DK0579939T3 - Phospholipidderivater - Google Patents

Phospholipidderivater

Info

Publication number: DK0579939T3
Authority: DK; Denmark
Prior art keywords: phospholipid; medicaments; preparation processes; phospholipid derivatives; processes therefor
Prior art date: 1992-07-11

Application number

DK93108904T

Other languages

English (en)

Inventor

Juergen Prof Engel

Wolfgang Dr Schumacher

Gerhard Dr Noessner

Bernhard Dr Kutscher

Peter Dr Hilgard

Jurij Dr Stekar

Original Assignee

Asta Medica Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-07-11

Filing date

1993-06-03

Publication date

1999-09-20

1993-06-03 Application filed by Asta Medica Ag filed Critical Asta Medica Ag

1999-09-20 Application granted granted Critical

1999-09-20 Publication of DK0579939T3 publication Critical patent/DK0579939T3/da

Links

150000003904 phospholipids Chemical class 0.000 title abstract 2
239000003814 drug Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
- C07F9/106—Adducts, complexes, salts of phosphatides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/5532—Seven-(or more) membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Physical Education & Sports Medicine (AREA)
Tropical Medicine & Parasitology (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Dermatology (AREA)
AIDS & HIV (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Inorganic Compounds Of Heavy Metals (AREA)

DK93108904T 1992-07-11 1993-06-03 Phospholipidderivater DK0579939T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4222910A DE4222910A1 (de)	1992-07-11	1992-07-11	Neue Phospholipidderivate

Publications (1)

Publication Number	Publication Date
DK0579939T3 true DK0579939T3 (da)	1999-09-20

Family

ID=6463031

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93108904T DK0579939T3 (da)	1992-07-11	1993-06-03	Phospholipidderivater

Country Status (31)

Country	Link
EP (1)	EP0579939B1 (da)
JP (1)	JP3311431B2 (da)
KR (1)	KR100297180B1 (da)
CN (1)	CN1039012C (da)
AT (1)	ATE176477T1 (da)
AU (1)	AU664101B2 (da)
BR (1)	BR9302809A (da)
CA (2)	CA2100228C (da)
CZ (1)	CZ290863B6 (da)
DE (2)	DE4222910A1 (da)
DK (1)	DK0579939T3 (da)
EE (1)	EE03140B1 (da)
ES (1)	ES2129053T3 (da)
FI (1)	FI111262B (da)
GR (1)	GR3029602T3 (da)
HR (1)	HRP931046B1 (da)
HU (1)	HU218783B (da)
IL (1)	IL106289A (da)
LT (1)	LT3113B (da)
LV (1)	LV10870B (da)
MX (1)	MX9304133A (da)
NO (1)	NO306468B1 (da)
PL (3)	PL173388B1 (da)
RU (1)	RU2108336C1 (da)
SG (1)	SG46249A1 (da)
SI (1)	SI9300365B (da)
SK (1)	SK283827B6 (da)
TW (1)	TW304956B (da)
UA (1)	UA40567C2 (da)
YU (1)	YU49079B (da)
ZA (1)	ZA934971B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5475234B2 (ja)	2005-01-21	2014-04-16	アステックス・セラピューティクス・リミテッド	医薬化合物
CA2632449A1 (en) *	2005-12-19	2007-06-28	Aeterna Zentaris Gmbh	Alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof
EP1800684A1 (en) *	2005-12-20	2007-06-27	Zentaris GmbH	Novel alkyl phospholipid derivatives and uses thereof
EP1869981A1 (de) *	2006-06-21	2007-12-26	Staatliches Weinbauinstitut Freiburg	Alkylphospholipide und Lyso-Phospholipide zur Bekämpfung von Pflanzenpathogenen
WO2008044041A1 (en)	2006-10-12	2008-04-17	Astex Therapeutics Limited	Pharmaceutical combinations
JP5528807B2 (ja)	2006-10-12	2014-06-25	アステックス、セラピューティックス、リミテッド	複合薬剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4444766A (en) *	1980-10-21	1984-04-24	Boehringer Mannheim Gmbh	Sulfur-containing phospholipid compounds and therapeutic compositions
JPS5984824A (ja) *	1982-11-08	1984-05-16	Takeda Chem Ind Ltd	抗腫瘍剤
DE3530767A1 (de) *	1985-08-28	1987-03-12	Max Planck Gesellschaft	Mittel gegen multiple sklerose
CA1280369C (en) *	1985-12-04	1991-02-19	Hansjorg Eibl	Pharmaceutical with anti-tumor effect
EP0257762B1 (en) *	1986-07-14	1990-10-10	Nippon Chemiphar Co., Ltd.	Novel glycerol derivative and anti-hypertensive agent
EP0284395B1 (en) *	1987-03-24	1993-06-23	Nippon Chemiphar Co., Ltd.	Novel glycerol derivative and anti-hypertensive agent
DE3906952A1 (de) *	1989-03-04	1990-09-06	Boehringer Mannheim Gmbh	(3-(c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)6(pfeil abwaerts)-c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)8(pfeil abwaerts))alkansulfinyl- und sulfonyl-2-methoxymethyl-propyl)-(2-trimethylammonio-ethyl) phosphate, verfahren zu deren herstellung diese verbindungen enthaltende arzneimittel
DE3942933A1 (de) *	1989-12-23	1991-06-27	Boehringer Mannheim Gmbh	Verwendung von alkylphospholipiden als antivirale arzneimittel und neue phospholipid-derivate
DE4114586A1 (de) *	1991-05-04	1992-11-05	Boehringer Mannheim Gmbh	Arzneimittel enthaltend azacyclodiphosphonsaeurederivate, neue azacyclodiphosphonsaeurederivate sowie verfahren zu deren herstellung

1992
- 1992-07-11 DE DE4222910A patent/DE4222910A1/de not_active Ceased
1993
- 1993-06-01 TW TW082104345A patent/TW304956B/zh not_active IP Right Cessation
- 1993-06-03 AT AT93108904T patent/ATE176477T1/de active
- 1993-06-03 DK DK93108904T patent/DK0579939T3/da active
- 1993-06-03 ES ES93108904T patent/ES2129053T3/es not_active Expired - Lifetime
- 1993-06-03 EP EP93108904A patent/EP0579939B1/de not_active Expired - Lifetime
- 1993-06-03 DE DE59309355T patent/DE59309355D1/de not_active Expired - Lifetime
- 1993-06-03 SG SG1996001626A patent/SG46249A1/en unknown
- 1993-06-04 LT LTIP620A patent/LT3113B/lt not_active IP Right Cessation
- 1993-06-23 CZ CZ19931249A patent/CZ290863B6/cs not_active IP Right Cessation
- 1993-06-28 SK SK670-93A patent/SK283827B6/sk not_active IP Right Cessation
- 1993-07-06 YU YU47393A patent/YU49079B/sh unknown
- 1993-07-08 PL PL93299624A patent/PL173388B1/pl unknown
- 1993-07-08 JP JP16911493A patent/JP3311431B2/ja not_active Expired - Lifetime
- 1993-07-08 PL PL93318679A patent/PL177811B1/pl unknown
- 1993-07-08 NO NO932502A patent/NO306468B1/no not_active IP Right Cessation
- 1993-07-08 PL PL93318680A patent/PL175607B1/pl unknown
- 1993-07-09 FI FI933165A patent/FI111262B/fi not_active IP Right Cessation
- 1993-07-09 HR HR931046A patent/HRP931046B1/xx not_active IP Right Cessation
- 1993-07-09 UA UA93002052A patent/UA40567C2/uk unknown
- 1993-07-09 ZA ZA934971A patent/ZA934971B/xx unknown
- 1993-07-09 IL IL10628993A patent/IL106289A/xx not_active IP Right Cessation
- 1993-07-09 MX MX9304133A patent/MX9304133A/es active IP Right Grant
- 1993-07-09 AU AU41864/93A patent/AU664101B2/en not_active Expired
- 1993-07-09 RU RU93047049A patent/RU2108336C1/ru active
- 1993-07-09 BR BR9302809A patent/BR9302809A/pt not_active Application Discontinuation
- 1993-07-09 CA CA002100228A patent/CA2100228C/en not_active Expired - Lifetime
- 1993-07-09 HU HU9301992A patent/HU218783B/hu unknown
- 1993-07-09 SI SI9300365A patent/SI9300365B/sl unknown
- 1993-07-09 CA CA002511753A patent/CA2511753C/en not_active Expired - Lifetime
- 1993-07-10 KR KR1019930012980A patent/KR100297180B1/ko not_active Expired - Lifetime
- 1993-07-10 CN CN93108564A patent/CN1039012C/zh not_active Expired - Lifetime
- 1993-07-12 LV LVP-93-988A patent/LV10870B/lv unknown
1994
- 1994-10-25 EE EE9400199A patent/EE03140B1/xx unknown
1999
- 1999-03-08 GR GR990400689T patent/GR3029602T3/el unknown

Also Published As

Publication number	Publication date
PL177811B1 (pl)	2000-01-31
NO932502L (no)	1994-01-12
UA40567C2 (uk)	2001-08-15
YU47393A (sh)	1997-08-22
LV10870A (lv)	1995-10-20
JP3311431B2 (ja)	2002-08-05
DE59309355D1 (de)	1999-03-18
PL175607B1 (pl)	1999-01-29
CN1039012C (zh)	1998-07-08
BR9302809A (pt)	1994-03-15
GR3029602T3 (en)	1999-06-30
AU4186493A (en)	1994-01-13
SI9300365B (sl)	2002-02-28
NO932502D0 (no)	1993-07-08
AU664101B2 (en)	1995-11-02
SG46249A1 (en)	1998-02-20
TW304956B (da)	1997-05-11
HRP931046B1 (en)	2000-06-30
HU9301992D0 (en)	1993-09-28
CA2511753C (en)	2007-09-25
DE4222910A1 (de)	1994-01-13
KR100297180B1 (ko)	2001-11-30
NO306468B1 (no)	1999-11-08
CZ124993A3 (en)	1995-03-15
MX9304133A (es)	1994-04-29
ZA934971B (en)	1994-02-01
PL173388B1 (pl)	1998-02-27
HUT64548A (en)	1994-01-28
CA2511753A1 (en)	1994-01-12
LV10870B (en)	1996-06-20
CN1084175A (zh)	1994-03-23
CA2100228C (en)	2006-01-24
PL299624A1 (en)	1994-02-21
FI933165A0 (fi)	1993-07-09
SK283827B6 (sk)	2004-02-03
KR940002265A (ko)	1994-02-17
FI933165A7 (fi)	1994-01-12
JPH0733791A (ja)	1995-02-03
HRP931046A2 (en)	1997-04-30
HU218783B (hu)	2000-12-28
EP0579939A1 (de)	1994-01-26
SK67093A3 (en)	1995-03-08
EE03140B1 (et)	1998-12-15
ATE176477T1 (de)	1999-02-15
YU49079B (sh)	2003-08-29
CZ290863B6 (cs)	2002-11-13
ES2129053T3 (es)	1999-06-01
FI111262B (fi)	2003-06-30
RU2108336C1 (ru)	1998-04-10
LTIP620A (en)	1994-07-15
LT3113B (en)	1994-12-27
CA2100228A1 (en)	1994-01-12
IL106289A0 (en)	1994-04-12
SI9300365A (en)	1994-03-31
IL106289A (en)	2000-06-01
EP0579939B1 (de)	1999-02-03

Publication	Publication Date	Title
ATE494009T1 (de)	2011-01-15	Prodrugs, ihre herstellung und verwendung als arzneimittel
PT83872A (de)	1987-01-01	Arzneimittel
ATE98480T1 (de)	1994-01-15	Arzneimittelformulierungen.
DE68920455D1 (de)	1995-02-23	Cyclohexenderivate.
ES544787A0 (es)	1986-06-16	Preparaciones medicinales solidas
DK0579939T3 (da)	1999-09-20	Phospholipidderivater
FI893366A0 (fi)	1989-07-11	4-piperidylmetyl-2,3-dihydro-1h -isoindol- och 2,3,4,5-tetrahydro-1h-bensasepinderivat, deras framstaellning och terapeutiska anvaendning.
DE58902310D1 (de)	1992-10-29	Tetrahydropyridin-derivate.
IT8622051A1 (it)	1988-04-17	Composizioni farmaceutiche ad attivita' cicatrizzante
ATE66481T1 (de)	1991-09-15	Pyranobenzoxadiazolderivate, herstellung, verwendung und diese enthaltende zubereitungen.
DE58908003D1 (de)	1994-08-11	Cyclohexen-Derivate.