DK0569421T3 - Farmaceutiske forbindelser - Google Patents

Farmaceutiske forbindelser

Info

Publication number: DK0569421T3
Authority: DK; Denmark
Prior art keywords: pharmaceutical compounds; diacylguanine; chloropurine; hydrolysis; amino
Prior art date: 1991-01-31

Application number

DK92903581.4T

Other languages

English (en)

Inventor

John Christopher Hanson

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-01-31

Filing date

1992-01-30

Publication date

1997-09-01

1992-01-30 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

1997-09-01 Application granted granted Critical

1997-09-01 Publication of DK0569421T3 publication Critical patent/DK0569421T3/da

Links

150000001875 compounds Chemical class 0.000 title 1
UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 abstract 2
RYYIULNRIVUMTQ-UHFFFAOYSA-N 6-chloroguanine Chemical compound NC1=NC(Cl)=C2N=CNC2=N1 RYYIULNRIVUMTQ-UHFFFAOYSA-N 0.000 abstract 1
239000012320 chlorinating reagent Substances 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000003444 phase transfer catalyst Substances 0.000 abstract 1
NIUZJTWSUGSWJI-UHFFFAOYSA-M triethyl(methyl)azanium;chloride Chemical compound [Cl-].CC[N+](C)(CC)CC NIUZJTWSUGSWJI-UHFFFAOYSA-M 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK92903581.4T 1991-01-31 1992-01-30 Farmaceutiske forbindelser DK0569421T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB919102127A GB9102127D0 (en)	1991-01-31	1991-01-31	Pharmaceuticals

Publications (1)

Publication Number	Publication Date
DK0569421T3 true DK0569421T3 (da)	1997-09-01

Family

ID=10689331

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92903581.4T DK0569421T3 (da)	1991-01-31	1992-01-30	Farmaceutiske forbindelser

Country Status (19)

Country	Link
US (2)	US5910589A (da)
EP (1)	EP0569421B1 (da)
JP (1)	JP2618578B2 (da)
KR (1)	KR100213936B1 (da)
AT (1)	ATE154803T1 (da)
AU (1)	AU655002B2 (da)
CA (1)	CA2101640C (da)
DE (1)	DE69220565T2 (da)
DK (1)	DK0569421T3 (da)
ES (1)	ES2104892T3 (da)
GB (1)	GB9102127D0 (da)
GR (1)	GR3023917T3 (da)
HK (1)	HK1007312A1 (da)
IE (1)	IE920294A1 (da)
MX (1)	MX9200398A (da)
NZ (1)	NZ241442A (da)
PT (1)	PT100074B (da)
WO (1)	WO1992013859A1 (da)
ZA (1)	ZA92606B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9102127D0 (en) *	1991-01-31	1991-03-13	Smithkline Beecham Plc	Pharmaceuticals
CA2076886C (en) *	1991-11-22	2002-06-11	Masami Igi	Method for production of 2-amino-6-halogenopurine and synthesis intermediate therefor
GB9201961D0 (en) *	1992-01-30	1992-03-18	Smithkline Beecham Plc	Pharmaceuticals
DE4231036A1 (de) *	1992-09-17	1994-03-24	Basf Ag	Verfahren zur Herstellung von 2-Amino-6-halogenpurinen
JPH07133276A (ja) *	1993-09-17	1995-05-23	Jiyuuzen Kagaku Kk	２−アセチルアミノ−６−クロロプリンの製造方法
WO1996021664A1 (de) *	1995-01-09	1996-07-18	Lonza Ag	Verfahren zur herstellung von 2-amino-6-chlorpurin und zwischenprodukte dafür
CA2189088C (en) *	1995-11-09	2005-09-20	Masatoshi Sakai	2-amino-6-chloropurine and method for preparing the same
US6419934B1 (en)	1999-02-24	2002-07-16	Edward L. Tobinick	TNF modulators for treating neurological disorders associated with viral infection
DE60220658T2 (de) *	2001-04-05	2008-02-21	Sumitomo Chemical Co., Ltd.	Verfahren zur produktion von 2,6-dihalogenopurinen
WO2007037790A2 (en) *	2005-06-08	2007-04-05	Elan Corporation, Plc	Modified release famciclovir compositions
EP1852435A1 (en) *	2006-04-12	2007-11-07	SOLMAG S.p.A.	A process for the manufacture of famciclovir using phase-transfer catalysts
CN117466895A (zh) *	2023-10-30	2024-01-30	江苏八巨药业有限公司	一种2-氨基-6-氯嘌呤的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0141927B1 (en) *	1983-08-18	1991-10-30	Beecham Group Plc	Antiviral guanine derivatives
EP0182024B1 (en) *	1984-09-20	1991-04-03	Beecham Group Plc	Purine derivatives and their pharmaceutical use
GB8507606D0 (en) *	1985-03-23	1985-05-01	Beecham Group Plc	Process
GB8916698D0 (en) *	1989-07-21	1989-09-06	Beecham Group Plc	Novel process
DE3941657A1 (de) *	1989-12-16	1991-06-20	Hoechst Ag	Verfahren zur herstellung von 2-acylamino-6-halogen-purin aus 2,9-diacylguanin
GB9102127D0 (en) *	1991-01-31	1991-03-13	Smithkline Beecham Plc	Pharmaceuticals
CA2076886C (en) *	1991-11-22	2002-06-11	Masami Igi	Method for production of 2-amino-6-halogenopurine and synthesis intermediate therefor

1991
- 1991-01-31 GB GB919102127A patent/GB9102127D0/en active Pending
1992
- 1992-01-29 IE IE029492A patent/IE920294A1/en not_active IP Right Cessation
- 1992-01-29 ZA ZA92606A patent/ZA92606B/xx unknown
- 1992-01-29 NZ NZ241442A patent/NZ241442A/en not_active IP Right Cessation
- 1992-01-30 AT AT92903581T patent/ATE154803T1/de not_active IP Right Cessation
- 1992-01-30 AU AU11858/92A patent/AU655002B2/en not_active Ceased
- 1992-01-30 KR KR1019930702265A patent/KR100213936B1/ko not_active Expired - Fee Related
- 1992-01-30 JP JP4503581A patent/JP2618578B2/ja not_active Expired - Fee Related
- 1992-01-30 EP EP92903581A patent/EP0569421B1/en not_active Expired - Lifetime
- 1992-01-30 ES ES92903581T patent/ES2104892T3/es not_active Expired - Lifetime
- 1992-01-30 DK DK92903581.4T patent/DK0569421T3/da active
- 1992-01-30 WO PCT/GB1992/000177 patent/WO1992013859A1/en not_active Ceased
- 1992-01-30 HK HK98106524A patent/HK1007312A1/en not_active IP Right Cessation
- 1992-01-30 PT PT100074A patent/PT100074B/pt not_active IP Right Cessation
- 1992-01-30 DE DE69220565T patent/DE69220565T2/de not_active Expired - Lifetime
- 1992-01-30 US US08/409,490 patent/US5910589A/en not_active Expired - Lifetime
- 1992-01-30 MX MX9200398A patent/MX9200398A/es unknown
- 1992-01-30 CA CA002101640A patent/CA2101640C/en not_active Expired - Lifetime
1997
- 1997-06-26 GR GR970401565T patent/GR3023917T3/el unknown
1999
- 1999-02-26 US US09/261,609 patent/US6093819A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0569421B1 (en)	1997-06-25
KR930703320A (ko)	1993-11-29
GB9102127D0 (en)	1991-03-13
ZA92606B (en)	1992-12-30
PT100074A (pt)	1993-06-30
JP2618578B2 (ja)	1997-06-11
GR3023917T3 (en)	1997-09-30
AU655002B2 (en)	1994-12-01
WO1992013859A1 (en)	1992-08-20
AU1185892A (en)	1992-09-07
DE69220565T2 (de)	1997-12-11
US6093819A (en)	2000-07-25
PT100074B (pt)	1999-06-30
HK1007312A1 (en)	1999-04-09
KR100213936B1 (ko)	1999-08-02
CA2101640C (en)	2002-07-09
IE920294A1 (en)	1992-07-29
NZ241442A (en)	1994-11-25
JPH06504995A (ja)	1994-06-09
MX9200398A (es)	1992-07-01
EP0569421A1 (en)	1993-11-18
US5910589A (en)	1999-06-08
DE69220565D1 (de)	1997-07-31
ES2104892T3 (es)	1997-10-16
ATE154803T1 (de)	1997-07-15
CA2101640A1 (en)	1992-08-01

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