DK0620733T3 - Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf - Google Patents

Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf

Info

Publication number: DK0620733T3
Authority: DK; Denmark
Prior art keywords: pct; nifedipine; pharmaceutical compositions; preparation; compositions containing
Prior art date: 1992-01-13

Application number

DK93901850T

Other languages

English (en)

Inventor

David Trigger

Original Assignee

Ethical Pharmaceuticals U K Li

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-13

Filing date

1993-01-12

Publication date

2000-07-24

1993-01-12 Application filed by Ethical Pharmaceuticals U K Li filed Critical Ethical Pharmaceuticals U K Li

2000-07-24 Application granted granted Critical

2000-07-24 Publication of DK0620733T3 publication Critical patent/DK0620733T3/da

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Hydrogenated Pyridines (AREA)
Saccharide Compounds (AREA)

DK93901850T 1992-01-13 1993-01-12 Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf DK0620733T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929200607A GB9200607D0 (en)	1992-01-13	1992-01-13	Pharmaceutical compositions containing nifedipine and process for the preparation thereof
PCT/GB1993/000055 WO1993013773A1 (en)	1992-01-13	1993-01-12	Pharmaceutical compositions containing nifedipine and process for the preparation thereof

Publications (1)

Publication Number	Publication Date
DK0620733T3 true DK0620733T3 (da)	2000-07-24

Family

ID=10708487

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK93901850T DK0620733T3 (da)	1992-01-13	1993-01-12	Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf
DK083794A DK83794A (da)	1992-01-13	1994-07-11	Farmaceutiske præparater indeholdende nifedipin og fremgangsmåde til fremstilling heraf

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK083794A DK83794A (da)	1992-01-13	1994-07-11	Farmaceutiske præparater indeholdende nifedipin og fremgangsmåde til fremstilling heraf

Country Status (24)

Country	Link
US (1)	US5594013A (da)
EP (1)	EP0620733B1 (da)
JP (1)	JPH07503003A (da)
AT (1)	ATE191144T1 (da)
AU (1)	AU659529B2 (da)
CA (1)	CA2126864A1 (da)
DE (2)	DE4390075T1 (da)
DK (2)	DK0620733T3 (da)
ES (1)	ES2146227T3 (da)
FI (1)	FI943316L (da)
GB (2)	GB9200607D0 (da)
HU (2)	HU219338B (da)
IS (1)	IS1620B (da)
MY (1)	MY110660A (da)
NL (1)	NL9320021A (da)
NO (1)	NO305223B1 (da)
NZ (1)	NZ246374A (da)
PH (1)	PH30985A (da)
PL (1)	PL170935B1 (da)
PT (1)	PT620733E (da)
RU (1)	RU2106139C1 (da)
SE (1)	SE9402457L (da)
WO (1)	WO1993013773A1 (da)
ZA (1)	ZA93195B (da)

Families Citing this family (29)

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WO1994005262A1 (en) *	1992-09-10	1994-03-17	F.H. Faulding & Co. Limited	Sustained release matrix composition
US5773025A (en)	1993-09-09	1998-06-30	Edward Mendell Co., Inc.	Sustained release heterodisperse hydrogel systems--amorphous drugs
US5455046A (en) *	1993-09-09	1995-10-03	Edward Mendell Co., Inc.	Sustained release heterodisperse hydrogel systems for insoluble drugs
US5871776A (en) *	1995-01-31	1999-02-16	Mehta; Atul M.	Controlled-release nifedipine
WO1997008950A1 (en) *	1995-09-07	1997-03-13	Fuisz Technologies, Ltd.	System for rendering substantially non-dissoluble bio-affecting agents bio-available
CO4771151A1 (es) *	1996-01-19	1999-04-30	Rachitzky Falicman Pablo Alberto	Procedimiento para la elaboracion de una preparacion farmace utica que contiene nifedipina y la preparacion farmaceutica obtenida mediante el mismo
JP3148256B2 (ja) *	1996-07-08	2001-03-19	エドワードメンデルカンパニー．，インコーポレーテッド	高用量難溶性薬物用持続放出マトリックス
IT1284604B1 (it) *	1996-09-27	1998-05-21	Roberto Valducci	Composizioni farmaceutiche a rilascio controllato per somministrazione orale contenenti nifedipina come sostanza attiva
US5922352A (en) *	1997-01-31	1999-07-13	Andrx Pharmaceuticals, Inc.	Once daily calcium channel blocker tablet having a delayed release core
US5837379A (en) *	1997-01-31	1998-11-17	Andrx Pharmaceuticals, Inc.	Once daily pharmaceutical tablet having a unitary core
US6056977A (en)	1997-10-15	2000-05-02	Edward Mendell Co., Inc.	Once-a-day controlled release sulfonylurea formulation
US6485748B1 (en)	1997-12-12	2002-11-26	Andrx Pharmaceuticals, Inc.	Once daily pharmaceutical tablet having a unitary core
US6264872B1 (en)	1997-12-30	2001-07-24	Kimberly-Clark Worldwide, Inc.	Method of forming thin, embossed, textured barrier films
US6969529B2 (en)	2000-09-21	2005-11-29	Elan Pharma International Ltd.	Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers
US6706283B1 (en)	1999-02-10	2004-03-16	Pfizer Inc	Controlled release by extrusion of solid amorphous dispersions of drugs
US6168806B1 (en)	1999-03-05	2001-01-02	Fang-Yu Lee	Orally administrable nifedipine pellet and process for the preparation thereof
EP1341521B1 (en) *	2000-11-20	2009-01-07	Elan Pharma International Limited	Nanoparticulate compositions comprising a drug and copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers
SE0100200D0 (sv) *	2001-01-24	2001-01-24	Astrazeneca Ab	New film coating
US20040253312A1 (en) *	2001-09-28	2004-12-16	Sowden Harry S.	Immediate release dosage form comprising shell having openings therein
ES2233876T3 (es) *	2001-12-19	2005-06-16	Astrazeneca Ab	Nuevo recubrimiento de pelicula que contiene un copolimero acrilato de etilo/metacrilato de metilo y poli (acetato de vinilo).
US6620900B2 (en) *	2002-02-07	2003-09-16	Isp Investments Inc.	Proliferous copolymer of vinyl pyrrolidone and vinyl acetate
MY140561A (en)	2002-02-20	2009-12-31	Nycomed Gmbh	Dosage form containing pde 4 inhibitor as active ingredient
RU2220725C1 (ru) *	2002-08-01	2004-01-10	Закрытое акционерное общество "Брынцалов-А"	Антиангинальное, антигипертензивное средство
EP1539270A1 (en) *	2002-09-18	2005-06-15	Medtronic Vascular, Inc.	Controllable drug releasing gradient coatings for medical devices
AU2006232896A1 (en) *	2005-04-06	2006-10-12	Mallinckrodt Inc.	Matrix-based pulse release pharmaceutical formulation
WO2007106111A2 (en) *	2005-07-01	2007-09-20	Elan Pharma International Limited	Nanoparticulate and controlled release compositions comprising nilvadipine
JP5351490B2 (ja) *	2007-10-25	2013-11-27	バイエル薬品株式会社	ニフェジピン含有有核錠剤およびその製法
RU2629843C1 (ru) *	2016-05-24	2017-09-04	федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет)	Способ получения мази нифедипина (варианты)
CN115844845B (zh) *	2022-08-29	2025-03-14	迪沙药业集团有限公司	一种硝苯地平缓释制剂及制备方法

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DE2400819C2 (de) *	1974-01-09	1982-04-22	Bayer Ag, 5090 Leverkusen	Verfahren zur Herstellung fester Zubereitungen von schwerlöslichen Arzneimittelwirkstoffen in feinster Verteilung
GB1579818A (en) *	1977-06-07	1980-11-26	Yamanouchi Pharma Co Ltd	Nifedipine-containing solid preparation composition
EP0001247A1 (en) *	1977-09-14	1979-04-04	Kanebo, Ltd.	Pharmaceutical preparation containing nifedipine and a method for producing the same.
CA1146866A (en) *	1979-07-05	1983-05-24	Yamanouchi Pharmaceutical Co. Ltd.	Process for the production of sustained release pharmaceutical composition of solid medical material
DE3172915D1 (en) *	1980-09-05	1985-12-19	Argus Chem	Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins
DE3033919A1 (de) *	1980-09-09	1982-04-22	Bayer Ag, 5090 Leverkusen	Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung
JPS5846019A (ja) *	1981-09-14	1983-03-17	Kanebo Ltd	持続性ニフエジピン製剤
EP0078430B2 (de) *	1981-10-29	1993-02-10	Bayer Ag	Verfahren zur Herstellung von festen, schnellfreisetzenden Arzneizubereitungen mit Dihydropyridinen
EP0159604B1 (en) *	1984-04-09	1990-11-07	Toyo Boseki Kabushiki Kaisha	Sustained-release preparation applicable to mucous membrane in oral cavity
DE3424553A1 (de) *	1984-07-04	1986-01-09	Bayer Ag, 5090 Leverkusen	Feste arzneizubereitungen mit dihydropyridinen und verfahren zu ihrer herstellung
IT1178511B (it) *	1984-09-14	1987-09-09	Pharmatec Spa	Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio
DE3438830A1 (de) *	1984-10-23	1986-04-30	Rentschler Arzneimittel	Nifedipin enthaltende darreichungsform und verfahren zu ihrer herstellung
FR2579510B1 (fr) *	1985-03-29	1989-12-15	Demler Sa Ets	Table vibrante pour la fabrication de produits en beton
FR2585174B1 (fr) *	1985-07-16	1987-11-27	Eurofarad	Procede de fabrication d'un composant capacitif multicouche a dielectrique ceramique du type cordierite, et composant ainsi obtenu
IE63321B1 (en) *	1986-02-03	1995-04-05	Elan Corp Plc	Drug delivery system
SE8601624D0 (sv) *	1986-04-11	1986-04-11	Haessle Ab	New pharmaceutical preparations
GB8613689D0 (en) *	1986-06-05	1986-07-09	Euro Celtique Sa	Pharmaceutical composition
US4970075A (en) *	1986-07-18	1990-11-13	Euroceltique, S.A.	Controlled release bases for pharmaceuticals
IE59540B1 (en) *	1987-01-09	1994-03-09	Elan Corp	Sustained release capsule or tablet formulation
US4968508A (en) *	1987-02-27	1990-11-06	Eli Lilly And Company	Sustained release matrix
GB8722306D0 (en) *	1987-09-22	1987-10-28	Aps Research Ltd	Sustained-release formulation
GB8903328D0 (en) *	1989-02-14	1989-04-05	Ethical Pharma Ltd	Nifedipine-containing pharmaceutical compositions and process for the preparation thereof
ES2077023T3 (es) *	1989-03-10	1995-11-16	Yamanouchi Pharma Co Ltd	Material de recubrimiento que controla la liberacion de un medicamento para formulaciones de actividad prolongada.
HU203041B (en) *	1989-03-14	1991-05-28	Egyt Gyogyszervegyeszeti Gyar	Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin
JPH0729926B2 (ja) *	1989-07-25	1995-04-05	大塚製薬株式会社	易吸収性製剤用組成物

1992
- 1992-01-13 GB GB929200607A patent/GB9200607D0/en active Pending
1993
- 1993-01-11 IS IS3966A patent/IS1620B/is unknown
- 1993-01-12 CA CA002126864A patent/CA2126864A1/en not_active Abandoned
- 1993-01-12 ZA ZA93195A patent/ZA93195B/xx unknown
- 1993-01-12 ES ES93901850T patent/ES2146227T3/es not_active Expired - Lifetime
- 1993-01-12 FI FI943316A patent/FI943316L/fi unknown
- 1993-01-12 JP JP5512264A patent/JPH07503003A/ja active Pending
- 1993-01-12 NZ NZ246374A patent/NZ246374A/en unknown
- 1993-01-12 EP EP93901850A patent/EP0620733B1/en not_active Expired - Lifetime
- 1993-01-12 US US08/256,398 patent/US5594013A/en not_active Expired - Lifetime
- 1993-01-12 PL PL93300638A patent/PL170935B1/pl unknown
- 1993-01-12 DE DE4390075T patent/DE4390075T1/de not_active Withdrawn
- 1993-01-12 AT AT93901850T patent/ATE191144T1/de not_active IP Right Cessation
- 1993-01-12 DE DE69328245T patent/DE69328245T2/de not_active Expired - Fee Related
- 1993-01-12 GB GB9413101A patent/GB2277872B/en not_active Expired - Fee Related
- 1993-01-12 AU AU32636/93A patent/AU659529B2/en not_active Ceased
- 1993-01-12 NL NL9320021A patent/NL9320021A/nl not_active Application Discontinuation
- 1993-01-12 MY MYPI93000048A patent/MY110660A/en unknown
- 1993-01-12 DK DK93901850T patent/DK0620733T3/da active
- 1993-01-12 PH PH45554A patent/PH30985A/en unknown
- 1993-01-12 RU RU94035739A patent/RU2106139C1/ru active
- 1993-01-12 WO PCT/GB1993/000055 patent/WO1993013773A1/en not_active Ceased
- 1993-01-12 HU HU9401850A patent/HU219338B/hu not_active IP Right Cessation
- 1993-01-12 PT PT93901850T patent/PT620733E/pt unknown
1994
- 1994-07-11 DK DK083794A patent/DK83794A/da not_active Application Discontinuation
- 1994-07-12 SE SE9402457A patent/SE9402457L/ not_active Application Discontinuation
- 1994-07-12 NO NO942622A patent/NO305223B1/no unknown
1995
- 1995-01-11 HU HU95P/P00065P patent/HU210539A9/hu unknown

Also Published As

Publication number	Publication date
ES2146227T3 (es)	2000-08-01
GB9413101D0 (en)	1994-08-31
GB9200607D0 (en)	1992-03-11
DE69328245D1 (de)	2000-05-04
GB2277872B (en)	1995-10-04
MY110660A (en)	1999-01-30
NO942622D0 (no)	1994-07-12
PH30985A (en)	1997-12-23
HU219338B (en)	2001-03-28
HUT67426A (en)	1995-04-28
JPH07503003A (ja)	1995-03-30
EP0620733A1 (en)	1994-10-26
DE69328245T2 (de)	2000-10-12
PL300638A1 (en)	1994-03-21
NL9320021A (nl)	1995-06-01
SE9402457D0 (sv)	1994-07-12
NO305223B1 (no)	1999-04-26
DK83794A (da)	1994-07-11
RU94035739A (ru)	1996-09-20
WO1993013773A1 (en)	1993-07-22
ZA93195B (en)	1993-08-16
CA2126864A1 (en)	1993-07-22
PL170935B1 (pl)	1997-02-28
PT620733E (pt)	2000-08-31
NO942622L (no)	1994-07-12
EP0620733B1 (en)	2000-03-29
IS3966A (is)	1993-07-14
IS1620B (is)	1996-10-18
US5594013A (en)	1997-01-14
AU659529B2 (en)	1995-05-18
NZ246374A (en)	1995-07-26
DE4390075T1 (de)	1994-12-01
HU210539A9 (en)	1995-05-29
ATE191144T1 (de)	2000-04-15
HU9401850D0 (en)	1994-09-28
FI943316A0 (fi)	1994-07-12
GB2277872A (en)	1994-11-16
FI943316A7 (fi)	1994-07-12
AU3263693A (en)	1993-08-03
FI943316L (fi)	1994-07-12
SE9402457L (sv)	1994-09-12
RU2106139C1 (ru)	1998-03-10

Publication	Publication Date	Title
DK0620733T3 (da)	2000-07-24	Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf
AU635021B2 (en)	1993-03-11	Extended release pharmaceutical formulations
ATE121745T1 (de)	1995-05-15	Rechtsdrehendes enantiomer von alpha-(4,5,6,7- tetrahydrothieno(3,2-c>pyrid-5-yl)(2- chlorphenyl)methylacetat, verfahren zu seiner herstellung und dieses enthaltende pharmazeutische zubereitungen.
ES2059408T3 (es)	1994-11-16	Un proceso para la preparacion de un compuesto.
DE3860618D1 (de)	1990-10-25	Filmtraeger und verfahren zu seiner herstellung.
ATE208734T1 (de)	2001-11-15	Verfahren zum markieren von gegenständen sowie nach diesem verfahren markierte gegenstände
ATE153022T1 (de)	1997-05-15	3',5'-ditertbutyl-4'-hydroxyflavone, verfahren zu ihrer herstellung und pharmazeutische zusammensetzung mit antioxidations- und antivasokonstriktionsaktivität
UA19285A (uk)	1997-12-25	Спосіб одержаhhя таблеток hіфедіпіhу
DK0626843T3 (da)	1997-10-27	Anvendelse af polyvinylpyrrolidon til nedsættelse af orale bakteriers adhærens
ATE150735T1 (de)	1997-04-15	Lagerstabil verkapseltes natriumpercarbonat und verfahren zu seiner herstellung
GEP19981357B (en)	1998-08-25	New Adenozine Derivatives, Prepatation Methods and Pharmaceutical Composit¬i¬ons Containing Them
DE3786769D1 (de)	1993-09-02	Hexagonale imideinheiten enthaltendes random-copolymer, verfahren zu dessen herstellung und substrat einer optischen platte, hergestellt aus diesem random-copolymer.
DK0701449T3 (da)	2003-11-10	Fremgangsmåde til fremstilling af en oral fast dosisform indeholdende diclofenac
DK0511223T3 (da)	1995-07-10	Overtræksmasse, fremgangsmåde til fremstilling deraf samt anvendelse deraf
DK0689441T3 (da)	2001-07-30	Farmaceutisk præparat i form af et kit omfattende prostaglandin E1
DE69215511D1 (de)	1997-01-09	Gem-diphosphonsäure-nitrosocarbamoylderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zubereitungen
MX9207007A (es)	1994-06-30	Composicion de revestimiento a base de agua, substrato revestido con la misma y proceso para revestir dicho substrato.
ATE98625T1 (de)	1994-01-15	Individuelle partikelkristalle in alpha-form von tetrakis(3-(3,5-di-t-butyl-4hydroxyphenyl)propionyloxy>methan und verfahren zu seiner herstellung.
KR830004254A (ko)	1983-07-09	니코틴 아미드 유도체, 이의 제법 및 의약 조성물