DK0571417T3 - Kombination af IGF-I og IGFBP til anabolisme - Google Patents
Kombination af IGF-I og IGFBP til anabolismeInfo
- Publication number
- DK0571417T3 DK0571417T3 DK92903897.4T DK92903897T DK0571417T3 DK 0571417 T3 DK0571417 T3 DK 0571417T3 DK 92903897 T DK92903897 T DK 92903897T DK 0571417 T3 DK0571417 T3 DK 0571417T3
- Authority
- DK
- Denmark
- Prior art keywords
- igf
- combination
- mammal
- igfbp
- human
- Prior art date
Links
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 title abstract 5
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 title abstract 5
- 102000028416 insulin-like growth factor binding Human genes 0.000 title abstract 2
- 108091022911 insulin-like growth factor binding Proteins 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 3
- 230000001195 anabolic effect Effects 0.000 abstract 2
- 102000018997 Growth Hormone Human genes 0.000 abstract 1
- 108010051696 Growth Hormone Proteins 0.000 abstract 1
- 101000599951 Homo sapiens Insulin-like growth factor I Proteins 0.000 abstract 1
- 102000004374 Insulin-like growth factor binding protein 3 Human genes 0.000 abstract 1
- 108090000965 Insulin-like growth factor binding protein 3 Proteins 0.000 abstract 1
- 102000023732 binding proteins Human genes 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 238000011260 co-administration Methods 0.000 abstract 1
- 239000000122 growth hormone Substances 0.000 abstract 1
- 102000044162 human IGF1 Human genes 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000010254 subcutaneous injection Methods 0.000 abstract 1
- 239000007929 subcutaneous injection Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4743—Insulin-like growth factor binding protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Package Frames And Binding Bands (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/654,436 US5187151A (en) | 1991-02-12 | 1991-02-12 | Use of binding protein with igf-i as an anabolic growth promoting agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0571417T3 true DK0571417T3 (da) | 1996-04-15 |
Family
ID=24624851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92903897.4T DK0571417T3 (da) | 1991-02-12 | 1992-01-13 | Kombination af IGF-I og IGFBP til anabolisme |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5187151A (da) |
| EP (1) | EP0571417B1 (da) |
| JP (1) | JPH06505235A (da) |
| AT (1) | ATE135587T1 (da) |
| CA (1) | CA2101340C (da) |
| DE (1) | DE69209277T2 (da) |
| DK (1) | DK0571417T3 (da) |
| ES (1) | ES2085001T3 (da) |
| GR (1) | GR3019851T3 (da) |
| WO (1) | WO1992013556A1 (da) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5681814A (en) * | 1990-06-07 | 1997-10-28 | Genentech, Inc. | Formulated IGF-I Composition |
| US5374620A (en) * | 1990-06-07 | 1994-12-20 | Genentech, Inc. | Growth-promoting composition and its use |
| US5126324A (en) * | 1990-06-07 | 1992-06-30 | Genentech, Inc. | Method of enhancing growth in patients using combination therapy |
| US5407913A (en) * | 1992-12-03 | 1995-04-18 | Celtrix Pharmaceuticals, Inc. | Method and composition for systemic treatment of tissue injury |
| JPH08500827A (ja) * | 1992-08-26 | 1996-01-30 | セルトリックス ファーマシューティカルズ,インコーポレイテッド | 異化症状および全身性組織創傷の全身的治療方法 |
| US5643867A (en) * | 1992-08-26 | 1997-07-01 | Celtrix Pharmaceuticals, Inc. | Method for treating catabolic conditions |
| US5273961A (en) * | 1992-09-22 | 1993-12-28 | Genentech, Inc. | Method of prophylaxis of acute renal failure |
| ATE143267T1 (de) * | 1992-10-29 | 1996-10-15 | Genentech Inc | Methode zur behandlung oder verhütung von fettleibigkeit |
| CA2146973C (en) * | 1992-10-29 | 2008-09-02 | Patricia R. Segarini | Uses of tgf-.beta. receptor fragment as a therapeutic agent |
| US6124259A (en) * | 1993-01-28 | 2000-09-26 | Celtrix Pharmaceuticals, Inc. | Method for treating ophthalmic disorders with IGFBP |
| CA2154078A1 (en) * | 1993-01-29 | 1994-08-04 | George N. Cox | Wound healing composition |
| US5459051A (en) * | 1993-03-26 | 1995-10-17 | Celtrix Pharmaceuticals, Inc. | Methods and vectors for over-expression of ubiquitin fusion proteins in host cells |
| DE69431631T2 (de) * | 1993-09-20 | 2003-07-31 | Celtrix Pharmaceuticals, Inc. | Behandlung von hematologischen störungen mit einem igf-1/igfbp-3 komplex |
| AU693489B2 (en) * | 1993-11-15 | 1998-07-02 | Celtrix Pharmaceuticals, Inc. | Method of treating neurological disorders |
| US5824642A (en) * | 1994-04-07 | 1998-10-20 | Genentech, Inc. | Treatment of partial growth hormone insensitivity syndrome |
| US6207640B1 (en) * | 1994-04-07 | 2001-03-27 | Genentech, Inc. | Treatment of partial growth hormone insensitivity syndrome |
| AU713275B2 (en) * | 1994-07-20 | 1999-11-25 | Celtrix Pharmaceuticals, Inc. | IGF/IGFBP complex for promoting bone formation and for regulating bone remodeling |
| US5712249A (en) * | 1994-09-08 | 1998-01-27 | Ciba-Geigy Corporation | Use of insulin-like growth factors I and II for inhibition of inflammatory response |
| AUPN271195A0 (en) * | 1995-05-02 | 1995-05-25 | Bunge Meat Industries Ltd. | Method of selecting livestock |
| US5741776A (en) * | 1995-05-22 | 1998-04-21 | Genentech, Inc. | Method of administration of IGF-I |
| US5565428A (en) * | 1995-05-22 | 1996-10-15 | Genentech, Inc. | Method of administration of IGF-I |
| EP0766966A3 (en) * | 1995-09-08 | 2001-02-28 | Eli Lilly And Company | Method of treating insulin resistance |
| US5948757A (en) * | 1996-03-01 | 1999-09-07 | Celtrix Pharmaceuticals, Inc. | High dose IGF-1 therapy |
| US6271196B1 (en) * | 1996-03-05 | 2001-08-07 | Regents Of The University Of Ca | Methods of alleviating neuropathic pain using prosaposin-derived peptides |
| US5747273A (en) * | 1996-05-07 | 1998-05-05 | Diagnostic Systems Laboratories, Inc. | Immunoassay of total insulin-like growth factor binding protein-1 |
| AUPN999096A0 (en) * | 1996-05-22 | 1996-06-13 | Northstar Biologicals Pty Ltd | Peptides, antibodies, vaccines & uses thereof |
| US6593290B1 (en) | 1996-11-01 | 2003-07-15 | Genentech, Inc. | Treatment of inner ear hair cells |
| US6156728A (en) | 1996-11-01 | 2000-12-05 | Genentech, Inc. | Treatment of inner ear hair cells |
| US6066464A (en) * | 1996-12-10 | 2000-05-23 | Diagnostic Systems Laboratories, Inc. | Immunoassay of IGF family of peptides, their binding proteins and related molecules in dried whole blood filter paper spots |
| US5824467A (en) * | 1997-02-25 | 1998-10-20 | Celtrix Pharmaceuticals | Methods for predicting drug response |
| US6514937B1 (en) * | 1997-02-25 | 2003-02-04 | Celtrix Pharmaceuticals, Inc. | Method of treating psychological and metabolic disorders using IGF or IGF/IGFBP-3 |
| US6025368A (en) * | 1997-02-25 | 2000-02-15 | Celtrix Pharmaceuticals, Inc. | Method for treating the symptoms of chronic stress-related disorders using IGF |
| US6015786A (en) * | 1997-02-25 | 2000-01-18 | Celtrix Pharmaceuticals, Inc. | Method for increasing sex steroid levels using IGF or IGF/IGFBP-3 |
| US6420518B1 (en) | 1997-04-04 | 2002-07-16 | Genetech, Inc. | Insulin-like growth factor agonist molecules |
| US6121416A (en) | 1997-04-04 | 2000-09-19 | Genentech, Inc. | Insulin-like growth factor agonist molecules |
| DE69835878T2 (de) * | 1997-05-05 | 2007-04-26 | Mayo Foundation For Medical Education And Research, Rochester | IGFIIE/ IGFBP2 Komplex |
| US6548482B1 (en) | 1997-05-05 | 2003-04-15 | Mayo Foundation For Medical Education And Research | Treatment of osteoporosis |
| US6916790B2 (en) | 1997-05-05 | 2005-07-12 | Mayo Foundation For Medical Education And Research | Treatment of osteoporosis |
| TW586934B (en) * | 1997-05-19 | 2004-05-11 | Sumitomo Pharma | Immunopotentiating composition |
| US6436897B2 (en) * | 1998-06-01 | 2002-08-20 | Celtrix Pharmaceuticals, Inc. | Pharmaceutical formulations for IGF/IGFBP |
| US6417330B1 (en) | 1998-06-01 | 2002-07-09 | Celtrix Pharmaceuticals, Inc. | Insulin-like growth factor binding protein variants |
| CA2345642A1 (en) * | 1998-10-02 | 2000-04-13 | Celtrix Pharmaceuticals, Inc. | Methods for the treatment of non-thyroid disorders |
| US7288516B1 (en) | 1999-09-20 | 2007-10-30 | Celtrix Pharmaceuticals, Inc. | Null IGF for the treatment of cancer |
| PT1141014E (pt) * | 1999-01-06 | 2005-04-29 | Genentech Inc | Variante mutante do factor de crescimento semelhante a insulina (igf-i) |
| WO2001087323A2 (en) | 2000-05-16 | 2001-11-22 | Genentech, Inc. | Method for treating cartilage disorders |
| US20030035788A1 (en) * | 2000-09-19 | 2003-02-20 | Desmond Mascarenhas | Method for use of IGF-binding protein for selective sensitization of target cells in vivo |
| AUPR030900A0 (en) * | 2000-09-22 | 2000-10-12 | Queensland University Of Technology | Growth factor complex |
| IL156435A0 (en) * | 2001-02-09 | 2004-01-04 | Genentech Inc | Crystallization of igf-1 |
| US6887851B2 (en) * | 2001-09-18 | 2005-05-03 | Bioexpertise, Llc | IGF-binding protein-derived peptide |
| AU2002324672B2 (en) * | 2001-09-18 | 2007-11-08 | Bioexpertise, Llc | IGF-binding protein-derived peptide or small molecule |
| US6914049B2 (en) * | 2001-09-18 | 2005-07-05 | Bioexpertise, Llc | IGF-binding protein-derived peptide or small molecule |
| DK2274978T3 (da) | 2003-09-12 | 2015-06-15 | Ipsen Biopharmaceuticals Inc | Fremgangsmåder til behandling af en insulin-lignende vækstfaktor-I(IGF-I)-mangel |
| JP2008511838A (ja) * | 2004-08-30 | 2008-04-17 | テルシカ・インク | インシュリン様成長因子欠乏疾患の診断及び治療のための方法及び装置 |
| EP2148695B1 (en) * | 2007-04-18 | 2014-10-15 | Premacure AB | Method and product for treatment and/or prevention of complications of prematurity |
| US10212614B2 (en) * | 2015-12-31 | 2019-02-19 | Facebook, Inc. | Igniting network nodes in a multi-hop wireless network |
| EP3397644A4 (en) | 2015-12-31 | 2018-12-19 | Siemens Healthcare Diagnostics Inc. | Non-recombinant human insulin-like growth factor binding protein concentrate |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1163880B (it) * | 1983-07-29 | 1987-04-08 | Guido Vergari | Fascetta di legatura |
| JPH0720993B2 (ja) * | 1985-08-22 | 1995-03-08 | グロペップ プロプライエタリー リミテッド | 生長因子 |
| AU627423B2 (en) * | 1987-04-06 | 1992-08-27 | Celtrix Pharmaceuticals, Inc. | Human somatomedin carrier protein subunits and process for producing them |
| DK131988A (da) * | 1988-03-11 | 1989-09-12 | Erasmus University | Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur |
| US5258287A (en) * | 1988-03-22 | 1993-11-02 | Genentech, Inc. | DNA encoding and methods of production of insulin-like growth factor binding protein BP53 |
| AU1955388A (en) * | 1988-04-12 | 1989-11-03 | Synergen, Inc. | Method for potentiating and inhibiting insulin-like growth factor activity |
| DE3822646A1 (de) * | 1988-07-05 | 1990-01-11 | Steag Ag | Verfahren zur gewinnung von sphaerischen feststoffteilchen insbesondere solchen zur verwendung als strahlperlen |
| EP0424416B1 (en) * | 1988-07-15 | 1995-07-19 | Central Sydney Area Health Service | Acid-labile subunit (als) of insulin-like-growth factor (igf) binding protein complex |
| GB8826451D0 (en) * | 1988-11-11 | 1988-12-14 | Sandoz Ltd | Improvements in/relating to organic compounds |
| IL92816A0 (en) * | 1988-12-22 | 1990-09-17 | Biogrowth Inc | Recombinant dna molecules,hosts,processes and human somatomedin carrier protein-like polypeptides |
-
1991
- 1991-02-12 US US07/654,436 patent/US5187151A/en not_active Expired - Lifetime
-
1992
- 1992-01-13 EP EP92903897A patent/EP0571417B1/en not_active Expired - Lifetime
- 1992-01-13 WO PCT/US1992/000345 patent/WO1992013556A1/en not_active Ceased
- 1992-01-13 DK DK92903897.4T patent/DK0571417T3/da active
- 1992-01-13 DE DE69209277T patent/DE69209277T2/de not_active Expired - Lifetime
- 1992-01-13 CA CA002101340A patent/CA2101340C/en not_active Expired - Lifetime
- 1992-01-13 AT AT92903897T patent/ATE135587T1/de not_active IP Right Cessation
- 1992-01-13 ES ES92903897T patent/ES2085001T3/es not_active Expired - Lifetime
- 1992-01-13 JP JP4504577A patent/JPH06505235A/ja active Pending
-
1996
- 1996-05-07 GR GR960401236T patent/GR3019851T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3019851T3 (en) | 1996-08-31 |
| CA2101340A1 (en) | 1992-08-13 |
| CA2101340C (en) | 2003-05-06 |
| DE69209277T2 (de) | 1996-10-31 |
| US5187151A (en) | 1993-02-16 |
| EP0571417B1 (en) | 1996-03-20 |
| WO1992013556A1 (en) | 1992-08-20 |
| EP0571417A1 (en) | 1993-12-01 |
| JPH06505235A (ja) | 1994-06-16 |
| ES2085001T3 (es) | 1996-05-16 |
| DE69209277D1 (de) | 1996-04-25 |
| ATE135587T1 (de) | 1996-04-15 |
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