DK0643063T3 - Fremgangsmåde til fremstilling af et højereordens cupratkompleks - Google Patents

Fremgangsmåde til fremstilling af et højereordens cupratkompleks

Info

Publication number: DK0643063T3
Authority: DK; Denmark
Prior art keywords: higher order; preparing; order cuprate; cuprate complex; complex
Prior art date: 1990-04-17

Application number

DK94116373T

Other languages

Danish (da)

English (en)

Inventor

John Henry Dygos

James Richard Behling

Ng John Sau-Hoi

Kevin Anthony Babiak

Original Assignee

Searle & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-17

Filing date

1991-04-15

Publication date

2000-04-25

1991-04-15 Application filed by Searle & Co filed Critical Searle & Co

2000-04-25 Application granted granted Critical

2000-04-25 Publication of DK0643063T3 publication Critical patent/DK0643063T3/da

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
239000010949 copper Substances 0.000 abstract 2
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 abstract 1
150000001345 alkine derivatives Chemical class 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
-1 chloride hydride Chemical compound 0.000 abstract 1
229910052802 copper Inorganic materials 0.000 abstract 1
DOBRDRYODQBAMW-UHFFFAOYSA-N copper(i) cyanide Chemical compound [Cu+].N#[C-] DOBRDRYODQBAMW-UHFFFAOYSA-N 0.000 abstract 1
ZMMRKRFMSDTOLV-UHFFFAOYSA-N cyclopenta-1,3-diene zirconium Chemical compound [Zr].C1C=CC=C1.C1C=CC=C1 ZMMRKRFMSDTOLV-UHFFFAOYSA-N 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229910052726 zirconium Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/08—Copper compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Catalysts (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DK94116373T 1990-04-17 1991-04-15 Fremgangsmåde til fremstilling af et højereordens cupratkompleks DK0643063T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/510,349 US5055604A (en)	1990-04-17	1990-04-17	Process for preparing prostaglandin analogs using organozirconium compounds

Publications (1)

Publication Number	Publication Date
DK0643063T3 true DK0643063T3 (da)	2000-04-25

Family

ID=24030385

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK94116373T DK0643063T3 (da)	1990-04-17	1991-04-15	Fremgangsmåde til fremstilling af et højereordens cupratkompleks
DK91105951.7T DK0452843T3 (da)	1990-04-17	1991-04-15	Fremgangsmåde til fremstilling af prostaglandinanaloge ved anvendelse af organozirconiumforbindelser

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK91105951.7T DK0452843T3 (da)	1990-04-17	1991-04-15	Fremgangsmåde til fremstilling af prostaglandinanaloge ved anvendelse af organozirconiumforbindelser

Country Status (12)

Country	Link
US (1)	US5055604A (de)
EP (2)	EP0643063B1 (de)
JP (1)	JPH04224555A (de)
KR (2)	KR100208496B1 (de)
AT (2)	ATE123768T1 (de)
CA (1)	CA2040468C (de)
DE (2)	DE69131944T2 (de)
DK (2)	DK0643063T3 (de)
ES (2)	ES2073060T3 (de)
GR (1)	GR3033236T3 (de)
IE (1)	IE911273A1 (de)
PT (1)	PT97368A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5618959A (en) *	1995-03-10	1997-04-08	Vivus Incorporated	Process for preparing prostaglandin E1, E2 and analogs thereof using furylcopper reagents
US6030959A (en) *	1997-04-04	2000-02-29	Monsanto Company	Gastro-specific prodrugs
US6413945B1 (en) *	1997-04-04	2002-07-02	Pharmacia Corporation	Gastro-specific prodrugs
KR20030002365A (ko) *	2001-06-29	2003-01-09	주식회사 하이닉스반도체	반도체 소자의 포토 레지스트 중합체용 단량체 및 이의제조 방법
KR101045935B1 (ko)	2009-03-11	2011-07-01	연성정밀화학(주)	프로스타글란딘 유도체의 제조방법
HU231185B1 (hu)	2017-07-11	2021-07-28	CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt.	Eljárás Misoprostol előállítására és tisztítására

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3950406A (en) *	1972-07-24	1976-04-13	American Cyanamid Company	Hydroxylated 15-deoxy derivatives of 9-hydroxy-13-trans-prostenoic acid
US3962353A (en) *	1972-09-29	1976-06-08	Wisconsin Alumni Research Foundation	3-Substituted iodo alkenyl compounds and methods for preparing same
US3962352A (en) *	1972-09-29	1976-06-08	Wisconsin Alumni Research Foundation	3-Substituted iodo alkenyl compounds and methods for preparing same
US3962351A (en) *	1972-09-29	1976-06-08	Wisconsin Alumni Research Foundation	3-Substituted iodo alkenyl compounds and methods for preparing same
US3932479A (en) *	1973-04-27	1976-01-13	American Cyanamid Company	Lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates
US4007210A (en) *	1973-04-27	1977-02-08	American Cyanamid Company	Novel 3-triphenylmethoxy-1-alkynes, 3-triphenylmethoxy-1-trans-alkenyl-dialkyl-alanes, and lithium 3-triphenyl-methoxy-1-trans-alkenyl-dialkyl-alanates
US3965143A (en) *	1974-03-26	1976-06-22	G. D. Searle & Co.	16-Oxygenated prostanoic acid derivatives
US4983753A (en) *	1981-05-21	1991-01-08	Floyd Jr Middleton B	Precursors and synthesis of di-(methyl)-16,16-(dimethyl)-11-alpha,15-alpha beta-dihydroxy-9-oxo-2,13-trans,trans-prostadienoates
US4415501A (en) *	1981-12-16	1983-11-15	American Cyanamid Company	Alkenylzirconium reagents useful for prostaglandin analog synthesis
US4822909A (en) *	1983-06-10	1989-04-18	Asashi Glass Company Ltd.	7-fluoroprostaglandins and process for their production
DK40485A (da) *	1984-03-02	1985-09-03	Hoffmann La Roche	Prostaglandin-mellemprodukter
DE3571319D1 (en) *	1984-10-08	1989-08-10	Teijin Ltd	Process for producing 2,3-disubstituted -4-substituted cyclopentanones, enantiomorphs, or mixtures thereof
US4873360A (en) *	1986-07-10	1989-10-10	Board Of Governors Of Wayne State University	Process for the preparation of cyclopentanoids and novel intermediates produced thereby
US4777275A (en) *	1987-06-09	1988-10-11	G. D. Searle & Co.	Process of preparing higher order cuprate complexes
US4904820A (en) *	1987-06-09	1990-02-27	G. D. Searle & Co.	Process for substituting a hydrocarbon group
US4916238A (en) *	1988-12-13	1990-04-10	Syntex (U.S.A.) Inc.	Process for preparing allenic prostanoic acid derivatives
US5072010A (en) *	1990-04-04	1991-12-10	University Of California	Transmetalations from zirconium to copper intermediates

1990
- 1990-04-17 US US07/510,349 patent/US5055604A/en not_active Expired - Lifetime
1991
- 1991-04-15 ES ES91105951T patent/ES2073060T3/es not_active Expired - Lifetime
- 1991-04-15 ES ES94116373T patent/ES2143517T3/es not_active Expired - Lifetime
- 1991-04-15 KR KR1019910005994A patent/KR100208496B1/ko not_active Expired - Fee Related
- 1991-04-15 PT PT97368A patent/PT97368A/pt not_active Application Discontinuation
- 1991-04-15 AT AT91105951T patent/ATE123768T1/de not_active IP Right Cessation
- 1991-04-15 EP EP94116373A patent/EP0643063B1/de not_active Expired - Lifetime
- 1991-04-15 DK DK94116373T patent/DK0643063T3/da active
- 1991-04-15 DE DE69131944T patent/DE69131944T2/de not_active Expired - Fee Related
- 1991-04-15 CA CA002040468A patent/CA2040468C/en not_active Expired - Fee Related
- 1991-04-15 DK DK91105951.7T patent/DK0452843T3/da active
- 1991-04-15 AT AT94116373T patent/ATE189222T1/de not_active IP Right Cessation
- 1991-04-15 DE DE69110343T patent/DE69110343T2/de not_active Expired - Fee Related
- 1991-04-15 EP EP91105951A patent/EP0452843B1/de not_active Expired - Lifetime
- 1991-04-16 IE IE127391A patent/IE911273A1/en unknown
- 1991-04-16 JP JP3084081A patent/JPH04224555A/ja active Pending
1998
- 1998-12-17 KR KR1019980055838A patent/KR100226368B1/ko not_active Expired - Fee Related
2000
- 2000-04-14 GR GR20000400918T patent/GR3033236T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0643063A3 (de)	1995-10-11
DK0452843T3 (da)	1995-08-14
DE69110343D1 (de)	1995-07-20
EP0452843A2 (de)	1991-10-23
JPH04224555A (ja)	1992-08-13
US5055604A (en)	1991-10-08
ATE123768T1 (de)	1995-06-15
CA2040468A1 (en)	1991-10-18
EP0643063B1 (de)	2000-01-26
DE69131944D1 (de)	2000-03-02
ES2143517T3 (es)	2000-05-16
KR100226368B1 (en)	1999-10-15
IE911273A1 (en)	1991-10-23
GR3033236T3 (en)	2000-09-29
EP0452843B1 (de)	1995-06-14
DE69110343T2 (de)	1995-12-21
EP0452843A3 (en)	1992-07-29
ES2073060T3 (es)	1995-08-01
ATE189222T1 (de)	2000-02-15
KR910018351A (ko)	1991-11-30
KR100208496B1 (ko)	1999-07-15
PT97368A (pt)	1992-01-31
EP0643063A2 (de)	1995-03-15
DE69131944T2 (de)	2000-06-15
CA2040468C (en)	2004-10-26

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RO81037B (ro)	1983-01-30	Procedeu de preparare a unor 4-dezacelilvincaleucoblastin-c3-carboxhidrazide
DK199489A (da)	1989-10-27	Fremgangsmaade til fremstilling af n-t-alkyl-1,2-diacylhydraziner
GB8714371D0 (en)	1987-07-22	Process
FR2441189B1 (fr)	1985-08-30	Dispositif d'eclairage pour microscope a fluorescence
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GR3033236T3 (en)	2000-09-29	Process for preparing a higher cuprate complex.
ES9100017A1 (es)	1991-04-16	Un procedimiento para la preparacion de 2-amino-6-cloropurina.
KR840005146A (ko)	1984-11-03	N-(2-메톡시에틸)-노르옥시모르폰의 제조방법
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JPS56141360A (en)	1981-11-05	Fluorescent whitner mixture
ES2026416A6 (es)	1992-04-16	Procedimiento para la preparacion de triazolil-isopropanol.
JPS6438057A (en)	1989-02-08	Preparation of optionally substituted ethane sulfobetain compound
EP0331420A3 (de)	1991-01-16	Verfahren zur Herstellung von 1-Aminoanthrachinonen
DE3564426D1 (en)	1988-09-22	Polyprenyl compound, process of producing it and pharmaceutical use
CS363490A3 (en)	1992-11-18	Process for preparing novel esters of beta-carboline-3-carboxylic acidsbeing substituted in positions 5 or 6
DE3477003D1 (en)	1989-04-13	Process for the preparation of 17-alpha-acyloxy-6-chloro-1-alpha,2-alpha-methylene-4,6-pregnadiene-3-20-diones
ZA90755B (en)	1990-10-31	Process for the preparation of 1-alkylthio-and 1-benzylthio-1-formylcyclopropanes
JPS57163371A (en)	1982-10-07	Preparation of hydroquinone derivative
FR2603390B1 (fr)	1993-01-08	Posemetre pour appareils d'eclairage photographique
HUT41776A (en)	1987-05-28	Process for producing ergolinyl- thiourea derivatives
ES462983A1 (es)	1978-06-16	Un procedimiento para la obtencion de alfa-2,5-9-trimetil- 2'-5 - dimetiltieno (3,4-f) morfano.
ES8608534A1 (es)	1986-07-16	Procedimiento para la fabricacion de etoposido.