DK0708657T3 - Sammensætninger til nasal administration af desmopression - Google Patents

Sammensætninger til nasal administration af desmopression

Info

Publication number: DK0708657T3
Authority: DK; Denmark
Prior art keywords: composition; nasal administration; container; assembly; desmopression
Prior art date: 1993-06-29

Application number

DK94920618T

Other languages

Danish (da)

English (en)

Inventor

Alan Harris

Original Assignee

Ferring Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-29

Filing date

1994-06-22

Publication date

2001-10-15

1994-06-22 Application filed by Ferring Bv filed Critical Ferring Bv

2001-10-15 Application granted granted Critical

2001-10-15 Publication of DK0708657T3 publication Critical patent/DK0708657T3/da

Links

239000000203 mixture Substances 0.000 title abstract 5
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
239000000872 buffer Substances 0.000 abstract 2
OSASVXMJTNOKOY-UHFFFAOYSA-N chlorobutanol Chemical compound CC(C)(O)C(Cl)(Cl)Cl OSASVXMJTNOKOY-UHFFFAOYSA-N 0.000 abstract 2
239000007921 spray Substances 0.000 abstract 2
KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
108010000437 Deamino Arginine Vasopressin Proteins 0.000 abstract 1
229910019142 PO4 Inorganic materials 0.000 abstract 1
GXBMIBRIOWHPDT-UHFFFAOYSA-N Vasopressin Natural products N1C(=O)C(CC=2C=C(O)C=CC=2)NC(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CCCN=C(N)N)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C1CC1=CC=CC=C1 GXBMIBRIOWHPDT-UHFFFAOYSA-N 0.000 abstract 1
108010004977 Vasopressins Proteins 0.000 abstract 1
102000002852 Vasopressins Human genes 0.000 abstract 1
KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 abstract 1
229960000686 benzalkonium chloride Drugs 0.000 abstract 1
CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
229960004926 chlorobutanol Drugs 0.000 abstract 1
229960004281 desmopressin Drugs 0.000 abstract 1
NFLWUMRGJYTJIN-NXBWRCJVSA-N desmopressin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSCCC(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O)=O)CCC(=O)N)C1=CC=CC=C1 NFLWUMRGJYTJIN-NXBWRCJVSA-N 0.000 abstract 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
239000010452 phosphate Substances 0.000 abstract 1
239000003755 preservative agent Substances 0.000 abstract 1
230000002335 preservative effect Effects 0.000 abstract 1
239000011780 sodium chloride Substances 0.000 abstract 1
230000000087 stabilizing effect Effects 0.000 abstract 1
230000002485 urinary effect Effects 0.000 abstract 1
229960003726 vasopressin Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Immunology (AREA)
Diabetes (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Otolaryngology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Furan Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK94920618T 1993-06-29 1994-06-22 Sammensætninger til nasal administration af desmopression DK0708657T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8489493A	1993-06-29	1993-06-29
PCT/SE1994/000623 WO1995001183A1 (en)	1993-06-29	1994-06-22	Compositions for nasal administration of desmopressin

Publications (1)

Publication Number	Publication Date
DK0708657T3 true DK0708657T3 (da)	2001-10-15

Family

ID=22187889

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94920618T DK0708657T3 (da)	1993-06-29	1994-06-22	Sammensætninger til nasal administration af desmopression

Country Status (19)

Country	Link
US (1)	US5498598A (de)
EP (1)	EP0708657B1 (de)
JP (1)	JPH09502425A (de)
KR (1)	KR100193104B1 (de)
CN (1)	CN1101701C (de)
AT (1)	ATE203412T1 (de)
CA (1)	CA2166312C (de)
CZ (1)	CZ282456B6 (de)
DE (1)	DE69427820T2 (de)
DK (1)	DK0708657T3 (de)
ES (1)	ES2158898T3 (de)
GR (1)	GR3036936T3 (de)
HU (1)	HU221617B1 (de)
NZ (1)	NZ268442A (de)
PL (1)	PL176317B1 (de)
PT (1)	PT708657E (de)
RU (1)	RU2135204C1 (de)
SK (1)	SK282844B6 (de)
WO (1)	WO1995001183A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5482931A (en) *	1993-06-29	1996-01-09	Ferring Ab	Stabilized pharmaceutical peptide compositions
EP0710243B1 (de) *	1993-06-29	2000-06-14	Ferring B.V.	Synthese zyklischer peptide
US5674850A (en) *	1993-12-23	1997-10-07	Ferring Ab	High purity desmopressin produced in large single batches
SE9400918L (sv) *	1994-03-18	1995-09-19	Anne Fjellstad Paulsen	Stabiliserad komposition för oral administrering av peptider
US5763398A (en) *	1996-06-20	1998-06-09	Ferring B.V.	Nasal administration of desmopressin
US5916582A (en) *	1996-07-03	1999-06-29	Alza Corporation	Aqueous formulations of peptides
GB9614235D0 (en) *	1996-07-06	1996-09-04	Danbiosyst Uk	Composition for enhanced uptake of polar drugs from mucosal surfaces
US5922680A (en) *	1996-10-23	1999-07-13	Ferring, B.V.	Stabilized composition for oral administration of peptides
US8765177B2 (en) *	1997-09-12	2014-07-01	Columbia Laboratories, Inc.	Bioadhesive progressive hydration tablets
US7153845B2 (en)	1998-08-25	2006-12-26	Columbia Laboratories, Inc.	Bioadhesive progressive hydration tablets
JP2001233787A (ja)	2000-02-04	2001-08-28	Patents Exploitation Co Bv	小・中サイズのペプチド含有薬学的組成物
US6641799B2 (en)	2002-04-03	2003-11-04	Nos Spray, Inc.	Nasal spray for decongesting nasal passages
GB0210397D0 (en) *	2002-05-07	2002-06-12	Ferring Bv	Pharmaceutical formulations
WO2003097080A1 (en) *	2002-05-15	2003-11-27	Sun Pharmaceutical Industries Limited	A stable aqueous composition of a peptide
PT1530967E (pt) *	2003-11-13	2006-09-29	Ferring Bv	Embalagem blister e uma forma de dosagem solida que compreende desmopressina.
SE0600482L (sv) *	2006-03-02	2006-11-14	Ferring Int Ct Sa	Farmaceutisk sammansättning innefattande desmopressin, kiseldioxid och stärkelse
WO2009021007A1 (en)	2007-08-06	2009-02-12	Serenity Pharmaceuticals Corporation	Methods and devices for desmopressin drug delivery
CN101372504B (zh) *	2007-08-22	2011-05-18	深圳翰宇药业股份有限公司	一种纯化去氨加压素的方法
US20100286045A1 (en)	2008-05-21	2010-11-11	Bjarke Mirner Klein	Methods comprising desmopressin
US11963995B2 (en)	2008-05-21	2024-04-23	Ferring B.V.	Methods comprising desmopressin
NO3085381T3 (de)	2008-05-21	2018-09-15
AU2015261630B2 (en) *	2008-12-22	2017-09-14	Acerus Pharmaceuticals USA, LLC	Intranasal desmopressin administration
US20100160214A1 (en) *	2008-12-22	2010-06-24	Serenity Pharmaceuticals Corporation	Desmopressin composition
SG10201509152VA (en) *	2008-12-22	2015-12-30	Allergan Inc	Intranasal desmopressin administration
CA2765221C (en) *	2009-06-18	2017-10-03	Allergan, Inc.	Safe desmopressin administration
CN102440957B (zh) *	2011-12-16	2013-09-25	深圳市健元医药科技有限公司	醋酸特利加压素鼻腔喷雾剂及其制备方法
AU2015370666B2 (en)	2014-12-22	2020-09-03	Arovella Therapeutics Limited	Prevention and treatment of metastatic disease in thrombocytotic cancer patients
WO2024105521A1 (en) *	2022-11-17	2024-05-23	Shilpa Medicare Limited	Stable peptide pharmaceutical composition

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4271068A (en) *	1968-05-10	1981-06-02	Ciba-Geigy Corporation	Process for the manufacture of cystine-containing peptides
CH517705A (de) *	1969-12-16	1972-01-15	Ciba Geigy Ag	Verfahren zur Herstellung von Cystin-haltigen Peptiden
US3929758A (en) *	1974-09-12	1975-12-30	Armour Pharma	Cyclization of cysteine-containing peptides
US4033940A (en) *	1975-11-12	1977-07-05	Armour Pharmaceutical Company	Cyclization of peptides
US4093610A (en) *	1977-01-31	1978-06-06	American Home Products Corporation	Process for producing triglycyl-lysine vasopressin and intermediates therefor
US4216141A (en) *	1978-07-19	1980-08-05	The Salk Institute For Biological Studies	Method for cyclization of peptides
DE2923787A1 (de) *	1979-06-12	1980-12-18	Max Planck Gesellschaft	Verfahren zur selektiven bildung von disulfidbruecken in polypeptiden und die dabei erhaltenen produkte als wirkstoffe enthaltende arzneimittel
IE56021B1 (en) *	1982-10-13	1991-03-27	Akzo Nv	Peptides
DK489683A (da) *	1982-10-27	1984-04-28	Amano Pharma Co Ltd	Fremgangsmaade til fremstilling af peptider
JPS61194034A (ja) *	1985-02-25	1986-08-28	Teijin Ltd	経鼻投与用粉末状組成物
WO1988005661A1 (en) *	1987-01-30	1988-08-11	Biomed Research Consultants, Limited	Vasopressin-based pharmaceutical compositions
US5066716A (en) *	1988-12-13	1991-11-19	The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	Synthesis of chloroacetyl and bromoacetyl modified peptides for the preparation of synthetic peptide polymers, conjugated peptides, and cyclic peptides
ATE108326T1 (de) *	1989-01-30	1994-07-15	Corint Ltd	Wässerige desmopressin-cmc enthaltende arzneizubereitung.
DE69001991T2 (de) *	1989-11-16	1993-09-23	Phidea Spa	Fluessige arzneimittel zur nasalen anwendung, die ein polypeptid als wirksubstanz enthalten.

1994
- 1994-06-22 DK DK94920618T patent/DK0708657T3/da active
- 1994-06-22 DE DE69427820T patent/DE69427820T2/de not_active Expired - Lifetime
- 1994-06-22 AT AT94920618T patent/ATE203412T1/de not_active IP Right Cessation
- 1994-06-22 NZ NZ268442A patent/NZ268442A/en not_active IP Right Cessation
- 1994-06-22 CN CN94192594A patent/CN1101701C/zh not_active Expired - Fee Related
- 1994-06-22 RU RU96101997A patent/RU2135204C1/ru not_active IP Right Cessation
- 1994-06-22 EP EP94920618A patent/EP0708657B1/de not_active Expired - Lifetime
- 1994-06-22 CA CA002166312A patent/CA2166312C/en not_active Expired - Fee Related
- 1994-06-22 KR KR1019950706028A patent/KR100193104B1/ko not_active Expired - Fee Related
- 1994-06-22 PL PL94312204A patent/PL176317B1/pl unknown
- 1994-06-22 ES ES94920618T patent/ES2158898T3/es not_active Expired - Lifetime
- 1994-06-22 HU HU9503833A patent/HU221617B1/hu not_active IP Right Cessation
- 1994-06-22 JP JP7503426A patent/JPH09502425A/ja active Pending
- 1994-06-22 PT PT94920618T patent/PT708657E/pt unknown
- 1994-06-22 SK SK1650-95A patent/SK282844B6/sk not_active IP Right Cessation
- 1994-06-22 CZ CZ953390A patent/CZ282456B6/cs not_active IP Right Cessation
- 1994-06-22 WO PCT/SE1994/000623 patent/WO1995001183A1/en not_active Ceased
1995
- 1995-04-25 US US08/430,131 patent/US5498598A/en not_active Expired - Lifetime
2001
- 2001-10-18 GR GR20010401804T patent/GR3036936T3/el unknown

Also Published As

Publication number	Publication date
CN1101701C (zh)	2003-02-19
EP0708657A1 (de)	1996-05-01
CZ282456B6 (cs)	1997-07-16
CZ339095A3 (en)	1996-09-11
WO1995001183A1 (en)	1995-01-12
RU2135204C1 (ru)	1999-08-27
US5498598A (en)	1996-03-12
GR3036936T3 (en)	2002-01-31
ATE203412T1 (de)	2001-08-15
EP0708657B1 (de)	2001-07-25
DE69427820T2 (de)	2001-11-08
PL176317B1 (pl)	1999-05-31
DE69427820D1 (de)	2001-08-30
KR100193104B1 (ko)	1999-06-15
HU9503833D0 (en)	1996-02-28
PL312204A1 (en)	1996-04-01
CA2166312A1 (en)	1995-01-12
SK165095A3 (en)	1996-11-06
KR960703339A (ko)	1996-08-17
SK282844B6 (sk)	2002-12-03
HUT73776A (en)	1996-09-30
JPH09502425A (ja)	1997-03-11
ES2158898T3 (es)	2001-09-16
CN1126439A (zh)	1996-07-10
HK1000906A1 (en)	2002-03-08
HU221617B1 (hu)	2002-12-28
PT708657E (pt)	2001-11-30
CA2166312C (en)	2002-04-23
NZ268442A (en)	1996-09-25

Publication	Publication Date	Title
DE69427820D1 (de)	2001-08-30	Zusammensetzungen zur nasalen verabreichung von desmopressin
PL316689A1 (en)	1997-02-03	Anti-dandruff shampoo
KR960703340A (ko)	1996-08-17	안정화된 약학적 펩티드 조성물
IT1255258B (it)	1995-10-20	Composizioni farmaceutiche per l'applicazione per via nasale.
AR018526A1 (es)	2001-11-28	COMPOSICION FARMACEUTICA NO LIOFILIZADA EN FORMA DE SOLUCIoN QUE COMPRENDE LA HORMONA PARATIROIDEA HUMANA, PROCESO PARA PREPARA UN FRASCO O CARTUCHO QUE LA CONTIENE, PROCESO PARA PREPARAR DICHA COMPOSICIoN, FRASCO O CARTUCHO QUE CONTIENE LA COMPOSICIoN Y USO DE LA MISMA PARA LA FABRICACIoN DE UN MED
JO2034B1 (en)	1999-05-15	Isotopes of the hormone peptide its uses and the chemical compounds it contains
EP0185374A3 (en)	1987-09-30	Liquid diclofenac preparations
AU3183389A (en)	1989-09-22	Human relaxin formulation
HK27389A (en)	1989-04-07	Galenic compositions comprising calcitonin and their use
PL297902A1 (en)	1993-09-06	Novel cyclosporines and method of obtaining them
IL136591A0 (en)	2001-06-14	Nasal solutions
AU6414498A (en)	1998-10-20	Composition comprising immunoglobulin
MX9701170A (es)	1997-05-31	Composicion antitranspirante en aerosol con poco propulsor.
MX9703024A (es)	1997-10-31	Cristalizacion de levobupivacaina y sus analogos.
HU9501801D0 (en)	1995-08-28	Lactame-compounds as pharmaceutical active component
BG103632A (en)	2000-03-31	Pharmaceutical compositions containing ibuprophene and domperidon for migraine treatment
BG103306A (en)	2000-01-31	Liquid allendronate compositions
NZ337798A (en)	2001-03-30	Pharmaceutical compositions containing lamivudine
YU40398A (sh)	2001-07-10	Kompozicija nazalnog spreja za davanje sredstva za lečenje odloženog napada emezisa
AU6520196A (en)	1997-03-05	Aqueous compositions containing ciprofloxacine, and related use and process
EP0212837A3 (de)	1987-11-25	Desodorierungsmittel
DE69211127D1 (de)	1996-07-04	Neue flüssige zusammensetzungen auf basis von 1,4-substituierten piperidin-derivaten
SG44827A1 (en)	1997-12-19	Compounds useful as antiproliferative agents and garft inhibitors
TH19245A (th)	1996-06-21	วิธีป้องกันการสลายของโปรตีนซี
WO2001023366A3 (en)	2001-06-07	Vasopressin antagonist and diuretic combination