DK0637248T3 - Farmaceutisk sammensætning indeholdende et cyclosporinderivat - Google Patents

Farmaceutisk sammensætning indeholdende et cyclosporinderivat

Info

Publication number: DK0637248T3
Authority: DK; Denmark
Prior art keywords: pharmaceutical composition; composition containing; cyclosporine derivative; composition; microemulstion
Prior art date: 1992-04-22

Application number

DK93911768T

Other languages

English (en)

Inventor

Armin Meinzer

Friedrich Richter

Jacky Francis Vonderscher

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-22

Filing date

1993-04-20

Publication date

2002-10-28

1993-04-20 Application filed by Novartis Ag filed Critical Novartis Ag

2002-10-28 Application granted granted Critical

2002-10-28 Publication of DK0637248T3 publication Critical patent/DK0637248T3/da

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
239000000203 mixture Substances 0.000 abstract 2
206010048723 Multiple-drug resistance Diseases 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
229960000074 biopharmaceutical Drugs 0.000 abstract 1
229960001265 ciclosporin Drugs 0.000 abstract 1
239000004530 micro-emulsion Substances 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1
208000011580 syndromic disease Diseases 0.000 abstract 1
235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
239000008158 vegetable oil Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

DK93911768T 1992-04-22 1993-04-20 Farmaceutisk sammensætning indeholdende et cyclosporinderivat DK0637248T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929208712A GB9208712D0 (en)	1992-04-22	1992-04-22	Pharmaceutical compositions containing cyclosporin derivates
PCT/EP1993/000955 WO1993020833A1 (en)	1992-04-22	1993-04-20	Pharmaceutical composition containing cyclosporin derivative

Publications (1)

Publication Number	Publication Date
DK0637248T3 true DK0637248T3 (da)	2002-10-28

Family

ID=10714386

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93911768T DK0637248T3 (da)	1992-04-22	1993-04-20	Farmaceutisk sammensætning indeholdende et cyclosporinderivat

Country Status (22)

Country	Link
EP (1)	EP0637248B1 (da)
JP (1)	JP2818298B2 (da)
KR (2)	KR950701227A (da)
AT (1)	ATE219940T1 (da)
AU (1)	AU672793B2 (da)
CA (1)	CA2132740C (da)
CY (1)	CY2399B1 (da)
CZ (1)	CZ287359B6 (da)
DE (1)	DE69332078T2 (da)
DK (1)	DK0637248T3 (da)
ES (1)	ES2179052T3 (da)
FI (1)	FI111130B (da)
GB (1)	GB9208712D0 (da)
HU (1)	HU218279B (da)
NO (1)	NO315075B1 (da)
NZ (1)	NZ252681A (da)
PT (1)	PT637248E (da)
RU (1)	RU2126263C1 (da)
SG (1)	SG50692A1 (da)
SK (1)	SK282745B6 (da)
UA (1)	UA34454C2 (da)
WO (1)	WO1993020833A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6007840A (en) *	1988-09-16	1999-12-28	Novartis Ag	Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) *	1988-09-16	1998-08-17	장 크라메르, 한스 루돌프 하우스	사이클로스포린을 함유하는 약학조성물
US6262022B1 (en)	1992-06-25	2001-07-17	Novartis Ag	Pharmaceutical compositions containing cyclosporin as the active agent
SG45449A1 (en) *	1992-05-13	1998-01-16	Sandoz Ltd	Ophthalmic compositions
DK0589843T3 (da) *	1992-09-25	2002-04-02	Novartis Ag	Cyclosporinholdige farmaceutiske præparater
CH686761A5 (de) *	1993-05-27	1996-06-28	Sandoz Ag	Galenische Formulierungen.
GB2278780B (en) *	1993-05-27	1998-10-14	Sandoz Ltd	Macrolide formulations
GB2315216B (en) *	1993-10-05	1998-10-14	Ciba Geigy Ag	Microemulsion preconcentrates comprising FK506 or 33-epi-chloro-33-desoxy-ascomycin
ES2177652T3 (es)	1994-11-03	2002-12-16	Novartis Ag	Nuevas formas de preparacion de ciclosporina para la aplicacion oral con composicion simple y alta biodisponibilidad, y procedimiento para su obtencion.
HU215966B (hu) *	1994-11-21	1999-07-28	BIOGAL Gyógyszergyár Rt.	Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
US5962019A (en) *	1995-08-25	1999-10-05	Sangstat Medical Corporation	Oral cyclosporin formulations
US5766629A (en)	1995-08-25	1998-06-16	Sangstat Medical Corporation	Oral cyclosporin formulations
DE19544507B4 (de)	1995-11-29	2007-11-15	Novartis Ag	Cyclosporin enthaltende Präparate
GB9601120D0 (en) *	1996-01-19	1996-03-20	Sandoz Ltd	Organic compounds
HU223054B1 (hu) *	1997-03-25	2004-03-01	BIOGAL Gyógyszergyár Rt.	Tisztítási eljárás nagytisztaságú ciklosporin A előállítására
CN1208047C (zh) *	1997-07-29	2005-06-29	法玛西雅厄普约翰美国公司	亲脂性化合物的自体乳化剂
NZ502566A (en) *	1997-07-29	2002-03-28	Upjohn Co	Pharmaceutical composition for acidic lipophilic compounds in a form of a self-emulsifying formulation containing a pyranone and a basic amine
US6008191A (en) *	1997-09-08	1999-12-28	Panacea Biotec Limited	Pharmaceutical compositions containing cyclosporin
US6187747B1 (en)	1997-09-08	2001-02-13	Panacea Biotech Limited	Pharmaceutical composition comprising cyclosporin
US6346511B1 (en)	1997-09-08	2002-02-12	Panacea Biotec Limited	Pharmaceutical composition comprising cyclosporin
KR20010041623A (ko) *	1998-03-05	2001-05-25	니뽄 신야쿠 가부시키가이샤	흡입 투여용 지방 유제
US6294192B1 (en) *	1999-02-26	2001-09-25	Lipocine, Inc.	Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
TNSN03139A1 (fr)	2001-06-21	2005-12-23	Pfizer Prod Inc	Formulations auto-emulsionnables d'inhibiteurs de la proteine de transfert d'ester de cholesteryle
EP2116228A1 (en) *	2001-10-19	2009-11-11	Isotechnika Inc.	Novel cyclosporin analog microemulsion preconcentrates
US6828301B2 (en)	2002-02-07	2004-12-07	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions for hepatitis C viral protease inhibitors
RU2294959C2 (ru) *	2005-05-18	2007-03-10	Общество с ограниченной ответственностью "Карат" (ООО "Карат")	Способ получения акарицидно-моющего средства для борьбы с клещами
RU2293763C2 (ru) *	2005-05-18	2007-02-20	Государственное учреждение Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова Российской академии медицинских наук (ГУ НИИВС им. И.И. Мечникова РАМН)	Способ получения акарицидно-моющего средства для борьбы с клещами
RU2320365C2 (ru) *	2005-09-15	2008-03-27	Григорьев Лев Викторович	Фармацевтическая композиция
EP2204167A1 (en) *	2009-01-05	2010-07-07	Azad Pharma AG	Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules
WO2011005646A2 (en)	2009-07-07	2011-01-13	Boehringer Ingelheim International Gmbh	Pharmaceutical composition for a hepatitis c viral protease inhibitor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE445174B (sv) *	1978-03-07	1986-06-09	Sandoz Ag	Farmaceutisk komposition innehallande en cyklosporin och en berarsubstans
ES2059558T3 (es) *	1987-06-17	1994-11-16	Sandoz Ag	Ciclosporins y su uso como productos farmaceuticos.
CZ279654B6 (cs) *	1987-12-21	1995-05-17	Sandoz Ag	Způsob výroby cyklosporinu A
KR0148748B1 (ko) *	1988-09-16	1998-08-17	장 크라메르, 한스 루돌프 하우스	사이클로스포린을 함유하는 약학조성물

1992
- 1992-04-22 GB GB929208712A patent/GB9208712D0/en active Pending
1993
- 1993-04-20 PT PT93911768T patent/PT637248E/pt unknown
- 1993-04-20 WO PCT/EP1993/000955 patent/WO1993020833A1/en not_active Ceased
- 1993-04-20 SG SG1996008843A patent/SG50692A1/en unknown
- 1993-04-20 UA UA94105950A patent/UA34454C2/uk unknown
- 1993-04-20 DK DK93911768T patent/DK0637248T3/da active
- 1993-04-20 EP EP93911768A patent/EP0637248B1/en not_active Expired - Lifetime
- 1993-04-20 CZ CZ19942617A patent/CZ287359B6/cs not_active IP Right Cessation
- 1993-04-20 NZ NZ252681A patent/NZ252681A/en not_active IP Right Cessation
- 1993-04-20 AU AU42611/93A patent/AU672793B2/en not_active Ceased
- 1993-04-20 SK SK1272-94A patent/SK282745B6/sk not_active IP Right Cessation
- 1993-04-20 AT AT93911768T patent/ATE219940T1/de not_active IP Right Cessation
- 1993-04-20 CA CA002132740A patent/CA2132740C/en not_active Expired - Fee Related
- 1993-04-20 JP JP5517998A patent/JP2818298B2/ja not_active Expired - Fee Related
- 1993-04-20 HU HU9403055A patent/HU218279B/hu not_active IP Right Cessation
- 1993-04-20 ES ES93911768T patent/ES2179052T3/es not_active Expired - Lifetime
- 1993-04-20 DE DE69332078T patent/DE69332078T2/de not_active Expired - Fee Related
- 1993-04-20 RU RU94046413A patent/RU2126263C1/ru active
1994
- 1994-10-20 KR KR1019940703729A patent/KR950701227A/ko not_active Withdrawn
- 1994-10-21 NO NO19943998A patent/NO315075B1/no not_active IP Right Cessation
- 1994-10-21 FI FI944978A patent/FI111130B/fi active
2000
- 2000-12-08 KR KR10-2000-7013956A patent/KR100414853B1/ko not_active Expired - Fee Related
2003
- 2003-12-31 CY CY0300096A patent/CY2399B1/xx unknown

Also Published As

Publication number	Publication date
CA2132740C (en)	2008-01-15
ATE219940T1 (de)	2002-07-15
FI944978L (fi)	1994-10-21
HU218279B (en)	2000-07-28
DE69332078D1 (de)	2002-08-08
KR950701227A (ko)	1995-03-23
SK282745B6 (sk)	2002-12-03
ES2179052T3 (es)	2003-01-16
HU9403055D0 (en)	1994-12-28
CZ261794A3 (en)	1995-02-15
UA34454C2 (uk)	2001-03-15
AU672793B2 (en)	1996-10-17
RU2126263C1 (ru)	1999-02-20
JP2818298B2 (ja)	1998-10-30
AU4261193A (en)	1993-11-18
WO1993020833A1 (en)	1993-10-28
GB9208712D0 (en)	1992-06-10
NO943998D0 (no)	1994-10-21
DE69332078T2 (de)	2002-12-19
EP0637248A1 (en)	1995-02-08
CZ287359B6 (en)	2000-11-15
KR100414853B1 (da)	2004-01-13
CY2399B1 (en)	2004-09-10
NO943998L (no)	1994-10-21
NZ252681A (en)	1996-02-27
SK127294A3 (en)	1995-04-12
EP0637248B1 (en)	2002-07-03
FI111130B (fi)	2003-06-13
CA2132740A1 (en)	1993-10-28
PT637248E (pt)	2002-11-29
HUT71580A (en)	1995-12-28
RU94046413A (ru)	1996-11-10
JPH07505872A (ja)	1995-06-29
FI944978A0 (fi)	1994-10-21
NO315075B1 (no)	2003-07-07
SG50692A1 (en)	1999-05-25

Publication	Publication Date	Title
FI944978A0 (fi)	1994-10-21	Syklosporiinijohdannaista sisältävä farmaseuttinen koostumus
TNSN92004A1 (fr)	1993-06-08	Derive de la 5h-pyrrolo (3,4-b) pyrazine optiquement actif, sa preparation et les compositions pharmaceutiques qui le contiennent
MX9204379A (es)	1993-02-01	Microemulsiones de agua en aceite auto-emulsificables, estables, farmaceuticamente aceptables.
EP0573423A4 (en)	1994-06-01	Methods and preparations of stable, deodorized oils and pharmaceutical compositions thereof
FI963066A0 (fi)	1996-08-02	Lipofiiliset kantoainevalmisteet
CA2067754A1 (en)	1992-02-25	Preparation for the application of agents in mini-droplets
AU6022890A (en)	1991-02-14	Diarylacetylenes, the preparations and use thereof
UA40634C2 (uk)	2001-08-15	Мікрокапсула, яка містить суспензію твердої біологічно активної сполуки, і спосіб її одержання
CA2180816A1 (en)	1997-01-12	6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients
CA2193337A1 (en)	1997-06-21	1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients
ATE143830T1 (de)	1996-10-15	Mikrokapseln mit wänden aus primären alkoholfunktionen enthaltenden polysacchariden, und zusammensetzungen daraus
MX9204382A (es)	1993-08-01	Composiciones
NO950248D0 (no)	1995-01-23	NG-monometyl-L-argininhydrokloridderivater og anvendelse derav for behandling av septisk sjokk
CO5640115A2 (es)	2006-05-31	3,4-dihidropirido [1,2-a] pirimidinas sustituidas
AU8079891A (en)	1992-01-23	Bile alcohol and drug containing the same as active ingredient
HK1011278A1 (en)	1999-07-09	Macrolide formulations
IT8921516A0 (it)	1989-08-11	Procedimento di microincapsulazione di microorganismi vivi e composizioni farmaceutiche stabili.
SE9004076D0 (sv)	1990-12-20	Anvaendning av 10-acetyl-1,8,9-triacetoxi-antracen som antiinflammatoriskst medel vid framstaellning av farmaceutiska och kosmetiska kompositioner
ITVR920023A0 (it)	1992-03-23	Struttura di supporto per tavoli sedie scaffalerie e simili costituita da elementi modulari
IT8821313V0 (it)	1988-05-27	Dispositivo di bloccaggio per rotelle di poltrone scrivanie e simili.
FR2655344B1 (fr)	1992-04-03	Derives heterocycliques d'acylaminothiazoles, leur preparation et compositions pharmaceutiques en contenant.