ZA95669B - Analogs of thymosin alpha1 - Google Patents

Analogs of thymosin alpha1

Info

Publication number: ZA95669B
Authority: ZA; South Africa
Prior art keywords: analogs; thymosin; thymosin alpha1; alpha1; compounds
Prior art date: 1994-01-28

Application number

ZA95669A

Other languages

English (en)

Inventor

Su-Sun Wang

Original Assignee

Alpha 1 Biomedicals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-28

Filing date

1995-01-27

Publication date

1996-07-29

1995-01-27 Application filed by Alpha 1 Biomedicals Inc filed Critical Alpha 1 Biomedicals Inc

1996-07-29 Publication of ZA95669B publication Critical patent/ZA95669B/xx

Links

108010078233 Thymalfasin Proteins 0.000 title 1
102400000800 Thymosin alpha-1 Human genes 0.000 title 1
NZVYCXVTEHPMHE-ZSUJOUNUSA-N thymalfasin Chemical compound CC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O NZVYCXVTEHPMHE-ZSUJOUNUSA-N 0.000 title 1
229960004231 thymalfasin Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
102000007501 Thymosin Human genes 0.000 abstract 1
108010046075 Thymosin Proteins 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
210000000987 immune system Anatomy 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1
LCJVIYPJPCBWKS-NXPQJCNCSA-N thymosin Chemical compound SC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CO)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@H]([C@H](C)O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](C(C)C)C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(O)=O)C(O)=O LCJVIYPJPCBWKS-NXPQJCNCSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57581—Thymosin; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Compression, Expansion, Code Conversion, And Decoders (AREA)
Semiconductor Integrated Circuits (AREA)
Saccharide Compounds (AREA)

ZA95669A 1994-01-28 1995-01-27 Analogs of thymosin alpha1 ZA95669B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/188,232 US6262230B1 (en)	1994-01-28	1994-01-28	Analogs of thymosin α1

Publications (1)

Publication Number	Publication Date
ZA95669B true ZA95669B (en)	1996-07-29

Family

ID=22692289

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA95669A ZA95669B (en)	1994-01-28	1995-01-27	Analogs of thymosin alpha1

Country Status (15)

Country	Link
US (1)	US6262230B1 (da)
EP (2)	EP1688431A3 (da)
JP (2)	JPH09508387A (da)
AT (1)	ATE315583T1 (da)
AU (1)	AU1568995A (da)
CA (1)	CA2181477C (da)
DE (1)	DE69534740T2 (da)
DK (1)	DK0741746T3 (da)
ES (1)	ES2259439T3 (da)
MY (1)	MY114151A (da)
PE (1)	PE29797A1 (da)
PT (1)	PT741746E (da)
TW (1)	TW396161B (da)
WO (1)	WO1995020602A2 (da)
ZA (1)	ZA95669B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101166761A (zh) *	2005-05-04	2008-04-23	隆萨股份公司	肽合成法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL176255C (nl) *	1971-07-01	1985-03-18	Hoechst Ag	Werkwijze voor het bereiden van peptiden.
US4079127A (en)	1976-10-28	1978-03-14	Board Of Regents Of The University Of Texas	Thymosin alpha 1
CH641152A5 (en) *	1977-04-22	1984-02-15	Hoffmann La Roche	Process for preparing thymosin alpha-1 and an analogue
US4116951A (en)	1977-04-22	1978-09-26	Hoffmann-La Roche Inc.	[Asn2 ]-thymosin α1 and analogs thereof
US4148788A (en)	1978-01-23	1979-04-10	Hoffmann-La Roche Inc.	Synthesis of thymosin α1
DE2919592A1 (de) *	1979-05-15	1981-01-15	Max Planck Gesellschaft	Verfahren zur herstellung von thymosin- alpha 1 und derivaten davon
DE3100974A1 (de) *	1980-01-18	1982-01-21	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen	Thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-fragmente enthaltende arzneimittel mit immunregulierender wirkung, und thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-fragmente
US4612365A (en) *	1980-03-25	1986-09-16	Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften	Medicaments containing alpha 1-thymosin and having an immuno regulatory action and alpha 1-thymosin fragments
US4659694A (en) *	1983-10-27	1987-04-21	Hoffmann-La Roche Inc.	Prothymosin alpha
US4855407A (en) *	1985-04-11	1989-08-08	Alpha-1 Biomedicals, Inc.	Solid phase process for synthesizing peptides
ATE136551T1 (de) *	1988-05-10	1996-04-15	Alpha 1 Biomedicals Inc	Festphase-verfahren zur gewinnung von thymosin- alpha-1

1994
- 1994-01-28 US US08/188,232 patent/US6262230B1/en not_active Expired - Fee Related
- 1994-01-31 TW TW083100771A patent/TW396161B/zh not_active IP Right Cessation
1995
- 1995-01-18 DE DE69534740T patent/DE69534740T2/de not_active Expired - Fee Related
- 1995-01-18 PT PT95907463T patent/PT741746E/pt unknown
- 1995-01-18 JP JP7520088A patent/JPH09508387A/ja not_active Ceased
- 1995-01-18 CA CA002181477A patent/CA2181477C/en not_active Expired - Fee Related
- 1995-01-18 EP EP06000390A patent/EP1688431A3/en not_active Withdrawn
- 1995-01-18 WO PCT/US1995/000617 patent/WO1995020602A2/en not_active Ceased
- 1995-01-18 PE PE1995259687A patent/PE29797A1/es not_active Application Discontinuation
- 1995-01-18 AU AU15689/95A patent/AU1568995A/en not_active Abandoned
- 1995-01-18 AT AT95907463T patent/ATE315583T1/de not_active IP Right Cessation
- 1995-01-18 ES ES95907463T patent/ES2259439T3/es not_active Expired - Lifetime
- 1995-01-18 EP EP95907463A patent/EP0741746B1/en not_active Expired - Lifetime
- 1995-01-18 DK DK95907463T patent/DK0741746T3/da active
- 1995-01-26 MY MYPI95000180A patent/MY114151A/en unknown
- 1995-01-27 ZA ZA95669A patent/ZA95669B/xx unknown
2006
- 2006-01-25 JP JP2006016059A patent/JP3931194B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
TW396161B (en)	2000-07-01
PE29797A1 (es)	1997-09-01
EP1688431A2 (en)	2006-08-09
CA2181477C (en)	2002-01-01
DE69534740D1 (en)	2006-04-06
EP1688431A3 (en)	2006-11-29
US6262230B1 (en)	2001-07-17
HK1013296A1 (en)	1999-08-20
WO1995020602A3 (en)	1995-10-12
ES2259439T3 (es)	2006-10-01
DE69534740T2 (de)	2006-11-02
JPH09508387A (ja)	1997-08-26
PT741746E (pt)	2006-05-31
EP0741746B1 (en)	2006-01-11
JP2006160751A (ja)	2006-06-22
AU1568995A (en)	1995-08-15
ATE315583T1 (de)	2006-02-15
WO1995020602A2 (en)	1995-08-03
EP0741746A1 (en)	1996-11-13
JP3931194B2 (ja)	2007-06-13
CA2181477A1 (en)	1995-08-03
DK0741746T3 (da)	2006-05-29
MY114151A (en)	2002-08-30

Publication	Publication Date	Title
IT1236831B (it)	1993-04-21	Apparecchio per il trattamento dell'intestino in particolare per enteroclisma
MA21682A1 (fr)	1990-07-01	Procede de preparation d'agents therapeutiques derives de la quainclidine.
GB2247837B (en)	1992-10-28	Pharmaceutical product for the treatment of immunoregulatory disorders
SG55090A1 (en)	1998-12-21	3-Arylcarbonyl-1H-indoles useful as therapeutic agents
ZA928162B (en)	1993-05-05	Antibodies in immunosuppression.
FR2720070B1 (fr)	1997-01-17	Procédé de préparation d'alkylpolysiloxanes pontés et alkylpolysiloxanes pontés.
FI961378L (fi)	1996-03-26	Menetelmä N-metyyli-3-(1-metyyli-4-piperidinyyli)-14-indoli-5-etaanisulfonamidin valmistamiseksi
GB2216416B (en)	1992-06-24	Nucleobase source for the stimulation of the immune system
FR2708266B1 (fr)	1997-01-10	Procédé de préparation d'alcanesulfonamides.
IL89430A0 (en)	1989-09-10	Process for the preparation of 4,4'-dibromodiphenyl
EP0372282A3 (en)	1990-08-08	Process for the preparation of 1,5-dihydroxy and 1,5 diaminonaphthalene
GB9013868D0 (en)	1990-08-15	Spinal traction machine for self-application of traction
ZA929879B (en)	1993-07-02	Compositions for the treatment of mammalian diseases.
FR2620702B1 (fr)	1990-02-02	Procede de preparation d'irones naturelles
AU1568995A (en)	1995-08-15	Analogs of thymosin alpha1
EP0534449A3 (en)	1993-06-02	Process for the preparation of 3-aminomethyl-3,5,5-trialkylcyclohexylamine
ITMI931371A0 (it)	1993-06-25	Procedimento per la preparazione dell'erdosteina
ITMI942673A0 (it)	1994-12-29	Precesso per la (co) polinerizzazione dell'etilene
DE69305883D1 (de)	1996-12-19	Verfahren zur Herstellung von 2,6-Dimethylnaphthalin
AR245225A1 (es)	1993-12-30	Composiciones para el tratamiento de cuero.
EP0412938A3 (en)	1992-04-01	System for the treatment of contactlenses
GB9016062D0 (en)	1990-09-05	Process for the preparation of acrylates
FR2616038B1 (fr)	1990-12-21	Appareil pour l'etude de la photosynthese
IT1243274B (it)	1994-05-26	Procedimento per l'applicazione dello sperone e calzature costruite secondo il procedimento.
CS267587A1 (en)	1990-06-13	Equipment for materials' dynamic treatment