DK131988A - Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur - Google Patents

Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur

Info

Publication number
DK131988A
DK131988A DK131988A DK131988A DK131988A DK 131988 A DK131988 A DK 131988A DK 131988 A DK131988 A DK 131988A DK 131988 A DK131988 A DK 131988A DK 131988 A DK131988 A DK 131988A
Authority
DK
Denmark
Prior art keywords
binding protein
dna structure
igf binding
vector containing
coding
Prior art date
Application number
DK131988A
Other languages
English (en)
Other versions
DK131988D0 (da
Inventor
Stenwert Leonard Sebastia Drop
Arend Brinkman
Original Assignee
Erasmus University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erasmus University filed Critical Erasmus University
Priority to DK131988A priority Critical patent/DK131988A/da
Publication of DK131988D0 publication Critical patent/DK131988D0/da
Priority to PCT/NL1989/000008 priority patent/WO1989008667A1/en
Priority to EP89903815A priority patent/EP0404812A1/en
Priority to AU32965/89A priority patent/AU3296589A/en
Priority to JP1503492A priority patent/JPH03504494A/ja
Publication of DK131988A publication Critical patent/DK131988A/da
Priority to DK216690A priority patent/DK216690A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743Insulin-like growth factor binding protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK131988A 1988-03-11 1988-03-11 Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur DK131988A (da)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DK131988A DK131988A (da) 1988-03-11 1988-03-11 Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur
PCT/NL1989/000008 WO1989008667A1 (en) 1988-03-11 1989-03-10 Recombinant igf binding protein (ibp-1)
EP89903815A EP0404812A1 (en) 1988-03-11 1989-03-10 Recombinant igf binding protein (ibp-1)
AU32965/89A AU3296589A (en) 1988-03-11 1989-03-10 Recombinant igf binding protein (ibp-1)
JP1503492A JPH03504494A (ja) 1988-03-11 1989-03-10 Igf結合タンパク質、igf結合タンパク質をコードするdna構造体及びこのdna構造体を含有したベクター
DK216690A DK216690A (da) 1988-03-11 1990-09-10 Rekombinant ifg-bindingsprotein (ibp-1)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK131988A DK131988A (da) 1988-03-11 1988-03-11 Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur

Publications (2)

Publication Number Publication Date
DK131988D0 DK131988D0 (da) 1988-03-11
DK131988A true DK131988A (da) 1989-09-12

Family

ID=8103523

Family Applications (1)

Application Number Title Priority Date Filing Date
DK131988A DK131988A (da) 1988-03-11 1988-03-11 Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur

Country Status (5)

Country Link
EP (1) EP0404812A1 (da)
JP (1) JPH03504494A (da)
AU (1) AU3296589A (da)
DK (1) DK131988A (da)
WO (1) WO1989008667A1 (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5973115A (en) * 1987-05-15 1999-10-26 Amgen Inc. Method for potentiating and inhibiting insulin-like growth factor activity
US5258287A (en) * 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
ATE132164T1 (de) * 1988-04-12 1996-01-15 Amgen Boulder Inc Verfahren zur steigerung und zur hemmung der wirkung eines insulinähnlichen wachstumfaktors
US5324820A (en) * 1988-07-15 1994-06-28 Central Sydney Area Health Service Acid-labile subunit (ALS) of insulin-like growth factor binding protein complex
CA1341598C (en) * 1988-07-15 2009-09-29 Central Sydney Area Health Service Acid-labile sub-unit (als) of insulin-like growth factor binding proteincomplex
US6465423B1 (en) 1988-07-15 2002-10-15 Central Sydney Area Health Service Acid-labile subunit (ALS) of insulin-like growth factor binding protein complex
GB8826451D0 (en) * 1988-11-11 1988-12-14 Sandoz Ltd Improvements in/relating to organic compounds
WO1992003152A1 (en) * 1990-08-28 1992-03-05 Chiron Corporation New insulin-like growth factor binding protein (igfbp-4)
PT98805B (pt) * 1990-08-28 1999-01-29 Chiron Corp Processo de preparacao de uma nova proteina de ligacao ao factor de crescimento semelhante a insulina (igfbp-4)
US5212074A (en) * 1990-08-28 1993-05-18 Chiron Corporation Genetic material encoding new insulin-like growth factor binding protein igfbp-6
US6326154B1 (en) 1990-11-19 2001-12-04 Genentech, Inc. Ligand-mediated immunofunctional hormone binding protein assay method
US5210017A (en) * 1990-11-19 1993-05-11 Genentech, Inc. Ligand-mediated immunofunctional hormone binding protein assay method
EP0556344B1 (en) 1991-01-08 2003-08-13 Chiron Corporation New insulin-like growth factor binding protein
US5198340A (en) * 1991-01-17 1993-03-30 Genentech, Inc. Assay for free igf-i, igf-ii, and gh levels in body fluids
US5187151A (en) * 1991-02-12 1993-02-16 Genentech, Inc. Use of binding protein with igf-i as an anabolic growth promoting agent
US6420172B1 (en) 1992-04-20 2002-07-16 Tib Company, Llc Method for inducing tumor immunity
US5407913A (en) * 1992-12-03 1995-04-18 Celtrix Pharmaceuticals, Inc. Method and composition for systemic treatment of tissue injury
ATE243712T1 (de) 1992-11-04 2003-07-15 Chiron Corp Vekürztes insulinähnlichen wachstumsfaktor- bindendes protein mit mitogener aktivität
US6124259A (en) * 1993-01-28 2000-09-26 Celtrix Pharmaceuticals, Inc. Method for treating ophthalmic disorders with IGFBP
AU6626794A (en) * 1993-04-07 1994-10-24 Amgen Boulder Inc. Methods of using insulin-like growth factor binding proteins
EP0723453B1 (en) * 1993-08-03 2000-03-15 Celtrix Pharmaceuticals, Inc. Method of treating reproductive disorders
US7026299B2 (en) 1994-07-12 2006-04-11 Human Genome Sciences, Inc. Connective tissue growth factor-2
EP1217067A2 (en) 1994-07-12 2002-06-26 Human Genome Sciences, Inc. Connective tissue growth factor-2
CA2195474A1 (en) * 1994-07-20 1996-02-01 Cedo Martin Bagi Igf/igfbp complex for promoting bone formation and for regulating bone remodeling
US5747280A (en) * 1995-06-05 1998-05-05 Human Genome Sciences, Inc. Human vascular IBP-like growth factor
US5994302A (en) * 1994-12-09 1999-11-30 Human Genome Sciences, Inc. Human vascular IBP-like growth factor
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
US6420518B1 (en) 1997-04-04 2002-07-16 Genetech, Inc. Insulin-like growth factor agonist molecules
JP2002535967A (ja) 1999-01-06 2002-10-29 ジェネンテック・インコーポレーテッド インシュリン様成長因子(igf)i変異体
AU762351B2 (en) 1999-01-06 2003-06-26 Genentech Inc. Insulin-like growth factor (IGF) I mutant variants
ATE389416T1 (de) 2000-05-16 2008-04-15 Genentech Inc Behandlung von knorpelerkrankungen
WO2002072780A2 (en) 2001-03-14 2002-09-19 Genentech, Inc. Igf antagonist peptides
EP2274978B1 (en) 2003-09-12 2015-05-20 Tercica, Inc. Methods for treatment of insulin-like growth factor-I(IGF-I) deficiency
US7192738B2 (en) 2003-10-03 2007-03-20 Genentech, Inc. IGF binding proteins
CA3075482A1 (en) 2017-09-11 2019-03-14 Shire Human Genetic Therapies, Inc. Methods and compositions for treating chronic lung diseases
MX2023004426A (es) 2020-10-19 2023-08-04 Oak Hill Bio Ltd Composiciones adecuadas para su uso en neonatos.
AU2023210427A1 (en) 2022-01-19 2024-08-22 Oak Hill Bio Limited Compositions and methods for reducing oxidation of igf‐1/igfbp
WO2023242439A1 (en) 2022-06-17 2023-12-21 Oak Hill Bio Limited Vascular stabilisation (preterm infants)
WO2023242440A1 (en) 2022-06-17 2023-12-21 Oak Hill Bio Limited Treament of lungs in infants
WO2023242442A1 (en) 2022-06-17 2023-12-21 Oak Hill Bio Limited Method of maturing/differentiating neurons and/or modulating the vagus nerve
CN120882420A (zh) 2023-02-14 2025-10-31 奥克希尔生物有限公司 Gi组织中愈合失调的治疗

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3338480A1 (de) * 1983-10-22 1985-05-02 Behringwerke Ag, 3550 Marburg Neues protein pp(pfeil abwaerts)2(pfeil abwaerts)(pfeil abwaerts)0(pfeil abwaerts), verfahren zu seiner gewinnung sowie seine verwendung

Also Published As

Publication number Publication date
DK131988D0 (da) 1988-03-11
AU3296589A (en) 1989-10-05
EP0404812A1 (en) 1991-01-02
JPH03504494A (ja) 1991-10-03
WO1989008667A1 (en) 1989-09-21

Similar Documents

Publication Publication Date Title
DK131988D0 (da) Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur
DK217889A (da) Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase
DK40086A (da) Formaldehyd-bindemiddel, fremgangsmaade til fremstilling deraf og anvendelse deraf
DE3669112D1 (de) Tourenskibindung.
DK100985D0 (da) Dna, der koder for human tumornecrosefaktor, samt humant tumornecrosefaktor-polypeptid og fremgangsmaader til fremstilling heraf
DK108189D0 (da) Chimere antistoffer rettet mod humant carcinoembryonalt antigen og metal-chelater samt dna-sekvenser, der koder for saadanne antistoffer
DK122687A (da) Polypeptid, dna og anvendelse deraf
DK4387D0 (da) Human-praepo-insulinlignende-vaerkstfaktor i samt gener og syntetiske dna-sekvenser, som koder for denne
FI863175L (fi) Terraengskidbindning.
DK589085D0 (da) Rekombinant dna-udtrykkelsesvektor, der er funktionel og udvaelgelig iplanter
FI840105A7 (fi) Menetelmä homologisen Bacillus- promoottorin ja yhdistetyn luonnon tai modifioidun, ribosomin sitomiskohdan sisältävän DNA-sekvenssin käyttö Streptomyces:ssä.
DK178386D0 (da) Rekombinant dna-udtrykkelsesvektor og dna-forbindelser, der udtrykker isopenicillin n synthetase
NO904024L (no) Heparin-bindende proteiner, dna som koder for dem, fremgangsmaater for fremstilling derav og terapeutisk preparater inneholdende dem.
DK300787A (da) Dna-struktur fra cytomegalivirus, ekspressionsvektor derfor samt dermed kodede proteinstrukturer og disses anvendelse
GB8801877D0 (en) Nucleotide sequence encoding plant ribosome inactivating protein
GB8404378D0 (en) Dna sequence recombinant dna molecules
DK102088D0 (da) Rekombinant-dna-udtrykkelsesvektorer og dna-produkter, der koder deacetoxycephalosporin c syntetase og deacetylsephalosporin c synthetase
DK606088A (da) Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n synthetase
DK224985A (da) Peptider, og midler indeholdende peptiderne
IL88095A0 (en) Dna sequences,proteins and gene preparations
NO842682L (no) Polypeptid og dna-sekvens samt vektor
DK174933B1 (da) Modificeret hygromycin B-resistens DNA-sekvens samt plasmider, vektorer og transformanter indeholdende denne DNA-sekvens
DK151788D0 (da) Hybridserpiner og dna, som koder derfor
FI865146L (fi) Skidbindning.
DE3669034D1 (de) Skibindung.

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment