DK0650496T3 - Anti-inflammatoriske forbindelser til oftalmisk anvendelse - Google Patents

Anti-inflammatoriske forbindelser til oftalmisk anvendelse

Info

Publication number
DK0650496T3
DK0650496T3 DK93913939T DK93913939T DK0650496T3 DK 0650496 T3 DK0650496 T3 DK 0650496T3 DK 93913939 T DK93913939 T DK 93913939T DK 93913939 T DK93913939 T DK 93913939T DK 0650496 T3 DK0650496 T3 DK 0650496T3
Authority
DK
Denmark
Prior art keywords
compounds
inflammatory compounds
ophthalmic use
inflammatory
inflammed
Prior art date
Application number
DK93913939T
Other languages
English (en)
Inventor
J Boltralik John
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Application granted granted Critical
Publication of DK0650496T3 publication Critical patent/DK0650496T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK93913939T 1990-11-13 1993-05-17 Anti-inflammatoriske forbindelser til oftalmisk anvendelse DK0650496T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61359590A 1990-11-13 1990-11-13
PCT/US1993/004671 WO1994026769A1 (en) 1990-11-13 1993-05-17 Anti-inflammatory compounds for ophthalmic use
CA002140345A CA2140345C (en) 1990-11-13 1993-05-17 Anti-inflammatory compounds for ophthalmic use

Publications (1)

Publication Number Publication Date
DK0650496T3 true DK0650496T3 (da) 1999-06-14

Family

ID=27169933

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93913939T DK0650496T3 (da) 1990-11-13 1993-05-17 Anti-inflammatoriske forbindelser til oftalmisk anvendelse

Country Status (8)

Country Link
EP (1) EP0650496B1 (da)
AT (1) ATE171187T1 (da)
AU (1) AU676481B2 (da)
CA (1) CA2140345C (da)
DE (1) DE69321123T2 (da)
DK (1) DK0650496T3 (da)
ES (1) ES2120503T3 (da)
WO (1) WO1994026769A1 (da)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4181720A (en) * 1978-04-05 1980-01-01 Syntex (U.S.A.) Inc. Corticosteroid antiinflammatory agents
US4968822A (en) * 1987-12-11 1990-11-06 Taisho Pharmaceutical Co., Ltd. 21-alkoxysteroid compounds
JPH02134396A (ja) * 1988-11-15 1990-05-23 Taisho Pharmaceut Co Ltd 21−アルコキシプレグナン誘導体

Also Published As

Publication number Publication date
ES2120503T3 (es) 1998-11-01
CA2140345C (en) 2001-01-16
EP0650496A1 (en) 1995-05-03
AU4379093A (en) 1994-12-12
WO1994026769A1 (en) 1994-11-24
EP0650496B1 (en) 1998-09-16
DE69321123T2 (de) 1999-03-04
ATE171187T1 (de) 1998-10-15
CA2140345A1 (en) 1994-11-24
DE69321123D1 (de) 1998-10-22
AU676481B2 (en) 1997-03-13
HK1013295A1 (en) 1999-08-20

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