DK0667166T3 - Emulsionspræparat med 1alpha, 24-(OH)2-vitamin D3 - Google Patents
Emulsionspræparat med 1alpha, 24-(OH)2-vitamin D3Info
- Publication number
- DK0667166T3 DK0667166T3 DK94925612T DK94925612T DK0667166T3 DK 0667166 T3 DK0667166 T3 DK 0667166T3 DK 94925612 T DK94925612 T DK 94925612T DK 94925612 T DK94925612 T DK 94925612T DK 0667166 T3 DK0667166 T3 DK 0667166T3
- Authority
- DK
- Denmark
- Prior art keywords
- weight
- vitamin
- parts
- oil component
- surfactants
- Prior art date
Links
- 239000011647 vitamin D3 Substances 0.000 title abstract 3
- 229940021056 vitamin d3 Drugs 0.000 title abstract 3
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title 1
- 239000000839 emulsion Substances 0.000 title 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 title 1
- 235000005282 vitamin D3 Nutrition 0.000 title 1
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 abstract 4
- 239000004094 surface-active agent Substances 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 abstract 2
- 229960000541 cetyl alcohol Drugs 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 abstract 1
- 229940032094 squalane Drugs 0.000 abstract 1
- 239000003871 white petrolatum Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21726193 | 1993-09-01 | ||
| PCT/JP1994/001443 WO1995006482A1 (en) | 1993-09-01 | 1994-09-01 | 1α,24-(OH)2-VITAMIN D3 EMULSION COMPOSITION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0667166T3 true DK0667166T3 (da) | 2000-10-16 |
Family
ID=16701374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94925612T DK0667166T3 (da) | 1993-09-01 | 1994-09-01 | Emulsionspræparat med 1alpha, 24-(OH)2-vitamin D3 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5612327A (da) |
| EP (1) | EP0667166B1 (da) |
| JP (1) | JP3045179B2 (da) |
| KR (1) | KR100221045B1 (da) |
| CN (1) | CN1082818C (da) |
| AT (1) | ATE195431T1 (da) |
| CA (1) | CA2148109C (da) |
| CZ (1) | CZ284261B6 (da) |
| DE (1) | DE69425552T2 (da) |
| DK (1) | DK0667166T3 (da) |
| ES (1) | ES2148340T3 (da) |
| NO (1) | NO312227B1 (da) |
| PL (1) | PL175492B1 (da) |
| PT (1) | PT667166E (da) |
| SG (1) | SG52313A1 (da) |
| SK (1) | SK279913B6 (da) |
| WO (1) | WO1995006482A1 (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5763429A (en) * | 1993-09-10 | 1998-06-09 | Bone Care International, Inc. | Method of treating prostatic diseases using active vitamin D analogues |
| US6242434B1 (en) * | 1997-08-08 | 2001-06-05 | Bone Care International, Inc. | 24-hydroxyvitamin D, analogs and uses thereof |
| AU711716B2 (en) | 1995-04-21 | 1999-10-21 | Sekisui Kagaku Kogyo Kabushiki Kaisha | External preparations for treating dermatoses |
| US20040039030A1 (en) * | 1996-09-27 | 2004-02-26 | Hoechst Akeengesellschaft | Use of 1-hydroxy-2-pyridones for the treatment of seborrheic dermatitis |
| DE19639816A1 (de) * | 1996-09-27 | 1998-04-02 | Hoechst Ag | Antimykotische Mittel mit hoher Wirkstofffreisetzung |
| US20020128240A1 (en) * | 1996-12-30 | 2002-09-12 | Bone Care International, Inc. | Treatment of hyperproliferative diseases using active vitamin D analogues |
| US6566353B2 (en) * | 1996-12-30 | 2003-05-20 | Bone Care International, Inc. | Method of treating malignancy associated hypercalcemia using active vitamin D analogues |
| US20030129194A1 (en) * | 1997-02-13 | 2003-07-10 | Bone Care International, Inc. | Targeted therapeutic delivery of vitamin D compounds |
| US6087350A (en) * | 1997-08-29 | 2000-07-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of pretreatment chemicals to enhance efficacy of cytotoxic agents |
| JP4046363B2 (ja) * | 1998-03-04 | 2008-02-13 | 帝人株式会社 | 活性型ビタミンｄ３乳剤性ローション剤 |
| ES2368824T3 (es) * | 1998-03-27 | 2011-11-22 | Oregon Health & Science University | Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos. |
| US8263580B2 (en) * | 1998-09-11 | 2012-09-11 | Stiefel Research Australia Pty Ltd | Vitamin formulation |
| AU7895601A (en) * | 2000-07-18 | 2002-01-30 | Bone Care Int Inc | Stabilized 1alpha-hydroxy vitamin d |
| JP2005515996A (ja) * | 2001-12-03 | 2005-06-02 | ノバセア インコーポレイティッド | 活性型ビタミンｄ化合物を含む薬学的組成物 |
| US20050026877A1 (en) * | 2002-12-03 | 2005-02-03 | Novacea, Inc. | Pharmaceutical compositions comprising active vitamin D compounds |
| US20050020546A1 (en) * | 2003-06-11 | 2005-01-27 | Novacea, Inc. | Pharmaceutical compositions comprising active vitamin D compounds |
| US20060189586A1 (en) * | 2003-06-11 | 2006-08-24 | Cleland Jeffrey L | Pharmaceutical compositions comprising active vitamin D compounds |
| US7534894B2 (en) | 2003-09-25 | 2009-05-19 | Wyeth | Biphenyloxy-acids |
| US20060003950A1 (en) * | 2004-06-30 | 2006-01-05 | Bone Care International, Inc. | Method of treating prostatic diseases using a combination of vitamin D analogues and other agents |
| US7094775B2 (en) * | 2004-06-30 | 2006-08-22 | Bone Care International, Llc | Method of treating breast cancer using a combination of vitamin D analogues and other agents |
| EP2526930B1 (en) * | 2005-06-01 | 2013-12-25 | GlaxoSmithKline Intellectual Property Development Limited | Vitamin formulation |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6226223A (ja) * | 1985-07-25 | 1987-02-04 | Teijin Ltd | 乾癬治療剤 |
| CA1272953A (en) * | 1984-10-08 | 1990-08-21 | Yuji Makino | Pharmaceutical composition for external use containing active-type vitamin d.sub.3 |
| JPH0774144B2 (ja) * | 1986-03-12 | 1995-08-09 | 久光製薬株式会社 | 尿素を含有する皮膚用組成物 |
| GB9226860D0 (en) * | 1992-12-23 | 1993-02-17 | Leo Pharm Prod Ltd | Novel treatment |
-
1994
- 1994-09-01 CA CA002148109A patent/CA2148109C/en not_active Expired - Lifetime
- 1994-09-01 WO PCT/JP1994/001443 patent/WO1995006482A1/ja not_active Ceased
- 1994-09-01 PL PL94308748A patent/PL175492B1/pl unknown
- 1994-09-01 KR KR1019950701720A patent/KR100221045B1/ko not_active Expired - Lifetime
- 1994-09-01 CZ CZ951132A patent/CZ284261B6/cs not_active IP Right Cessation
- 1994-09-01 EP EP94925612A patent/EP0667166B1/en not_active Expired - Lifetime
- 1994-09-01 JP JP7508038A patent/JP3045179B2/ja not_active Expired - Lifetime
- 1994-09-01 DE DE69425552T patent/DE69425552T2/de not_active Expired - Lifetime
- 1994-09-01 US US08/428,106 patent/US5612327A/en not_active Expired - Lifetime
- 1994-09-01 DK DK94925612T patent/DK0667166T3/da active
- 1994-09-01 PT PT94925612T patent/PT667166E/pt unknown
- 1994-09-01 AT AT94925612T patent/ATE195431T1/de active
- 1994-09-01 SK SK592-95A patent/SK279913B6/sk not_active IP Right Cessation
- 1994-09-01 CN CN94190728A patent/CN1082818C/zh not_active Expired - Lifetime
- 1994-09-01 ES ES94925612T patent/ES2148340T3/es not_active Expired - Lifetime
- 1994-09-01 SG SG1996002669A patent/SG52313A1/en unknown
-
1995
- 1995-04-28 NO NO19951639A patent/NO312227B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100221045B1 (ko) | 1999-09-15 |
| CN1082818C (zh) | 2002-04-17 |
| EP0667166B1 (en) | 2000-08-16 |
| KR950703998A (ko) | 1995-11-17 |
| EP0667166A4 (en) | 1995-11-02 |
| WO1995006482A1 (en) | 1995-03-09 |
| DE69425552T2 (de) | 2001-04-19 |
| CZ284261B6 (cs) | 1998-10-14 |
| CA2148109C (en) | 1999-11-23 |
| SK279913B6 (sk) | 1999-05-07 |
| PL308748A1 (en) | 1995-08-21 |
| NO951639D0 (no) | 1995-04-28 |
| ATE195431T1 (de) | 2000-09-15 |
| CA2148109A1 (en) | 1995-03-09 |
| NO951639L (no) | 1995-06-30 |
| ES2148340T3 (es) | 2000-10-16 |
| JP3045179B2 (ja) | 2000-05-29 |
| US5612327A (en) | 1997-03-18 |
| SG52313A1 (en) | 1998-09-28 |
| CN1114824A (zh) | 1996-01-10 |
| DE69425552D1 (de) | 2000-09-21 |
| NO312227B1 (no) | 2002-04-15 |
| SK59295A3 (en) | 1995-12-06 |
| PT667166E (pt) | 2001-02-28 |
| PL175492B1 (pl) | 1999-01-29 |
| CZ113295A3 (en) | 1995-11-15 |
| EP0667166A1 (en) | 1995-08-16 |
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