DK0640141T3 - Nucleinsyre-fragmenter og fremgangsmåde til forøgelse af lysin og threonin indholdet i plantefrø - Google Patents

Nucleinsyre-fragmenter og fremgangsmåde til forøgelse af lysin og threonin indholdet i plantefrø

Info

Publication number
DK0640141T3
DK0640141T3 DK93908395T DK93908395T DK0640141T3 DK 0640141 T3 DK0640141 T3 DK 0640141T3 DK 93908395 T DK93908395 T DK 93908395T DK 93908395 T DK93908395 T DK 93908395T DK 0640141 T3 DK0640141 T3 DK 0640141T3
Authority
DK
Denmark
Prior art keywords
nucleic acid
acid fragments
plant seeds
threonine content
increasing lysine
Prior art date
Application number
DK93908395T
Other languages
English (en)
Inventor
Saverio Carl Falco
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Application granted granted Critical
Publication of DK0640141T3 publication Critical patent/DK0640141T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8251—Amino acid content, e.g. synthetic storage proteins, altering amino acid biosynthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8251—Amino acid content, e.g. synthetic storage proteins, altering amino acid biosynthesis
    • C12N15/8254—Tryptophan or lysine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0026—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK93908395T 1992-03-19 1993-03-18 Nucleinsyre-fragmenter og fremgangsmåde til forøgelse af lysin og threonin indholdet i plantefrø DK0640141T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85541492A 1992-03-19 1992-03-19
PCT/US1993/002480 WO1993019190A1 (en) 1992-03-19 1993-03-18 Nucleic acid fragments and methods for increasing the lysine and threonine content of the seeds of plants

Publications (1)

Publication Number Publication Date
DK0640141T3 true DK0640141T3 (da) 2003-07-21

Family

ID=25321215

Family Applications (2)

Application Number Title Priority Date Filing Date
DK93908395T DK0640141T3 (da) 1992-03-19 1993-03-18 Nucleinsyre-fragmenter og fremgangsmåde til forøgelse af lysin og threonin indholdet i plantefrø
DK03009812T DK1394257T3 (da) 1992-03-19 1993-03-18 Nukleinsyrefragmenter og fremgangsmåder til forögelse af lysin- og threonin-indholdet i fröene fra planter

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK03009812T DK1394257T3 (da) 1992-03-19 1993-03-18 Nukleinsyrefragmenter og fremgangsmåder til forögelse af lysin- og threonin-indholdet i fröene fra planter

Country Status (9)

Country Link
EP (2) EP0640141B1 (da)
JP (1) JPH07504821A (da)
AU (1) AU675933B2 (da)
CA (1) CA2132414C (da)
DE (2) DE69334163T2 (da)
DK (2) DK0640141T3 (da)
MX (1) MX9301521A (da)
WO (1) WO1993019190A1 (da)
ZA (1) ZA931978B (da)

Families Citing this family (41)

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US5550318A (en) * 1990-04-17 1996-08-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US7705215B1 (en) * 1990-04-17 2010-04-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US6329574B1 (en) 1990-01-22 2001-12-11 Dekalb Genetics Corporation High lysine fertile transgenic corn plants
WO1991010725A1 (en) 1990-01-22 1991-07-25 Dekalb Plant Genetics Fertile transgenic corn plants
EP0663921B1 (en) * 1992-10-05 2002-05-08 North Carolina State University Method for increasing expression and reducing expression variability of foreign genes in plant cells
SK279915B6 (sk) * 1992-11-10 1999-05-07 Ajinomoto Co. Dna kódujúca aspartokinázu iii, transformovaný mik
DE69428290T2 (de) * 1993-01-13 2002-04-18 Pioneer Hi-Bred International, Inc. Derivate von alpha-hordothionin mit höherem behalt an lysin
US6326527B1 (en) 1993-08-25 2001-12-04 Dekalb Genetics Corporation Method for altering the nutritional content of plant seed
US6118047A (en) 1993-08-25 2000-09-12 Dekalb Genetic Corporation Anthranilate synthase gene and method of use thereof for conferring tryptophan overproduction
BR9408228A (pt) * 1993-11-30 1997-08-26 Du Pont Gene quimérico planta sementes método para obter uma planta planta transformada e fragmento de ácido nucléico
JPH07155184A (ja) * 1993-12-08 1995-06-20 Ajinomoto Co Inc 発酵法によるｌ−リジンの製造法
IL113685A0 (en) * 1994-05-13 1995-08-31 Du Pont Nucleic acid fragments chimeric genes and methods for increasing the methionine content of the seeds of plants
BR9510174A (pt) * 1994-07-08 1997-11-04 Du Pont Gene quimérico planta sementes método para aumentar o teor de treonina das sementes de plantas
WO1996038574A1 (en) * 1995-05-31 1996-12-05 Pioneer Hi-Bred International, Inc. Methods of increasing accumulation of essential amino acids in seeds
MX9709351A (es) * 1995-06-02 1998-02-28 Pioneer Hi Bred Int Derivados de alfa-hordotionina con alto contenido de treonina.
CN1192239A (zh) * 1995-06-02 1998-09-02 先锋高级育种国际公司 α-hordothionin的高甲硫氨酸衍生物
US5989875A (en) * 1995-06-13 1999-11-23 Ajinomoto Co., Inc. Method of process for producing L-lysine by fermentation
US6891084B1 (en) 1996-04-26 2005-05-10 Ajinomoto Co., Inc. DNA encoding raffinose synthase from soybean
US6166292A (en) * 1996-04-26 2000-12-26 Ajinomoto Co., Inc. Raffinose synthetase gene, method of producing raffinose and transgenic plant
JP4088982B2 (ja) * 1996-10-15 2008-05-21 味の素株式会社 発酵法によるｌ−アミノ酸の製造法
CZ174699A3 (cs) * 1996-11-18 1999-09-15 Avebe Chimerní konstrukce dvou genů, expresivní vektor, transgenní rostlina nebo její části s přirozeně vysokým obsahem vody, které nadměrně produkují alespoň dvě aminokyseliny aspartátové rodiny a způsob získání takové rostliny
HUP0002305A3 (en) * 1997-03-27 2002-09-30 Du Pont Chimeric genes and methods for increasing the lysine content of the seeds of plants
WO1999004024A2 (en) 1997-07-15 1999-01-28 Dow Agrosciences Llc Nucleotide sequences of genes encoding sink proteins and uses thereof for improving the nutritional quality of feeds
US6825398B2 (en) * 2001-09-05 2004-11-30 Monsanto Company Seed specific 7Sα promoter for expressing genes in plants
US8008545B2 (en) 2003-04-15 2011-08-30 Basf Plant Science Gmbh Process for the production of fine chemicals
EP2434019A1 (en) 2003-08-01 2012-03-28 BASF Plant Science GmbH Process for the production of fine chemicals
US7157281B2 (en) * 2003-12-11 2007-01-02 Monsanto Technology Llc High lysine maize compositions and event LY038 maize plants
US7855323B2 (en) 2004-02-10 2010-12-21 Monsanto Technology Llc Recombinant DNA for gene suppression
EP1735452A2 (en) 2004-04-06 2006-12-27 Metanomics GmbH Process for the production of fine chemicals
EP2080769A3 (en) 2004-07-02 2010-12-01 Metanomics GmbH Process for the production of fine chemicals
EP1974049A2 (en) 2004-12-17 2008-10-01 Metanomics GmbH Process for the control of production of fine chemicals
US20140199313A1 (en) 2005-03-02 2014-07-17 Metanomics Gmbh Process for the Production of Fine Chemicals
CA2598792A1 (en) 2005-03-02 2006-09-08 Metanomics Gmbh Process for the production of fine chemicals
UA102367C2 (ru) * 2005-10-03 2013-07-10 Монсанто Текнолоджи Ллс Семя трансгенной кукурузы с повышенным содержанием лизина
AU2007299219A1 (en) 2006-04-05 2008-03-27 Metanomics Gmbh Process for the production of a fine chemical
EP2134870B1 (en) 2007-03-28 2014-02-26 Monsanto Technology, LLC Utility of snp markers associated with major soybean plant maturity and growth habit genomic regions
US9049823B2 (en) 2007-09-11 2015-06-09 Monsanto Technology Llc Increased alpha-prime beta-conglycinin soybeans
CN102076856B (zh) 2008-06-30 2014-12-31 孟山都技术公司 用于提高植物中的氨基酸含量的组合物和方法
CN103773745B (zh) 2012-10-18 2018-03-23 中粮生物化学（安徽）股份有限公司 天冬氨酸激酶iii突变体及其宿主细胞和应用
CN106086011B (zh) * 2016-06-18 2019-10-18 北京大北农科技集团股份有限公司 用于检测除草剂耐受性大豆植物dbn9004的核酸序列及其检测方法
CN113201514B (zh) 2020-10-16 2022-09-06 中国科学院天津工业生物技术研究所 具有天冬氨酸激酶活性的多肽及其在生产氨基酸中的应用

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Publication number Priority date Publication date Assignee Title
US5258300A (en) * 1988-06-09 1993-11-02 Molecular Genetics Research And Development Limited Partnership Method of inducing lysine overproduction in plants
DE3943117A1 (de) * 1989-12-27 1991-07-04 Forschungszentrum Juelich Gmbh Verfahren zur fermentativen herstellung von aminosaeure, insbesondere l-lysin, dafuer geeignete mikroorganismen und rekombinante dna
EP0485970A3 (en) * 1990-11-13 1992-07-01 Yeda Research And Development Company Limited Transgenic plants overproducing threonine and lysine
US7746705B2 (en) * 2007-12-10 2010-06-29 Spansion Llc Selective application of word line bias to minimize fringe effects in electromagnetic fields during erase of nonvolatile memory

Also Published As

Publication number Publication date
EP0640141A1 (en) 1995-03-01
DE69334163D1 (de) 2007-09-20
CA2132414C (en) 2009-01-27
EP0640141B1 (en) 2003-05-14
AU3923393A (en) 1993-10-21
CA2132414A1 (en) 1993-09-30
EP1394257A1 (en) 2004-03-03
DE69332974D1 (de) 2003-06-18
AU675933B2 (en) 1997-02-27
WO1993019190A1 (en) 1993-09-30
MX9301521A (es) 1993-09-01
ZA931978B (en) 1994-09-19
DK1394257T3 (da) 2007-12-10
JPH07504821A (ja) 1995-06-01
DE69334163T2 (de) 2008-04-30
DE69332974T2 (de) 2004-05-19
EP1394257B1 (en) 2007-08-08

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