DK0739229T3 - Massefyldegradientmedium til seperation af celler - Google Patents
Massefyldegradientmedium til seperation af cellerInfo
- Publication number
- DK0739229T3 DK0739229T3 DK95910120T DK95910120T DK0739229T3 DK 0739229 T3 DK0739229 T3 DK 0739229T3 DK 95910120 T DK95910120 T DK 95910120T DK 95910120 T DK95910120 T DK 95910120T DK 0739229 T3 DK0739229 T3 DK 0739229T3
- Authority
- DK
- Denmark
- Prior art keywords
- density gradient
- gradient medium
- cell separation
- medium
- blood cells
- Prior art date
Links
- 238000000926 separation method Methods 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 210000003743 erythrocyte Anatomy 0.000 abstract 1
- 210000004700 fetal blood Anatomy 0.000 abstract 1
- 230000001605 fetal effect Effects 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 230000008774 maternal effect Effects 0.000 abstract 1
- 210000003924 normoblast Anatomy 0.000 abstract 1
- 210000005259 peripheral blood Anatomy 0.000 abstract 1
- 239000011886 peripheral blood Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
- B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Ecology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Sampling And Sample Adjustment (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/189,509 US5489386A (en) | 1994-01-31 | 1994-01-31 | Density gradient medium for the separation of cells |
| PCT/US1995/000956 WO1995020429A1 (en) | 1994-01-31 | 1995-01-23 | Density gradient medium for separating cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0739229T3 true DK0739229T3 (da) | 2002-02-25 |
Family
ID=22697630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95910120T DK0739229T3 (da) | 1994-01-31 | 1995-01-23 | Massefyldegradientmedium til seperation af celler |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5489386A (da) |
| EP (1) | EP0739229B1 (da) |
| JP (1) | JP3017291B2 (da) |
| AT (1) | ATE207777T1 (da) |
| AU (1) | AU680738B2 (da) |
| CA (1) | CA2182367C (da) |
| DE (1) | DE69523566T2 (da) |
| DK (1) | DK0739229T3 (da) |
| WO (1) | WO1995020429A1 (da) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI940823A0 (fi) * | 1994-02-22 | 1994-02-22 | Orion Yhtymae Oy | Analysatorkyvett foer turbidimetriska och nefelometriska bestaemningar av helblodsprov |
| ES2189869T3 (es) * | 1995-03-08 | 2003-07-16 | Bioseparations Inc | Procedimiento para el enriquecimiento de poblaciones de celulas raras. |
| US5639669A (en) * | 1995-06-07 | 1997-06-17 | Ledley; Robert | Separation of fetal cells from maternal blood |
| AUPN883396A0 (en) * | 1996-03-21 | 1996-04-18 | Australian Red Cross Society (Western Australian Division) | Centrifugation support |
| US6210889B1 (en) | 1998-01-28 | 2001-04-03 | The Universite Laval | Method for enrichment of fetal cells from maternal blood and use of same in determination of fetal sex and detection of chromosomal abnormalities |
| US6535393B2 (en) * | 1998-12-04 | 2003-03-18 | Micron Technology, Inc. | Electrical device allowing for increased device densities |
| IT1311989B1 (it) * | 1999-03-30 | 2002-03-22 | Giammaria Sitar | Procedimento per isolare cellule fetali presenti nel sangue perifericomaterno. |
| US7135335B2 (en) * | 1999-05-28 | 2006-11-14 | Stemcell Technologies Inc. | Method for separating cells using immunorosettes |
| US7947236B2 (en) | 1999-12-03 | 2011-05-24 | Becton, Dickinson And Company | Device for separating components of a fluid sample |
| CA2439748A1 (en) | 2001-03-07 | 2002-09-19 | The Texas A & M University System | Density gradient solutions of metal ion chelate complexes |
| US7316932B2 (en) * | 2001-10-01 | 2008-01-08 | Stemcell Technologies Inc. | Method for separating cells |
| RU2271009C2 (ru) * | 2003-12-15 | 2006-02-27 | Юлия Владимировна Шеверева | Способ фракционирования эритроцитов в градиенте плотности раствора агарозы |
| US7653260B2 (en) * | 2004-06-17 | 2010-01-26 | Carl Zeis MicroImaging GmbH | System and method of registering field of view |
| US8582924B2 (en) * | 2004-06-30 | 2013-11-12 | Carl Zeiss Microimaging Gmbh | Data structure of an image storage and retrieval system |
| US20060051265A1 (en) * | 2004-09-08 | 2006-03-09 | Health Research, Inc. | Apparatus and method for sorting microstructures in a fluid medium |
| US7674388B2 (en) * | 2005-08-10 | 2010-03-09 | The Regents Of The University Of California | Photopolymer serum separator |
| US7673758B2 (en) * | 2005-08-10 | 2010-03-09 | The Regents Of The University Of California | Collection tubes apparatus, systems, and methods |
| US7971730B2 (en) | 2005-08-10 | 2011-07-05 | The Regents Of The University Of California | Collection tubes apparatus, systems and methods |
| US9248447B2 (en) * | 2005-08-10 | 2016-02-02 | The Regents Of The University Of California | Polymers for use in centrifugal separation of liquids |
| US20070238088A1 (en) * | 2006-03-29 | 2007-10-11 | General Electric Company | Hydrophilic functionalized colloidal silica compositions, methods of making, and uses therefor |
| WO2008143849A2 (en) * | 2007-05-14 | 2008-11-27 | Historx, Inc. | Compartment segregation by pixel characterization using image data clustering |
| WO2008156669A1 (en) * | 2007-06-15 | 2008-12-24 | Historx, Inc. | Method and system for standardizing microscope instruments |
| CA2604317C (en) | 2007-08-06 | 2017-02-28 | Historx, Inc. | Methods and system for validating sample images for quantitative immunoassays |
| CA2596204C (en) * | 2007-08-07 | 2019-02-26 | Historx, Inc. | Method and system for determining an optimal dilution of a reagent |
| WO2009029810A1 (en) * | 2007-08-31 | 2009-03-05 | Historx, Inc. | Automatic exposure time selection for imaging tissue |
| WO2010011672A2 (en) | 2008-07-21 | 2010-01-28 | Becton, Dickinson And Company | Density phase separation device |
| CA2731076C (en) | 2008-07-21 | 2013-06-11 | Becton, Dickinson And Company | Density phase separation device |
| CA2731155C (en) | 2008-07-21 | 2013-09-24 | Becton, Dickinson And Company | Density phase separation device |
| US20100159506A1 (en) * | 2008-07-25 | 2010-06-24 | Cellscape Corporation | Methods and systems for genetic analysis of fetal nucleated red blood cells |
| WO2010033508A1 (en) * | 2008-09-16 | 2010-03-25 | Historx, Inc. | Reproducible quantification of biomarker expression |
| ES2763364T3 (es) | 2009-05-15 | 2020-05-28 | Becton Dickinson Co | Dispositivo de separación de fase de densidad |
| US9272083B2 (en) | 2009-05-29 | 2016-03-01 | Endocellutions, Inc. | Apparatus and methods for aspirating and separating components of different densities from a physiological fluid containing cells |
| BR112012018166A2 (pt) | 2010-01-21 | 2015-09-15 | Biocep Ltd | separação magnética de células raras. |
| NL1037672C2 (nl) * | 2010-02-01 | 2011-08-03 | Eurotrol B V | Werkwijze voor het bepalen van de betrouwbaarheid van een inrichting voor het meten van de concentratie van een stof in volledig bloed, werkwijze voor het behandelen van volledig bloed, houder en kit. |
| US8774488B2 (en) | 2010-03-11 | 2014-07-08 | Cellscape Corporation | Method and device for identification of nucleated red blood cells from a maternal blood sample |
| WO2012023298A1 (ja) * | 2010-08-20 | 2012-02-23 | 国立大学法人北陸先端科学技術大学院大学 | 血球の密度変化を利用した密度勾配遠心による有核赤血球の回収法 |
| JP6208473B2 (ja) | 2012-06-20 | 2017-10-04 | アークレイ株式会社 | 血液成分を含む試料の処理方法 |
| US9669405B2 (en) | 2012-10-22 | 2017-06-06 | The Regents Of The University Of California | Sterilizable photopolymer serum separator |
| US9217697B2 (en) | 2012-11-30 | 2015-12-22 | Rarecyte, Inc. | Apparatus, system, and method for collecting a target material |
| US10603665B2 (en) | 2013-01-29 | 2020-03-31 | Endocellutions, Inc. | Cell concentration devices and methods that include an insert defining a lumen and a cannula assembly |
| US9694359B2 (en) | 2014-11-13 | 2017-07-04 | Becton, Dickinson And Company | Mechanical separator for a biological fluid |
| EP3573759A4 (en) | 2017-01-25 | 2020-07-29 | Yantai AusBio Laboratories Co., Ltd. | EQUIPMENT AND METHOD FOR AUTOMATIC SAMPLING FOR DIAGNOSTIC PURPOSES |
| USD898184S1 (en) | 2019-01-29 | 2020-10-06 | Handi-Craft Company | Breast pump valve |
| US11738288B2 (en) | 2020-06-29 | 2023-08-29 | Jacques Chammas | Automated system and method to isolate specific cells from blood or bone marrow |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4049692A (en) * | 1974-12-16 | 1977-09-20 | Corning Glass Works | Stabilized blood separating composition |
| US4101422A (en) * | 1977-05-11 | 1978-07-18 | Emery Industries, Inc. | Copolyesters useful in blood separation assemblies |
| US4386003A (en) * | 1981-09-17 | 1983-05-31 | Sherwood Medical Industries Inc. | Blood separating composition |
| US4416778A (en) * | 1981-10-20 | 1983-11-22 | Neocyte, Inc. | Means for preparing neocyte enriched blood |
| US4797475A (en) * | 1983-05-20 | 1989-01-10 | The Regents Of The University Of California | Method and composition for isolating white cell elements |
| US4751001A (en) * | 1984-09-24 | 1988-06-14 | Becton Dickinson And Company | Blood partitioning apparatus |
| US4818418A (en) * | 1984-09-24 | 1989-04-04 | Becton Dickinson And Company | Blood partitioning method |
| US5053134A (en) * | 1984-12-04 | 1991-10-01 | Becton Dickinson And Company | Lymphocyte collection tube |
| US4917801A (en) * | 1984-12-04 | 1990-04-17 | Becton Dickinson And Company | Lymphocyte collection tube |
| US5260186A (en) * | 1986-03-10 | 1993-11-09 | Boris Cercek | Provision of density specific blood cells for the structuredness of the cytoplasmic matrix (SCM) test |
| US4927750A (en) * | 1986-04-09 | 1990-05-22 | Jeanette Simpson | Cell separation process |
| US4835097A (en) * | 1986-10-15 | 1989-05-30 | Saunders Alexander M | Method for ascertaining the history of a condition of the body from a single blood sample |
| EP0353587A3 (en) * | 1988-07-26 | 1992-07-29 | Nippon Paint Co., Ltd. | Serum separation sealant and fine resin particles used in the same |
| JPH05501612A (ja) * | 1989-11-13 | 1993-03-25 | チルドレンズ・メデイカル・センター・コーポレーシヨン | 胎児dna単離および検出のための非侵入性方法 |
| JPH05507404A (ja) * | 1990-04-23 | 1993-10-28 | セルプロ インコーポレイティド | 母体血液からの胎児細胞の富化のための方法 |
| DE4222573C1 (da) * | 1992-05-16 | 1993-08-12 | Dorothee Dr. 4400 Muenster De Ahlert | |
| US5275933A (en) * | 1992-09-25 | 1994-01-04 | The Board Of Trustees Of The Leland Stanford Junior University | Triple gradient process for recovering nucleated fetal cells from maternal blood |
| FR2963384B1 (fr) | 2010-07-30 | 2012-08-31 | Turbomeca | Dispositif de commande d'aubes pivotantes de turbomachine |
-
1994
- 1994-01-31 US US08/189,509 patent/US5489386A/en not_active Expired - Lifetime
-
1995
- 1995-01-23 WO PCT/US1995/000956 patent/WO1995020429A1/en not_active Ceased
- 1995-01-23 DK DK95910120T patent/DK0739229T3/da active
- 1995-01-23 CA CA002182367A patent/CA2182367C/en not_active Expired - Fee Related
- 1995-01-23 AU AU18337/95A patent/AU680738B2/en not_active Ceased
- 1995-01-23 EP EP95910120A patent/EP0739229B1/en not_active Expired - Lifetime
- 1995-01-23 DE DE69523566T patent/DE69523566T2/de not_active Expired - Fee Related
- 1995-01-23 JP JP7520133A patent/JP3017291B2/ja not_active Expired - Lifetime
- 1995-01-23 AT AT95910120T patent/ATE207777T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| DE69523566T2 (de) | 2002-09-05 |
| US5489386A (en) | 1996-02-06 |
| EP0739229A4 (en) | 1997-12-03 |
| EP0739229B1 (en) | 2001-10-31 |
| JP3017291B2 (ja) | 2000-03-06 |
| EP0739229A1 (en) | 1996-10-30 |
| WO1995020429A1 (en) | 1995-08-03 |
| CA2182367C (en) | 2002-07-09 |
| JPH09508971A (ja) | 1997-09-09 |
| DE69523566D1 (de) | 2001-12-06 |
| AU680738B2 (en) | 1997-08-07 |
| CA2182367A1 (en) | 1995-08-03 |
| ATE207777T1 (de) | 2001-11-15 |
| AU1833795A (en) | 1995-08-15 |
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