 | 2019-12-05 | Sutrovax Inc | Conjugados de polipeptido-antigeno con aminoacidos no naturales. |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| US10183070B2 (en) | 2017-01-31 | 2019-01-22 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| KR20240018698A (ko) | 2017-06-10 | 2024-02-13 | 인벤트프라이즈 인크. | 면역원성과 항원항체 결합성이 개선된 2가 또는 다가 접합체 다당류를 가진 다가 접합체 백신 |
| US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
| EP4034157A1 (en) | 2019-09-27 | 2022-08-03 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| EP3900739A1 (en) * | 2020-04-21 | 2021-10-27 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Synthetic streptococcus pneumoniae saccharide conjugates to conserved membrane protein |
| EP4192499A4 (en) | 2020-08-10 | 2024-09-25 | Inventprise, Inc. | Multivalent pneumococcal glycoconjugate vaccines containing emerging serotype 24f |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4242501A (en) * | 1979-08-08 | 1980-12-30 | American Cyanamid Company | Purification of pneumococcal capsular polysaccharides |
| US4356170A (en) * | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| US4902506A (en) * | 1983-07-05 | 1990-02-20 | The University Of Rochester | Immunogenic conjugates |
| US4673574A (en) * | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US5360897A (en) * | 1981-08-31 | 1994-11-01 | The University Of Rochester | Immunogenic conjugates of streptococcus pneumonial capsular polymer and toxin or in toxiad |
| US4761283A (en) * | 1983-07-05 | 1988-08-02 | The University Of Rochester | Immunogenic conjugates |
| US4686102A (en) * | 1984-04-12 | 1987-08-11 | American Cyanamid Company | Multivalent pneumococcal vaccine and preparation thereof |
| NZ214503A (en) * | 1984-12-20 | 1990-02-26 | Merck & Co Inc | Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins, and methods of preparing such polysaccharides and conjugates |
| US5192540A (en) * | 1988-04-19 | 1993-03-09 | American Cyanamid Company | Haemophilus influenzae type b oxidized polysaccharide-outer membrane protein conjugate vaccine |
| IL92816A0 (en) * | 1988-12-22 | 1990-09-17 | Biogrowth Inc | Recombinant dna molecules,hosts,processes and human somatomedin carrier protein-like polypeptides |
| IL95578A (en) * | 1989-09-15 | 1998-08-16 | Gen Hospital Corp | Conjugate vaccine formed from a polysaccharide and a c protein of b-streptococcus |
| US5153312A (en) * | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| CA2059692C (en) * | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
| US5371197A (en) * | 1991-09-24 | 1994-12-06 | Merck & Co., Inc. | Protein-dimeric polysaccharide conjugate vaccine |
| US5445817A (en) * | 1992-08-21 | 1995-08-29 | The United States Of America As Represented By The Department Of Health And Human Services | Pertussis toxin used as a carrier protein with non-charged saccharides in conjugate vaccines |
-
1994
- 1994-08-24 US US08/295,305 patent/US5565204A/en not_active Expired - Fee Related
-
1995
- 1995-08-10 AT AT95930151T patent/ATE198051T1/de not_active IP Right Cessation
- 1995-08-10 AU AU33636/95A patent/AU704450B2/en not_active Ceased
- 1995-08-10 DE DE69519634T patent/DE69519634T2/de not_active Expired - Fee Related
- 1995-08-10 KR KR1019970701180A patent/KR100385411B1/ko not_active Expired - Fee Related
- 1995-08-10 PT PT95930151T patent/PT778781E/pt unknown
- 1995-08-10 JP JP50814296A patent/JP3927233B2/ja not_active Expired - Fee Related
- 1995-08-10 WO PCT/US1995/010227 patent/WO1996005859A1/en not_active Ceased
- 1995-08-10 CA CA002198251A patent/CA2198251C/en not_active Expired - Fee Related
- 1995-08-10 ES ES95930151T patent/ES2152421T3/es not_active Expired - Lifetime
- 1995-08-10 EP EP95930151A patent/EP0778781B1/en not_active Expired - Lifetime
- 1995-08-10 DK DK95930151T patent/DK0778781T3/da active
- 1995-08-23 IL IL11504795A patent/IL115047A/xx not_active IP Right Cessation
-
2000
- 2000-12-14 GR GR20000402765T patent/GR3035081T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0778781A1 (en) | 1997-06-18 |
| DE69519634T2 (de) | 2001-06-13 |
| ATE198051T1 (de) | 2000-12-15 |
| CA2198251A1 (en) | 1996-02-29 |
| JPH10504717A (ja) | 1998-05-12 |
| US5565204A (en) | 1996-10-15 |
| ES2152421T3 (es) | 2001-02-01 |
| GR3035081T3 (en) | 2001-03-30 |
| PT778781E (pt) | 2001-03-30 |
| WO1996005859A1 (en) | 1996-02-29 |
| KR970705410A (ko) | 1997-10-09 |
| KR100385411B1 (ko) | 2003-12-11 |
| AU3363695A (en) | 1996-03-14 |
| EP0778781B1 (en) | 2000-12-13 |
| CA2198251C (en) | 2007-06-12 |
| AU704450B2 (en) | 1999-04-22 |
| IL115047A0 (en) | 1995-12-08 |
| JP3927233B2 (ja) | 2007-06-06 |
| DE69519634D1 (de) | 2001-01-18 |
| IL115047A (en) | 2005-08-31 |
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