DK0678515T3 - Fremgangsmåde og mellemprodukter til fremstilling af 5-oxaspiro[2.4]heptan-on - Google Patents
Fremgangsmåde og mellemprodukter til fremstilling af 5-oxaspiro[2.4]heptan-onInfo
- Publication number
- DK0678515T3 DK0678515T3 DK95105830T DK95105830T DK0678515T3 DK 0678515 T3 DK0678515 T3 DK 0678515T3 DK 95105830 T DK95105830 T DK 95105830T DK 95105830 T DK95105830 T DK 95105830T DK 0678515 T3 DK0678515 T3 DK 0678515T3
- Authority
- DK
- Denmark
- Prior art keywords
- oxaspiro
- heptanone
- intermediates
- preparation
- formula
- Prior art date
Links
- ICSLSSNYRZUGGI-UHFFFAOYSA-N 5-oxaspiro[2.4]heptan-2-one Chemical compound O=C1CC11COCC1 ICSLSSNYRZUGGI-UHFFFAOYSA-N 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- FQVIUCMKUIUWKC-UHFFFAOYSA-N 2-[3-(hydroxymethyl)oxetan-3-yl]acetonitrile Chemical compound N#CCC1(CO)COC1 FQVIUCMKUIUWKC-UHFFFAOYSA-N 0.000 abstract 2
- CTWOGRWCMPHOMQ-UHFFFAOYSA-N 4,4-bis(bromomethyl)oxolan-2-one Chemical compound BrCC1(CBr)COC(=O)C1 CTWOGRWCMPHOMQ-UHFFFAOYSA-N 0.000 abstract 1
- VDDTXNQOEDQFSZ-UHFFFAOYSA-N 5-oxaspiro[2.4]heptan-6-one Chemical compound C1OC(=O)CC11CC1 VDDTXNQOEDQFSZ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/11—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton
- C07C255/12—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Furan Compounds (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH123094 | 1994-04-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0678515T3 true DK0678515T3 (da) | 1998-11-02 |
Family
ID=4205533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95105830T DK0678515T3 (da) | 1994-04-21 | 1995-04-19 | Fremgangsmåde og mellemprodukter til fremstilling af 5-oxaspiro[2.4]heptan-on |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5486622A (da) |
| EP (1) | EP0678515B1 (da) |
| JP (1) | JPH07291957A (da) |
| AT (1) | ATE168110T1 (da) |
| CA (1) | CA2145735A1 (da) |
| DE (1) | DE59502722D1 (da) |
| DK (1) | DK0678515T3 (da) |
| ES (1) | ES2120098T3 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103936703A (zh) * | 2013-01-17 | 2014-07-23 | 上海朴颐化学科技有限公司 | 一种5-氧杂螺[2,4]庚-6-酮及其中间体的制备方法 |
| CN103467276B (zh) * | 2013-09-13 | 2015-05-06 | 天津速研医药科技有限公司 | 一种孟鲁司特钠侧链关键中间体的合成方法 |
| JP7675618B2 (ja) * | 2021-10-28 | 2025-05-13 | 株式会社クラレ | ２－メチレン－１，３－プロパンジオールの製造方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0480717T3 (da) * | 1990-10-12 | 1999-02-08 | Merck Frosst Canada Inc | Umættede hydroxyalkylquinolinsyrer som leukotrienantagonister |
-
1995
- 1995-03-28 CA CA002145735A patent/CA2145735A1/en not_active Abandoned
- 1995-04-05 US US08/417,250 patent/US5486622A/en not_active Expired - Fee Related
- 1995-04-14 JP JP7089824A patent/JPH07291957A/ja active Pending
- 1995-04-19 DE DE59502722T patent/DE59502722D1/de not_active Expired - Fee Related
- 1995-04-19 AT AT95105830T patent/ATE168110T1/de not_active IP Right Cessation
- 1995-04-19 ES ES95105830T patent/ES2120098T3/es not_active Expired - Lifetime
- 1995-04-19 EP EP95105830A patent/EP0678515B1/de not_active Expired - Lifetime
- 1995-04-19 DK DK95105830T patent/DK0678515T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0678515A1 (de) | 1995-10-25 |
| US5486622A (en) | 1996-01-23 |
| CA2145735A1 (en) | 1995-10-22 |
| DE59502722D1 (de) | 1998-08-13 |
| JPH07291957A (ja) | 1995-11-07 |
| ES2120098T3 (es) | 1998-10-16 |
| ATE168110T1 (de) | 1998-07-15 |
| EP0678515B1 (de) | 1998-07-08 |
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