DK0603414T3 - (-)-Ritodrin - Google Patents
(-)-RitodrinInfo
- Publication number
- DK0603414T3 DK0603414T3 DK93914933.2T DK93914933T DK0603414T3 DK 0603414 T3 DK0603414 T3 DK 0603414T3 DK 93914933 T DK93914933 T DK 93914933T DK 0603414 T3 DK0603414 T3 DK 0603414T3
- Authority
- DK
- Denmark
- Prior art keywords
- ritodrine
- hydroxyphenyl
- remedy
- ritodrines
- opanol
- Prior art date
Links
- 229960001634 ritodrine Drugs 0.000 title abstract 3
- IOVGROKTTNBUGK-SJKOYZFVSA-N (1S,2R)-ritodrine Chemical compound N([C@H](C)[C@@H](O)C=1C=CC(O)=CC=1)CCC1=CC=C(O)C=C1 IOVGROKTTNBUGK-SJKOYZFVSA-N 0.000 abstract 1
- 208000005171 Dysmenorrhea Diseases 0.000 abstract 1
- 206010013935 Dysmenorrhoea Diseases 0.000 abstract 1
- 208000005107 Premature Birth Diseases 0.000 abstract 1
- 206010036590 Premature baby Diseases 0.000 abstract 1
- 208000036029 Uterine contractions during pregnancy Diseases 0.000 abstract 1
- 206010000210 abortion Diseases 0.000 abstract 1
- 231100000176 abortion Toxicity 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000000031 ethylamino group Chemical group [H]C([H])([H])C([H])([H])N([H])[*] 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
- C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
- C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17408792 | 1992-07-01 | ||
| JP21048292 | 1992-08-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0603414T3 true DK0603414T3 (da) | 1997-04-14 |
Family
ID=26495813
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93914933.2T DK0603414T3 (da) | 1992-07-01 | 1993-06-30 | (-)-Ritodrin |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5449694A (fr) |
| EP (1) | EP0603414B1 (fr) |
| JP (1) | JP2758502B2 (fr) |
| KR (1) | KR0151114B1 (fr) |
| CN (1) | CN1040319C (fr) |
| AT (1) | ATE148880T1 (fr) |
| CA (1) | CA2116685C (fr) |
| DE (1) | DE69308115T2 (fr) |
| DK (1) | DK0603414T3 (fr) |
| ES (1) | ES2100544T3 (fr) |
| WO (1) | WO1994001392A1 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06247846A (ja) * | 1993-02-22 | 1994-09-06 | Toko Yakuhin Kogyo Kk | 塩酸リトドリンの経皮吸収製剤用組成物 |
| KR100358319B1 (ko) * | 1993-11-16 | 2002-10-25 | 쉐링 악티엔게젤샤프트 | 산화질소 합성효소 기질, 산화질소 공여체, 또는 산화질소저해제를 포함하는 자궁 수축성 질환의 치료용 약물 |
| FR2720276B1 (fr) * | 1994-05-24 | 1997-09-05 | Christophe Boyer | Nouvelle utilisation thérapeutique des agents bétamimétiques et médicament en contenant. |
| WO1997019680A1 (fr) * | 1995-11-28 | 1997-06-05 | Christophe Boyer | Utilisation therapeutique d'agents betamimetiques pour traiter les douleurs menstruelles par voie permuqueuse |
| CN1077600C (zh) * | 1998-12-04 | 2002-01-09 | 中国科学院化工冶金研究所 | 用大规模培养的麻黄细胞培养物作原料生产麻黄碱的方法 |
| AU2002212749A1 (en) * | 2000-11-09 | 2002-05-21 | Mitsui Chemicals, Inc. | Optically active amine derivative and method of synthesis |
| JP4834333B2 (ja) * | 2005-06-27 | 2011-12-14 | アルプス薬品工業株式会社 | 光学活性ベンジルアミン誘導体の製造方法 |
| CN101239917B (zh) * | 2008-03-10 | 2011-05-04 | 苏州立新制药有限公司 | 一种盐酸利托君及其中间体的制备方法 |
| IT1399912B1 (it) | 2010-04-29 | 2013-05-09 | Lundbeck Pharmaceuticals Italy S Pa | Processo di preparazione di ritodrina cloridrato. |
| CN103113237B (zh) * | 2013-03-11 | 2014-04-30 | 苏州立新制药有限公司 | 一种盐酸利托君的制备方法 |
| CN103113239B (zh) * | 2013-03-11 | 2014-04-30 | 苏州立新制药有限公司 | 盐酸利托君的制备方法 |
| CN107382753B (zh) * | 2017-07-24 | 2019-08-23 | 广东众生药业股份有限公司 | 一种高纯度盐酸利托君的制备方法 |
| CN115317471A (zh) * | 2022-05-13 | 2022-11-11 | 海南久常制药有限公司 | 一种盐酸利托君原料药及其片剂制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU639846B2 (en) * | 1990-12-24 | 1993-08-05 | Duphar International Research B.V. | Method for the preparation of erythro vicinal amino-alcohols |
-
1993
- 1993-06-30 DE DE69308115T patent/DE69308115T2/de not_active Expired - Fee Related
- 1993-06-30 DK DK93914933.2T patent/DK0603414T3/da active
- 1993-06-30 EP EP93914933A patent/EP0603414B1/fr not_active Expired - Lifetime
- 1993-06-30 KR KR1019940700661A patent/KR0151114B1/ko not_active Expired - Fee Related
- 1993-06-30 ES ES93914933T patent/ES2100544T3/es not_active Expired - Lifetime
- 1993-06-30 WO PCT/JP1993/000896 patent/WO1994001392A1/fr not_active Ceased
- 1993-06-30 US US08/204,160 patent/US5449694A/en not_active Expired - Fee Related
- 1993-06-30 JP JP5519689A patent/JP2758502B2/ja not_active Expired - Lifetime
- 1993-06-30 CA CA002116685A patent/CA2116685C/fr not_active Expired - Fee Related
- 1993-06-30 AT AT93914933T patent/ATE148880T1/de active
- 1993-07-01 CN CN93116246A patent/CN1040319C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69308115D1 (de) | 1997-03-27 |
| ATE148880T1 (de) | 1997-02-15 |
| EP0603414A1 (fr) | 1994-06-29 |
| US5449694A (en) | 1995-09-12 |
| CA2116685A1 (fr) | 1994-01-20 |
| ES2100544T3 (es) | 1997-06-16 |
| JP2758502B2 (ja) | 1998-05-28 |
| CN1040319C (zh) | 1998-10-21 |
| DE69308115T2 (de) | 1997-05-28 |
| WO1994001392A1 (fr) | 1994-01-20 |
| EP0603414A4 (fr) | 1994-11-30 |
| KR0151114B1 (ko) | 1998-10-15 |
| EP0603414B1 (fr) | 1997-02-12 |
| CA2116685C (fr) | 1999-11-23 |
| CN1087079A (zh) | 1994-05-25 |
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