DK0754181T3 - Fremgangsmåde til fremstilling af 7-hydroxytaxaner - Google Patents

Fremgangsmåde til fremstilling af 7-hydroxytaxaner

Info

Publication number: DK0754181T3
Authority: DK; Denmark
Prior art keywords: radical; pct; general formula; optionally substituted; image
Prior art date: 1994-04-05

Application number

DK95916697T

Other languages

Danish (da)

English (en)

Inventor

Alain Commercon

Jean-Dominique Bourzat

Jean-Pierre Bastart

Jean-Pierre Leconte

Original Assignee

Rhone Poulenc Rorer Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-05

Filing date

1995-04-03

Publication date

1998-11-16

1995-04-03 Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa

1998-11-16 Application granted granted Critical

1998-11-16 Publication of DK0754181T3 publication Critical patent/DK0754181T3/da

Links

229940123237 Taxane Drugs 0.000 title abstract 3
-1 heterocyclyl radical Chemical class 0.000 abstract 4
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000003342 alkenyl group Chemical group 0.000 abstract 2
125000000304 alkynyl group Chemical group 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical class [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001602 bicycloalkyls Chemical group 0.000 abstract 1
125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
125000006239 protecting group Chemical group 0.000 abstract 1
150000003254 radicals Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK95916697T 1994-04-05 1995-04-03 Fremgangsmåde til fremstilling af 7-hydroxytaxaner DK0754181T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9403980A FR2718135B1 (fr)	1994-04-05	1994-04-05	Procédé de préparation d'hydroxy-7 taxanes.
PCT/FR1995/000420 WO1995026961A1 (fr)	1994-04-05	1995-04-03	Procede de preparation d'hydroxy-7 taxanes

Publications (1)

Publication Number	Publication Date
DK0754181T3 true DK0754181T3 (da)	1998-11-16

Family

ID=9461748

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95916697T DK0754181T3 (da)	1994-04-05	1995-04-03	Fremgangsmåde til fremstilling af 7-hydroxytaxaner

Country Status (31)

Country	Link
US (1)	US5750738A (de)
EP (1)	EP0754181B1 (de)
JP (1)	JPH09511245A (de)
KR (1)	KR970702269A (de)
CN (1)	CN1066144C (de)
AT (1)	ATE168109T1 (de)
AU (1)	AU691916B2 (de)
BG (1)	BG62731B1 (de)
BR (1)	BR9507443A (de)
CA (1)	CA2186917A1 (de)
CZ (1)	CZ284725B6 (de)
DE (1)	DE69503366T2 (de)
DK (1)	DK0754181T3 (de)
EE (1)	EE03239B1 (de)
ES (1)	ES2118592T3 (de)
FI (1)	FI964002A7 (de)
FR (1)	FR2718135B1 (de)
GE (1)	GEP19991535B (de)
HU (1)	HU214157B (de)
LT (1)	LT4186B (de)
LV (1)	LV11685B (de)
NO (1)	NO314145B1 (de)
NZ (1)	NZ284491A (de)
PL (1)	PL316589A1 (de)
RO (1)	RO115727B1 (de)
RU (1)	RU2127730C1 (de)
SK (1)	SK281075B6 (de)
TW (1)	TW285669B (de)
UA (1)	UA45332C2 (de)
WO (1)	WO1995026961A1 (de)
ZA (1)	ZA952732B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2732968B1 (fr) *	1995-04-14	1997-05-16	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2750989B1 (fr) *	1996-07-09	1998-09-25	Rhone Poulenc Rorer Sa	Procede de monoacylation d'hydroxy taxanes
ATE256117T1 (de) *	1999-05-17	2003-12-15	Bristol Myers Squibb Co	Neue umsetzungsbedingungen für die spaltung von silylethern bei der herstellung von paclitaxel (taxol(r)) und paclitaxel -analogen
JP4776843B2 (ja)	1999-10-01	2011-09-21	イムノゲンインコーポレーティッド	免疫複合体及び化学療法剤を用いる癌治療用組成物及び方法
KR101806323B1 (ko)	2009-11-13	2017-12-07	다이이치 산쿄 유럽 게엠베하	Ｈｅｒ-３ 관련 질병을 치료하거나 예방하기 위한 물질 및 방법
AU2011286407A1 (en)	2010-08-06	2013-02-21	Amgen	Use of HER3 binding agents in prostate treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2629818B1 (fr) *	1988-04-06	1990-11-16	Centre Nat Rech Scient	Procede de preparation du taxol
FR2678930B1 (fr) *	1991-07-10	1995-01-13	Rhone Poulenc Rorer Sa	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.

1994
- 1994-04-05 FR FR9403980A patent/FR2718135B1/fr not_active Expired - Fee Related
1995
- 1995-03-22 TW TW084102786A patent/TW285669B/zh active
- 1995-04-03 US US08/722,106 patent/US5750738A/en not_active Expired - Fee Related
- 1995-04-03 UA UA96093733A patent/UA45332C2/uk unknown
- 1995-04-03 EE EE9600141A patent/EE03239B1/xx not_active IP Right Cessation
- 1995-04-03 DK DK95916697T patent/DK0754181T3/da active
- 1995-04-03 PL PL95316589A patent/PL316589A1/xx unknown
- 1995-04-03 WO PCT/FR1995/000420 patent/WO1995026961A1/fr not_active Ceased
- 1995-04-03 AT AT95916697T patent/ATE168109T1/de not_active IP Right Cessation
- 1995-04-03 KR KR1019960705643A patent/KR970702269A/ko not_active Abandoned
- 1995-04-03 GE GEAP19953432A patent/GEP19991535B/en unknown
- 1995-04-03 JP JP7525467A patent/JPH09511245A/ja not_active Ceased
- 1995-04-03 SK SK1264-96A patent/SK281075B6/sk unknown
- 1995-04-03 ZA ZA952732A patent/ZA952732B/xx unknown
- 1995-04-03 CZ CZ962899A patent/CZ284725B6/cs not_active IP Right Cessation
- 1995-04-03 AU AU23097/95A patent/AU691916B2/en not_active Ceased
- 1995-04-03 RU RU96120193A patent/RU2127730C1/ru active
- 1995-04-03 NZ NZ284491A patent/NZ284491A/en unknown
- 1995-04-03 DE DE69503366T patent/DE69503366T2/de not_active Expired - Fee Related
- 1995-04-03 CA CA002186917A patent/CA2186917A1/fr not_active Abandoned
- 1995-04-03 RO RO96-01922A patent/RO115727B1/ro unknown
- 1995-04-03 BR BR9507443A patent/BR9507443A/pt not_active IP Right Cessation
- 1995-04-03 EP EP95916697A patent/EP0754181B1/de not_active Expired - Lifetime
- 1995-04-03 CN CN95192428A patent/CN1066144C/zh not_active Expired - Fee Related
- 1995-04-03 ES ES95916697T patent/ES2118592T3/es not_active Expired - Lifetime
- 1995-04-03 HU HU9602736A patent/HU214157B/hu not_active IP Right Cessation
1996
- 1996-09-24 LT LT96-138A patent/LT4186B/lt not_active IP Right Cessation
- 1996-09-27 NO NO19964104A patent/NO314145B1/no not_active IP Right Cessation
- 1996-10-04 FI FI964002A patent/FI964002A7/fi unknown
- 1996-10-04 BG BG100887A patent/BG62731B1/bg unknown
- 1996-10-07 LV LVP-96-393A patent/LV11685B/lv unknown

Also Published As

Publication number	Publication date
EP0754181B1 (de)	1998-07-08
NO314145B1 (no)	2003-02-03
HU214157B (hu)	1998-01-28
ES2118592T3 (es)	1998-09-16
CZ284725B6 (cs)	1999-02-17
HUT75690A (en)	1997-05-28
TW285669B (de)	1996-09-11
DE69503366T2 (de)	1999-01-21
CA2186917A1 (fr)	1995-10-12
FI964002A0 (fi)	1996-10-04
KR970702269A (ko)	1997-05-13
CN1066144C (zh)	2001-05-23
FI964002A7 (fi)	1996-10-04
US5750738A (en)	1998-05-12
AU691916B2 (en)	1998-05-28
RO115727B1 (ro)	2000-05-30
BR9507443A (pt)	1997-09-16
LT96138A (en)	1997-02-25
WO1995026961A1 (fr)	1995-10-12
FR2718135B1 (fr)	1996-04-26
LV11685B (en)	1997-06-20
BG62731B1 (bg)	2000-06-30
CZ289996A3 (en)	1997-01-15
LV11685A (lv)	1997-02-20
JPH09511245A (ja)	1997-11-11
AU2309795A (en)	1995-10-23
SK126496A3 (en)	1997-05-07
EP0754181A1 (de)	1997-01-22
ATE168109T1 (de)	1998-07-15
HU9602736D0 (en)	1996-11-28
RU2127730C1 (ru)	1999-03-20
DE69503366D1 (de)	1998-08-13
FR2718135A1 (fr)	1995-10-06
NO964104D0 (no)	1996-09-27
NO964104L (no)	1996-09-27
PL316589A1 (en)	1997-01-20
UA45332C2 (uk)	2002-04-15
MX9604465A (es)	1997-07-31
NZ284491A (en)	1998-01-26
SK281075B6 (sk)	2000-11-07
BG100887A (en)	1998-01-30
ZA952732B (en)	1996-01-09
CN1145070A (zh)	1997-03-12
GEP19991535B (en)	1999-03-05
LT4186B (en)	1997-07-25
EE03239B1 (et)	1999-12-15

Publication	Publication Date	Title
DK0663905T3 (da)	1997-02-03	Ny fremgangsmåde dtil forestring af baccatin III og 10-desacetylbaccatin III
DK0687259T3 (da)	1997-05-26	Fremgangsmåde til fremstilling af taxoider
DE60229054D1 (de)	2008-11-06	Synthese von zyklopentadien derivaten
DK0754185T3 (da)	1998-01-26	Fremgangmåde til fremstilling af 7-trialkylsilyl-baccatin III
NO964104L (no)	1996-09-27	Fremgangsmåte for fremstilling av 7-hydroksy-taxaner
NO971765D0 (no)	1997-04-17	Nye taxoider, deres fremstilling og farmasöytiske preparater inneholdende forbindelsene
DE59807744D1 (de)	2003-05-08	Verwendung von sulfonyloxadiazolonen als mikrobizide
DK0669915T3 (da)	1997-08-18	Fremgangsmåde til fremstilling af en 1,3-oxazolidin-5-carboxylsyre
DK0649426T3 (da)	2002-01-21	Inhibitorer af retrovirale proteaser