DK0578511T3 - Spirooxathiolan-quinuclidinderivat til behandling af Sjögrens syndrom - Google Patents

Spirooxathiolan-quinuclidinderivat til behandling af Sjögrens syndrom

Info

Publication number: DK0578511T3
Authority: DK; Denmark
Prior art keywords: spirooxathiolan; sjögren; syndrome; treatment; quinuclidine
Prior art date: 1992-07-10

Application number

DK93305423T

Other languages

English (en)

Inventor

Nobuaki Abe

Yasuyoshi Takeshita

Original Assignee

Snow Brand Milk Products Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-07-10

Filing date

1993-07-09

Publication date

2000-04-03

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16540522&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0578511(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1993-07-09 Application filed by Snow Brand Milk Products Co Ltd filed Critical Snow Brand Milk Products Co Ltd

2000-04-03 Application granted granted Critical

2000-04-03 Publication of DK0578511T3 publication Critical patent/DK0578511T3/da

Links

208000021386 Sjogren Syndrome Diseases 0.000 title abstract 2
UANSQQFYKHHDJM-KRWDZBQOSA-N n-[(3r)-1-azabicyclo[2.2.2]octan-3-yl]naphthalene-1-carboxamide Chemical compound C1=CC=C2C(C(N[C@@H]3C4CCN(CC4)C3)=O)=CC=CC2=C1 UANSQQFYKHHDJM-KRWDZBQOSA-N 0.000 title 1
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
SBYHFKPVCBCYGV-UHFFFAOYSA-N quinuclidine Chemical compound C1CC2CCN1CC2 SBYHFKPVCBCYGV-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Immunology (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK93305423T 1992-07-10 1993-07-09 Spirooxathiolan-quinuclidinderivat til behandling af Sjögrens syndrom DK0578511T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP4207485A JP2683783B2 (ja)	1992-07-10	1992-07-10	シェーグレン症候群治療剤

Publications (1)

Publication Number	Publication Date
DK0578511T3 true DK0578511T3 (da)	2000-04-03

Family

ID=16540522

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93305423T DK0578511T3 (da)	1992-07-10	1993-07-09	Spirooxathiolan-quinuclidinderivat til behandling af Sjögrens syndrom

Country Status (15)

Country	Link
US (1)	US5340821A (da)
EP (1)	EP0578511B1 (da)
JP (1)	JP2683783B2 (da)
KR (1)	KR100331046B1 (da)
AT (1)	ATE184483T1 (da)
AU (1)	AU666734B2 (da)
CA (1)	CA2099970C (da)
DE (1)	DE69326395T2 (da)
DK (1)	DK0578511T3 (da)
ES (1)	ES2138613T3 (da)
IL (1)	IL106218A (da)
NO (1)	NO303765B1 (da)
NZ (1)	NZ248099A (da)
TW (1)	TW230750B (da)
ZA (1)	ZA934883B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2852608B2 (ja) *	1994-06-27	1999-02-03	雪印乳業株式会社	口腔乾燥症治療剤
US6140374A (en) *	1998-10-23	2000-10-31	Abbott Laboratories	Propofol composition
JP4447685B2 (ja) *	1999-01-14	2010-04-07	第一三共株式会社	皮膚乾燥症治療剤
JP2006070027A (ja) *	2004-08-06	2006-03-16	Dai Ichi Seiyaku Co Ltd	口腔粘膜投与剤
WO2006013914A1 (ja) *	2004-08-06	2006-02-09	Daiichi Pharmaceutical Co., Ltd.	口腔粘膜投与剤
CN101031297A (zh) *	2004-10-05	2007-09-05	安斯泰来制药有限公司	眼干燥症和口干燥症治疗用医药组合物
EP2258359A3 (en)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation with sabcomelin
JP2009506069A (ja)	2005-08-26	2009-02-12	ブレインセルス，インコーポレイティド	ムスカリン性受容体調節による神経発生
US7985756B2 (en)	2005-10-21	2011-07-26	Braincells Inc.	Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en)	2005-10-31	2007-05-10	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
WO2007134077A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	5 ht receptor mediated neurogenesis
WO2007134136A2 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
EP2068872A1 (en)	2006-09-08	2009-06-17	Braincells, Inc.	Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
US8143400B2 (en) *	2008-01-10	2012-03-27	Apotex Pharmachem Inc.	Process for the preparation and purification of cis-2-methylspiro(1,3-oxathiolane-5,3′)quiniclidine hydrochloride
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
JP5595513B2 (ja)	2009-11-12	2014-09-24	アカシアファーマリミテッド	口腔乾燥症の治療のためのベタネコールの使用
GB201107533D0 (en)	2011-05-06	2011-06-22	Acacia Pharma Ltd	Formulaiton
CN102846607A (zh) *	2012-04-09	2013-01-02	珠海亿邦制药股份有限公司	一种以盐酸西维美林为活性成分的固体制剂及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4001396A (en) *	1971-08-04	1977-01-04	Chinoin Pharmaceutical And Chemical Works Ltd.	Hormonal product extracted from parathyroid gland and process for the preparation thereof
US4110441A (en) *	1974-04-29	1978-08-29	Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.	Gamma-l-glutamyl cholamine phosphate
US4100271A (en) *	1976-02-26	1978-07-11	Cooper Laboratories, Inc.	Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4701450A (en) *	1984-03-21	1987-10-20	Akzo N.V.	Steroids for use as immunomodulators
US4855290A (en) *	1985-05-10	1989-08-08	State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research	Derivatives of quinuclidine
US4684727A (en) *	1985-07-29	1987-08-04	Schering Corporation	Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents
ZA868369B (en) *	1986-01-10	1987-11-25	Israel State	Derivatives of quinuclidine
GB8717446D0 (en) *	1987-07-23	1987-08-26	Merck Sharp & Dohme	Chemical compounds
US4876260A (en) *	1987-10-28	1989-10-24	State Of Israel, Israel Institute Of Biological Research	Oxathiolanes
CA1303503C (en) *	1987-11-10	1992-06-16	Marc Plamondon	Ophthalmic solution comprising iodine-polyvinylpyrrolidone complex
WO1990005525A1 (en) *	1988-11-23	1990-05-31	Pfizer Inc.	Quinuclidine derivatives as substance p antagonists
US4997654A (en) *	1989-08-14	1991-03-05	Warner-Lambert Company	Method for increasing salivation for xerostomia patients
US5242930A (en) *	1991-02-11	1993-09-07	Merck Sharp & Dohme Ltd.	Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy

1992
- 1992-07-10 JP JP4207485A patent/JP2683783B2/ja not_active Expired - Lifetime
1993
- 1993-07-02 IL IL10621893A patent/IL106218A/xx not_active IP Right Cessation
- 1993-07-06 CA CA002099970A patent/CA2099970C/en not_active Expired - Lifetime
- 1993-07-06 TW TW082105361A patent/TW230750B/zh active
- 1993-07-06 KR KR1019930012594A patent/KR100331046B1/ko not_active Expired - Lifetime
- 1993-07-07 NZ NZ248099A patent/NZ248099A/xx not_active IP Right Cessation
- 1993-07-07 AU AU41819/93A patent/AU666734B2/en not_active Expired
- 1993-07-07 ZA ZA934883A patent/ZA934883B/xx unknown
- 1993-07-07 US US08/088,304 patent/US5340821A/en not_active Expired - Lifetime
- 1993-07-09 AT AT93305423T patent/ATE184483T1/de active
- 1993-07-09 DK DK93305423T patent/DK0578511T3/da active
- 1993-07-09 DE DE69326395T patent/DE69326395T2/de not_active Expired - Lifetime
- 1993-07-09 ES ES93305423T patent/ES2138613T3/es not_active Expired - Lifetime
- 1993-07-09 EP EP93305423A patent/EP0578511B1/en not_active Expired - Lifetime
- 1993-07-09 NO NO932520A patent/NO303765B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
NZ248099A (en)	1999-07-29
US5340821A (en)	1994-08-23
KR100331046B1 (ko)	2002-08-19
ES2138613T3 (es)	2000-01-16
NO303765B1 (no)	1998-08-31
ZA934883B (en)	1994-02-03
AU666734B2 (en)	1996-02-22
NO932520L (no)	1994-01-11
EP0578511B1 (en)	1999-09-15
AU4181993A (en)	1994-01-13
TW230750B (da)	1994-09-21
CA2099970C (en)	2003-12-30
NO932520D0 (no)	1993-07-09
DE69326395D1 (de)	1999-10-21
ATE184483T1 (de)	1999-10-15
IL106218A (en)	1997-02-18
DE69326395T2 (de)	2000-04-20
CA2099970A1 (en)	1994-01-11
JP2683783B2 (ja)	1997-12-03
IL106218A0 (en)	1993-11-15
JPH0624981A (ja)	1994-02-01
KR940005274A (ko)	1994-03-21
EP0578511A1 (en)	1994-01-12

Publication	Publication Date	Title
ATE184483T1 (de)	1999-10-15	Spirooxathiolan-quinuclidin-derivat zur behandlung des sjögren-syndroms
ATE117685T1 (de)	1995-02-15	Chinoloncarbonsäure-derivate.
NL300407I1 (nl)	2009-11-02	Difluoroprostaglandinederivaten en hun toepassing
DK0493608T3 (da)	1996-02-19	Quinoloncarboxylsyrederivat
DE68914292D1 (de)	1994-05-11	Zusammensetzung zur Behandlung von ischämischen Störungen in Organen.
DK1063228T5 (da)	2009-06-15	Cycloalkenderivater, fremgangsmåde til fremstilling deraf og anvendelse deraf
ATE74608T1 (de)	1992-04-15	Chinolincarbonsaeure-derivate.
DK0508740T3 (da)	1997-10-20	Thiazolidindionderivater, deres fremstilling og anvendelse.
NO982873D0 (no)	1998-06-19	1-metylkarbapenemderivater
ATE134376T1 (de)	1996-03-15	Mono- und bis-alkylaminoanthracycline
NO173991C (no)	1994-03-02	Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,2,5-ditiazocin-derivater
ATE146481T1 (de)	1997-01-15	Epoxysuccinamidsäurederivat
DE69001004D1 (de)	1993-04-08	Zusammensetzung gegen leberkrankheiten.
DK360388A (da)	1989-01-02	Laegemiddel til behandling af hjerteinsufficiens
DE69411852D1 (de)	1998-08-27	Indolderivate, ihre Salze und sie enthaltende Arzneimittel zur Behandlung von Herzkrankheiten
DK0551844T3 (da)	1999-04-12	Svovlholdige galdesyrederivater
ATE95697T1 (de)	1993-10-15	Uricosuretische zusammensetzung.
DE69532963D1 (de)	2004-06-03	Verwendung von 4-acylaminopyridin derivaten zur Herstellung eines Medikaments für die Behandlung von zerebrovaskulären Erkrankungen
DE3782229D1 (de)	1992-11-19	Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten.
ATE189813T1 (de)	2000-03-15	Prostaglandin-i-analoga
DE69007777D1 (de)	1994-05-05	Derivate der p-Guanidinobenzoesäure zur Behandlung der zerebrovaskulären Kontraktion.
BR9101765A (pt)	1991-12-17	Processo para a preparacao de um composto
DE69424677D1 (de)	2000-06-29	Präparat zur behandlung der drogenabhängigkeit