DK0700395T3 - Indolderivater som steroid 5-alfa-reduktase-inhibitorer - Google Patents

Indolderivater som steroid 5-alfa-reduktase-inhibitorer

Info

Publication number: DK0700395T3
Authority: DK; Denmark
Prior art keywords: pct; steroid; reductase inhibitors; indole derivatives; alpha reductase
Prior art date: 1993-05-28

Application number

DK94917676.2T

Other languages

Danish (da)

English (en)

Inventor

Julian Blagg

Graham Nigel Maw

David James Rawson

Original Assignee

Pfizer Ltd

Pfizer Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-05-28

Filing date

1994-05-26

Publication date

1997-10-13

1993-05-28 Priority claimed from GB939311008A external-priority patent/GB9311008D0/en

1994-05-26 Application filed by Pfizer Ltd, Pfizer Res & Dev filed Critical Pfizer Ltd

1997-10-13 Application granted granted Critical

1997-10-13 Publication of DK0700395T3 publication Critical patent/DK0700395T3/da

Links

239000002677 5-alpha reductase inhibitor Substances 0.000 title 1
229940054051 antipsychotic indole derivative Drugs 0.000 title 1
150000002475 indoles Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
108010029908 3-oxo-5-alpha-steroid 4-dehydrogenase Proteins 0.000 abstract 1
102000001779 3-oxo-5-alpha-steroid 4-dehydrogenase Human genes 0.000 abstract 1
206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 1
208000004403 Prostatic Hyperplasia Diseases 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000004299 tetrazol-5-yl group Chemical group [H]N1N=NC(*)=N1 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK94917676.2T 1993-05-28 1994-05-26 Indolderivater som steroid 5-alfa-reduktase-inhibitorer DK0700395T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB939311008A GB9311008D0 (en)	1993-05-28	1993-05-28	Indoles
GB939317529A GB9317529D0 (en)	1993-05-28	1993-08-20	Indoles

Publications (1)

Publication Number	Publication Date
DK0700395T3 true DK0700395T3 (da)	1997-10-13

Family

ID=26302960

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94917676.2T DK0700395T3 (da)	1993-05-28	1994-05-26	Indolderivater som steroid 5-alfa-reduktase-inhibitorer

Country Status (14)

Country	Link
US (2)	US5696146A (de)
EP (1)	EP0700395B1 (de)
JP (1)	JP2757969B2 (de)
AT (1)	ATE154352T1 (de)
AU (1)	AU6930494A (de)
CA (1)	CA2163778C (de)
DE (1)	DE69403793T2 (de)
DK (1)	DK0700395T3 (de)
ES (1)	ES2102863T3 (de)
FI (1)	FI113864B (de)
GR (1)	GR3024366T3 (de)
HU (1)	HU9501935D0 (de)
IL (1)	IL109728A0 (de)
WO (1)	WO1994027990A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9204365D0 (en) *	1992-02-28	1992-04-08	Pfizer Ltd	Indoles
GB9317096D0 (en) *	1993-08-17	1993-09-29	Pfizer Ltd	Indoles
AU2007303219A1 (en)	2006-10-02	2008-04-10	Cortendo Ab (Publ)	Ketoconazole enantiomer in humans

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9011335D0 (en) *	1990-05-21	1990-07-11	Fujisawa Pharmaceutical Co	Indolebutyric acid derivatives and process for preparation thereof
GB9204365D0 (en) *	1992-02-28	1992-04-08	Pfizer Ltd	Indoles
GB9317096D0 (en) *	1993-08-17	1993-09-29	Pfizer Ltd	Indoles

1994
- 1994-05-23 IL IL10972894A patent/IL109728A0/xx unknown
- 1994-05-26 ES ES94917676T patent/ES2102863T3/es not_active Expired - Lifetime
- 1994-05-26 US US08/553,589 patent/US5696146A/en not_active Expired - Fee Related
- 1994-05-26 EP EP94917676A patent/EP0700395B1/de not_active Expired - Lifetime
- 1994-05-26 DE DE69403793T patent/DE69403793T2/de not_active Expired - Fee Related
- 1994-05-26 AT AT94917676T patent/ATE154352T1/de not_active IP Right Cessation
- 1994-05-26 JP JP7500251A patent/JP2757969B2/ja not_active Expired - Lifetime
- 1994-05-26 HU HU9501935A patent/HU9501935D0/hu unknown
- 1994-05-26 WO PCT/EP1994/001760 patent/WO1994027990A1/en not_active Ceased
- 1994-05-26 AU AU69304/94A patent/AU6930494A/en not_active Abandoned
- 1994-05-26 DK DK94917676.2T patent/DK0700395T3/da active
- 1994-05-26 CA CA002163778A patent/CA2163778C/en not_active Expired - Fee Related
1995
- 1995-11-27 FI FI955707A patent/FI113864B/fi not_active IP Right Cessation
1997
- 1997-08-06 GR GR970402013T patent/GR3024366T3/el unknown
- 1997-12-02 US US08/982,735 patent/US5922747A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2163778C (en)	1999-04-27
DE69403793T2 (de)	1997-09-25
US5922747A (en)	1999-07-13
EP0700395B1 (de)	1997-06-11
FI955707A0 (fi)	1995-11-27
GR3024366T3 (en)	1997-11-28
DE69403793D1 (de)	1997-07-17
EP0700395A1 (de)	1996-03-13
WO1994027990A1 (en)	1994-12-08
ES2102863T3 (es)	1997-08-01
CA2163778A1 (en)	1994-12-08
IL109728A0 (en)	1994-08-26
JP2757969B2 (ja)	1998-05-25
AU6930494A (en)	1994-12-20
JPH08506350A (ja)	1996-07-09
ATE154352T1 (de)	1997-06-15
FI113864B (fi)	2004-06-30
FI955707L (fi)	1995-11-27
US5696146A (en)	1997-12-09
HU9501935D0 (en)	1995-09-28

Publication	Publication Date	Title
FI960399A0 (fi)	1996-01-29	Perhydroisoindolijohdannaisia P-aineen antagonisteina
DK0677046T3 (da)	1997-09-01	Piperazinderivater som 5-HT-antagonister.
DE60226469D1 (de)	2008-06-19	Biphenylkarbonsäureamidderivate als p38 kinase-inhibitoren
DK0730594T3 (da)	2000-03-27	9-hydroxy-pyrido{1,2-a}pyrimidin-4-on-ether-derivater
DE69719358D1 (de)	2003-04-03	Substituierte dihydrobenzofurane als pde-hemmstoffe
NO304227B1 (no)	1998-11-16	Substituerte imidazolderivater, preparat som inneholder disse og deres anvendelse
NO943187D0 (no)	1994-08-29	Indolderivater som steroid 5-alfa-reduktasehemmere
MX9400253A (es)	1994-08-31	Derivados de piperazina, proceso para su preparacion y composiciones farmaceuticas que los contienen.
DK0700395T3 (da)	1997-10-13	Indolderivater som steroid 5-alfa-reduktase-inhibitorer
MX9303605A (es)	1993-12-01	Derivados de azabicicloheptano n-substituidas, su obtencion y uso.
DE69413831D1 (de)	1998-11-12	Phenoxyphenylcyclopentenyl-hydroxyharnstoffe
ATE163402T1 (de)	1998-03-15	Substituierte ortho- ethenylphenylessigsäurederivate
DE69405760D1 (de)	1997-10-23	4-aza-pregnan-5-alpha-reductase isozym 1 inhibitoren
DK0687257T3 (da)	1997-08-18	4-amino-2-(hetero)aryl-butanamider anvendelige som 5HT1A-antagonister
YU31502A (sh)	2004-12-31	Kristali kao inhibitori natrijum-vodonik izmenjivača tip1
ES2164665T3 (es)	2002-03-01	Inhibidores de proteasas retrovirales.