DK0667918T3 - Ikke-radioaktivt hybridiseringsassay og -sæt - Google Patents
Ikke-radioaktivt hybridiseringsassay og -sætInfo
- Publication number
- DK0667918T3 DK0667918T3 DK92924354T DK92924354T DK0667918T3 DK 0667918 T3 DK0667918 T3 DK 0667918T3 DK 92924354 T DK92924354 T DK 92924354T DK 92924354 T DK92924354 T DK 92924354T DK 0667918 T3 DK0667918 T3 DK 0667918T3
- Authority
- DK
- Denmark
- Prior art keywords
- kit
- hybridization assay
- radioactive hybridization
- radioactive
- hybrid
- Prior art date
Links
- 238000003556 assay Methods 0.000 title abstract 2
- 238000009396 hybridization Methods 0.000 title abstract 2
- 239000000523 sample Substances 0.000 abstract 2
- 241000701806 Human papillomavirus Species 0.000 abstract 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 230000009395 genetic defect Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 239000002853 nucleic acid probe Substances 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 230000002285 radioactive effect Effects 0.000 abstract 1
- 239000007790 solid phase Substances 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/708—Specific hybridization probes for papilloma
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/30—Oligonucleotides characterised by their secondary structure
- C12Q2525/301—Hairpin oligonucleotides
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79258591A | 1991-11-14 | 1991-11-14 | |
| PCT/US1992/009604 WO1993010263A1 (en) | 1991-11-14 | 1992-11-12 | Non-radioactive hybridization assay and kit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0667918T3 true DK0667918T3 (da) | 2000-06-05 |
Family
ID=25157398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92924354T DK0667918T3 (da) | 1991-11-14 | 1992-11-12 | Ikke-radioaktivt hybridiseringsassay og -sæt |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6228578B1 (da) |
| EP (1) | EP0667918B1 (da) |
| JP (1) | JP3091492B2 (da) |
| AT (1) | ATE189831T1 (da) |
| AU (1) | AU673813B2 (da) |
| DE (1) | DE69230693T2 (da) |
| DK (1) | DK0667918T3 (da) |
| ES (1) | ES2145750T3 (da) |
| FI (1) | FI112095B (da) |
| GR (1) | GR3033345T3 (da) |
| WO (1) | WO1993010263A1 (da) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5981179A (en) * | 1991-11-14 | 1999-11-09 | Digene Diagnostics, Inc. | Continuous amplification reaction |
| US6225053B1 (en) * | 1997-12-12 | 2001-05-01 | Digene Corporation | Detection of hepatitis B virus |
| WO1999031273A2 (en) * | 1997-12-12 | 1999-06-24 | Digene Corporation | Universal collection medium |
| US6686151B1 (en) * | 1998-02-06 | 2004-02-03 | Digene Corporation | Immunological detection of RNA:DNA hybrids on microarrays |
| US5994079A (en) * | 1998-02-06 | 1999-11-30 | Digene Corporation | Direct detection of RNA mediated by reverse transcriptase lacking RNAse H function |
| US7399589B2 (en) | 1998-02-06 | 2008-07-15 | Digene Corporation | Immunological detection of RNA:DNA hybrids on microarrays |
| AU764964B2 (en) * | 1998-11-23 | 2003-09-04 | Usamriid | Purification method and apparatus |
| US6723505B1 (en) * | 1999-08-13 | 2004-04-20 | Nye Colifast As | Method for identification of the indicators of contamination in liquid samples |
| US20040115692A1 (en) * | 2000-04-03 | 2004-06-17 | Cytyc Corporation | Methods, compositions and apparatuses for detecting a target in a preservative solution |
| US7439016B1 (en) * | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
| US7601497B2 (en) | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
| US7494817B2 (en) * | 2000-09-06 | 2009-02-24 | Transnet Yx, Inc. | Methods for genotype screening using magnetic particles |
| WO2002059137A1 (en) * | 2000-11-03 | 2002-08-01 | Isis Pharmaceuticals, Inc. | Nuclease-based method for detecting and quantitating oligonucleotides |
| US9261460B2 (en) | 2002-03-12 | 2016-02-16 | Enzo Life Sciences, Inc. | Real-time nucleic acid detection processes and compositions |
| US20050123913A1 (en) * | 2001-08-30 | 2005-06-09 | Emory University | Human mitochondrial dna polymorphisms, haplogroups, associations with physiological conditions, and genotyping arrays |
| CA2356540A1 (en) * | 2001-08-30 | 2003-02-28 | Emory University | Expressed dna sequences involved in mitochondrial functions |
| KR20030049802A (ko) * | 2001-12-17 | 2003-06-25 | 권윤정 | 바이오 칩에서 프로브와 시료 핵산의 혼성화 여부를 효소반응으로 구별하는 방법 |
| US9353405B2 (en) | 2002-03-12 | 2016-05-31 | Enzo Life Sciences, Inc. | Optimized real time nucleic acid detection processes |
| US7166478B2 (en) * | 2002-03-12 | 2007-01-23 | Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc. | Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses |
| US20030175828A1 (en) * | 2002-03-15 | 2003-09-18 | Lazar James G. | Signal amplification by Hybrid Capture |
| US20030224370A1 (en) * | 2002-05-31 | 2003-12-04 | William Rassman | Method and apparatus for recognizing molecular compounds |
| HUE033832T2 (en) | 2002-11-15 | 2018-01-29 | Idenix Pharmaceuticals Llc | 2'-methyl nucleosides in combination with interferon and Flaviviridae mutation |
| WO2004106357A1 (en) * | 2003-05-28 | 2004-12-09 | Maven Technologies, Llc | Method and apparatus for recognizing molecular compounds |
| US20060189893A1 (en) * | 2005-01-06 | 2006-08-24 | Diamics, Inc. | Systems and methods for detecting abnormal cells |
| US20060161076A1 (en) * | 2005-01-06 | 2006-07-20 | Diamics, Inc. | Systems and methods for collection of cell clusters |
| WO2006096727A2 (en) * | 2005-03-07 | 2006-09-14 | Cellay Llc | Methods for detecting integrated dna |
| US20070037174A1 (en) * | 2005-08-12 | 2007-02-15 | Rampal Jang B | Chemiluminescent generated fluorescent labeling |
| US7972776B2 (en) * | 2005-11-15 | 2011-07-05 | Oncohealth Corporation | Protein chips for HPV detection |
| US7732166B2 (en) * | 2005-11-15 | 2010-06-08 | Oncohealth Corporation | Detection method for human pappilomavirus (HPV) and its application in cervical cancer |
| US20080125333A1 (en) * | 2006-05-31 | 2008-05-29 | Antara Biosciences Inc. | Devices and kits for detecting one or more target agents |
| US8968995B2 (en) * | 2008-11-12 | 2015-03-03 | Oncohealth Corp. | Detection, screening, and diagnosis of HPV-associated cancers |
| US20100003704A1 (en) * | 2008-06-13 | 2010-01-07 | Shuling Cheng | IN SITU detection of early stages and late stages HPV infection |
| EP2115160B1 (en) * | 2007-02-23 | 2016-11-09 | Panagene, Inc. | Methods for increasing efficiency or specificity of hybridization between pna probes immobilized on support and target nucleic acids |
| JP2011518333A (ja) * | 2008-04-17 | 2011-06-23 | キアジェン ゲイサーズバーグ インコーポレイテッド | 標的核酸の存在を判別するための合成プローブを用いた組成物、方法、およびキット |
| WO2009129558A1 (en) | 2008-04-24 | 2009-10-29 | Newsouth Innovations Pty Limited | Cyanobacteria saxitoxin gene cluster and detection of cyanotoxic organisms |
| WO2010062546A1 (en) * | 2008-10-27 | 2010-06-03 | Qiagen Gaithersburg Inc. | Fast results hybrid capture assay on an automated platform |
| WO2010078574A1 (en) | 2009-01-05 | 2010-07-08 | Afl Telecommunications Llc | Universal mounting bracket |
| JP6108661B2 (ja) * | 2009-01-28 | 2017-04-05 | キアジェン ゲイサーズバーグ インコーポレイテッド | 配列特異的な大量試料調製方法およびアッセイ法 |
| EP2425019B1 (en) | 2009-05-01 | 2014-03-19 | QIAGEN Gaithersburg, Inc. | A non-target amplification method for detection of rna splice-forms in a sample |
| EP2427763A4 (en) | 2009-05-07 | 2013-08-21 | Oncohealth Corp | IDENTIFICATION OF A HIGH CIN2 DEGREE FOR THE DETECTION OF EARLY AND LATE TADIES AND FOR THE SCREENING AND DIAGNOSIS OF HUMAN PAPILLOMA (HPV) AND ASSOCIATED CANCER DISORDERS |
| JP5826752B2 (ja) | 2009-09-14 | 2015-12-02 | キアジェン ゲイサーズバーグ インコーポレイテッド | 細胞学用培地に固定された組織サンプルから核酸またはタンパク質を回収するための組成物および方法 |
| WO2011084598A1 (en) | 2010-01-08 | 2011-07-14 | Oncohealth Corporation | High throughput cell-based hpv immunoassays for diagnosis and screening of hpv-associated cancers |
| CA2787781A1 (en) * | 2010-01-29 | 2011-08-04 | Qiagen Gaithersburg, Inc. | Method of determining and confirming the presence of an hpv in a sample |
| CA2787924A1 (en) | 2010-01-29 | 2011-08-04 | Qiagen Gaithersburg, Inc. | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
| US20120301886A1 (en) * | 2010-02-26 | 2012-11-29 | Michael Farrell | Polytag probes |
| JP2013528049A (ja) | 2010-05-19 | 2013-07-08 | キアゲン ガイサーズバーグ アイエヌシー． | 核酸の配列特異的な精製及び多重分析のための方法及び組成物 |
| JP6153866B2 (ja) | 2010-05-25 | 2017-06-28 | キアゲン ガイサーズバーグ アイエヌシー． | 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ |
| CN103597095B (zh) | 2011-02-24 | 2016-08-17 | 奇亚根盖瑟斯堡股份有限公司 | 用于检测hpv核酸的材料和方法 |
| WO2013067399A1 (en) | 2011-11-03 | 2013-05-10 | Qiagen Gaithersburg, Inc. | Materials and method for immobilizing, isolating, and concentrating cells using carboxylated surfaces |
| DE102015203606C5 (de) | 2014-02-28 | 2023-12-21 | Gen-Probe Incorporated | Verfahren zur Isolierung von Nukleinsäure von zytologischen Proben in flüssigen Konservierungsmitteln, die Formaldehyd enthalten |
| EP3670664B1 (en) | 2014-02-28 | 2022-09-07 | Gen-Probe Incorporated | Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde |
| US10356478B2 (en) * | 2015-01-08 | 2019-07-16 | The Directv Group, Inc. | Systems and methods for spotted advertising and control of corresponding user interfaces and transactions via user receiving devices and mobile devices |
| JP7056143B2 (ja) * | 2016-12-27 | 2022-04-19 | 東洋紡株式会社 | 免疫学的測定用組成物および免疫学的測定方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4732847A (en) | 1981-06-09 | 1988-03-22 | University Of Hawaii | Monoclonal antibodies for DNA-RNA hybrid complexes and their uses |
| US4623627A (en) | 1983-08-19 | 1986-11-18 | Cetus Corporation | Monoclonal antibody having specificity for the double-stranded conformation of native DNA and diagnostic methods using same |
| EP0146039A3 (en) * | 1983-12-12 | 1986-08-27 | Miles Inc. | Hybridization assay with immobilization of hybrids by antihybrid binding |
| US4743535A (en) | 1984-11-07 | 1988-05-10 | Miles Inc. | Hybridization assay employing labeled probe and anti-hybrid |
| ZA853756B (en) | 1984-06-01 | 1986-01-29 | Miles Lab | Nucleic acid hybridization assay employing immobilized rna probes |
| CA1253777A (en) | 1984-06-01 | 1989-05-09 | Robert J. Carrico | Nucleic acid hybridization assay employing immobilized rna probes |
| US4563417A (en) | 1984-08-31 | 1986-01-07 | Miles Laboratories, Inc. | Nucleic acid hybridization assay employing antibodies to intercalation complexes |
| US4965188A (en) * | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
| AU558846B2 (en) * | 1985-06-21 | 1987-02-12 | Miles Laboratories Inc. | Solid-phase hydridization assay using anti-hybrid antibodies |
| US4968602A (en) * | 1986-03-05 | 1990-11-06 | Molecular Diagnostics, Inc. | Solution-phase single hybridization assay for detecting polynucleotide sequences |
| GB8712646D0 (en) * | 1987-05-29 | 1987-07-01 | Clayton Found Res | Structural evidence |
| JPH03503476A (ja) * | 1987-07-22 | 1991-08-08 | インペリアル キャンサー リサーチ テクノロジー，リミテッド | 消化方法 |
-
1992
- 1992-11-12 ES ES92924354T patent/ES2145750T3/es not_active Expired - Lifetime
- 1992-11-12 AT AT92924354T patent/ATE189831T1/de active
- 1992-11-12 AU AU30689/92A patent/AU673813B2/en not_active Expired
- 1992-11-12 JP JP05509340A patent/JP3091492B2/ja not_active Expired - Lifetime
- 1992-11-12 DK DK92924354T patent/DK0667918T3/da active
- 1992-11-12 EP EP92924354A patent/EP0667918B1/en not_active Expired - Lifetime
- 1992-11-12 WO PCT/US1992/009604 patent/WO1993010263A1/en not_active Ceased
- 1992-11-12 DE DE69230693T patent/DE69230693T2/de not_active Expired - Lifetime
-
1994
- 1994-01-18 US US08/183,154 patent/US6228578B1/en not_active Expired - Lifetime
- 1994-05-13 FI FI942239A patent/FI112095B/fi not_active IP Right Cessation
-
2000
- 2000-04-26 GR GR20000401030T patent/GR3033345T3/el unknown
-
2001
- 2001-05-07 US US09/850,041 patent/US20020012936A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU3068992A (en) | 1993-06-15 |
| FI942239A0 (fi) | 1994-05-13 |
| AU673813B2 (en) | 1996-11-28 |
| US6228578B1 (en) | 2001-05-08 |
| WO1993010263A1 (en) | 1993-05-27 |
| EP0667918A1 (en) | 1995-08-23 |
| DE69230693D1 (de) | 2000-03-23 |
| US20020012936A1 (en) | 2002-01-31 |
| EP0667918B1 (en) | 2000-02-16 |
| FI942239L (fi) | 1994-07-06 |
| JP3091492B2 (ja) | 2000-09-25 |
| FI112095B (fi) | 2003-10-31 |
| ES2145750T3 (es) | 2000-07-16 |
| ATE189831T1 (de) | 2000-03-15 |
| GR3033345T3 (en) | 2000-09-29 |
| JPH07505759A (ja) | 1995-06-29 |
| DE69230693T2 (de) | 2000-06-15 |
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