DK0590327T3 - Påvisning af nukleinsyrer i blod - Google Patents

Påvisning af nukleinsyrer i blod

Info

Publication number
DK0590327T3
DK0590327T3 DK93113861T DK93113861T DK0590327T3 DK 0590327 T3 DK0590327 T3 DK 0590327T3 DK 93113861 T DK93113861 T DK 93113861T DK 93113861 T DK93113861 T DK 93113861T DK 0590327 T3 DK0590327 T3 DK 0590327T3
Authority
DK
Denmark
Prior art keywords
blood
detection
nucleic acids
nucleic
acids
Prior art date
Application number
DK93113861T
Other languages
English (en)
Inventor
Jean Burckhardt
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0590327T3 publication Critical patent/DK0590327T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK93113861T 1992-09-11 1993-08-31 Påvisning af nukleinsyrer i blod DK0590327T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH287592 1992-09-11

Publications (1)

Publication Number Publication Date
DK0590327T3 true DK0590327T3 (da) 2003-07-28

Family

ID=4243543

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93113861T DK0590327T3 (da) 1992-09-11 1993-08-31 Påvisning af nukleinsyrer i blod

Country Status (7)

Country Link
US (1) US5501963A (da)
EP (1) EP0590327B1 (da)
JP (1) JP3727667B2 (da)
CA (1) CA2105944C (da)
DE (1) DE69332852T2 (da)
DK (1) DK0590327T3 (da)
ES (1) ES2194843T3 (da)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7785852B2 (en) * 1992-12-07 2010-08-31 Third Wave Technologies, Inc. Cleavage of nucleic acids
US6372424B1 (en) * 1995-08-30 2002-04-16 Third Wave Technologies, Inc Rapid detection and identification of pathogens
DE69520328T2 (de) * 1994-11-08 2001-08-23 Canon K.K., Tokio/Tokyo Toner für die Entwicklung elektrostatischer Bilder, Zwei-Komponenten-Entwickler, Entwicklungsmethode, Bilderzeugungsverfahren, Hitzefixierverfahren und Verfahren zur Herstellung von Tonern
US5935825A (en) * 1994-11-18 1999-08-10 Shimadzu Corporation Process and reagent for amplifying nucleic acid sequences
AT406019B (de) * 1995-05-08 2000-01-25 Immuno Ag Verfahren zur herstellung eines arzneimittels enthaltend ein oder mehrere plasmaderivate
JP3494509B2 (ja) * 1995-06-28 2004-02-09 株式会社島津製作所 核酸合成法
JP3452717B2 (ja) * 1996-03-08 2003-09-29 株式会社島津製作所 核酸合成法
US6235471B1 (en) 1997-04-04 2001-05-22 Caliper Technologies Corp. Closed-loop biochemical analyzers
EP0972082A4 (en) * 1997-04-04 2007-04-25 Caliper Life Sciences Inc BIOCHEMICAL ANALYZERS OPERATING IN CLOSED LOOP
US6391622B1 (en) * 1997-04-04 2002-05-21 Caliper Technologies Corp. Closed-loop biochemical analyzers
US5939259A (en) * 1997-04-09 1999-08-17 Schleicher & Schuell, Inc. Methods and devices for collecting and storing clinical samples for genetic analysis
US20080064108A1 (en) * 1997-12-10 2008-03-13 Tony Baker Urine Preservation System
US7569342B2 (en) * 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
WO1999036574A1 (en) 1998-01-20 1999-07-22 Mayo Foundation For Medical Education And Research Simplified mutation detection
US6146511A (en) * 1998-01-30 2000-11-14 The Perkin-Elmer Corporation Electrophoretic nucleic acid purification method
AU3534199A (en) * 1998-04-23 1999-11-08 Takara Shuzo Co., Ltd. Method For Synthesizing DNA
WO2000075356A1 (en) * 1999-06-04 2000-12-14 Lin Shi Lung Rna polymerase chain reaction
JP2001029078A (ja) * 1999-07-16 2001-02-06 Shimadzu Corp Rna増幅法
AT410218B (de) 1999-08-20 2003-03-25 Baxter Ag Verfahren zur herstellung eines qualitätsgesicherten pools biologischer proben
GB9922971D0 (en) * 1999-09-29 1999-12-01 Secr Defence Reaction system
JP4519247B2 (ja) * 2000-03-09 2010-08-04 シスメックス株式会社 核酸の抽出精製用試薬
JP3724321B2 (ja) * 2000-03-21 2005-12-07 株式会社島津製作所 核酸合成法
JP4470275B2 (ja) * 2000-04-27 2010-06-02 株式会社島津製作所 核酸合成法
EP1334113A4 (en) * 2000-10-20 2007-08-08 Expression Diagnostics Inc EVALUATION OF LEUCOCYTAIRE EXPRESSION LEVEL
US20080261220A1 (en) * 2000-11-30 2008-10-23 Third Wave Technologies, Inc. Nucleic Acid Detection Assays
US20020165675A1 (en) * 2001-03-03 2002-11-07 Golovlev Valeri V. Method and microelectronic device for multi-site molecule detection
GB0110476D0 (en) 2001-04-30 2001-06-20 Secr Defence Reagent delivery system
US6905827B2 (en) * 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US7235358B2 (en) 2001-06-08 2007-06-26 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US7026121B1 (en) * 2001-06-08 2006-04-11 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
EA006679B1 (ru) * 2001-06-12 2006-02-24 Такара Био Инк. Способ стабилизации реагента для амплификации или детекции нуклеиновой кислоты и способ хранения
US6977162B2 (en) * 2002-03-01 2005-12-20 Ravgen, Inc. Rapid analysis of variations in a genome
NZ535044A (en) * 2002-03-01 2008-12-24 Ravgen Inc Non-invasive method to determine the genetic sequence of foetal DNA from a sample from a pregnant female thereby detecting any alternation in gene sequence as compared with the wild type sequence
US20050266455A1 (en) * 2002-03-02 2005-12-01 Sci Tec, Inc. Method and microelectronic device for multi-site molecule detection
US7442506B2 (en) * 2002-05-08 2008-10-28 Ravgen, Inc. Methods for detection of genetic disorders
US20070178478A1 (en) * 2002-05-08 2007-08-02 Dhallan Ravinder S Methods for detection of genetic disorders
US7727720B2 (en) * 2002-05-08 2010-06-01 Ravgen, Inc. Methods for detection of genetic disorders
AU2003253651C1 (en) 2002-06-14 2010-06-03 Gen-Probe Incorporated Compositions and methods for detecting hepatitis B virus
KR100475309B1 (ko) * 2002-11-05 2005-03-11 한국전자통신연구원 Pcr 파라미터의 주기적 변화를 수반한 다중 pcr수행 방법
AU2003268333A1 (en) * 2003-02-28 2004-09-28 Ravgen, Inc. Methods for detection of genetic disorders
WO2004094986A2 (en) * 2003-04-16 2004-11-04 Handylab, Inc. System and method for electrochemical detection of biological compounds
US7892745B2 (en) * 2003-04-24 2011-02-22 Xdx, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US20060263813A1 (en) * 2005-05-11 2006-11-23 Expression Diagnostics, Inc. Methods of monitoring functional status of transplants using gene panels
WO2005038041A2 (en) * 2003-10-16 2005-04-28 Third Wave Technologies, Inc. Direct nucleic acid detection in bodily fluids
DK1718967T3 (da) 2004-02-03 2013-06-03 Diadexus Inc Metoder til at detektere Lp-PLA2 aktivitet
US7462475B2 (en) * 2004-05-20 2008-12-09 Dna Poleymerase Technology, Inc. Use of whole blood in PCR reactions
US7575864B2 (en) * 2004-05-27 2009-08-18 E.I. Du Pont De Nemours And Company Method for the direct detection of diagnostic RNA
US7776530B2 (en) * 2004-06-29 2010-08-17 Wallac Oy Integrated nucleic acid analysis
WO2006029184A2 (en) * 2004-09-08 2006-03-16 Expression Diagnostics, Inc. Genes useful for diagnosing and monitoring inflammation related disorders
JP2008518621A (ja) * 2004-11-03 2008-06-05 サード・ウェーブ・テクノロジーズ・インク 一段階検出アッセイ法
JP2008531039A (ja) * 2005-02-28 2008-08-14 バイオクエスト インク 核酸分子が含まれる直接酵素反応方法
CA2648580A1 (en) * 2006-04-07 2008-05-02 Xdx, Inc. Steroid responsive nucleic acid expression and prediction of disease activity
WO2008018469A1 (en) 2006-08-09 2008-02-14 Arkray, Inc. Method for production of pcr amplification product and use thereof
WO2008021431A2 (en) * 2006-08-14 2008-02-21 Xdx, Inc. Methods and compositions for diagnosing and monitoring the status of transplant rejection and immune disorders
JP5457184B2 (ja) * 2006-09-14 2014-04-02 ディエヌエイ・ポリメラーゼ・テクノロジー・インコーポレイテッド Pcr阻害物質の存在下におけるdna増幅のためのtaqポリメラーゼ変異体酵素の使用
US20110294168A1 (en) * 2006-10-18 2011-12-01 Roche Molecular Systems, Inc. Dna polymerases and related methods
US8962293B2 (en) 2006-10-18 2015-02-24 Roche Molecular Systems, Inc. DNA polymerases and related methods
US8148067B2 (en) * 2006-11-09 2012-04-03 Xdx, Inc. Methods for diagnosing and monitoring the status of systemic lupus erythematosus
CA3006347A1 (en) * 2007-07-23 2009-01-29 Clondiag Gmbh Methods and devices for determining values indicative of the presence and/or amount of nucleic acids
KR101419980B1 (ko) * 2008-03-15 2014-07-15 홀로직, 인크. 증폭 반응 도중에 핵산 분자를 분석하기 위한 조성물 및 방법
HRP20150280T1 (hr) 2008-06-30 2015-04-10 Life Technologies Corporation Postupak za izravno pojačanje iz neprerađenih uzoraka nukleinske kiseline
JP5572939B2 (ja) * 2008-10-27 2014-08-20 株式会社島津製作所 Dnaの塩基配列決定法
WO2010061347A1 (en) * 2008-11-27 2010-06-03 Szerodiagnosztikum Ltd. Pcr based diagnostic method for the identification of clinically important candida species
CN103687961B (zh) * 2011-05-06 2022-11-22 赛雷纳(中国)医疗科技有限公司 用于等温全基因组扩增的方法和组合物
US9464331B2 (en) 2011-07-06 2016-10-11 Quest Diagnostics Investments Incorporated Direct amplification and detection of viral and bacterial pathogens
GB2501238B (en) 2012-03-16 2018-10-24 Cambridge Entpr Ltd Methods for obtaining liquid from a solid phase
EP2859119A2 (en) * 2012-06-12 2015-04-15 Institute for Systems Biology Complex rna composition of bodily fluids
AU2013202808B2 (en) 2012-07-31 2014-11-13 Gen-Probe Incorporated System and method for performing multiplex thermal melt analysis
EP2743355B1 (en) * 2012-12-13 2016-08-10 F. Hoffmann-La Roche AG HAV detection
JP6493209B2 (ja) * 2013-08-06 2019-04-03 東洋紡株式会社 核酸増幅法
JP6428997B2 (ja) * 2013-08-06 2018-11-28 東洋紡株式会社 核酸増幅法
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
WO2016183294A1 (en) 2015-05-12 2016-11-17 Dna Polymerase Technology, Inc. Mutant polymerases and uses thereof
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
US12378543B2 (en) 2017-10-19 2025-08-05 Streck Llc Compositions for hemolysis and coagulation regulation and stabilization of extracellular vesicles
CA3092365A1 (en) * 2018-03-17 2019-09-26 University Of Central Florida Research Foundation, Inc. Detection of interaction between an assay substance and blood or blood components for immune status evaluation disease detection
GB201812428D0 (en) * 2018-07-31 2018-09-12 Bg Res Ltd Improved method for pathogen detection
US20220056542A1 (en) * 2020-08-18 2022-02-24 Nantcell, Inc. Rapid Viral Diagnostic Test
CN115305279A (zh) * 2022-09-16 2022-11-08 上海箴愿生物技术有限公司 一种免基因组提取的快速hla分型方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE462497B (sv) * 1988-11-30 1990-07-02 Clas Fredrik Runesson Kaelland Saett foer att aktivitetsbestaemma polymeraser
US5334499A (en) * 1989-04-17 1994-08-02 Eastman Kodak Company Methods of extracting, amplifying and detecting a nucleic acid from whole blood or PBMC fraction
US5035996A (en) * 1989-06-01 1991-07-30 Life Technologies, Inc. Process for controlling contamination of nucleic acid amplification reactions
EP0415755B1 (en) * 1989-09-01 1995-12-20 Life Technologies Inc. Process for controlling contamination of oligonucleotide-dependent nucleic acid amplification reactions
US5284940A (en) * 1990-11-14 1994-02-08 Hri Research, Inc. Preparation for nucleic acid samples

Also Published As

Publication number Publication date
DE69332852D1 (de) 2003-05-15
JPH06277062A (ja) 1994-10-04
US5501963A (en) 1996-03-26
EP0590327A3 (en) 1997-02-05
EP0590327A2 (en) 1994-04-06
DE69332852T2 (de) 2003-12-04
CA2105944C (en) 2005-10-25
CA2105944A1 (en) 1994-03-12
ES2194843T3 (es) 2003-12-01
EP0590327B1 (en) 2003-04-09
JP3727667B2 (ja) 2005-12-14

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