DK0699676T3 - Fysisk form af et dihydro-2,3-benzodiazepinderivat - Google Patents
Fysisk form af et dihydro-2,3-benzodiazepinderivatInfo
- Publication number
- DK0699676T3 DK0699676T3 DK95306048T DK95306048T DK0699676T3 DK 0699676 T3 DK0699676 T3 DK 0699676T3 DK 95306048 T DK95306048 T DK 95306048T DK 95306048 T DK95306048 T DK 95306048T DK 0699676 T3 DK0699676 T3 DK 0699676T3
- Authority
- DK
- Denmark
- Prior art keywords
- dihydro
- physical form
- benzodiazepine derivative
- acetyl
- methyl
- Prior art date
Links
- MGRVRXRGTBOSHW-UHFFFAOYSA-N (aminomethyl)phosphonic acid Chemical compound NCP(O)(O)=O MGRVRXRGTBOSHW-UHFFFAOYSA-N 0.000 abstract 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000636 p-nitrophenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)[N+]([O-])=O 0.000 abstract 1
- 238000000634 powder X-ray diffraction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29864594A | 1994-08-31 | 1994-08-31 | |
| US08/413,024 US6288057B1 (en) | 1994-08-31 | 1995-03-28 | Physical form of dihydro-2,3-benzodiazepine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0699676T3 true DK0699676T3 (da) | 2001-02-26 |
Family
ID=26970797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95306048T DK0699676T3 (da) | 1994-08-31 | 1995-08-30 | Fysisk form af et dihydro-2,3-benzodiazepinderivat |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0699676B1 (da) |
| JP (1) | JP3449834B2 (da) |
| CN (1) | CN1073995C (da) |
| AT (1) | ATE199086T1 (da) |
| AU (1) | AU696243B2 (da) |
| BR (1) | BR9503844A (da) |
| CA (1) | CA2157247C (da) |
| CZ (1) | CZ288267B6 (da) |
| DE (1) | DE69520059T2 (da) |
| DK (1) | DK0699676T3 (da) |
| ES (1) | ES2153879T3 (da) |
| FI (1) | FI112490B (da) |
| GR (1) | GR3035801T3 (da) |
| HU (1) | HUT72673A (da) |
| IL (1) | IL115101A (da) |
| NO (1) | NO310462B1 (da) |
| NZ (1) | NZ272897A (da) |
| PT (1) | PT699676E (da) |
| TR (1) | TR199501072A2 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2338492A1 (en) | 2009-12-24 | 2011-06-29 | Universidad del Pais Vasco | Methods and compositions for the treatment of alzheimer |
| NO2780523T3 (da) * | 2014-06-25 | 2018-03-24 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU219778B (hu) * | 1990-12-21 | 2001-07-30 | Gyógyszerkutató Intézet Közös Vállalat | Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények |
| HU219777B (hu) * | 1993-07-02 | 2001-07-30 | Gyógyszerkutató Intézet Kft. | Optikailag aktív 1-(4-nitro-fenil)-4-metil-7,8-metiléndioxi-3,4-dihidro-5H-2,3-benzodiazepin és eljárás előállítására |
-
1995
- 1995-08-29 TR TR95/01072A patent/TR199501072A2/xx unknown
- 1995-08-30 DK DK95306048T patent/DK0699676T3/da active
- 1995-08-30 CA CA002157247A patent/CA2157247C/en not_active Expired - Fee Related
- 1995-08-30 CZ CZ19952220A patent/CZ288267B6/cs not_active IP Right Cessation
- 1995-08-30 HU HU9502547A patent/HUT72673A/hu unknown
- 1995-08-30 NZ NZ272897A patent/NZ272897A/en not_active IP Right Cessation
- 1995-08-30 CN CN95109526A patent/CN1073995C/zh not_active Expired - Fee Related
- 1995-08-30 JP JP22157295A patent/JP3449834B2/ja not_active Expired - Fee Related
- 1995-08-30 BR BR9503844A patent/BR9503844A/pt not_active IP Right Cessation
- 1995-08-30 EP EP95306048A patent/EP0699676B1/en not_active Expired - Lifetime
- 1995-08-30 NO NO19953395A patent/NO310462B1/no not_active IP Right Cessation
- 1995-08-30 AU AU30356/95A patent/AU696243B2/en not_active Ceased
- 1995-08-30 DE DE69520059T patent/DE69520059T2/de not_active Expired - Lifetime
- 1995-08-30 FI FI954065A patent/FI112490B/fi active
- 1995-08-30 ES ES95306048T patent/ES2153879T3/es not_active Expired - Lifetime
- 1995-08-30 PT PT95306048T patent/PT699676E/pt unknown
- 1995-08-30 IL IL11510195A patent/IL115101A/en not_active IP Right Cessation
- 1995-08-30 AT AT95306048T patent/ATE199086T1/de not_active IP Right Cessation
-
2001
- 2001-04-27 GR GR20010400649T patent/GR3035801T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI954065L (fi) | 1996-03-01 |
| AU696243B2 (en) | 1998-09-03 |
| PT699676E (pt) | 2001-05-31 |
| GR3035801T3 (en) | 2001-07-31 |
| ES2153879T3 (es) | 2001-03-16 |
| HU9502547D0 (en) | 1995-10-30 |
| EP0699676B1 (en) | 2001-02-07 |
| DE69520059D1 (de) | 2001-03-15 |
| DE69520059T2 (de) | 2001-06-21 |
| EP0699676A1 (en) | 1996-03-06 |
| IL115101A (en) | 1998-12-27 |
| NO310462B1 (no) | 2001-07-09 |
| FI954065A0 (fi) | 1995-08-30 |
| JPH0892255A (ja) | 1996-04-09 |
| HUT72673A (en) | 1996-05-28 |
| CZ288267B6 (en) | 2001-05-16 |
| NZ272897A (en) | 1997-03-24 |
| NO953395L (no) | 1996-03-01 |
| CA2157247C (en) | 2000-10-24 |
| CN1073995C (zh) | 2001-10-31 |
| CN1122338A (zh) | 1996-05-15 |
| FI112490B (fi) | 2003-12-15 |
| NO953395D0 (no) | 1995-08-30 |
| ATE199086T1 (de) | 2001-02-15 |
| IL115101A0 (en) | 1995-12-08 |
| AU3035695A (en) | 1996-03-14 |
| TR199501072A2 (tr) | 1996-06-21 |
| HK1013819A1 (en) | 1999-09-10 |
| JP3449834B2 (ja) | 2003-09-22 |
| CZ222095A3 (en) | 1996-03-13 |
| BR9503844A (pt) | 1996-09-10 |
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