DK0606318T3 - Vanadiumholdige præparater - Google Patents

Vanadiumholdige præparater

Info

Publication number: DK0606318T3
Authority: DK; Denmark
Prior art keywords: vanadium; containing preparations; compositions; oxovanadium; monoprotic
Prior art date: 1991-09-30

Application number

DK92920526T

Other languages

English (en)

Inventor

John Hugh Mcneill

Hamid Reza Hoveyda

Chris Orvig

Original Assignee

Univ British Columbia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-30

Filing date

1992-09-29

Publication date

1998-09-23

1992-09-29 Application filed by Univ British Columbia filed Critical Univ British Columbia

1998-09-23 Application granted granted Critical

1998-09-23 Publication of DK0606318T3 publication Critical patent/DK0606318T3/da

Links

229910052720 vanadium Inorganic materials 0.000 title abstract 2
LEONUFNNVUYDNQ-UHFFFAOYSA-N vanadium atom Chemical compound [V] LEONUFNNVUYDNQ-UHFFFAOYSA-N 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title 1
XPCTZQVDEJYUGT-UHFFFAOYSA-N 3-hydroxy-2-methyl-4-pyrone Chemical compound CC=1OC=CC(=O)C=1O XPCTZQVDEJYUGT-UHFFFAOYSA-N 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
206010020772 Hypertension Diseases 0.000 abstract 1
HYMLWHLQFGRFIY-UHFFFAOYSA-N Maltol Natural products CC1OC=CC(=O)C1=O HYMLWHLQFGRFIY-UHFFFAOYSA-N 0.000 abstract 1
208000008589 Obesity Diseases 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
BEJNERDRQOWKJM-UHFFFAOYSA-N kojic acid Chemical compound OCC1=CC(=O)C(O)=CO1 BEJNERDRQOWKJM-UHFFFAOYSA-N 0.000 abstract 1
229960004705 kojic acid Drugs 0.000 abstract 1
WZNJWVWKTVETCG-UHFFFAOYSA-N kojic acid Natural products OC(=O)C(N)CN1C=CC(=O)C(O)=C1 WZNJWVWKTVETCG-UHFFFAOYSA-N 0.000 abstract 1
239000003446 ligand Substances 0.000 abstract 1
229940043353 maltol Drugs 0.000 abstract 1
235000020824 obesity Nutrition 0.000 abstract 1
MHHDXUNFNAZUGB-UHFFFAOYSA-N oxidovanadium(2+) Chemical compound [V+2]=O MHHDXUNFNAZUGB-UHFFFAOYSA-N 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Hematology (AREA)
Endocrinology (AREA)
Inorganic Chemistry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Inorganic Compounds Of Heavy Metals (AREA)
Medicinal Preparation (AREA)
Anti-Oxidant Or Stabilizer Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK92920526T 1991-09-30 1992-09-29 Vanadiumholdige præparater DK0606318T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/767,510 US5300496A (en)	1991-09-30	1991-09-30	Complexed vanadium for the treatment of diabetes mellitus
PCT/EP1992/002235 WO1993006811A2 (en)	1991-09-30	1992-09-29	Vanadium compositions

Publications (1)

Publication Number	Publication Date
DK0606318T3 true DK0606318T3 (da)	1998-09-23

Family

ID=25079727

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92920526T DK0606318T3 (da)	1991-09-30	1992-09-29	Vanadiumholdige præparater

Country Status (13)

Country	Link
US (1)	US5300496A (da)
EP (2)	EP0606318B1 (da)
JP (1)	JP3515107B2 (da)
AT (1)	ATE162716T1 (da)
AU (1)	AU2649792A (da)
CA (1)	CA2120338A1 (da)
DE (1)	DE69224293T2 (da)
DK (1)	DK0606318T3 (da)
ES (1)	ES2112329T3 (da)
GR (1)	GR3026654T3 (da)
NZ (1)	NZ244569A (da)
WO (1)	WO1993006811A2 (da)
ZA (1)	ZA927522B (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5866563A (en) *	1991-09-30	1999-02-02	The University Of British Columbia	Vanadium compositions
US5527790A (en) *	1991-09-30	1996-06-18	The University Of British Columbia	Bis(maltolato)oxovanadium compositions for the treatment of elevated blood sugar
GB9305735D0 (en) *	1993-03-19	1993-05-05	North John R	Novel agent for controlling cell activity
US5871779A (en) *	1994-01-18	1999-02-16	Mount Sinai Hospital Corporation	Treatment of arthropathies with vanadate compounds or analogues thereof
US5565491A (en) *	1994-01-31	1996-10-15	Bristol-Myers Squibb Company	Use of phosphotyrosine phospatase inhibitors for controlling cellular proliferation
US5863519A (en) *	1994-08-18	1999-01-26	Nycomed Imaging As	Composition and method of MRI using both a positive and a negative contrast agent
WO1996005867A2 (en) *	1994-08-18	1996-02-29	Nycomed Imaging A/S	Compositions
GB9416767D0 (en) *	1994-08-18	1994-10-12	Nycomed Innovation Ab	Compositions
GB9416768D0 (en) *	1994-08-18	1994-10-12	Nycomed Innovation Ab	Compositions
US5547685A (en) *	1995-05-16	1996-08-20	Eli Lilly And Company	Methods for inhibiting bone loss with vanadyl sulfate
US5545661A (en) *	1995-05-16	1996-08-13	Eli Lilly And Company	Methods for inhibiting bone loss with bis-pyrone oxovanadium compounds
US5885980A (en) *	1996-06-25	1999-03-23	Enrique G. Gutierrez	Composition and method for treating diabetes
US5962030A (en)	1997-03-07	1999-10-05	Akesis Pharmaceuticals, Inc.	Dietary supplement and method of treatment for diabetic control
AU7022198A (en) *	1997-04-24	1998-11-24	Angiotech Pharmaceuticals, Inc.	Vanadium complexes and derivatives thereof and methods related thereto
US6232340B1 (en)	1997-04-24	2001-05-15	Angiotech Pharmaceuticals, Inc.	Vanadium complexes and derivatives thereof and methods related thereto
US6245808B1 (en) *	1998-11-05	2001-06-12	Parker Hughes Institute	Oxy-vanadium (IV) complexes having spermicidal activity
US6432941B1 (en) *	1998-01-20	2002-08-13	Parker Hughes Institute	Vanadium compounds for treating cancer
EP1113804A2 (en) *	1998-09-17	2001-07-11	Akesis Pharmaceuticals, Inc.	Combinations of chromium or vanadium with antidiabetics for glucose metabolism disorders
US6376549B1 (en) *	1998-09-17	2002-04-23	Akesis Pharmaceuticals, Inc.	Metforimin-containing compositions for the treatment of diabetes
AU5613999A (en)	1998-09-18	2000-04-10	University Of British Columbia, The	Pharmaceutical compositions of vanadium biguanide complexes and their use
WO2000024730A1 (en) *	1998-10-28	2000-05-04	The University Of British Columbia	Organic vanadium(iii) complexes and their use
GB2396106B (en) *	2002-12-12	2006-11-15	Johnson & Johnson Medical Ltd	Wound dressings comprising enzyme inhibitors
AU2005259231A1 (en) *	2004-07-02	2006-01-12	Genmedica Therapeutics Sl	Arylalkylamine vanadium (V) salts for the treatment and/or prevention of diabetes mellitus
WO2006064061A1 (en) *	2004-12-16	2006-06-22	Genmedica Therapeutics Sl	Amines, combination of amines and vanadium and amine vanadium salts for the treatment or prevention of dyslipidemia
US20070066682A1 (en) *	2005-07-01	2007-03-22	Exposito Miriam R	Arylalkylamine vanadium (V) salts for the treatment and/or prevention of Diabetes mellitus
US20080070987A1 (en) *	2006-05-12	2008-03-20	Francesc Yraola Font	Meta-xylylenediamine vanadate salts
BR112013022907A2 (pt)	2011-03-07	2016-09-13	Cfm Pharma Holding Bv	composição farmacêutica
WO2012131689A1 (en)	2011-03-25	2012-10-04	Chaudhuri Mihir K	Insulin mimetic active comprising oxodiperoxo vanadates and a pharamaceutical composition obtained thereof
EP3988092B1 (en) *	2019-06-24	2026-01-28	Shenzhen Fangshengtai Medical Technology Co., Ltd.	Oxovanadium complexes for use in the treatment of pain
CN111035652B (zh) *	2020-01-08	2021-08-24	辽宁大学	钒酸盐酪蛋白复合物在制备降糖药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1277599C (en) *	1986-10-16	1990-12-11	Barry I. Posner	Vanadium - peroxide compositions as insulin mimickers
FR2619382B1 (fr) *	1987-08-11	1990-05-04	Lazaro Rene	Compose organo-mineral de vanadyle, procede d'obtention d'un tel compose, composition pharmaceutique contenant ce compose organo-mineral
JPH02292217A (ja) *	1989-05-08	1990-12-03	Otsuka Pharmaceut Co Ltd	糖尿病治療薬

1991
- 1991-09-30 US US07/767,510 patent/US5300496A/en not_active Expired - Lifetime
1992
- 1992-09-29 DK DK92920526T patent/DK0606318T3/da active
- 1992-09-29 WO PCT/EP1992/002235 patent/WO1993006811A2/en not_active Ceased
- 1992-09-29 EP EP92920526A patent/EP0606318B1/en not_active Expired - Lifetime
- 1992-09-29 ES ES92920526T patent/ES2112329T3/es not_active Expired - Lifetime
- 1992-09-29 CA CA002120338A patent/CA2120338A1/en not_active Abandoned
- 1992-09-29 DE DE69224293T patent/DE69224293T2/de not_active Expired - Fee Related
- 1992-09-29 JP JP50659193A patent/JP3515107B2/ja not_active Expired - Fee Related
- 1992-09-29 AT AT92920526T patent/ATE162716T1/de not_active IP Right Cessation
- 1992-09-29 AU AU26497/92A patent/AU2649792A/en not_active Abandoned
- 1992-09-29 EP EP97200558A patent/EP0811380A3/en not_active Withdrawn
- 1992-09-30 NZ NZ244569A patent/NZ244569A/en unknown
- 1992-09-30 ZA ZA927522A patent/ZA927522B/xx unknown
1998
- 1998-04-15 GR GR980400857T patent/GR3026654T3/el unknown

Also Published As

Publication number	Publication date
GR3026654T3 (en)	1998-07-31
ES2112329T3 (es)	1998-04-01
JPH06511244A (ja)	1994-12-15
AU2649792A (en)	1993-05-03
DE69224293D1 (de)	1998-03-05
WO1993006811A2 (en)	1993-04-15
EP0811380A3 (en)	1999-01-20
EP0811380A2 (en)	1997-12-10
EP0606318A1 (en)	1994-07-20
ATE162716T1 (de)	1998-02-15
CA2120338A1 (en)	1993-04-15
ZA927522B (en)	1993-06-16
EP0606318B1 (en)	1998-01-28
DE69224293T2 (de)	1998-07-09
JP3515107B2 (ja)	2004-04-05
WO1993006811A3 (en)	1993-06-24
US5300496A (en)	1994-04-05
NZ244569A (en)	1995-04-27

Publication	Publication Date	Title
DK0606318T3 (da)	1998-09-23	Vanadiumholdige præparater
DK524187A (da)	1987-10-06	Aminosyrechelaterede midler til udlevering til specifikke biologiske vaevssteder
IL159772A0 (en)	2004-06-20	Taxol enhancer compounds
ATE259644T1 (de)	2004-03-15	Behandlung von hämoglobin enthaltenden erythrozyten mit stickstoffoxyd
DK1195159T3 (da)	2006-10-02	Terapeutisk kombination af ascorbat med lysin og arginin til forebyggelse eller behandling af cancer
FI942160A0 (fi)	1994-05-10	Substituoituja mono- ja bipyridyylimetyylipyridoneja
MY129973A (en)	2007-05-31	Sulphonylbenzyl-substituted pyridones.
ATE70450T1 (de)	1992-01-15	Zusammensetzungen aus vanadium und peroxyd als nachahmungsmittel von insulin.
DK0851762T3 (da)	2002-08-12	Farmaceutiske kombinationspræparater, som indeholder erythropoietin og jernpræparater
DK1057826T3 (da)	2003-07-21	Substituerede dimere carboxamidforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
DE69703228D1 (de)	2000-11-09	Neue 6-Hydroxy und 6-Oxo-Androstan Verbindungen mit Kardioaktivität und pharmazeutische Präparate davon
DE3575554D1 (de)	1990-03-01	Aminosaeurederivate mit antitumoraktivitaet sowie diese derivate enthaltende zusammensetzungen.
NO994511L (no)	1999-09-17	Farmasöytiske kombinerte preparater inneholdende erythropoietin og jern-preparater
DE69519049D1 (de)	2000-11-16	Polymerisationskatalysatoren
Volpe et al.	1975	Quantitative infrared spectroscopy of CO complexes of cytochrome c oxidase, hemoglobin and myoglobin: evidence for one CO per heme
Kawanishi et al.	1985	Mechanism of electron transfer to coordinated dioxygen of oxyhemoglobins to yield peroxide and methemoglobin. Protein control of electron donation by aquopentacyanoferrate (II).
ATE199497T1 (de)	2001-03-15	Moenomycin als arzneimittel zur behandlung von magengeschwüren
TR199901367T2 (xx)	1999-10-21	4-(1-piperazinil)benzoik asit t�revleri, haz�rlanma i�lemleri ve terap�tik uygulamalar�.
Miyoshi et al.	1983	The properties and structures of Glutathione Cu (II) complexes and SOD activity
DE58905990D1 (de)	1993-12-02	Antihypertensives Kombinationspräparat.
Diemer et al.	1993	2-Acetylpyridinethiosemicarbazone bismuth complexes as therapeutic agents against helicobacter pylori
GB1525844A (en)	1978-09-20	2-carbamoyl-1,2,4,5-tetrahydro-3h-2-benzazepin-3-ones
DE3771548D1 (de)	1991-08-29	Verwendung von carbonsaeure in fuer topische anwendung vorgesehenen pharmazeutischen zubereitungen.
DE3160552D1 (en)	1983-08-11	Medicine containing a biflavanone compound
Letcher	1991	(1, 3-bis (2'-pyridylimino) isoindolinato) Ni (II) complexes of phenylcyanamido ligands: crystal structure, solution and spectroscopic properties.