DK0697461T3 - Rekombinant termostabilt enzym, som frigør trehalose fra ikke-reducerende saccharid - Google Patents

Rekombinant termostabilt enzym, som frigør trehalose fra ikke-reducerende saccharid

Info

Publication number: DK0697461T3
Authority: DK; Denmark
Prior art keywords: trehalose; liberates; thermostable enzyme; recombinant thermostable; reducing saccharide
Prior art date: 1994-07-21

Application number

DK95305100T

Other languages

English (en)

Inventor

Toshiyuki Sugimoto

Michio Kubota

Hitoshi Mitsuzumi

Original Assignee

Hayashibara Biochem Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-07-21

Filing date

1995-07-21

Publication date

1999-06-21

1995-07-21 Application filed by Hayashibara Biochem Lab filed Critical Hayashibara Biochem Lab

1999-06-21 Application granted granted Critical

1999-06-21 Publication of DK0697461T3 publication Critical patent/DK0697461T3/da

Links

HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 title abstract 3
102000004190 Enzymes Human genes 0.000 title abstract 3
108090000790 Enzymes Proteins 0.000 title abstract 3
HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 title abstract 3
HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 title abstract 3
150000001720 carbohydrates Chemical class 0.000 title abstract 2
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
238000006116 polymerization reaction Methods 0.000 abstract 1
125000000647 trehalose group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01141—4-Alpha-D-{(1->4)-alpha-D-glucano} trehalose trehalohydrolase (3.2.1.141)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/12—Disaccharides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01064—Alpha,alpha-trehalose phosphorylase (2.4.1.64)
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Enzymes And Modification Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)
Detergent Compositions (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK95305100T 1994-07-21 1995-07-21 Rekombinant termostabilt enzym, som frigør trehalose fra ikke-reducerende saccharid DK0697461T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP19018094		1994-07-21
JP10912895		1995-04-11
JP18976095A JP3557289B2 (ja)	1994-07-21	1995-07-04	非還元性糖質からトレハロースを遊離する組換え型耐熱性酵素

Publications (1)

Publication Number	Publication Date
DK0697461T3 true DK0697461T3 (da)	1999-06-21

Family

ID=27311404

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95305100T DK0697461T3 (da)	1994-07-21	1995-07-21	Rekombinant termostabilt enzym, som frigør trehalose fra ikke-reducerende saccharid

Country Status (12)

Country	Link
US (3)	US5856146A (da)
EP (1)	EP0697461B1 (da)
JP (1)	JP3557289B2 (da)
KR (1)	KR100387303B1 (da)
AT (1)	ATE171726T1 (da)
AU (1)	AU690285B2 (da)
CA (1)	CA2154333C (da)
DE (1)	DE69505075T2 (da)
DK (1)	DK0697461T3 (da)
ES (1)	ES2123212T3 (da)
IL (1)	IL114643A0 (da)
TW (1)	TW418255B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1130101B1 (en) *	1994-06-15	2008-10-15	Kirin Beer Kabushiki Kaisha	Transferase and amylase, process for producing the enzymes, use thereof, and genes coding for the same
JPH11116588A (ja)	1997-10-16	1999-04-27	Hayashibara Biochem Lab Inc	トレハロース及び糖アルコールの製造方法
JP4203159B2 (ja)	1997-12-09	2008-12-24	株式会社林原生物化学研究所	神経機能調節剤
JP4295840B2 (ja) *	1997-12-09	2009-07-15	株式会社林原生物化学研究所	血行改善剤
JP3958884B2 (ja)	1998-09-11	2007-08-15	株式会社林原生物化学研究所	非還元性糖質生成酵素及びトレハロース遊離酵素ならびに該酵素を用いる糖質の製造方法
JP2000262252A (ja)	1999-01-11	2000-09-26	Aoba Kasei Kk	タンパク質変性抑制剤、冷凍変性が抑制された擂潰食肉およびその製造方法ならびに練り製品の製造方法
JP4652540B2 (ja)	2000-03-02	2011-03-16	株式会社林原生物化学研究所	体臭抑制剤とその用途
AU781975B2 (en)	2000-09-14	2005-06-23	Hayashibara Co., Ltd	Pharmaceutical composition for ophthalmic use
JP4982643B2 (ja) *	2000-09-14	2012-07-25	株式会社林原	眼科用医薬組成物
JP4754066B2 (ja)	2000-12-22	2011-08-24	株式会社林原生物化学研究所	抗関節障害剤
US6803230B2 (en) *	2001-04-27	2004-10-12	Alexion Pharmaceuticals, Inc.	Phagemid vectors
DE10315640A1 (de) *	2003-04-04	2004-10-14	Ignatov, Konstantin	Verfahren zur kontrollierten Freisetzung von Komponenten in eine Lösung
KR100967716B1 (ko) *	2004-05-13	2010-07-07	주식회사 포스코	신규 열안정성 글루코네이트 탈수효소 및 이의 용도
CN1953755A (zh) *	2004-05-17	2007-04-25	株式会社林原生物化学研究所	强化接触水系环境的生物的生命活动和/或扩张生命活动适合区域的方法
GB2416352B (en) *	2004-07-21	2009-01-28	Bioline Ltd	A method for performing the hot start of enzymatic reactions
US20070232421A1 (en) *	2006-03-06	2007-10-04	Nye S C	Basketball system
US7691014B2 (en) *	2005-01-12	2010-04-06	Lifetime Products, Inc.	Basketball system
US20070213147A1 (en) *	2006-03-03	2007-09-13	Nye S C	Basketball system
US20070238559A1 (en) *	2005-01-12	2007-10-11	Nye S C	Basketball system
JP5184768B2 (ja) *	2006-09-05	2013-04-17	株式会社林原	トレハロース高含有糖液の回収方法並びに結晶トレハロースの製造方法
JP5993674B2 (ja) *	2012-09-12	2016-09-14	株式会社林原	α，α−トレハロース二含水結晶含有粉末の製造方法
CN110628741B (zh) *	2017-09-13	2021-01-29	江南大学	麦芽寡糖基海藻糖合成酶突变体及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS50154485A (da)	1974-05-31	1975-12-12
JPS5823799A (ja) *	1981-08-03	1983-02-12	株式会社林原生物化学研究所	高純度マルト−スの製造方法
JPS5872598A (ja) *	1981-10-26	1983-04-30	Hayashibara Biochem Lab Inc	高純度イソマルト−スの製造方法
JPS58216695A (ja)	1982-06-07	1983-12-16	Otsuka Shokuhin Kogyo Kk	トレハロ−スの製造方法
ATE182359T1 (de) *	1992-12-28	1999-08-15	Hayashibara Biochem Lab	Nichtreduzierendes saccharidbildendes enzym, und dessen herstellung und verwendungen
JP3559585B2 (ja) *	1993-06-03	2004-09-02	株式会社林原生物化学研究所	トレハロース遊離酵素とその製造方法並びに用途
JP3557277B2 (ja) *	1994-06-25	2004-08-25	株式会社林原生物化学研究所	耐熱性トレハロース遊離酵素とその製造方法並びに用途

1995
- 1995-07-04 JP JP18976095A patent/JP3557289B2/ja not_active Expired - Fee Related
- 1995-07-18 IL IL11464395A patent/IL114643A0/xx unknown
- 1995-07-20 CA CA002154333A patent/CA2154333C/en not_active Expired - Lifetime
- 1995-07-21 EP EP95305100A patent/EP0697461B1/en not_active Expired - Lifetime
- 1995-07-21 ES ES95305100T patent/ES2123212T3/es not_active Expired - Lifetime
- 1995-07-21 KR KR1019950021518A patent/KR100387303B1/ko not_active Expired - Lifetime
- 1995-07-21 AT AT95305100T patent/ATE171726T1/de not_active IP Right Cessation
- 1995-07-21 DK DK95305100T patent/DK0697461T3/da active
- 1995-07-21 US US08/505,377 patent/US5856146A/en not_active Expired - Lifetime
- 1995-07-21 AU AU27131/95A patent/AU690285B2/en not_active Expired
- 1995-07-21 DE DE69505075T patent/DE69505075T2/de not_active Expired - Fee Related
- 1995-07-25 TW TW084107697A patent/TW418255B/zh not_active IP Right Cessation
1997
- 1997-02-11 US US08/798,269 patent/US6027918A/en not_active Expired - Fee Related
1998
- 1998-04-06 US US09/055,210 patent/US6346394B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0697461B1 (en)	1998-09-30
TW418255B (en)	2001-01-11
DE69505075T2 (de)	1999-06-02
ATE171726T1 (de)	1998-10-15
JPH08336388A (ja)	1996-12-24
US5856146A (en)	1999-01-05
CA2154333A1 (en)	1996-01-22
KR100387303B1 (ko)	2003-08-21
DE69505075D1 (de)	1998-11-05
AU2713195A (en)	1996-02-01
JP3557289B2 (ja)	2004-08-25
US6346394B1 (en)	2002-02-12
EP0697461A1 (en)	1996-02-21
ES2123212T3 (es)	1999-01-01
CA2154333C (en)	2009-10-06
IL114643A0 (en)	1995-12-31
AU690285B2 (en)	1998-04-23
US6027918A (en)	2000-02-22

Publication	Publication Date	Title
IL114643A0 (en)	1995-12-31	Recombinant thermostable enzyme which releases trehalose from non-reducing saccharide and its preparation
DK0709461T3 (da)	1999-06-21	DNA, som koder for et rekombinant termostabilt enzym, som danner ikke-reducerende saccharid ud fra reducerende stivelsesrel
WO1996039528A3 (en)	1997-02-13	MUTANT α-AMYLASE
ATE490312T1 (de)	2010-12-15	Maltogene alpha-amylase varianten
ES2150905T3 (es)	2000-12-16	Hidrolisis enzimatica del almidon a la glucosa con la ayuda de una enzima producida por ingenieria genetica.
BR9611617A (pt)	1999-04-06	Método e composições enzimáticas para o tratamento de sangue hemorrágico intravitreal
DE69939829D1 (de)	2008-12-11	Stärke "debranching-enzyme"
CA2252607A1 (en)	1997-10-30	Medical devices with improved elastic response
TW354756B (en)	1999-03-21	A process for the non-random cleavage of starch
IL121713A0 (en)	1998-02-22	Method for decreasing glucose polymerization
EP1130101A3 (en)	2004-12-01	Transferase and amylase, process for producing the enzymes, use thereof, and genes coding for the same
GR3004119T3 (da)	1993-03-31
CA2038579A1 (en)	1991-09-22	Utilization of enzymes
EP0301522A3 (en)	1989-11-08	Process for producton of isomaltulose
DE69529953D1 (de)	2003-04-24	Hitzebeständige rekombinante Enzyme für die Umsetzung von Maltose in Trehalose
EP0373107A3 (en)	1991-11-21	Use of enzymes of Aureobasidium pullulans in pulp bleaching
EP1445325A4 (en)	2006-12-20	PROCESS FOR THE PREPARATION OF ISOMALTOSE AND ISOMALTITE AND USE THEREOF
AU2575200A (en)	2000-09-14	Alpha-agarase and process for producing the same
ES2022934B3 (es)	1991-12-16	Enzimas modificadas con poliuretano.
CA2193405A1 (en)	1997-06-20	Eyewash intended in particular for the treatment of the dry eye syndrome
Yoo et al.	2000	Purification and Characterization of a Thermostable ${\beta}-Glycosidase $ from Thermus caldophilus GK24
EP0350737A3 (en)	1990-08-01	Thermostable amylase and use thereof
EP0365029A3 (en)	1991-10-16	Method of systhesizing optically active beta-halolactic acid or glycidic acid
TH20328A (th)	1996-09-03	รีคอมบิแนนท์เอนไซม์ทนความร้อนที่ปลดปล่อย ทรีฮาโลสจากนอนรีดิวซิงแซคคาไรด์ชนิดแป้ง
MX9702923A (es)	1997-07-31	Un metodo para incrementar los niveles de monosacaridos en la sacarificacion del almidon y enzimas para el mismo.