DK0628558T3 - Fremgangsmåde til syntese af 9-(2-hydroxyethoxymethyl)-guanin - Google Patents

Fremgangsmåde til syntese af 9-(2-hydroxyethoxymethyl)-guanin

Info

Publication number: DK0628558T3
Authority: DK; Denmark
Prior art keywords: guanine; synthesis; hydroxyethoxymethyl; acyclovir; subject
Prior art date: 1993-06-14

Application number

DK94108426T

Other languages

English (en)

Inventor

Tiberio Bruzzese

Giuseppe Guazzi

Marco Rognoni

Giuliano Marcon

Original Assignee

Solchem Italiana Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-14

Filing date

1994-06-01

Publication date

1999-02-08

1994-06-01 Application filed by Solchem Italiana Spa filed Critical Solchem Italiana Spa

1999-02-08 Application granted granted Critical

1999-02-08 Publication of DK0628558T3 publication Critical patent/DK0628558T3/da

Links

MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 title abstract 3
230000015572 biosynthetic process Effects 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
238000003786 synthesis reaction Methods 0.000 title abstract 2
UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 abstract 2
229960004150 aciclovir Drugs 0.000 abstract 1
238000002955 isolation Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK94108426T 1993-06-14 1994-06-01 Fremgangsmåde til syntese af 9-(2-hydroxyethoxymethyl)-guanin DK0628558T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT93MI001264A IT1264599B1 (it)	1993-06-14	1993-06-14	Processo per la sintesi della 9-(2-idrossietossimetil)- guanina

Publications (1)

Publication Number	Publication Date
DK0628558T3 true DK0628558T3 (da)	1999-02-08

Family

ID=11366388

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94108426T DK0628558T3 (da)	1993-06-14	1994-06-01	Fremgangsmåde til syntese af 9-(2-hydroxyethoxymethyl)-guanin

Country Status (7)

Country	Link
US (1)	US5496945A (da)
EP (1)	EP0628558B1 (da)
AT (1)	ATE165096T1 (da)
DE (1)	DE69409578T2 (da)
DK (1)	DK0628558T3 (da)
ES (1)	ES2117172T3 (da)
IT (1)	IT1264599B1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1276126B1 (it) *	1995-11-14	1997-10-27	Archimica Spa	Procedimento per la preparazine di 9-((2-idrossietossi)metil) guanina
CN103601768B (zh) *	2013-11-13	2015-09-30	齐鲁天和惠世制药有限公司	一种阿米卡星的制备方法
CN107903268A (zh) *	2017-11-16	2018-04-13	湖北省宏源药业科技股份有限公司	一种阿昔洛韦的提纯方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1523865A (en) *	1974-09-02	1978-09-06	Wellcome Found	Purine compunds and salts thereof
US4146715A (en) *	1975-08-27	1979-03-27	Burroughs Wellcome Co.	2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines
DK135489D0 (da) *	1989-03-20	1989-03-20	Gea Farmaceutisk Fabrik As	Fremgangsmaade til fremstilling af 9-substituerede guaninderivater og mellemprodukter til brug ved fremgangsmaaden
JP3225545B2 (ja) *	1991-09-18	2001-11-05	味の素株式会社	非環状ヌクレオシド類の製造法

1993
- 1993-06-14 IT IT93MI001264A patent/IT1264599B1/it active IP Right Grant
1994
- 1994-06-01 DK DK94108426T patent/DK0628558T3/da active
- 1994-06-01 EP EP94108426A patent/EP0628558B1/en not_active Expired - Lifetime
- 1994-06-01 AT AT94108426T patent/ATE165096T1/de not_active IP Right Cessation
- 1994-06-01 DE DE69409578T patent/DE69409578T2/de not_active Expired - Fee Related
- 1994-06-01 ES ES94108426T patent/ES2117172T3/es not_active Expired - Lifetime
- 1994-06-13 US US08/261,053 patent/US5496945A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0628558B1 (en)	1998-04-15
ITMI931264A1 (it)	1994-12-14
ITMI931264A0 (it)	1993-06-14
DE69409578D1 (de)	1998-05-20
ES2117172T3 (es)	1998-08-01
US5496945A (en)	1996-03-05
ATE165096T1 (de)	1998-05-15
IT1264599B1 (it)	1996-10-04
DE69409578T2 (de)	1998-11-19
EP0628558A1 (en)	1994-12-14

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