ATE171187T1 - Entzündungshemmende verbindungen zur ophthalmischer verwendung - Google Patents
Entzündungshemmende verbindungen zur ophthalmischer verwendungInfo
- Publication number
- ATE171187T1 ATE171187T1 AT93913939T AT93913939T ATE171187T1 AT E171187 T1 ATE171187 T1 AT E171187T1 AT 93913939 T AT93913939 T AT 93913939T AT 93913939 T AT93913939 T AT 93913939T AT E171187 T1 ATE171187 T1 AT E171187T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- inflammatory compounds
- ophthalmic use
- inflammatory
- inflammed
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 230000001684 chronic effect Effects 0.000 abstract 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 abstract 1
- 229960003957 dexamethasone Drugs 0.000 abstract 1
- 230000004410 intraocular pressure Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- -1 steroid compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61359590A | 1990-11-13 | 1990-11-13 | |
| PCT/US1993/004671 WO1994026769A1 (en) | 1990-11-13 | 1993-05-17 | Anti-inflammatory compounds for ophthalmic use |
| CA002140345A CA2140345C (en) | 1990-11-13 | 1993-05-17 | Anti-inflammatory compounds for ophthalmic use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE171187T1 true ATE171187T1 (de) | 1998-10-15 |
Family
ID=27169933
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93913939T ATE171187T1 (de) | 1990-11-13 | 1993-05-17 | Entzündungshemmende verbindungen zur ophthalmischer verwendung |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0650496B1 (de) |
| AT (1) | ATE171187T1 (de) |
| AU (1) | AU676481B2 (de) |
| CA (1) | CA2140345C (de) |
| DE (1) | DE69321123T2 (de) |
| DK (1) | DK0650496T3 (de) |
| ES (1) | ES2120503T3 (de) |
| WO (1) | WO1994026769A1 (de) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4181720A (en) * | 1978-04-05 | 1980-01-01 | Syntex (U.S.A.) Inc. | Corticosteroid antiinflammatory agents |
| US4968822A (en) * | 1987-12-11 | 1990-11-06 | Taisho Pharmaceutical Co., Ltd. | 21-alkoxysteroid compounds |
| JPH02134396A (ja) * | 1988-11-15 | 1990-05-23 | Taisho Pharmaceut Co Ltd | ２１−アルコキシプレグナン誘導体 |
-
1993
- 1993-05-17 AU AU43790/93A patent/AU676481B2/en not_active Ceased
- 1993-05-17 CA CA002140345A patent/CA2140345C/en not_active Expired - Fee Related
- 1993-05-17 DE DE69321123T patent/DE69321123T2/de not_active Expired - Fee Related
- 1993-05-17 AT AT93913939T patent/ATE171187T1/de not_active IP Right Cessation
- 1993-05-17 ES ES93913939T patent/ES2120503T3/es not_active Expired - Lifetime
- 1993-05-17 WO PCT/US1993/004671 patent/WO1994026769A1/en not_active Ceased
- 1993-05-17 EP EP93913939A patent/EP0650496B1/de not_active Expired - Lifetime
- 1993-05-17 DK DK93913939T patent/DK0650496T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| HK1013295A1 (en) | 1999-08-20 |
| DK0650496T3 (da) | 1999-06-14 |
| AU4379093A (en) | 1994-12-12 |
| WO1994026769A1 (en) | 1994-11-24 |
| DE69321123D1 (de) | 1998-10-22 |
| AU676481B2 (en) | 1997-03-13 |
| ES2120503T3 (es) | 1998-11-01 |
| CA2140345A1 (en) | 1994-11-24 |
| EP0650496B1 (de) | 1998-09-16 |
| DE69321123T2 (de) | 1999-03-04 |
| EP0650496A1 (de) | 1995-05-03 |
| CA2140345C (en) | 2001-01-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |