DK0739197T3 - Konserverede oftalmiske lægemiddelpræparater, som indeholder polymere kvaternære ammoniumforbindelser - Google Patents
Konserverede oftalmiske lægemiddelpræparater, som indeholder polymere kvaternære ammoniumforbindelserInfo
- Publication number
- DK0739197T3 DK0739197T3 DK95939996T DK95939996T DK0739197T3 DK 0739197 T3 DK0739197 T3 DK 0739197T3 DK 95939996 T DK95939996 T DK 95939996T DK 95939996 T DK95939996 T DK 95939996T DK 0739197 T3 DK0739197 T3 DK 0739197T3
- Authority
- DK
- Denmark
- Prior art keywords
- quaternary ammonium
- ammonium compounds
- polymeric quaternary
- preparations containing
- containing polymeric
- Prior art date
Links
- 150000003856 quaternary ammonium compounds Chemical class 0.000 title abstract 2
- 239000003732 agents acting on the eye Substances 0.000 title 1
- 229940023490 ophthalmic product Drugs 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 abstract 1
- 239000004327 boric acid Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/340,763 US5603929A (en) | 1994-11-16 | 1994-11-16 | Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds |
| PCT/US1995/014910 WO1996014829A1 (en) | 1994-11-16 | 1995-11-16 | Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0739197T3 true DK0739197T3 (da) | 2001-10-29 |
Family
ID=23334841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95939996T DK0739197T3 (da) | 1994-11-16 | 1995-11-16 | Konserverede oftalmiske lægemiddelpræparater, som indeholder polymere kvaternære ammoniumforbindelser |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5603929A (da) |
| EP (1) | EP0739197B1 (da) |
| JP (1) | JP2954356B2 (da) |
| AT (1) | ATE203897T1 (da) |
| AU (1) | AU686917B2 (da) |
| CA (1) | CA2180554C (da) |
| DE (1) | DE69522094T2 (da) |
| DK (1) | DK0739197T3 (da) |
| ES (1) | ES2160722T3 (da) |
| GR (1) | GR3036622T3 (da) |
| PT (1) | PT739197E (da) |
| WO (1) | WO1996014829A1 (da) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5505953A (en) | 1992-05-06 | 1996-04-09 | Alcon Laboratories, Inc. | Use of borate-polyol complexes in ophthalmic compositions |
| US5683993A (en) * | 1995-06-22 | 1997-11-04 | Ciba Vision Corporation | Compositions and methods for stabilizing polymers |
| EP0880351A4 (en) * | 1996-02-14 | 2003-01-08 | Alcon Lab Inc | Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobials |
| EP0877600B1 (en) * | 1996-08-09 | 2003-10-22 | Alcon Manufacturing Ltd. | Preservative systems for pharmaceutical compositions containing cyclodextrins |
| CA2272308C (en) | 1996-12-13 | 2007-01-16 | Alcon Laboratories, Inc. | Use of low molecular weight amino alcohols in ophthalmic compositions |
| ATE391492T1 (de) | 1997-07-29 | 2008-04-15 | Alcon Lab Inc | Ophthalmische zusammensetzungen enthaltend galaktomannanpolymere und borat |
| CN1769411A (zh) | 1997-11-26 | 2006-05-10 | 先进医用光学公司 | 护理接触镜片的多用途溶液 |
| US6063745A (en) | 1997-11-26 | 2000-05-16 | Allergan | Mutli-purpose contact lens care compositions |
| JPH11249087A (ja) * | 1997-12-18 | 1999-09-17 | Tome:Kk | コンタクトレンズ用液剤 |
| JP2006111636A (ja) * | 1997-12-26 | 2006-04-27 | Astellas Pharma Inc | 徐放性医薬組成物 |
| US7678836B2 (en) * | 1999-11-04 | 2010-03-16 | Fxs Ventures, Llc | Method for rendering a contact lens wettable |
| ATE291913T1 (de) | 2000-01-25 | 2005-04-15 | Alcon Inc | Antiallergische ophthalmische zubereitungen, geeignet zur anwendung mit kontaktlinsen |
| AR035509A1 (es) * | 2000-12-21 | 2004-06-02 | Alcon Inc | Solucion de lagrimas artificiales mejorada que contiene una combinacion de tres emolientes y el uso de dicha solucion para la fabricacion de un medicamento |
| US7923469B2 (en) * | 2001-04-30 | 2011-04-12 | Allergen, Inc. | Compositions including vitamin-based surfactants and methods for using same |
| JP4286480B2 (ja) * | 2001-09-17 | 2009-07-01 | 株式会社メニコン | 殺菌液 |
| US8129431B2 (en) * | 2003-01-21 | 2012-03-06 | Senju Pharmaceutical Co., Ltd. | Aqueous liquid preparation containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid |
| CA2505836C (en) * | 2004-05-06 | 2013-08-27 | Alcon Inc. | Topical brimonidine tartrate formulations that lack chlorine dioxide |
| US20060073184A1 (en) * | 2004-09-29 | 2006-04-06 | Bausch & Lomb Inc. | Viscoelastic composition, methods of use and packaging device with anti-oxidant |
| WO2006049250A1 (ja) | 2004-11-05 | 2006-05-11 | Senju Pharmaceutical Co., Ltd. | 眼内移行性促進水性点眼剤 |
| JP5108234B2 (ja) * | 2005-02-07 | 2012-12-26 | 日本特殊陶業株式会社 | マイクロヒータ及びセンサ |
| US7947010B2 (en) * | 2005-07-08 | 2011-05-24 | Depuy Products, Inc. | Composition and system for wound decontamination |
| US20100130580A1 (en) * | 2006-01-25 | 2010-05-27 | Aciex Therapeutics, Inc. | Formulations and Methods for Treating Dry Eye |
| US20090010850A1 (en) * | 2007-05-24 | 2009-01-08 | Ousler Iii George W | Formulations and methods for treating dry eye |
| CA2621616A1 (en) * | 2007-02-19 | 2008-08-19 | Alcon Research, Ltd. | Topical gatifloxacin formulations |
| US7705112B2 (en) * | 2007-04-17 | 2010-04-27 | Abbott Medical Optics Inc. | Polyquaternium-1 synthesis methods |
| US8435544B2 (en) | 2007-10-08 | 2013-05-07 | Lux Biosciences, Inc. | Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors |
| RU2010138799A (ru) * | 2008-02-21 | 2012-03-27 | Иста Фармасьютикалз (Us) | Офтальмологические нестероидные противовоспалительные средства в качестве адъювантов |
| RU2431469C1 (ru) * | 2008-03-03 | 2011-10-20 | Аллерган, Инк. | Композиции кеторолака трометамина для лечения или профилактики глазной боли |
| US9192571B2 (en) | 2008-03-03 | 2015-11-24 | Allergan, Inc. | Ketorolac tromethamine compositions for treating or preventing ocular pain |
| TWI544927B (zh) | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
| CN101959500A (zh) | 2008-03-17 | 2011-01-26 | 爱尔康研究有限公司 | 包含硼酸类化合物-多元醇络合物的水性药物组合物 |
| TWI454289B (zh) * | 2008-04-03 | 2014-10-01 | Alcon Res Ltd | 使用順式二醇的聚合物於抑制陽離子殺生物劑被吸收進入水凝膠生物材質中之用途 |
| TW201038295A (en) | 2009-04-17 | 2010-11-01 | Alcon Res Ltd | Aqueous ophthalmic compositions containing anionic therapeutic agents |
| WO2010144194A1 (en) | 2009-06-09 | 2010-12-16 | Lux Biosciences, Inc. | Topical drug delivery systems for ophthalmic use |
| TWI489997B (zh) * | 2009-06-19 | 2015-07-01 | Alcon Res Ltd | 含有硼酸-多元醇錯合物之水性藥學組成物 |
| MX341189B (es) | 2011-01-18 | 2016-08-09 | Senju Pharma Co | Composicion liquida y acousa de bromfenaco, que tiene efectividad conservadora. |
| PL2919755T3 (pl) * | 2012-11-19 | 2018-07-31 | Bausch & Lomb Incorporated | Wodna ciekła kompozycja zawierająca kwas 2-amino-3-(4-bromobenzoilo)fenylooctowy |
| US20160143869A1 (en) | 2013-06-19 | 2016-05-26 | Sentiss Research Center | Stable bromfenac solution |
| BR112016003692B1 (pt) | 2013-08-20 | 2022-02-08 | 3M Innovative Properties Company | Complexo poliéter boro-silano |
| US20170000889A1 (en) | 2013-12-12 | 2017-01-05 | Sentiss Pharma Private Limited | Stable bromfenac ophthalmic solution |
| US10632202B2 (en) | 2016-03-04 | 2020-04-28 | Johnson & Johnson Consumer Inc. | Preservative containing compositions |
| US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
| US20230159202A1 (en) * | 2021-11-23 | 2023-05-25 | Bausch + Lomb Ireland Limited | Method for making a preservative-free packaged ophthalmic device product |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4027020A (en) * | 1974-10-29 | 1977-05-31 | Millmaster Onyx Corporation | Randomly terminated capped polymers |
| US3931319A (en) * | 1974-10-29 | 1976-01-06 | Millmaster Onyx Corporation | Capped polymers |
| US4136177A (en) * | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Xanthan gum therapeutic compositions |
| US4136178A (en) * | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Locust bean gum therapeutic compositions |
| US4136173A (en) * | 1977-01-31 | 1979-01-23 | American Home Products Corp. | Mixed xanthan gum and locust beam gum therapeutic compositions |
| FR2508440B1 (fr) * | 1981-06-25 | 1985-11-08 | Saint Gobain Isover | Procede de preparation d'alcools orthohydroxybenzyliques |
| US4525346A (en) * | 1981-09-28 | 1985-06-25 | Alcon Laboratories, Inc. | Aqueous antimicrobial ophthalmic solutions |
| US4407791A (en) * | 1981-09-28 | 1983-10-04 | Alcon Laboratories, Inc. | Ophthalmic solutions |
| US4836986A (en) * | 1984-09-28 | 1989-06-06 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
| FR2588189B1 (fr) * | 1985-10-03 | 1988-12-02 | Merck Sharp & Dohme | Composition pharmaceutique de type a transition de phase liquide-gel |
| US4822819A (en) * | 1986-11-07 | 1989-04-18 | Alcon Laboratories, Inc. | Use of trimoprostil and derivatives in glaucoma therapy |
| US4822820A (en) * | 1986-11-24 | 1989-04-18 | Alcon Laboratories, Inc. | Use of tri-methyl PG-F2 a and derivatives in glaucoma therapy |
| AU626798B2 (en) * | 1987-09-11 | 1992-08-13 | Syntex (U.S.A.) Llc | Preservative system for ophthalmic formulations |
| US5110493A (en) * | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
| IE63392B1 (en) * | 1988-02-08 | 1995-04-19 | Insite Vision Inc | Ophthalmic suspensions |
| US5188826A (en) * | 1988-02-08 | 1993-02-23 | Insite Vision Incorporated | Topical ophthalmic suspensions |
| US5149693A (en) * | 1988-03-09 | 1992-09-22 | Alcon Laboratories, Inc. | Combination of tobramycin and fluorometholone for topical ophthalmic use |
| US5149694A (en) * | 1988-03-09 | 1992-09-22 | Alcon Laboratories, Inc. | Combination of tobramycin and dexamethasone for topical ophthalmic use |
| US5173507A (en) * | 1988-07-18 | 1992-12-22 | Alcon Laboratories, Inc. | Prostaglandin combinations in glaucoma therapy |
| US4960799A (en) * | 1988-09-13 | 1990-10-02 | Ciba-Geigy Corporation | Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use |
| US5037647A (en) * | 1988-09-15 | 1991-08-06 | Alcon Laboratories, Inc. | Aqueous antimicrobial opthalmic solutions comprised of quaternary ammonium compound, citric acid, citrate and sodium chloride |
| US5145643A (en) * | 1990-01-05 | 1992-09-08 | Allergan, Inc. | Nonoxidative ophthalmic compositions and methods for preserving and using same |
| DK0639070T4 (da) * | 1992-05-06 | 2010-12-13 | Alcon Lab Inc | Anvendelse af borat-polyolkomplekser til ophtalmiske præparater |
| US5300287A (en) * | 1992-11-04 | 1994-04-05 | Alcon Laboratories, Inc. | Polymeric antimicrobials and their use in pharmaceutical compositions |
| AU6021794A (en) * | 1993-01-11 | 1994-08-15 | Allergan, Inc. | Ophthalmic compositions comprising benzyllauryldimethylammonium chloride |
-
1994
- 1994-11-16 US US08/340,763 patent/US5603929A/en not_active Expired - Lifetime
-
1995
- 1995-11-16 DE DE69522094T patent/DE69522094T2/de not_active Expired - Lifetime
- 1995-11-16 PT PT95939996T patent/PT739197E/pt unknown
- 1995-11-16 EP EP95939996A patent/EP0739197B1/en not_active Expired - Lifetime
- 1995-11-16 AT AT95939996T patent/ATE203897T1/de active
- 1995-11-16 ES ES95939996T patent/ES2160722T3/es not_active Expired - Lifetime
- 1995-11-16 JP JP8509750A patent/JP2954356B2/ja not_active Expired - Lifetime
- 1995-11-16 AU AU41622/96A patent/AU686917B2/en not_active Expired
- 1995-11-16 DK DK95939996T patent/DK0739197T3/da active
- 1995-11-16 CA CA002180554A patent/CA2180554C/en not_active Expired - Lifetime
- 1995-11-16 WO PCT/US1995/014910 patent/WO1996014829A1/en not_active Ceased
-
1996
- 1996-08-21 US US08/700,960 patent/US5653972A/en not_active Expired - Lifetime
-
2001
- 2001-09-17 GR GR20010401480T patent/GR3036622T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2954356B2 (ja) | 1999-09-27 |
| PT739197E (pt) | 2001-12-28 |
| CA2180554A1 (en) | 1996-05-23 |
| JPH09503791A (ja) | 1997-04-15 |
| GR3036622T3 (en) | 2001-12-31 |
| HK1012556A1 (en) | 1999-08-06 |
| US5603929A (en) | 1997-02-18 |
| EP0739197A1 (en) | 1996-10-30 |
| EP0739197B1 (en) | 2001-08-08 |
| ATE203897T1 (de) | 2001-08-15 |
| AU686917B2 (en) | 1998-02-12 |
| ES2160722T3 (es) | 2001-11-16 |
| US5653972A (en) | 1997-08-05 |
| CA2180554C (en) | 2001-08-21 |
| WO1996014829A1 (en) | 1996-05-23 |
| DE69522094D1 (de) | 2001-09-13 |
| AU4162296A (en) | 1996-06-06 |
| DE69522094T2 (de) | 2001-11-22 |
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