DK0693080T3 - Nye glucocorticoider - Google Patents

Nye glucocorticoider

Info

Publication number: DK0693080T3
Authority: DK; Denmark
Prior art keywords: pct; groups; radical; date oct; sec
Prior art date: 1993-04-07

Application number

DK94912531T

Other languages

English (en)

Inventor

Hans Joachim Zentel

Michael Tipert

Henry Laurent

Peter Esperling

Thomas Brumby

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-04-07

Filing date

1994-03-24

Publication date

1999-02-22

1994-03-24 Application filed by Schering Ag filed Critical Schering Ag

1999-02-22 Application granted granted Critical

1999-02-22 Publication of DK0693080T3 publication Critical patent/DK0693080T3/da

Links

239000003862 glucocorticoid Substances 0.000 title 1
229940037128 systemic glucocorticoids Drugs 0.000 title 1
KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Chemical compound CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 abstract 2
239000004215 Carbon black (E152) Substances 0.000 abstract 1
239000003470 adrenal cortex hormone Substances 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
RKHQGWMMUURILY-UHRZLXHJSA-N cortivazol Chemical group C([C@H]1[C@@H]2C[C@H]([C@]([C@@]2(C)C[C@H](O)[C@@H]1[C@@]1(C)C2)(O)C(=O)COC(C)=O)C)=C(C)C1=CC1=C2C=NN1C1=CC=CC=C1 RKHQGWMMUURILY-UHRZLXHJSA-N 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229930195733 hydrocarbon Natural products 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000004474 valine Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
General Chemical & Material Sciences (AREA)
Pain & Pain Management (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK94912531T 1993-04-07 1994-03-24 Nye glucocorticoider DK0693080T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4311987A DE4311987A1 (de)	1993-04-07	1993-04-07	Neue Glucocorticoide
PCT/EP1994/000937 WO1994022898A1 (de)	1993-04-07	1994-03-24	Neue glucocorticoide

Publications (1)

Publication Number	Publication Date
DK0693080T3 true DK0693080T3 (da)	1999-02-22

Family

ID=6485335

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94912531T DK0693080T3 (da)	1993-04-07	1994-03-24	Nye glucocorticoider

Country Status (10)

Country	Link
US (1)	US5616573A (da)
EP (1)	EP0693080B1 (da)
JP (1)	JPH08508727A (da)
AT (1)	ATE165366T1 (da)
AU (1)	AU696090B2 (da)
CA (1)	CA2158643A1 (da)
DE (2)	DE4311987A1 (da)
DK (1)	DK0693080T3 (da)
ES (1)	ES2118399T3 (da)
WO (1)	WO1994022898A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2167818A1 (en)	1993-08-02	1995-02-09	Robert George Whittaker	Therapeutic compound - fatty acid conjugates
US5952499A (en) *	1995-01-16	1999-09-14	Commonwealth Scientific And Industrial Research Organisation	Therapeutic compound-fatty acid conjugates
CA3042428A1 (en)	2016-11-08	2018-05-17	Regeneron Pharmaceuticals, Inc.	Steroids and protein-conjugates thereof
WO2018175173A1 (en) *	2017-03-21	2018-09-27	The Scripps Research Institute	Cu-and ni-catalyzed decarboxylative borylation reactions
KR20250008984A (ko)	2017-05-18	2025-01-16	리제너론 파마슈티칼스 인코포레이티드	사이클로덱스트린 단백질 약물 접합체
CA3247730A1 (en)	2017-11-07	2025-10-30	Regeneron Pharmaceuticals, Inc.	Hydrophilic linkers for antibody drug conjugates
MA50259A1 (fr) *	2018-01-08	2021-07-29	Regeneron Pharma	Stéroïdes et leurs conjugués-anticorps
WO2019217591A1 (en)	2018-05-09	2019-11-14	Regeneron Pharmaceuticals, Inc.	Anti-msr1 antibodies and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2546163B1 (fr) *	1983-05-16	1987-10-09	Centre Nat Rech Scient	Nouveaux derives acyles hydrosolubles de peptides ou d'amino-acides, leur preparation et leur application
US4997814A (en) *	1988-06-09	1991-03-05	Allelix Biopharmaceuticals, Inc.	Pharmaceutical compositions and use thereof in treating inflammation
JPH04273892A (ja) *	1991-02-27	1992-09-30	Kao Corp	新規な２１−置換ステロイド化合物
AU678961B2 (en) *	1991-11-22	1997-06-19	Alcon Laboratories, Inc.	Angiostatic steroids
WO1993023040A1 (en) *	1992-05-20	1993-11-25	Merck & Co., Inc.	17-ethers and thioethers of 4-aza-steroids
ATE198601T1 (de) *	1992-05-20	2001-01-15	Merck & Co Inc	Ester derivate von 4-aza-steroiden

1993
- 1993-04-07 DE DE4311987A patent/DE4311987A1/de not_active Withdrawn
1994
- 1994-03-24 ES ES94912531T patent/ES2118399T3/es not_active Expired - Lifetime
- 1994-03-24 AU AU65048/94A patent/AU696090B2/en not_active Ceased
- 1994-03-24 DK DK94912531T patent/DK0693080T3/da active
- 1994-03-24 EP EP94912531A patent/EP0693080B1/de not_active Expired - Lifetime
- 1994-03-24 WO PCT/EP1994/000937 patent/WO1994022898A1/de not_active Ceased
- 1994-03-24 AT AT94912531T patent/ATE165366T1/de not_active IP Right Cessation
- 1994-03-24 US US08/530,352 patent/US5616573A/en not_active Expired - Fee Related
- 1994-03-24 CA CA002158643A patent/CA2158643A1/en not_active Abandoned
- 1994-03-24 DE DE59405797T patent/DE59405797D1/de not_active Expired - Lifetime
- 1994-03-24 JP JP6521644A patent/JPH08508727A/ja active Pending

Also Published As

Publication number	Publication date
EP0693080A1 (de)	1996-01-24
ATE165366T1 (de)	1998-05-15
CA2158643A1 (en)	1994-10-13
JPH08508727A (ja)	1996-09-17
US5616573A (en)	1997-04-01
DE4311987A1 (de)	1994-10-13
AU6504894A (en)	1994-10-24
AU696090B2 (en)	1998-09-03
EP0693080B1 (de)	1998-04-22
ES2118399T3 (es)	1998-09-16
WO1994022898A1 (de)	1994-10-13
DE59405797D1 (de)	1998-05-28

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