DK0639229T3 - Hurtig detektion af antibiotikaresistens i Mycobacterium tuberculosis - Google Patents
Hurtig detektion af antibiotikaresistens i Mycobacterium tuberculosisInfo
- Publication number
- DK0639229T3 DK0639229T3 DK93909875T DK93909875T DK0639229T3 DK 0639229 T3 DK0639229 T3 DK 0639229T3 DK 93909875 T DK93909875 T DK 93909875T DK 93909875 T DK93909875 T DK 93909875T DK 0639229 T3 DK0639229 T3 DK 0639229T3
- Authority
- DK
- Denmark
- Prior art keywords
- resistance
- mycobacterium tuberculosis
- antibiotic resistance
- rapid detection
- gene
- Prior art date
Links
- 241000187479 Mycobacterium tuberculosis Species 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title abstract 2
- 230000003115 biocidal effect Effects 0.000 title 1
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 abstract 4
- QRXWMOHMRWLFEY-UHFFFAOYSA-N isoniazide Chemical compound NNC(=O)C1=CC=NC=C1 QRXWMOHMRWLFEY-UHFFFAOYSA-N 0.000 abstract 2
- JQXXHWHPUNPDRT-WLSIYKJHSA-N rifampicin Chemical compound O([C@](C1=O)(C)O/C=C/[C@@H]([C@H]([C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(C)/C(=O)NC=2C(O)=C3C([O-])=C4C)C)OC)C4=C1C3=C(O)C=2\C=N\N1CC[NH+](C)CC1 JQXXHWHPUNPDRT-WLSIYKJHSA-N 0.000 abstract 2
- 229960001225 rifampicin Drugs 0.000 abstract 2
- 229960005322 streptomycin Drugs 0.000 abstract 2
- 230000002365 anti-tubercular Effects 0.000 abstract 1
- 229960003350 isoniazid Drugs 0.000 abstract 1
- 101150013110 katG gene Proteins 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 230000005180 public health Effects 0.000 abstract 1
- 101150090202 rpoB gene Proteins 0.000 abstract 1
- 101150098466 rpsL gene Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87594092A | 1992-04-30 | 1992-04-30 | |
| US07/929,206 US5633131A (en) | 1992-04-30 | 1992-08-14 | Rapid detection of isoniazid resistance in mycobacterium tuberculosis probes for selecting nucleic acid encoding isoniazid resistance, and methods and kits |
| FR9211098A FR2695650B1 (fr) | 1992-09-17 | 1992-09-17 | Procédé de détection de la résistance des mycobactéries à la rifampicine; kit de diagnostic pour la mise en Óoeuvre. |
| FR9304545A FR2704002B1 (fr) | 1993-04-16 | 1993-04-16 | Methode de detection de la resistance des mycobacteries a la streptomycine, kit de diagnostic pour la mise en oeuvre et sequence nucleotidique du gene rpsl de mycobacterium tuberculosis. |
| PCT/EP1993/001063 WO1993022454A1 (en) | 1992-04-30 | 1993-04-30 | Rapid detection of antibiotic resistance in mycobacterium tuberculosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK0639229T3 true DK0639229T3 (da) | 1999-09-27 |
| DK0639229T4 DK0639229T4 (da) | 2010-03-01 |
Family
ID=27446863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93909875.2T DK0639229T4 (da) | 1992-04-30 | 1993-04-30 | Hurtig detektion af antibiotikaresistens i Mycobacterium tuberculosis |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0639229B2 (da) |
| JP (3) | JP3579049B2 (da) |
| AT (1) | ATE177476T1 (da) |
| CA (1) | CA2134103C (da) |
| DE (1) | DE69323872T3 (da) |
| DK (1) | DK0639229T4 (da) |
| ES (1) | ES2131578T5 (da) |
| GR (1) | GR3030479T3 (da) |
| WO (1) | WO1993022454A1 (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2162868A1 (en) * | 1993-05-13 | 1994-11-24 | William R. Jacobs, Jr. | Methods and compositions for detecting and treating mycobacterial infections using an inha gene |
| US5610012A (en) * | 1994-04-08 | 1997-03-11 | Wisconsin Alumni Research Foundation | DNA probes specific for virulent listeria monocytogenes |
| US5688639A (en) * | 1994-04-18 | 1997-11-18 | Mayo Foundation For Medical Education And Research | Detection of isoniazid resistent strains of M. tuberculosis |
| US5922575A (en) * | 1994-04-18 | 1999-07-13 | Mayo Foundation For Medical Education & Research | Mutations in the katG gene useful for detection of M. tuberculosis |
| US5658733A (en) * | 1994-04-18 | 1997-08-19 | Mayo Foundation For Medical Education And Research | Detection of isoniazid resistant strains of M. tuberculosis |
| GB9506658D0 (en) * | 1995-03-31 | 1995-05-24 | Gatsby Charitable Foundation | Plant pathogen resistance genes and uses thereof |
| US5643723A (en) * | 1994-05-26 | 1997-07-01 | Roche Molecular Systems, Inc. | Detection of a genetic locus encoding resistance to rifampin in mycobacterial cultures and in clinical specimens |
| AU703947B2 (en) * | 1994-06-09 | 1999-04-01 | Innogenetics N.V. | Method for the detection of the antibiotic resistance spectrum of mycobacterium species |
| US5712095A (en) * | 1994-06-16 | 1998-01-27 | Becton Dickinson And Company | Rapid and sensitive detection of antibiotic-resistant mycobacteria using oligonucleotide probes specific for ribosomal RNA precursors |
| US6287865B1 (en) | 1995-03-31 | 2001-09-11 | Plant Bioscience Limited | Cf-2 plant pathogen resistance genes |
| FR2738827B1 (fr) * | 1995-09-18 | 1997-10-17 | Bio Merieux | Detection des enterobacteries |
| US5939300A (en) * | 1996-07-03 | 1999-08-17 | Diversa Corporation | Catalases |
| AR021815A1 (es) * | 1998-09-18 | 2002-08-07 | Univ Nebraska Lincoln | Analisis de alta resolucion de genomas. |
| AU2002247644A1 (en) * | 2001-02-16 | 2002-09-04 | Degussa Ag | Nucleotide sequences of the ribosomal protein s12 gene (rpsl) from corynebacterium glutamicum |
| EP1239040A3 (de) * | 2001-02-16 | 2003-01-08 | Degussa AG | Mutationen im rpoB-Gen L-Lysin produzierender Corynebacterium glutamicum-Stämme und Verfahren zur Herstellung von L-Lysin |
| KR100454585B1 (ko) * | 2001-10-09 | 2004-11-02 | 주식회사 에스제이하이테크 | 마이코박테리아의 균주 감별, 결핵균의 스트레인 감별과항생제 내성을 검출하기 위한 프로브를 포함하는마이크로어레이와 이를 이용한 검출 방법 및 진단 키트 |
| RU2376387C2 (ru) * | 2005-12-26 | 2009-12-20 | Учреждение Российской академии наук Институт молекулярной биологии им. В.А. Энгельгардта РАН | Способ одновременного обнаружения микобактерий туберкулезного комплекса и идентификации мутаций в днк микобактерий, приводящих к устойчивости микроорганизмов к рифампицину и изониазиду, на биологических микрочипах, набор праймеров, биочип и набор олигонуклеотидных зондов, используемые в способе |
| WO2010001923A1 (ja) | 2008-07-02 | 2010-01-07 | ニプロ株式会社 | 結核菌におけるイソニアジド感受性を検出するための方法および試験片 |
| CN102084006B (zh) | 2008-07-02 | 2014-08-20 | 尼普洛株式会社 | 用于检测结核杆菌中的异烟肼敏感性的方法和试验片 |
| BR112012019458B8 (pt) * | 2010-01-26 | 2022-08-02 | Mmag Co Ltd | construção de ácidos nucleicos, transformante, e métodos para produzir piripiropenos |
| CN112823004A (zh) | 2018-06-06 | 2021-05-18 | 米尼奥尔克斯治疗有限公司 | 5-[[4-[2-[5-乙酰基吡啶-2-基]乙氧基]苄基]-1,3-噻唑烷-2,4-二酮及其盐的用途 |
| CN111517947B (zh) * | 2020-03-18 | 2022-05-24 | 西北师范大学 | 一种基于功能化的双边柱[5]芳烃传感器分子及其合成和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3679379D1 (de) * | 1985-11-12 | 1991-06-27 | Hoechst Japan | Streptomycinsensitives gen mit einer vielzahl von klonierungsstellen, dieses gen enthaltender plasmidvektor und diesen vektor enthaltender mikroorganismus. |
| GB8924989D0 (en) * | 1989-11-06 | 1989-12-28 | Scotgen Ltd | Method and device for the detection of antibiotic resistance |
-
1993
- 1993-04-30 DE DE69323872T patent/DE69323872T3/de not_active Expired - Lifetime
- 1993-04-30 CA CA2134103A patent/CA2134103C/en not_active Expired - Lifetime
- 1993-04-30 ES ES93909875T patent/ES2131578T5/es not_active Expired - Lifetime
- 1993-04-30 WO PCT/EP1993/001063 patent/WO1993022454A1/en not_active Ceased
- 1993-04-30 DK DK93909875.2T patent/DK0639229T4/da active
- 1993-04-30 AT AT93909875T patent/ATE177476T1/de active
- 1993-04-30 JP JP51892393A patent/JP3579049B2/ja not_active Expired - Lifetime
- 1993-04-30 EP EP93909875A patent/EP0639229B2/en not_active Expired - Lifetime
-
1999
- 1999-06-10 GR GR990401553T patent/GR3030479T3/el unknown
-
2003
- 2003-01-06 JP JP2003000199A patent/JP3818652B2/ja not_active Expired - Lifetime
- 2003-06-25 JP JP2003180979A patent/JP3905064B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GR3030479T3 (en) | 1999-10-29 |
| JPH07506003A (ja) | 1995-07-06 |
| EP0639229B1 (en) | 1999-03-10 |
| ES2131578T3 (es) | 1999-08-01 |
| DE69323872D1 (de) | 1999-04-15 |
| EP0639229B2 (en) | 2009-11-25 |
| JP3818652B2 (ja) | 2006-09-06 |
| WO1993022454A1 (en) | 1993-11-11 |
| JP2004000136A (ja) | 2004-01-08 |
| JP2004154125A (ja) | 2004-06-03 |
| JP3579049B2 (ja) | 2004-10-20 |
| ES2131578T5 (es) | 2010-03-31 |
| JP3905064B2 (ja) | 2007-04-18 |
| DE69323872T2 (de) | 1999-09-30 |
| CA2134103C (en) | 2010-06-22 |
| DK0639229T4 (da) | 2010-03-01 |
| DE69323872T3 (de) | 2010-06-02 |
| EP0639229A1 (en) | 1995-02-22 |
| CA2134103A1 (en) | 1993-11-11 |
| ATE177476T1 (de) | 1999-03-15 |
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