DK0751769T3 - Medicinsk behandling under anvendelse af skjoldbruskhormoner - Google Patents

Medicinsk behandling under anvendelse af skjoldbruskhormoner

Info

Publication number: DK0751769T3
Authority: DK; Denmark
Prior art keywords: medical treatment; thyroid hormones; treatment; diiodothyronine; liothyronine
Prior art date: 1993-06-22

Application number

DK94921305T

Other languages

Danish (da)

English (en)

Inventor

Gilbert H Mayor

Alecy Louis G D

Original Assignee

Univ Michigan

Knoll Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-22

Filing date

1994-06-22

Publication date

2003-04-07

1994-06-22 Application filed by Univ Michigan, Knoll Ag filed Critical Univ Michigan

2003-04-07 Application granted granted Critical

2003-04-07 Publication of DK0751769T3 publication Critical patent/DK0751769T3/da

Links

239000005495 thyroid hormone Substances 0.000 title abstract 2
229940036555 thyroid hormone Drugs 0.000 title abstract 2
AUYYCJSJGJYCDS-LBPRGKRZSA-N Thyrolar Chemical class IC1=CC(C[C@H](N)C(O)=O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 AUYYCJSJGJYCDS-LBPRGKRZSA-N 0.000 abstract 2
ZHSOTLOTTDYIIK-ZDUSSCGKSA-N (2S)-2-amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid Chemical compound IC1=CC(C[C@H](N)C(O)=O)=CC(I)=C1OC1=CC=C(O)C=C1 ZHSOTLOTTDYIIK-ZDUSSCGKSA-N 0.000 abstract 1
HZCBWYNLGPIQRK-LBPRGKRZSA-N 3,3',5'-triiodo-L-thyronine Chemical compound IC1=CC(C[C@H]([NH3+])C([O-])=O)=CC=C1OC1=CC(I)=C(O)C(I)=C1 HZCBWYNLGPIQRK-LBPRGKRZSA-N 0.000 abstract 1
201000006474 Brain Ischemia Diseases 0.000 abstract 1
206010008120 Cerebral ischaemia Diseases 0.000 abstract 1
208000010496 Heart Arrest Diseases 0.000 abstract 1
XUIIKFGFIJCVMT-LBPRGKRZSA-N L-thyroxine Chemical compound IC1=CC(C[C@H]([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-LBPRGKRZSA-N 0.000 abstract 1
230000001154 acute effect Effects 0.000 abstract 1
210000003169 central nervous system Anatomy 0.000 abstract 1
206010008118 cerebral infarction Diseases 0.000 abstract 1
208000028867 ischemia Diseases 0.000 abstract 1
229950008325 levothyroxine Drugs 0.000 abstract 1
159000000000 sodium salts Chemical class 0.000 abstract 1
XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 abstract 1
229940035722 triiodothyronine Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK94921305T 1993-06-22 1994-06-22 Medicinsk behandling under anvendelse af skjoldbruskhormoner DK0751769T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7980593A	1993-06-22	1993-06-22
PCT/US1994/006772 WO1995000135A1 (en)	1993-06-22	1994-06-22	Medical treatment using thyroid hormones

Publications (1)

Publication Number	Publication Date
DK0751769T3 true DK0751769T3 (da)	2003-04-07

Family

ID=22152935

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94921305T DK0751769T3 (da)	1993-06-22	1994-06-22	Medicinsk behandling under anvendelse af skjoldbruskhormoner

Country Status (11)

Country	Link
US (1)	US5571840A (de)
EP (1)	EP0751769B1 (de)
JP (1)	JPH09503485A (de)
KR (1)	KR100348117B1 (de)
AT (1)	ATE230986T1 (de)
AU (1)	AU680669B2 (de)
CA (1)	CA2165822A1 (de)
DE (1)	DE69432027T2 (de)
DK (1)	DK0751769T3 (de)
ES (1)	ES2192194T3 (de)
WO (1)	WO1995000135A1 (de)

Families Citing this family (54)

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GB9401891D0 (en) *	1994-02-01	1994-03-30	Boots Co Plc	Therapeutic agents
EP1156940A4 (de)	1999-02-10	2006-02-08	Erik Zapletal	Ausgeglichenes aufhängungssystem
US6500834B1 (en)	1999-04-27	2002-12-31	Board Of Regents, The University Of Texas System	Composition and method for treatment of cerebral ischemia
EP1223931B1 (de) *	1999-10-29	2005-12-14	Orion Corporation	Verwendung eines imidazolderivats zur behandlung oder verhütung von hypotension und schock
US7235649B2 (en) *	2000-03-24	2007-06-26	Duke University	Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, and screening methods employing same
CA2429196A1 (en) *	2000-03-24	2001-10-04	Duke University	Characterization of grp94-ligand interactions and purification, screening, and therapeutic methods relating thereto
US20020193440A1 (en) *	2001-02-20	2002-12-19	Ritter Steven C.	Liothyronine sodium and levothyroxine sodium combination
US6645526B2 (en) *	2001-11-13	2003-11-11	Mylan Pharmaceuticals, Inc.	Storage stable thyroxine active drug formulations and methods for their production
US20030099699A1 (en)	2001-11-13	2003-05-29	Hanshew Dwight D.	Storage stable thyroxine active drug formulations and methods for their production
US20040156893A1 (en) *	2003-02-11	2004-08-12	Irwin Klein	Method for treating hypothyroidism
ITRM20030363A1 (it) *	2003-07-24	2005-01-25	Fernando Goglia	Composizioni comprendenti la 3, 5diiodotironina e uso farmaceutico di esse.
US8668926B1 (en)	2003-09-15	2014-03-11	Shaker A. Mousa	Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof
CA2539288C (en) *	2003-09-15	2015-05-12	Shaker A. Mousa	Thyroid hormone analogs and methods of use
US8071134B2 (en)	2003-09-15	2011-12-06	Ordway Research Institute, Inc.	Thyroid hormone analogs and methods of use
US9198887B2 (en)	2003-09-15	2015-12-01	Nanopharmaceuticals Llc	Thyroid hormone analogs and methods of use
CN1882327A (zh) *	2003-11-19	2006-12-20	症变治疗公司	含磷的新的拟甲状腺素药
CN101102758B (zh) *	2004-09-15	2011-11-16	奥德威研究院	促进血管新生的甲状腺激素类似物
US20060128797A1 (en) *	2004-12-15	2006-06-15	Yanming Wang	Method and composition for resuscitation
AU2006230557A1 (en) *	2005-03-31	2006-10-05	King Pharmaceuticals Research & Development, Inc.	Controlled release pharmaceutical compositions of liothyronine and methods of making and using the same
WO2006128056A2 (en) *	2005-05-26	2006-11-30	Metabasis Therapeutics, Inc.	Novel phosphinic acid-containing thyromimetics
MX2007014502A (es)	2005-05-26	2008-02-07	Metabasis Therapeutics Inc	Tiromimeticos para el tratamiento de enfermedades del higado graso.
US9220788B2 (en)	2009-06-17	2015-12-29	Nanopharmaceuticals Llc	Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof
US10130686B2 (en)	2005-09-15	2018-11-20	Nanopharmaceuticals Llc	Method and composition of thyroid hormone analogues and nanoformulations thereof for treating inflammatory disorders
US9498536B2 (en)	2005-09-15	2016-11-22	Nanopharmaceuticals Llc	Method and composition of thyroid hormone analogues and nanoformulations thereof for treating anti-inflammatory disorders
WO2007035612A2 (en)	2005-09-16	2007-03-29	Ordway Research Institute, Inc.	Polyphenol conjugates as rgd-binding compounds and methods of use
EP2120913B1 (de)	2006-12-22	2015-01-21	NanoPharmaceuticals LLC	Nanopartikel- und polymerformulierungen für schilddrüsenhormonanaloga, -antagonisten und -formulierungen sowie verwendungen damit
US9180107B2 (en)	2009-03-31	2015-11-10	Nanopharmaceuticals Llc	Combination treatment of cancer with cetuximab and tetrac
SG175979A1 (en) *	2009-05-15	2011-12-29	Recro Pharma Inc	Sublingual dexmedetomidine compositions and methods of use thereof
US8802240B2 (en)	2011-01-06	2014-08-12	Nanopharmaceuticals Llc	Uses of formulations of thyroid hormone analogs and nanoparticulate forms thereof to increase chemosensitivity and radiosensitivity in tumor or cancer cells
WO2013090278A2 (en)	2011-12-11	2013-06-20	Recro Pharma, Inc.	Intranasal dexmedetomidine compositions and methods of use thereof
US10060934B2 (en)	2013-11-18	2018-08-28	Nanopharmaceuticals Llc	Methods for screening patients for resistance to angioinhibition, treatment and prophylaxis thereof
KR101848231B1 (ko) *	2015-06-29	2018-05-29	한양대학교 산학협력단	트리요오드티로닌, 티록신 또는 이의 염을 포함하는 뇌신경계 질환의 예방, 개선 또는 치료용 조성물
US10201616B2 (en)	2016-06-07	2019-02-12	Nanopharmaceuticals, Llc	Non-cleavable polymer conjugated with αVβ3 integrin thyroid antagonists
JP2020500199A (ja)	2016-11-21	2020-01-09	バイキング・セラピューティクス・インコーポレイテッド	グリコーゲン蓄積症の治療方法
AU2018280118B2 (en)	2017-06-05	2021-07-15	Viking Therapeutics, Inc.	Compositions for the treatment of fibrosis
EP4732889A2 (de)	2017-06-07	2026-04-29	Supira Medical, Inc.	Vorrichtungen, systeme und verfahren zur bewegung intravaskulärer flüssigkeiten
US11511103B2 (en)	2017-11-13	2022-11-29	Shifamed Holdings, Llc	Intravascular fluid movement devices, systems, and methods of use
JP7410034B2 (ja)	2018-02-01	2024-01-09	シファメド・ホールディングス・エルエルシー	血管内血液ポンプならびに使用および製造の方法
ES3053674T3 (en)	2018-03-22	2026-01-23	Viking Therapeutics Inc	Crystalline forms and methods of producing crystalline forms of a compound
US11351137B2 (en)	2018-04-11	2022-06-07	Nanopharmaceuticals Llc	Composition and method for dual targeting in treatment of neuroendocrine tumors
US10328043B1 (en)	2018-04-11	2019-06-25	Nanopharmaceuticals, Llc.	Composition and method for dual targeting in treatment of neuroendocrine tumors
WO2020028537A1 (en)	2018-07-31	2020-02-06	Shifamed Holdings, Llc	Intravascaular blood pumps and methods of use
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WO2020117962A1 (en)	2018-12-05	2020-06-11	Viking Therapeutics, Inc.	Compositions for the treatment of fibrosis and inflammation
SI3908272T1 (sl) *	2019-01-09	2023-07-31	Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.	L-trijodotironin (t3) za uporabo pri omejevanju mikrovaskularne obstrukcije
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US11654275B2 (en)	2019-07-22	2023-05-23	Shifamed Holdings, Llc	Intravascular blood pumps with struts and methods of use and manufacture
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US12599758B2 (en)	2019-12-19	2026-04-14	Shifamed Holdings, Llc	Intravascular blood pumps, motors, and fluid control
GR1010068B (el) *	2020-04-21	2021-09-01	UNI-PHARMA ΚΛΕΩΝ ΤΣΕΤΗΣ ΦΑΡΜΑΚΕΥΤΙΚΑ ΕΡΓΑΣΤΗΡΙΑ ΑΒΕΕ με δ.τ. "UNI-PHARMA ABEE"	Φαρμακευτικη συνθεση που περιεχει l-τριιωδοθυρονινη (τ3) για χρηση στη θεραπεια ασθενων σε κρισιμη κατασταση με λοιμωξη απο κορωνοϊο
US10961204B1 (en)	2020-04-29	2021-03-30	Nanopharmaceuticals Llc	Composition of scalable thyrointegrin antagonists with improved blood brain barrier penetration and retention into brain tumors
US11723888B2 (en)	2021-12-09	2023-08-15	Nanopharmaceuticals Llc	Polymer conjugated thyrointegrin antagonists

Family Cites Families (3)

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IT1237435B (it) *	1989-12-14	1993-06-04		Farmaco attivo nel ripristino della plasticita' neuronale.
US5158978A (en) *	1990-02-05	1992-10-27	British Technology Group (U.S.A.)	Thyroid hormone treatment of acute cardiovascular compromise
EP0466909B1 (de) *	1990-02-05	1995-06-28	British Technology Group (Usa) Incorporated	Schilddrüsenhormone zur kardialen behandlung

1994
- 1994-06-06 US US08/254,417 patent/US5571840A/en not_active Expired - Fee Related
- 1994-06-22 KR KR1019950705857A patent/KR100348117B1/ko not_active Expired - Fee Related
- 1994-06-22 WO PCT/US1994/006772 patent/WO1995000135A1/en not_active Ceased
- 1994-06-22 JP JP7502930A patent/JPH09503485A/ja not_active Ceased
- 1994-06-22 CA CA002165822A patent/CA2165822A1/en not_active Abandoned
- 1994-06-22 AU AU72080/94A patent/AU680669B2/en not_active Ceased
- 1994-06-22 AT AT94921305T patent/ATE230986T1/de not_active IP Right Cessation
- 1994-06-22 DK DK94921305T patent/DK0751769T3/da active
- 1994-06-22 ES ES94921305T patent/ES2192194T3/es not_active Expired - Lifetime
- 1994-06-22 EP EP94921305A patent/EP0751769B1/de not_active Expired - Lifetime
- 1994-06-22 DE DE69432027T patent/DE69432027T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JPH09503485A (ja)	1997-04-08
US5571840A (en)	1996-11-05
DE69432027T2 (de)	2003-10-09
KR100348117B1 (ko)	2002-12-02
AU680669B2 (en)	1997-08-07
AU7208094A (en)	1995-01-17
EP0751769A1 (de)	1997-01-08
WO1995000135A1 (en)	1995-01-05
EP0751769B1 (de)	2003-01-15
ES2192194T3 (es)	2003-10-01
CA2165822A1 (en)	1995-01-05
DE69432027D1 (de)	2003-02-20
ATE230986T1 (de)	2003-02-15
EP0751769A4 (de)	1998-05-27

Publication	Publication Date	Title
DK0751769T3 (da)	2003-04-07	Medicinsk behandling under anvendelse af skjoldbruskhormoner
EP0802782A4 (de)	1998-04-01	Prophylaktische und therapeutische behandlung von haupt sensibilisierung und -reizung
DK0550108T3 (da)	1999-01-04	Thyreoaktiv sammensætning med langvarig frigivelse
PT741577E (pt)	2003-03-31	Utilizacao do subtipo de interferao alfa 8 na preparacao de medicamentos para tratar infeccoes virais do figado
DK0814796T3 (da)	2005-09-19	Anvendelse af et R-NSAID i en protektiv sammensætning til behandling af kolorektal cancer
DK581685A (da)	1986-06-18	Transderimalt system for timolol-indgift
DE3752112D1 (de)	1997-10-02	Verwendung von Inositoltriphosphat zur Behandlung von Entzündungen
ATE78169T1 (de)	1992-08-15	Behandlung von diabetes durch kombinierte insulinformen.
YU75093A (sh)	1997-08-22	Transdermalni sistem za davanje koji sadrži acetilsalicilnu kiselinu za antitromboznu terapiju i profilaksu raka
NO305581B1 (no)	1999-06-28	Anvendelse av et benaktivt fosfonat i kombinasjon med et °strogenhormon, og preparat i enhetsdoseform for behandling av osteoporose
SE7612534L (sv)	1977-06-02	Forfarande for framstellning av farmaceutiska preparat for behandling av storningar i kalciumemnesomsettning
MA22915A1 (fr)	1993-12-31	Methodes de traitement de l'osteoporose pour utilisation de faibles doses de phosphonates.
MY104521A (en)	1994-04-30	Treatment of depression.
DK0590355T3 (da)	1998-03-02	Anvendelse af L-carnitin og acyl-L-carnitiner til behandling af patienter, der lider af AIDS-relaterede syndromer og asymptomatiske HIV-seropositive patienter
DE69028971D1 (de)	1996-11-28	Hypertensiver faktor des parathyroids
DE3275060D1 (en)	1987-02-19	Use of beta-(1-adamantyl)-alpha, alpha-dimethylethylamine for the manufacture of a medicament for the treatment of otitis externa in dogs
GB9106278D0 (en)	1991-05-08	Method of treatment
RU97101420A (ru)	1998-09-10	Способ лечения тонзиллита
TR199701604T2 (xx)	2000-10-23	Pirol t�revleri i�in yeni ba�vuru
ATE87482T1 (de)	1993-04-15	Pharmazeutische praeparate zur behandlung von zereberalen psycho-organischen syndromen.
ATE8966T1 (de)	1984-09-15	Analgetische potenzierung.
DE3365954D1 (en)	1986-10-16	The use of alpha, alpha-dialkyl adamanthylethylamines to treat measles
ES8500055A1 (es)	1984-10-01	Procedimiento para la obtencion de un medicamento a base de un derivado de pirazolinona.
IL107818A0 (en)	1994-04-12	Method of treating viral infections by conjunctive therapy with acyclovir-like compounds and a 2'-vinyl substituted nucleoside analog
SG49645A1 (en)	1999-10-19	A method of treating liver disease and like indications with vasodilating agents