DK0609961T3 - Farmaceutisk præparat med langvarig frigivelse - Google Patents

Farmaceutisk præparat med langvarig frigivelse

Info

Publication number: DK0609961T3
Authority: DK; Denmark
Prior art keywords: release pharmaceutical; prolonged; pharmaceutical preparation; active ingredient; core element
Prior art date: 1989-01-06

Application number

DK94200469T

Other languages

English (en)

Inventor

Angelo Mario Morella

Mark Christopher Fisher

Original Assignee

Faulding F H & Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-01-06

Filing date

1990-01-05

Publication date

1999-04-06

1990-01-05 Application filed by Faulding F H & Co Ltd filed Critical Faulding F H & Co Ltd

1999-04-06 Application granted granted Critical

1999-04-06 Publication of DK0609961T3 publication Critical patent/DK0609961T3/da

Links

239000000825 pharmaceutical preparation Substances 0.000 title 1
230000002035 prolonged effect Effects 0.000 title 1
239000004480 active ingredient Substances 0.000 abstract 2
238000010521 absorption reaction Methods 0.000 abstract 1
230000002378 acidificating effect Effects 0.000 abstract 1
239000011248 coating agent Substances 0.000 abstract 1
238000000576 coating method Methods 0.000 abstract 1
210000000936 intestine Anatomy 0.000 abstract 1
229960005181 morphine Drugs 0.000 abstract 1
BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Natural products O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 1
-1 morphine compound Chemical class 0.000 abstract 1
239000008188 pellet Substances 0.000 abstract 1
238000013268 sustained release Methods 0.000 abstract 1
239000012730 sustained-release form Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Organic Chemistry (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Emergency Medicine (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK94200469T 1989-01-06 1990-01-05 Farmaceutisk præparat med langvarig frigivelse DK0609961T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
AUPJ219289		1989-01-06

Publications (1)

Publication Number	Publication Date
DK0609961T3 true DK0609961T3 (da)	1999-04-06

Family

ID=3773627

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK94200469T DK0609961T3 (da)	1989-01-06	1990-01-05	Farmaceutisk præparat med langvarig frigivelse
DK90300130.3T DK0377518T3 (da)	1989-01-06	1990-01-05	Farmaceutisk præparat med langvarig frigivelse

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK90300130.3T DK0377518T3 (da)	1989-01-06	1990-01-05	Farmaceutisk præparat med langvarig frigivelse

Country Status (10)

Country	Link
EP (2)	EP0377518B1 (da)
JP (1)	JP2937376B2 (da)
AT (2)	ATE133862T1 (da)
CA (1)	CA2007181C (da)
DE (2)	DE69032445T2 (da)
DK (2)	DK0609961T3 (da)
ES (2)	ES2120562T3 (da)
GR (1)	GR3019201T3 (da)
HK (1)	HK154296A (da)
NZ (1)	NZ232029A (da)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2288117A (en) *	1994-03-01	1995-10-11	Euro Celtique Sa	Sustained release morphine
US5580578A (en) *	1992-01-27	1996-12-03	Euro-Celtique, S.A.	Controlled release formulations coated with aqueous dispersions of acrylic polymers
GB2281204A (en) *	1993-07-27	1995-03-01	Euro Celtique Sa	Sustained release morphine compositions
US5968551A (en)	1991-12-24	1999-10-19	Purdue Pharma L.P.	Orally administrable opioid formulations having extended duration of effect
US5681585A (en)	1991-12-24	1997-10-28	Euro-Celtique, S.A.	Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5478577A (en) *	1993-11-23	1995-12-26	Euroceltique, S.A.	Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
GB2284760B (en) *	1993-11-23	1998-06-24	Euro Celtique Sa	A method of preparing pharmaceutical compositions by melt pelletisation
US5286493A (en) *	1992-01-27	1994-02-15	Euroceltique, S.A.	Stabilized controlled release formulations having acrylic polymer coating
US5958459A (en) *	1991-12-24	1999-09-28	Purdue Pharma L.P.	Opioid formulations having extended controlled released
US7070806B2 (en)	1992-01-27	2006-07-04	Purdue Pharma Lp	Controlled release formulations coated with aqueous dispersions of acrylic polymers
SE9202250D0 (sv) *	1992-07-29	1992-07-29	Gacell Lab Ab	Controlled release morphine preparation
ZA937382B (en) *	1992-10-06	1994-04-29	Warner Lambert Co	Novel composition for peroral therapy of cognitionimpairment and a process therefor
SE9301057L (sv) *	1993-03-30	1994-10-01	Pharmacia Ab	Beredning med kontrollerad frisättning
NZ260408A (en)	1993-05-10	1996-05-28	Euro Celtique Sa	Controlled release preparation comprising tramadol
IL110014A (en) *	1993-07-01	1999-11-30	Euro Celtique Sa	Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en)	1993-07-01	2010-06-22	Purdue Pharma Lp	Method of treating humans with opioid formulations having extended controlled release
IL109944A (en)	1993-07-01	1998-12-06	Euro Celtique Sa	Sustained release dosage unit forms containing morphine and a method of preparing these sustained release dosage unit forms
EP0711166A1 (en) *	1993-07-22	1996-05-15	Warner-Lambert Company	Controlled release tacrine drug delivery systems and methods for preparing same
US5879705A (en) *	1993-07-27	1999-03-09	Euro-Celtique S.A.	Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
EP1442745A1 (en) *	1993-10-07	2004-08-04	Euro-Celtique	Orally administrable opioid formulations having extended duration of effect
US5891471A (en)	1993-11-23	1999-04-06	Euro-Celtique, S.A.	Pharmaceutical multiparticulates
KR100354702B1 (ko) *	1993-11-23	2002-12-28	유로-셀티크 소시에떼 아노뉨	약학조성물의제조방법및서방형조성물
US5843480A (en)	1994-03-14	1998-12-01	Euro-Celtique, S.A.	Controlled release diamorphine formulation
AT403988B (de) *	1994-05-18	1998-07-27	Lannacher Heilmittel	Festes orales retardpräparat
US5460826A (en) *	1994-06-27	1995-10-24	Alza Corporation	Morphine therapy
US6491945B1 (en) *	1994-09-16	2002-12-10	Alza Corporation	Hydrocodone therapy
GB9422154D0 (en)	1994-11-03	1994-12-21	Euro Celtique Sa	Pharmaceutical compositions and method of producing the same
US5965161A (en)	1994-11-04	1999-10-12	Euro-Celtique, S.A.	Extruded multi-particulates
US5744164A (en) *	1994-12-16	1998-04-28	Nestec S.A.	Sustained release microparticulate caffeine formulation
US5834024A (en)	1995-01-05	1998-11-10	Fh Faulding & Co. Limited	Controlled absorption diltiazem pharmaceutical formulation
GB9519363D0 (en)	1995-09-22	1995-11-22	Euro Celtique Sa	Pharmaceutical formulation
US6245351B1 (en) *	1996-03-07	2001-06-12	Takeda Chemical Industries, Ltd.	Controlled-release composition
FR2752732B1 (fr) *	1996-08-28	1998-11-20	Pf Medicament	Forme galenique a liberation prolongee de milnacipran
US6919373B1 (en)	1996-11-12	2005-07-19	Alza Corporation	Methods and devices for providing prolonged drug therapy
EP0946151B1 (en) *	1996-11-25	2006-05-10	Alza Corporation	Ascending-dose dosage form
US5948787A (en) *	1997-02-28	1999-09-07	Alza Corporation	Compositions containing opiate analgesics
US6306438B1 (en)	1997-07-02	2001-10-23	Euro-Celtique, S.A.	Stabilized sustained release tramadol formulations
US6066339A (en) *	1997-10-17	2000-05-23	Elan Corporation, Plc	Oral morphine multiparticulate formulation
TR200001942T2 (tr) *	1997-12-22	2000-11-21	Euro-Celtique, S.A.	Opioid agonist/antagonist kombinasyonlar
WO1999047128A1 (en) *	1998-03-19	1999-09-23	Bristol-Myers Squibb Company	Biphasic controlled release delivery system for high solubility pharmaceuticals and method
US6806294B2 (en)	1998-10-15	2004-10-19	Euro-Celtique S.A.	Opioid analgesic
DE19918325A1 (de)	1999-04-22	2000-10-26	Euro Celtique Sa	Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
FR2794646B1 (fr) *	1999-06-09	2001-09-21	Ethypharm Lab Prod Ethiques	Microgranules de sulfate de morphine, procede de preparation et composition les contenant
BR0013720A (pt) *	1999-09-02	2002-07-23	Nostrum Pharmaceuticals Inc	Formulação em pelota de liberação controlada
JP2003509439A (ja) *	1999-09-14	2003-03-11	スミスクライン・ビーチャム・コーポレイション	水性コーティングされたビーズレットの製法
EP2295043A1 (en)	1999-10-29	2011-03-16	Euro-Celtique S.A.	Controlled release hydrocodone formulations
US10179130B2 (en)	1999-10-29	2019-01-15	Purdue Pharma L.P.	Controlled release hydrocodone formulations
US6242003B1 (en)	2000-04-13	2001-06-05	Novartis Ag	Organic compounds
JP2002003366A (ja) *	2000-06-23	2002-01-09	Freunt Ind Co Ltd	固形薬剤用水系コーティング剤組成物
FR2811571B1 (fr)	2000-07-11	2002-10-11	Flamel Tech Sa	Composition pharmaceutique orale, permettant la liberation controlee et l'absorption prolongee d'un principe actif
US8858961B2 (en)	2000-07-14	2014-10-14	Allergan, Inc.	Compositions containing alpha-2-adrenergic agonist components
IT1318625B1 (it)	2000-07-14	2003-08-27	Roberto Valducci	Formulazioni farmaceutiche solide orali a rilascio multifasicoph-dipendente.
EP1365811A2 (en)	2000-07-14	2003-12-03	Allergan, Inc.	Compositions containing alpha-2-adrenergic agonist components
CA2416169C (en)	2000-07-14	2008-09-23	Allergan, Inc.	Compositions containing therapeutically active components having enhanced solubility
AU2002227383B2 (en)	2000-10-30	2004-07-08	Euro-Celtique S.A.	Controlled release hydrocodone formulations
US20060127474A1 (en)	2001-04-11	2006-06-15	Oskar Kalb	Pharmaceutical compositions comprising fluvastatin
UA81224C2 (uk)	2001-05-02	2007-12-25	Euro Celtic S A	Дозована форма оксикодону та її застосування
US20110104214A1 (en)	2004-04-15	2011-05-05	Purdue Pharma L.P.	Once-a-day oxycodone formulations
US6524618B1 (en)	2001-06-12	2003-02-25	Vijai Kumar	Directly compressible extended-release matrix formulation for metformin hydrochloride
US8101209B2 (en)	2001-10-09	2012-01-24	Flamel Technologies	Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
JP4732696B2 (ja)	2002-04-09	2011-07-27	フラメル・テクノロジー	活性成分の改変された放出のための、マイクロカプセルの水性懸濁液形態での経口医薬品製剤
TW200404544A (en) *	2002-06-17	2004-04-01	Kowa Co	Controlled release pharmaceutical composition
KR20060092255A (ko)	2003-09-26	2006-08-22	알자 코포레이션	고도의 약물적재를 제공하는 약물코팅제 및 그의 제조방법
EP1680098A4 (en) *	2003-11-04	2012-06-13	Supernus Pharmaceuticals Inc	DELAYED RELEASE OF POSITIVELY-LOADED PHARMACOLOGICALLY EFFECTIVE MOLECULES FROM A POLYMER-CONTAINING MATRIX WITH POLARIZED OXYGENATOMES
WO2006124890A1 (en) *	2005-05-13	2006-11-23	Alpharma, Inc.	Morphine sulphate formulations
WO2006124898A1 (en) *	2005-05-13	2006-11-23	Alpharma, Inc.	Morphine sulfate formulations
AU2006275476A1 (en) *	2005-08-01	2007-02-08	Alpharma Inc.	Alcohol resistant pharmaceutical formulations
US11311490B2 (en)	2005-08-10	2022-04-26	Add Advanced Drug Delivery Technologies Ltd.	Oral preparation with controlled release
US20070264346A1 (en) *	2006-02-16	2007-11-15	Flamel Technologies	Multimicroparticulate pharmaceutical forms for oral administration
CN104825397A (zh) *	2006-04-03	2015-08-12	伊萨·奥迪迪	含有机溶胶涂层的受控释放递送物件
US9023400B2 (en)	2006-05-24	2015-05-05	Flamel Technologies	Prolonged-release multimicroparticulate oral pharmaceutical form
FR2901478B1 (fr) *	2006-05-24	2015-06-05	Flamel Tech Sa	Forme pharmaceutique orale multimicroparticulaire a liberation prolongee
FR2946533A1 (fr)	2009-06-12	2010-12-17	Ethypharm Sa	Reduction des fluctuations plasmatiques d'opioides.
FR2951378B1 (fr) *	2009-10-16	2012-06-01	Flamel Tech Sa	Forme pharmaceutique orale solide anti-mesusage et dotee d'un profil specifique de liberation modifiee
RU2596787C2 (ru)	2010-07-09	2016-09-10	БиЭйчВи ФАРМА, ИНК.	Комбинированная система доставки с немедленным/замедленным высвобождением для лекарственных средств с коротким периодом полувыведения, в том числе для ремоглифлозина
US20120251588A1 (en) *	2011-03-30	2012-10-04	Miyuki Fukasawa	Coating Composition, Solid Preparation Coated Therewith, and Method for Preparing Solid Preparation
EP2606879A1 (en)	2011-12-21	2013-06-26	Hexal AG	Multiple unit pellet tablet formulation comprising an opioid
CA2910865C (en)	2014-07-15	2016-11-29	Isa Odidi	Compositions and methods for reducing overdose
US20170182070A1 (en) *	2014-10-08	2017-06-29	Mayne Pharma International Pty Ltd.	Controlled Release Doxycycline
US20170042806A1 (en)	2015-04-29	2017-02-16	Dexcel Pharma Technologies Ltd.	Orally disintegrating compositions
US10835499B2 (en)	2015-12-30	2020-11-17	Corium, Inc.	Systems and methods for long term transdermal administration
US10076494B2 (en)	2016-06-16	2018-09-18	Dexcel Pharma Technologies Ltd.	Stable orally disintegrating pharmaceutical compositions
CN109922796B (zh)	2016-06-23	2023-04-07	考里安有限责任公司	具有亲水和疏水域的粘合剂基质和治疗剂
JP7071330B2 (ja) *	2016-07-27	2022-05-18	コリウム，インコーポレイテッド	炭酸水素ナトリウムのｉｎｓｉｔｕ変換で促進されたアミン薬物の経皮送達
US10765635B2 (en)	2018-02-06	2020-09-08	Nano Pharmaceutical Laboratories Llc	Multiparticulate including pharmaceutical or probiotic active ingredients for delivery via a shelf stable liquid dosage form

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8414220D0 (en) *	1984-06-04	1984-07-11	Sterwin Ag	Medicaments in unit dose form
GB8514665D0 (en) *	1985-06-11	1985-07-10	Eroceltique Sa	Oral pharmaceutical composition
SE460947B (sv) *	1986-08-26	1989-12-11	Lejus Medical Ab	En multiple-unit-dos komposition av l-dopa
EP0327295A3 (en) *	1988-02-01	1989-09-06	F.H. FAULDING & CO. LTD.	Tetracycline dosage form

1990
- 1990-01-04 CA CA002007181A patent/CA2007181C/en not_active Expired - Lifetime
- 1990-01-05 EP EP90300130A patent/EP0377518B1/en not_active Expired - Lifetime
- 1990-01-05 DE DE69032445T patent/DE69032445T2/de not_active Expired - Lifetime
- 1990-01-05 DK DK94200469T patent/DK0609961T3/da active
- 1990-01-05 ES ES94200469T patent/ES2120562T3/es not_active Expired - Lifetime
- 1990-01-05 NZ NZ232029A patent/NZ232029A/en unknown
- 1990-01-05 EP EP94200469A patent/EP0609961B1/en not_active Expired - Lifetime
- 1990-01-05 AT AT90300130T patent/ATE133862T1/de not_active IP Right Cessation
- 1990-01-05 ES ES90300130T patent/ES2085886T3/es not_active Expired - Lifetime
- 1990-01-05 AT AT94200469T patent/ATE167629T1/de not_active IP Right Cessation
- 1990-01-05 DK DK90300130.3T patent/DK0377518T3/da active
- 1990-01-05 DE DE69025208T patent/DE69025208T2/de not_active Expired - Lifetime
- 1990-01-06 JP JP2000903A patent/JP2937376B2/ja not_active Expired - Lifetime
1996
- 1996-03-05 GR GR960400605T patent/GR3019201T3/el unknown
- 1996-08-08 HK HK154296A patent/HK154296A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2120562T3 (es)	1998-11-01
ATE133862T1 (de)	1996-02-15
GR3019201T3 (en)	1996-06-30
DE69025208T2 (de)	1996-06-13
JP2937376B2 (ja)	1999-08-23
NZ232029A (en)	1992-04-28
CA2007181A1 (en)	1990-07-06
EP0377518A2 (en)	1990-07-11
AU4773290A (en)	1990-07-12
DE69032445D1 (de)	1998-07-30
CA2007181C (en)	1998-11-24
EP0377518B1 (en)	1996-02-07
EP0609961B1 (en)	1998-06-24
ATE167629T1 (de)	1998-07-15
EP0377518A3 (en)	1990-10-24
DE69025208D1 (de)	1996-03-21
JPH032114A (ja)	1991-01-08
EP0609961A1 (en)	1994-08-10
HK154296A (en)	1996-08-16
ES2085886T3 (es)	1996-06-16
DK0377518T3 (da)	1996-06-24
DE69032445T2 (de)	1999-02-18
AU617573B2 (en)	1991-11-28

Publication	Publication Date	Title
DK0377518T3 (da)	1996-06-24	Farmaceutisk præparat med langvarig frigivelse
DK0652747T3 (da)	1999-09-20	Morfinpræparat med reguleret frigivelse
ATE67933T1 (de)	1991-10-15	Hydromorphon-zusammensetzung mit gesteuerter wirkstofffreisetzung.
EP0377517A3 (en)	1990-10-24	Theophylline dosage form
DK555089D0 (da)	1989-11-07	Farmaceutiske praeparater indeholdende n-(3,4-dimethoxycinnamoyl)anthranilsyre
ES2062417T3 (es)	1994-12-16	Composiciones farmaceuticas de cimetidina.
DK293087D0 (da)	1987-06-09	Fast dihydrocodeinpraeparat med reguleret afgivelse
ATE154239T1 (de)	1997-06-15	Sphäroidische arzneimittelformulierung
ES2172239T3 (es)	2002-09-16	Sistema osmotico de liberacion de farmacos.
EP0974350A4 (en)	2000-01-26	EXTERNAL CONTAINING TRANILAST AND METHOD FOR THE PRODUCTION THEREOF
ATE198152T1 (de)	2001-01-15	Oral anzuwendende arzneizubereitung mit verzögerter wirkstoffabgabe
DK164441C (da)	1992-11-09	Anvendelse af et piperidinderivat til fremstilling af et farmaceutisk praeparat til behandling af smertetilstande
CA2083385A1 (en)	1991-11-25	Sustained Release Suppository
EP0813409A4 (en)	1999-01-07	TREATMENT OF DISEASES CAUSED BY THE CYTOKIN GROWTH FACTOR
HU0102987D0 (en)	2001-09-28	Pharmaceutical composition for treating parkinson's disease comprising astrocyte function-improving agent as active ingredient
NO164958C (no)	1990-12-05	Fremgangsmaate for fremstilling av dipyridamol-preparater med ph-uavhengig, regulert frigjoering.