DK0741746T3 - Thymosin alpha 1-analoger - Google Patents

Thymosin alpha 1-analoger

Info

Publication number: DK0741746T3
Authority: DK; Denmark
Prior art keywords: analogues; thymosin alpha; thymosin; compounds; synthesis
Prior art date: 1994-01-28

Application number

DK95907463T

Other languages

English (en)

Inventor

Su-Sun Wang

Original Assignee

Sciclone Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-28

Filing date

1995-01-18

Publication date

2006-05-29

1995-01-18 Application filed by Sciclone Pharmaceuticals Inc filed Critical Sciclone Pharmaceuticals Inc

2006-05-29 Application granted granted Critical

2006-05-29 Publication of DK0741746T3 publication Critical patent/DK0741746T3/da

Links

NZVYCXVTEHPMHE-ZSUJOUNUSA-N thymalfasin Chemical class CC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O NZVYCXVTEHPMHE-ZSUJOUNUSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
102000007501 Thymosin Human genes 0.000 abstract 1
108010046075 Thymosin Proteins 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
210000000987 immune system Anatomy 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
LCJVIYPJPCBWKS-NXPQJCNCSA-N thymosin Chemical compound SC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CO)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(O)=O)C(O)=O LCJVIYPJPCBWKS-NXPQJCNCSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57581—Thymosin; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Compression, Expansion, Code Conversion, And Decoders (AREA)
Semiconductor Integrated Circuits (AREA)
Saccharide Compounds (AREA)

DK95907463T 1994-01-28 1995-01-18 Thymosin alpha 1-analoger DK0741746T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/188,232 US6262230B1 (en)	1994-01-28	1994-01-28	Analogs of thymosin α1

Publications (1)

Publication Number	Publication Date
DK0741746T3 true DK0741746T3 (da)	2006-05-29

Family

ID=22692289

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95907463T DK0741746T3 (da)	1994-01-28	1995-01-18	Thymosin alpha 1-analoger

Country Status (15)

Country	Link
US (1)	US6262230B1 (da)
EP (2)	EP1688431A3 (da)
JP (2)	JPH09508387A (da)
AT (1)	ATE315583T1 (da)
AU (1)	AU1568995A (da)
CA (1)	CA2181477C (da)
DE (1)	DE69534740T2 (da)
DK (1)	DK0741746T3 (da)
ES (1)	ES2259439T3 (da)
MY (1)	MY114151A (da)
PE (1)	PE29797A1 (da)
PT (1)	PT741746E (da)
TW (1)	TW396161B (da)
WO (1)	WO1995020602A2 (da)
ZA (1)	ZA95669B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101166761A (zh) *	2005-05-04	2008-04-23	隆萨股份公司	肽合成法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL176255C (nl) *	1971-07-01	1985-03-18	Hoechst Ag	Werkwijze voor het bereiden van peptiden.
US4079127A (en)	1976-10-28	1978-03-14	Board Of Regents Of The University Of Texas	Thymosin alpha 1
CH641152A5 (en) *	1977-04-22	1984-02-15	Hoffmann La Roche	Process for preparing thymosin alpha-1 and an analogue
US4116951A (en)	1977-04-22	1978-09-26	Hoffmann-La Roche Inc.	[Asn2 ]-thymosin α1 and analogs thereof
US4148788A (en)	1978-01-23	1979-04-10	Hoffmann-La Roche Inc.	Synthesis of thymosin α1
DE2919592A1 (de) *	1979-05-15	1981-01-15	Max Planck Gesellschaft	Verfahren zur herstellung von thymosin- alpha 1 und derivaten davon
DE3100974A1 (de) *	1980-01-18	1982-01-21	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen	Thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-fragmente enthaltende arzneimittel mit immunregulierender wirkung, und thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-fragmente
US4612365A (en) *	1980-03-25	1986-09-16	Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften	Medicaments containing alpha 1-thymosin and having an immuno regulatory action and alpha 1-thymosin fragments
US4659694A (en) *	1983-10-27	1987-04-21	Hoffmann-La Roche Inc.	Prothymosin alpha
US4855407A (en) *	1985-04-11	1989-08-08	Alpha-1 Biomedicals, Inc.	Solid phase process for synthesizing peptides
ATE136551T1 (de) *	1988-05-10	1996-04-15	Alpha 1 Biomedicals Inc	Festphase-verfahren zur gewinnung von thymosin- alpha-1

1994
- 1994-01-28 US US08/188,232 patent/US6262230B1/en not_active Expired - Fee Related
- 1994-01-31 TW TW083100771A patent/TW396161B/zh not_active IP Right Cessation
1995
- 1995-01-18 DE DE69534740T patent/DE69534740T2/de not_active Expired - Fee Related
- 1995-01-18 PT PT95907463T patent/PT741746E/pt unknown
- 1995-01-18 JP JP7520088A patent/JPH09508387A/ja not_active Ceased
- 1995-01-18 CA CA002181477A patent/CA2181477C/en not_active Expired - Fee Related
- 1995-01-18 EP EP06000390A patent/EP1688431A3/en not_active Withdrawn
- 1995-01-18 WO PCT/US1995/000617 patent/WO1995020602A2/en not_active Ceased
- 1995-01-18 PE PE1995259687A patent/PE29797A1/es not_active Application Discontinuation
- 1995-01-18 AU AU15689/95A patent/AU1568995A/en not_active Abandoned
- 1995-01-18 AT AT95907463T patent/ATE315583T1/de not_active IP Right Cessation
- 1995-01-18 ES ES95907463T patent/ES2259439T3/es not_active Expired - Lifetime
- 1995-01-18 EP EP95907463A patent/EP0741746B1/en not_active Expired - Lifetime
- 1995-01-18 DK DK95907463T patent/DK0741746T3/da active
- 1995-01-26 MY MYPI95000180A patent/MY114151A/en unknown
- 1995-01-27 ZA ZA95669A patent/ZA95669B/xx unknown
2006
- 2006-01-25 JP JP2006016059A patent/JP3931194B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
TW396161B (en)	2000-07-01
PE29797A1 (es)	1997-09-01
EP1688431A2 (en)	2006-08-09
CA2181477C (en)	2002-01-01
DE69534740D1 (en)	2006-04-06
EP1688431A3 (en)	2006-11-29
US6262230B1 (en)	2001-07-17
HK1013296A1 (en)	1999-08-20
WO1995020602A3 (en)	1995-10-12
ES2259439T3 (es)	2006-10-01
DE69534740T2 (de)	2006-11-02
JPH09508387A (ja)	1997-08-26
PT741746E (pt)	2006-05-31
EP0741746B1 (en)	2006-01-11
JP2006160751A (ja)	2006-06-22
AU1568995A (en)	1995-08-15
ZA95669B (en)	1996-07-29
ATE315583T1 (de)	2006-02-15
WO1995020602A2 (en)	1995-08-03
EP0741746A1 (en)	1996-11-13
JP3931194B2 (ja)	2007-06-13
CA2181477A1 (en)	1995-08-03
MY114151A (en)	2002-08-30

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