DK0674512T3 - Anvendelse af riluzol ved behandling af neurologiske skader knyttet til traumer - Google Patents
Anvendelse af riluzol ved behandling af neurologiske skader knyttet til traumerInfo
- Publication number
- DK0674512T3 DK0674512T3 DK94902019.2T DK94902019T DK0674512T3 DK 0674512 T3 DK0674512 T3 DK 0674512T3 DK 94902019 T DK94902019 T DK 94902019T DK 0674512 T3 DK0674512 T3 DK 0674512T3
- Authority
- DK
- Denmark
- Prior art keywords
- riluzole
- treatment
- pct
- trauma
- damage associated
- Prior art date
Links
- FTALBRSUTCGOEG-UHFFFAOYSA-N Riluzole Chemical compound C1=C(OC(F)(F)F)C=C2SC(N)=NC2=C1 FTALBRSUTCGOEG-UHFFFAOYSA-N 0.000 title abstract 2
- 208000014674 injury Diseases 0.000 title abstract 2
- 230000000926 neurological effect Effects 0.000 title abstract 2
- 229960004181 riluzole Drugs 0.000 title abstract 2
- 230000008733 trauma Effects 0.000 title 1
- 208000020339 Spinal injury Diseases 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000008736 traumatic injury Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Data Exchanges In Wide-Area Networks (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9215148A FR2699077B1 (fr) | 1992-12-16 | 1992-12-16 | Application d'anticonvulsivants dans le traitement de lésions neurologiques liées à des traumatismes. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0674512T3 true DK0674512T3 (da) | 1998-05-25 |
Family
ID=9436652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94902019.2T DK0674512T3 (da) | 1992-12-16 | 1993-12-10 | Anvendelse af riluzol ved behandling af neurologiske skader knyttet til traumer |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5830907A (da) |
| EP (3) | EP0674512B1 (da) |
| JP (3) | JP3712239B2 (da) |
| KR (3) | KR100298808B1 (da) |
| AT (1) | ATE164067T1 (da) |
| AU (3) | AU678795B2 (da) |
| CA (3) | CA2151601A1 (da) |
| CZ (3) | CZ154695A3 (da) |
| DE (1) | DE69317578T2 (da) |
| DK (1) | DK0674512T3 (da) |
| ES (1) | ES2113635T3 (da) |
| FR (1) | FR2699077B1 (da) |
| GR (1) | GR3026403T3 (da) |
| HU (3) | HUT71839A (da) |
| IL (3) | IL108051A (da) |
| MX (3) | MX9307883A (da) |
| NO (3) | NO952228L (da) |
| PL (3) | PL309348A1 (da) |
| RU (1) | RU2142800C1 (da) |
| SK (3) | SK279759B6 (da) |
| UA (1) | UA41906C2 (da) |
| WO (3) | WO1994013298A1 (da) |
| ZA (3) | ZA939401B (da) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2700117B1 (fr) * | 1993-01-07 | 1995-02-03 | Rhone Poulenc Rorer Sa | Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens. |
| GB9424766D0 (en) * | 1994-12-07 | 1995-02-08 | Wellcome Found | Pharmaceutical composition |
| FR2733684B1 (fr) | 1995-05-03 | 1997-05-30 | Cird Galderma | Utilisation de retinoides dans une composition cosmetique ou pour la fabrication d'une composition pharmaceutique |
| GB9512854D0 (en) * | 1995-06-23 | 1995-08-23 | Wellcome Found | Novel formulation |
| US20020022056A1 (en) | 1997-02-14 | 2002-02-21 | Burkhard Schlutermann | Oxacarbazepine film-coated tablets |
| CO4920215A1 (es) * | 1997-02-14 | 2000-05-29 | Novartis Ag | Tabletas de oxacarbazepina recubiertas de una pelicula y metodo para la produccion de estas formulaciones |
| DK1032575T3 (da) | 1997-09-05 | 2003-10-20 | Glaxo Group Ltd | 2,3-diaryl-pyrazol(1,5-b)pyridazinderivater, deres fremstilling og anvendelse som cyclooxygenase 2 (COX-2) inhibitor |
| GB9808015D0 (en) * | 1998-04-15 | 1998-06-17 | United Medical And Dental Scho | Protection of the nervous system from the effects of inflammatory disease |
| US6150423A (en) * | 1998-10-15 | 2000-11-21 | Phoenix Scientific, Inc. | Propofol-based anesthetic and method of making same |
| FR2787028B1 (fr) | 1998-12-15 | 2002-10-18 | Aventis Pharma Sa | Utilisation du riluzole dans le traitement des traumatismes acoustiques |
| JP2002543131A (ja) * | 1999-04-29 | 2002-12-17 | センター ナショナル デ ラ レシェルシェ サイエンティフィック(シーエヌアールエス) | 大動脈クロスクランピングが原因の虚血性脊髄損傷の防止方法 |
| GB9925962D0 (en) * | 1999-11-02 | 1999-12-29 | Novartis Ag | Organic compounds |
| GB9930058D0 (en) * | 1999-12-20 | 2000-02-09 | Novartis Ag | Organic compounds |
| RU2240113C1 (ru) * | 2003-01-23 | 2004-11-20 | Государственное образовательное учреждение высшего профессионального образования Московская медицинская академия им. И.М.Сеченова | Способ экстренной медикаментозной помощи при острой травме спинного мозга |
| US20060252745A1 (en) | 2005-05-06 | 2006-11-09 | Almeida Jose L D | Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use |
| EP1924326B1 (en) | 2005-08-25 | 2016-10-12 | Steven Michael Weiss | Reducing myocardial damage and the incidence of arrhythmia arising from loss, reduction or interruption in coronary blood flow |
| GB0700773D0 (en) | 2007-01-15 | 2007-02-21 | Portela & Ca Sa | Drug therapies |
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| US10322114B2 (en) | 2017-07-31 | 2019-06-18 | Above And Beyond Nb, Llc | Formulation of a riluzole solution with beta-cyclodextrins |
| WO2019108594A1 (en) * | 2017-11-28 | 2019-06-06 | University Of Houston System | Liquid formulations of riluzole for oral and intravenous use |
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Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK153787C (da) * | 1979-06-01 | 1989-01-16 | Wellcome Found | Analogifremgangsmaade til fremstilling af substituerede 3,5-diamino-6-phenyl-1,2,4-triaziner og alfa-cyanobenzyliden-aminoguanidinforbindelser til anvendelse som mellemprodukter herved |
| FR2492258A1 (fr) * | 1980-10-17 | 1982-04-23 | Pharmindustrie | Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole |
| US4431641A (en) * | 1980-10-17 | 1984-02-14 | Ciba-Geigy Corporation | Pharmaceutical compositions having antiepileptic and antineuralgic action |
| GB8613183D0 (en) * | 1986-05-30 | 1986-07-02 | Wellcome Found | Triazine salt |
| US4826860A (en) * | 1987-03-16 | 1989-05-02 | Warner-Lambert Company | Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents |
| US4918090A (en) * | 1988-01-25 | 1990-04-17 | Warner-Lambert Company | Substituted 2-aminbenzothiazoles and derivatives useful as cerebrovascular agents |
| US5240948A (en) * | 1989-12-13 | 1993-08-31 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | 3-(3-alkylthiopropyl)benzothiazoline derivatives, their preparation and the medicament containing them |
| GB9012312D0 (en) * | 1990-06-01 | 1990-07-18 | Wellcome Found | Pharmacologically active cns compounds |
| WO1992014697A1 (en) * | 1991-02-08 | 1992-09-03 | Cambridge Neuroscience, Inc. | Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers |
| FR2688138B1 (fr) * | 1992-03-06 | 1995-05-05 | Rhone Poulenc Rorer Sa | Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique. |
-
1992
- 1992-12-16 FR FR9215148A patent/FR2699077B1/fr not_active Expired - Fee Related
-
1993
- 1993-12-10 AU AU56540/94A patent/AU678795B2/en not_active Ceased
- 1993-12-10 CA CA002151601A patent/CA2151601A1/fr not_active Abandoned
- 1993-12-10 CZ CZ951546A patent/CZ154695A3/cs unknown
- 1993-12-10 CZ CZ951545A patent/CZ284420B6/cs not_active IP Right Cessation
- 1993-12-10 CA CA002151604A patent/CA2151604C/fr not_active Expired - Fee Related
- 1993-12-10 JP JP51388094A patent/JP3712239B2/ja not_active Expired - Fee Related
- 1993-12-10 KR KR1019950702460A patent/KR100298808B1/ko not_active Expired - Fee Related
- 1993-12-10 DK DK94902019.2T patent/DK0674512T3/da active
- 1993-12-10 PL PL93309348A patent/PL309348A1/xx unknown
- 1993-12-10 WO PCT/FR1993/001228 patent/WO1994013298A1/fr not_active Ceased
- 1993-12-10 JP JP6513878A patent/JPH08504428A/ja active Pending
- 1993-12-10 SK SK786-95A patent/SK279759B6/sk not_active IP Right Cessation
- 1993-12-10 PL PL93309346A patent/PL309346A1/xx unknown
- 1993-12-10 SK SK785-95A patent/SK78595A3/sk unknown
- 1993-12-10 EP EP94902019A patent/EP0674512B1/fr not_active Expired - Lifetime
- 1993-12-10 SK SK787-95A patent/SK78795A3/sk unknown
- 1993-12-10 JP JP6513879A patent/JPH08504429A/ja active Pending
- 1993-12-10 HU HU9501752A patent/HUT71839A/hu unknown
- 1993-12-10 WO PCT/FR1993/001227 patent/WO1994013296A1/fr not_active Ceased
- 1993-12-10 KR KR1019950702459A patent/KR950703968A/ko not_active Withdrawn
- 1993-12-10 CA CA002151603A patent/CA2151603A1/fr not_active Abandoned
- 1993-12-10 PL PL93309347A patent/PL309347A1/xx unknown
- 1993-12-10 ES ES94902019T patent/ES2113635T3/es not_active Expired - Lifetime
- 1993-12-10 EP EP94902802A patent/EP0674518A1/fr not_active Withdrawn
- 1993-12-10 DE DE69317578T patent/DE69317578T2/de not_active Expired - Lifetime
- 1993-12-10 AU AU57020/94A patent/AU5702094A/en not_active Abandoned
- 1993-12-10 WO PCT/FR1993/001229 patent/WO1994013288A1/fr not_active Ceased
- 1993-12-10 KR KR1019950702458A patent/KR950703965A/ko not_active Withdrawn
- 1993-12-10 EP EP94902018A patent/EP0674520A1/fr not_active Ceased
- 1993-12-10 CZ CZ951547A patent/CZ154795A3/cs unknown
- 1993-12-10 AU AU56539/94A patent/AU5653994A/en not_active Abandoned
- 1993-12-10 RU RU95114405A patent/RU2142800C1/ru not_active IP Right Cessation
- 1993-12-10 AT AT94902019T patent/ATE164067T1/de active
- 1993-12-10 UA UA95062798A patent/UA41906C2/uk unknown
- 1993-12-10 HU HU9501753A patent/HUT71812A/hu unknown
- 1993-12-10 US US08/424,529 patent/US5830907A/en not_active Expired - Lifetime
- 1993-12-10 HU HU9501751A patent/HU217133B/hu not_active IP Right Cessation
- 1993-12-13 MX MX9307883A patent/MX9307883A/es unknown
- 1993-12-13 MX MX9307882A patent/MX9307882A/es not_active Application Discontinuation
- 1993-12-13 MX MX9307884A patent/MX9307884A/es unknown
- 1993-12-15 ZA ZA939401A patent/ZA939401B/xx unknown
- 1993-12-15 ZA ZA939400A patent/ZA939400B/xx unknown
- 1993-12-15 ZA ZA939399A patent/ZA939399B/xx unknown
- 1993-12-16 IL IL10805193A patent/IL108051A/en not_active IP Right Cessation
- 1993-12-16 IL IL10805293A patent/IL108052A0/xx unknown
- 1993-12-16 IL IL10805393A patent/IL108053A0/xx unknown
-
1995
- 1995-06-06 NO NO952228A patent/NO952228L/no unknown
- 1995-06-06 NO NO952229A patent/NO952229L/no unknown
- 1995-06-06 NO NO952230A patent/NO307027B1/no not_active IP Right Cessation
-
1998
- 1998-03-19 GR GR970403094T patent/GR3026403T3/el unknown
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