DK0688866T3 - Termostabilt, trehalosefrigørende enzym og fremstillingen og anvendelserne deraf - Google Patents

Termostabilt, trehalosefrigørende enzym og fremstillingen og anvendelserne deraf

Info

Publication number: DK0688866T3
Authority: DK; Denmark
Prior art keywords: trehalose; atcc; thermostable; preparation; releasing enzyme
Prior art date: 1994-06-25

Application number

DK95304425T

Other languages

English (en)

Inventor

Shouji Ikegami

Michio Kubota

Toshiyuki Sugimoto

Toshio Miyake

Original Assignee

Hayashibara Biochem Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-06-25

Filing date

1995-06-23

Publication date

1999-06-07

1995-06-23 Application filed by Hayashibara Biochem Lab filed Critical Hayashibara Biochem Lab

1999-06-07 Application granted granted Critical

1999-06-07 Publication of DK0688866T3 publication Critical patent/DK0688866T3/da

Links

HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 title abstract 3
102000004190 Enzymes Human genes 0.000 title abstract 3
108090000790 Enzymes Proteins 0.000 title abstract 3
HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 title abstract 3
HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 title abstract 3
238000002360 preparation method Methods 0.000 title abstract 2
125000000647 trehalose group Chemical group 0.000 abstract 2
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
241000205098 Sulfolobus acidocaldarius Species 0.000 abstract 1
241000205091 Sulfolobus solfataricus Species 0.000 abstract 1
150000001720 carbohydrates Chemical class 0.000 abstract 1
239000002537 cosmetic Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
235000013305 food Nutrition 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
125000003147 glycosyl group Chemical group 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
244000005700 microbiome Species 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
238000006116 polymerization reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01141—4-Alpha-D-{(1->4)-alpha-D-glucano} trehalose trehalohydrolase (3.2.1.141)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/12—Disaccharides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Dermatology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oral & Maxillofacial Surgery (AREA)
Birds (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Cosmetics (AREA)
Enzymes And Modification Thereof (AREA)
Medicinal Preparation (AREA)
Confectionery (AREA)
Non-Alcoholic Beverages (AREA)
Bakery Products And Manufacturing Methods Therefor (AREA)
Meat, Egg Or Seafood Products (AREA)

DK95304425T 1994-06-25 1995-06-23 Termostabilt, trehalosefrigørende enzym og fremstillingen og anvendelserne deraf DK0688866T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP16612694		1994-06-25
JP10913095A JP3557277B2 (ja)	1994-06-25	1995-04-11	耐熱性トレハロース遊離酵素とその製造方法並びに用途

Publications (1)

Publication Number	Publication Date
DK0688866T3 true DK0688866T3 (da)	1999-06-07

Family

ID=26448918

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95304425T DK0688866T3 (da)	1994-06-25	1995-06-23	Termostabilt, trehalosefrigørende enzym og fremstillingen og anvendelserne deraf

Country Status (10)

Country	Link
US (2)	US5723327A (da)
EP (1)	EP0688866B1 (da)
JP (1)	JP3557277B2 (da)
KR (1)	KR100391376B1 (da)
AT (1)	ATE170920T1 (da)
AU (1)	AU694213B2 (da)
CA (1)	CA2151438C (da)
DE (1)	DE69504584T2 (da)
DK (1)	DK0688866T3 (da)
TW (1)	TW507008B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3557277B2 (ja) *	1994-06-25	2004-08-25	株式会社林原生物化学研究所	耐熱性トレハロース遊離酵素とその製造方法並びに用途
JP3662972B2 (ja) *	1994-06-27	2005-06-22	株式会社林原生物化学研究所	非還元性糖質とその製造方法並びに用途
JP3793590B2 (ja) *	1994-06-27	2006-07-05	株式会社林原生物化学研究所	非還元性糖質とその製造方法並びに用途
EP0693558B1 (en) *	1994-07-19	2002-12-04	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Trehalose and its production and use
JP3557289B2 (ja) *	1994-07-21	2004-08-25	株式会社林原生物化学研究所	非還元性糖質からトレハロースを遊離する組換え型耐熱性酵素
JP3557288B2 (ja) *	1994-07-21	2004-08-25	株式会社林原生物化学研究所	還元性澱粉糖から末端にトレハロース構造を有する非還元性糖質を生成する組換え型耐熱性酵素
NL9500292A (nl) *	1995-02-16	1996-10-01	Stichting Nl Instituut Voor Ko	Werkwijze voor omzetting van een zetmeelmateriaal, en daarvoor bruikbaar enzympreparaat.
JPH11116588A (ja)	1997-10-16	1999-04-27	Hayashibara Biochem Lab Inc	トレハロース及び糖アルコールの製造方法
JP4295840B2 (ja) *	1997-12-09	2009-07-15	株式会社林原生物化学研究所	血行改善剤
JP4203159B2 (ja)	1997-12-09	2008-12-24	株式会社林原生物化学研究所	神経機能調節剤
JP3958884B2 (ja)	1998-09-11	2007-08-15	株式会社林原生物化学研究所	非還元性糖質生成酵素及びトレハロース遊離酵素ならびに該酵素を用いる糖質の製造方法
JP2000262252A (ja)	1999-01-11	2000-09-26	Aoba Kasei Kk	タンパク質変性抑制剤、冷凍変性が抑制された擂潰食肉およびその製造方法ならびに練り製品の製造方法
JP4652540B2 (ja)	2000-03-02	2011-03-16	株式会社林原生物化学研究所	体臭抑制剤とその用途
AU781975B2 (en) *	2000-09-14	2005-06-23	Hayashibara Co., Ltd	Pharmaceutical composition for ophthalmic use
JP4982643B2 (ja) *	2000-09-14	2012-07-25	株式会社林原	眼科用医薬組成物
JP4754066B2 (ja)	2000-12-22	2011-08-24	株式会社林原生物化学研究所	抗関節障害剤
KR20060033723A (ko) *	2003-06-05	2006-04-19	카아길, 인코포레이팃드	트레할로스와 단백질의 음료 첨가제 혼합물
JP4601934B2 (ja) *	2003-10-06	2010-12-22	ナガセ医薬品株式会社	ユビデカレノン錠
CN1953755A (zh) *	2004-05-17	2007-04-25	株式会社林原生物化学研究所	强化接触水系环境的生物的生命活动和/或扩张生命活动适合区域的方法
EP1598428A1 (en)	2004-05-18	2005-11-23	Georg Dewald	Methods and kits to detect Hereditary angioedema type III
US8231925B2 (en) *	2004-08-20	2012-07-31	Cargill, Incorporated	Ingredient systems comprising trehalose, food products containing trehalose, and methods of making same
WO2006023812A1 (en) *	2004-08-20	2006-03-02	Cargill Incorporated	Ingredient systems comprising trehalose, food products containing trehalose, and methods of making same
JP5184768B2 (ja) *	2006-09-05	2013-04-17	株式会社林原	トレハロース高含有糖液の回収方法並びに結晶トレハロースの製造方法
BR112014006682B1 (pt)	2011-09-21	2021-03-16	Hayashibara Co., Ltd	composição particulada compreendendo di-hidrato de alfa, alfa-trealose cristalino e seu método de produção
EP3665275A1 (en) *	2017-08-08	2020-06-17	Novozymes A/S	Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
WO2020053808A1 (en)	2018-09-12	2020-03-19	Georg Dewald	Method of diagnosing vasoregulatory disorders
CN114032206A (zh) *	2021-11-29	2022-02-11	广东希普生物科技股份有限公司	一种酵母菌种子液的培养方法
CN114703159B (zh) *	2022-03-15	2023-05-26	林影	一种葡糖基转移酶突变体及其应用

Family Cites Families (13)

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JPS50154485A (da) *	1974-05-31	1975-12-12
JPS5823799A (ja) *	1981-08-03	1983-02-12	株式会社林原生物化学研究所	高純度マルト−スの製造方法
JPS5872598A (ja) *	1981-10-26	1983-04-30	Hayashibara Biochem Lab Inc	高純度イソマルト−スの製造方法
JPS58216695A (ja) *	1982-06-07	1983-12-16	Otsuka Shokuhin Kogyo Kk	トレハロ−スの製造方法
US4762857A (en) *	1986-05-30	1988-08-09	E. I. Du Pont De Nemours And Company	Trehalose as stabilizer and tableting excipient
US4839164A (en) *	1987-02-24	1989-06-13	Estee Lauder, Inc.	Trehalose containing cosmetic composition and method of using it
GB8715238D0 (en) *	1987-06-29	1987-08-05	Quadrant Bioresources Ltd	Food process
JP3134229B2 (ja)	1990-03-08	2001-02-13	株式会社林原生物化学研究所	ラクトスクロース高含有粉末の製造方法とその粉末の用途
JP2613000B2 (ja)	1992-11-30	1997-05-21	大倉工業株式会社	パーテイクルボードの製造方法
JP3168550B2 (ja) *	1992-12-02	2001-05-21	株式会社林原生物化学研究所	脱水剤およびそれを用いる含水物の脱水方法並びにその方法で得られる脱水物品
ATE182359T1 (de) *	1992-12-28	1999-08-15	Hayashibara Biochem Lab	Nichtreduzierendes saccharidbildendes enzym, und dessen herstellung und verwendungen
JP3559585B2 (ja) *	1993-06-03	2004-09-02	株式会社林原生物化学研究所	トレハロース遊離酵素とその製造方法並びに用途
JP3557277B2 (ja) *	1994-06-25	2004-08-25	株式会社林原生物化学研究所	耐熱性トレハロース遊離酵素とその製造方法並びに用途

1995
- 1995-04-11 JP JP10913095A patent/JP3557277B2/ja not_active Expired - Lifetime
- 1995-06-07 US US08/485,132 patent/US5723327A/en not_active Expired - Lifetime
- 1995-06-09 CA CA002151438A patent/CA2151438C/en not_active Expired - Lifetime
- 1995-06-13 TW TW084106021A patent/TW507008B/zh not_active IP Right Cessation
- 1995-06-20 KR KR1019950016450A patent/KR100391376B1/ko not_active Expired - Lifetime
- 1995-06-23 AT AT95304425T patent/ATE170920T1/de not_active IP Right Cessation
- 1995-06-23 DE DE69504584T patent/DE69504584T2/de not_active Expired - Lifetime
- 1995-06-23 AU AU23239/95A patent/AU694213B2/en not_active Expired
- 1995-06-23 EP EP95304425A patent/EP0688866B1/en not_active Expired - Lifetime
- 1995-06-23 DK DK95304425T patent/DK0688866T3/da active
1997
- 1997-07-03 US US08/888,158 patent/US6150153A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0688866B1 (en)	1998-09-09
DE69504584T2 (de)	1999-05-12
US6150153A (en)	2000-11-21
US5723327A (en)	1998-03-03
DE69504584D1 (de)	1998-10-15
AU2323995A (en)	1996-01-11
ATE170920T1 (de)	1998-09-15
KR960001112A (ko)	1996-01-25
EP0688866A1 (en)	1995-12-27
KR100391376B1 (ko)	2003-10-22
JPH0866187A (ja)	1996-03-12
AU694213B2 (en)	1998-07-16
CA2151438C (en)	2007-02-20
TW507008B (en)	2002-10-21
JP3557277B2 (ja)	2004-08-25
CA2151438A1 (en)	1995-12-26

Publication	Publication Date	Title
AU2323995A (en)	1996-01-11	Thermostable trehalose-releasing enzyme, and its preparationand uses
DE69535029D1 (de)	2006-07-20	Thermostabiles, nichtreduzierendes Saccharid-bildendes Enzym, seine Herstellung und seine Verwendungen
Scigelova et al.	1999	Glycosidases—a great synthetic tool
IL121712A (en)	2000-08-31	Process for preparing composition containing trehalose
KR940014777A (ko)	1994-07-19	비환원성 당질 생성 효소와 그 제조방법 및 용도
Kato et al.	1996	Purification and characterization of new trehalose-producing enzymes isolated from the hyperthermophilic archae, Sulfolobus solfataricus KM1
TSUJISAKA et al.	1993	Pullulan
KR950000723A (ko)	1995-01-03	비환원성 올리고당질 및 그 제조 방법과 용도
GB9116133D0 (en)	1991-09-11	Amylose granule and its preparation
Barker et al.	1953	Enzymic synthesis of polysaccharides
KR910016935A (ko)	1991-11-05	락토수크로오스 고함유 분말의 제조방법과 그 분말의 용도
EP0764720A4 (en)	1999-10-20	NOVEL TRANSFERASE AND AMYLASE, PROCESS FOR PRODUCING SUCH ENZYMES, USE, AND GENES ENCODING THE SAME
KR960001130A (ko)	1996-01-25	비환원성 당질과 그 제조 방법 및 용도
ES2059362T3 (es)	1994-11-16	Producto enzimatico de beta-amilasa, preparacion y su empleo.
Kato	1999	Trehalose production with a new enzymatic system from Sulfolobus solfataricus KM1
TH28359B (th)	1998-04-10	การผลิตและการใช้งานเอนไซม์ปลดปล่อยทรีฮาโลสที่ทนความร้อน
GR3036186T3 (en)	2001-10-31	Process for producing disaccharides and novel saccharides
Cui	1996	Studies on characterization of polysaccharide from Klebsiella oxytoca and enzymatic modification of selected polysaccharides
TH28359A (th)	1998-04-10	การผลิตและการใช้งานเอนไซม์ปลดปล่อยทรีฮาโลสที่ทน?ความร้อน
Schlecht	1986	Influence of cultivation temperature on the yield of biomass and of lipopolysaccharide of Salmonella S forms and R mutants. Chemical composition and antigenic properties of the lipopolysaccharide.
Ledingham	1968	Studies on bacterial α-amylases
HASHIMOTO	1997	Studies on Enzymatic Synthesis and Functions of a-Galactosides
KR880007718A (ko)	1988-08-29	개조된 세균성 알파-아밀라아제 효소와 그의 제조방법
JPH0133160B2 (da)	1989-07-12
KR870010179A (ko)	1987-11-30	탈분지 효소