DK0693073T3 - Bicykliske ansamyciner og deres anvendelse som antitumormidler - Google Patents

Bicykliske ansamyciner og deres anvendelse som antitumormidler

Info

Publication number
DK0693073T3
DK0693073T3 DK94913896T DK94913896T DK0693073T3 DK 0693073 T3 DK0693073 T3 DK 0693073T3 DK 94913896 T DK94913896 T DK 94913896T DK 94913896 T DK94913896 T DK 94913896T DK 0693073 T3 DK0693073 T3 DK 0693073T3
Authority
DK
Denmark
Prior art keywords
antitumor agents
ansamycins
bicyclic
bicyclic ansamycins
compounds
Prior art date
Application number
DK94913896T
Other languages
English (en)
Inventor
Rodney C Schnur
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0693073T3 publication Critical patent/DK0693073T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK94913896T 1993-04-07 1994-03-14 Bicykliske ansamyciner og deres anvendelse som antitumormidler DK0693073T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/044,521 US5387584A (en) 1993-04-07 1993-04-07 Bicyclic ansamycins
PCT/US1994/002546 WO1994022867A1 (en) 1993-04-07 1994-03-14 Bicyclic ansamycins and their use as antitumor agents

Publications (1)

Publication Number Publication Date
DK0693073T3 true DK0693073T3 (da) 1998-10-12

Family

ID=21932854

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94913896T DK0693073T3 (da) 1993-04-07 1994-03-14 Bicykliske ansamyciner og deres anvendelse som antitumormidler

Country Status (10)

Country Link
US (1) US5387584A (da)
EP (1) EP0693073B1 (da)
JP (1) JP2722280B2 (da)
AT (1) ATE166877T1 (da)
CA (1) CA2160137C (da)
DE (1) DE69410790T2 (da)
DK (1) DK0693073T3 (da)
ES (1) ES2116594T3 (da)
FI (1) FI106028B (da)
WO (1) WO1994022867A1 (da)

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US20050020557A1 (en) * 2003-05-30 2005-01-27 Kosan Biosciences, Inc. Method for treating diseases using HSP90-inhibiting agents in combination with enzyme inhibitors
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US7691838B2 (en) * 2003-05-30 2010-04-06 Kosan Biosciences Incorporated Method for treating diseases using HSP90-inhibiting agents in combination with antimitotics
US7241754B2 (en) * 2003-06-13 2007-07-10 Kosan Biosciences, Inc. 2-Desmethyl ansamycin compounds
CN100404029C (zh) * 2003-09-25 2008-07-23 中国医学科学院医药生物技术研究所 格尔德霉素（c-3559）在制备疱疹病毒生殖道感染药物中的应用
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JP5123429B2 (ja) * 2008-04-29 2013-01-23 ジョイアント ファーマスーティカルズ、インク． インドリン抗癌剤
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WO2011040421A1 (ja) 2009-09-29 2011-04-07 武田薬品工業株式会社 スクリーニング方法
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US4261989A (en) * 1979-02-19 1981-04-14 Kaken Chemical Co. Ltd. Geldanamycin derivatives and antitumor drug

Also Published As

Publication number Publication date
ATE166877T1 (de) 1998-06-15
DE69410790D1 (de) 1998-07-09
DE69410790T2 (de) 1998-10-01
EP0693073B1 (en) 1998-06-03
CA2160137A1 (en) 1994-10-13
ES2116594T3 (es) 1998-07-16
CA2160137C (en) 1999-02-09
JPH08503960A (ja) 1996-04-30
WO1994022867A1 (en) 1994-10-13
FI941580A0 (fi) 1994-04-06
FI106028B (fi) 2000-11-15
JP2722280B2 (ja) 1998-03-04
US5387584A (en) 1995-02-07
EP0693073A1 (en) 1996-01-24
FI941580L (fi) 1994-10-08

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