DK0762877T3 - Meta-substituerede arylalkylaminer og terapeutiske og diagnostiske anvendelser deraf - Google Patents
Meta-substituerede arylalkylaminer og terapeutiske og diagnostiske anvendelser derafInfo
- Publication number
- DK0762877T3 DK0762877T3 DK95922166T DK95922166T DK0762877T3 DK 0762877 T3 DK0762877 T3 DK 0762877T3 DK 95922166 T DK95922166 T DK 95922166T DK 95922166 T DK95922166 T DK 95922166T DK 0762877 T3 DK0762877 T3 DK 0762877T3
- Authority
- DK
- Denmark
- Prior art keywords
- meta
- therapeutic
- diagnostic uses
- substituted arylalkylamines
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/30—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25403294A | 1994-06-06 | 1994-06-06 | |
| US08/265,512 US6004990A (en) | 1994-06-03 | 1994-06-24 | Meta substituted arylalkylamines and therapeutic and diagnostic uses therefor |
| PCT/US1995/006950 WO1995033455A1 (en) | 1994-06-03 | 1995-06-02 | Meta substituted arylalkylamines and therapeutic and diagnostic uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0762877T3 true DK0762877T3 (da) | 2001-07-16 |
Family
ID=26943786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95922166T DK0762877T3 (da) | 1994-06-03 | 1995-06-02 | Meta-substituerede arylalkylaminer og terapeutiske og diagnostiske anvendelser deraf |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5587398A (de) |
| EP (1) | EP0762877B1 (de) |
| JP (1) | JP3839049B2 (de) |
| AT (1) | ATE199829T1 (de) |
| AU (1) | AU707142B2 (de) |
| CA (1) | CA2191996A1 (de) |
| DE (1) | DE69520430T2 (de) |
| DK (1) | DK0762877T3 (de) |
| ES (1) | ES2157330T3 (de) |
| GR (1) | GR3036072T3 (de) |
| PT (1) | PT762877E (de) |
| WO (1) | WO1995033455A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4426245A1 (de) | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
| PT1064256E (pt) * | 1998-03-17 | 2004-10-29 | Pfizer Prod Inc | Biciclo[2.2.1] heptanos e compostos relacionados |
| US6245782B1 (en) | 1999-05-17 | 2001-06-12 | Heartdrug Research L.L.C. | Methods of inhibiting platelet activation with selective serotonin reuptake inhibitors |
| US20040018959A1 (en) * | 2002-05-02 | 2004-01-29 | Randall S. Hickle | System and methods of lipid removal from the body |
| AU2009205539B2 (en) * | 2008-01-18 | 2013-12-05 | Allergan.Inc | Substitued-aryl-(imidazole)-methyl)-phenyl compounds as subtype selective modulators of alpha 2B and/or alpha 2C adrenergic receptors |
| US9549909B2 (en) | 2013-05-03 | 2017-01-24 | The Katholieke Universiteit Leuven | Method for the treatment of dravet syndrome |
| CN107111673B (zh) | 2014-09-29 | 2021-03-23 | 周格尼克斯国际有限公司 | 控制药物分配的控制系统 |
| EP3170807B1 (de) | 2015-11-23 | 2019-12-11 | Frau Pharma S.r.l. | Neues verfahren zur synthese von fenfluramin |
| ES3024232T3 (en) | 2015-12-22 | 2025-06-04 | Zogenix International Ltd | Fenfluramine compositions and methods of preparing the same |
| WO2017112701A1 (en) * | 2015-12-22 | 2017-06-29 | Zogenix International Limited | Metabolism resistant fenfluramine analogs and methods of using the same |
| SG11201900975XA (en) | 2016-08-24 | 2019-03-28 | Zogenix International Ltd | Formulation for inhibiting formation of 5-ht 2b agonists and methods of using same |
| US10682317B2 (en) | 2017-09-26 | 2020-06-16 | Zogenix International Limited | Ketogenic diet compatible fenfluramine formulation |
| WO2019216919A1 (en) | 2018-05-11 | 2019-11-14 | Zogenix International Limited | Compositions and methods for treating seizure-induced sudden death |
| JP2021530541A (ja) * | 2018-07-27 | 2021-11-11 | ゼノン・ファーマシューティカルズ・インコーポレイテッドXenon Pharmaceuticals Inc. | てんかんの治療方法 |
| EA202191079A1 (ru) | 2018-11-19 | 2021-09-20 | Зодженикс Интернэшнл Лимитед | Способы лечения синдрома ретта с применением фенфлурамина |
| US11612574B2 (en) | 2020-07-17 | 2023-03-28 | Zogenix International Limited | Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR6626M (de) * | 1967-09-22 | 1969-01-13 | ||
| DE1802297C3 (de) * | 1967-10-25 | 1974-10-17 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt, Budapest | Isopropylaminderivate und Verfahren zu ihrer Herstellung |
| US3573304A (en) * | 1968-12-03 | 1971-03-30 | Delalande Sa | 1-dimethylamino - 3 - methyl-2(pyridyl or pyridazinyl) pentane and the corresponding non-toxic acid addition salts thereof |
| US3856857A (en) * | 1970-02-13 | 1974-12-24 | En Nom Collectif Science Union | Amino acids and their derivatives |
| US3733339A (en) * | 1970-10-05 | 1973-05-15 | Abbott Lab | Disubstituted propionamides |
| USB787097I5 (de) * | 1971-06-04 | |||
| BE791772A (fr) * | 1971-06-11 | 1973-03-16 | Buzas Andre | Derives d'acides phenoxy-acetiques, leur preparation et leur application en therapeutique |
| BE795041A (fr) * | 1972-02-07 | 1973-08-06 | Science Union & Cie | Nouveaux derives de l'amino-propane |
| GB1434088A (en) * | 1973-08-16 | 1976-04-28 | Science Union & Cie | N-substituted glycinates a process for their preparation and pharmaceutical compositions containing them |
| US4025624A (en) * | 1975-11-18 | 1977-05-24 | A. H. Robins Company, Incorporated | Phenylalkylamines and phenylalkylureas in combinations to suppress gastric bleeding in aspirin therapy |
| US4115587A (en) * | 1976-02-04 | 1978-09-19 | A. H. Robins Company, Inc. | Fatty acid amides of norfenfluramine and compositions and methods thereof |
| US4237165A (en) * | 1976-06-04 | 1980-12-02 | Science Union Et Cie | Treatment of carbohydrate metabolism disorders |
| FR2508442A1 (fr) * | 1981-06-30 | 1982-12-31 | Sanofi Sa | Procede de preparation d'ethylamines b-cyclo-substituees et produits ainsi obtenus |
| HU207282B (en) * | 1984-05-31 | 1993-03-29 | Chinoin Gyogyszer Es Vegyeszet | Process for producing phenyl-alkyl-amine derivatives and pharmaceutical compositions containing them |
| HU197510B (en) * | 1986-12-19 | 1989-04-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing pharmaceutical composition containing phenyl-alkyl-amine derivatives, against motion-sick |
| US4857553A (en) * | 1987-08-06 | 1989-08-15 | A. H. Robins Company, Incorporated | Method of treating nausea and vomiting with certain substituted-phenylalkylamino (and aminoacid) derivatives and other serotonin depleting agents |
| JP2938463B2 (ja) * | 1987-10-22 | 1999-08-23 | マサチユセツツ・インスチチユート・オブ・テクノロジー | 月経前又は後期黄体期症候群の処置 |
| GB8807504D0 (en) * | 1988-03-29 | 1988-05-05 | Sandoz Ltd | Improvements in/relating to organic compounds |
| US4999382A (en) * | 1988-10-26 | 1991-03-12 | Massachusetts Institute Of Technology | Compositions for treating tobacco withdrawal symptoms and methods for their use |
| GB9011767D0 (en) * | 1990-05-25 | 1990-07-18 | Britannia Pharmaceuticals Ltd | Pharmaceutical compositions |
-
1995
- 1995-06-02 EP EP95922166A patent/EP0762877B1/de not_active Expired - Lifetime
- 1995-06-02 DK DK95922166T patent/DK0762877T3/da active
- 1995-06-02 AT AT95922166T patent/ATE199829T1/de not_active IP Right Cessation
- 1995-06-02 ES ES95922166T patent/ES2157330T3/es not_active Expired - Lifetime
- 1995-06-02 WO PCT/US1995/006950 patent/WO1995033455A1/en not_active Ceased
- 1995-06-02 PT PT95922166T patent/PT762877E/pt unknown
- 1995-06-02 AU AU26950/95A patent/AU707142B2/en not_active Ceased
- 1995-06-02 DE DE69520430T patent/DE69520430T2/de not_active Expired - Fee Related
- 1995-06-02 JP JP50119996A patent/JP3839049B2/ja not_active Expired - Fee Related
- 1995-06-02 US US08/461,577 patent/US5587398A/en not_active Expired - Lifetime
- 1995-06-02 CA CA002191996A patent/CA2191996A1/en not_active Abandoned
-
1999
- 1999-08-13 US US09/374,170 patent/US6313175B1/en not_active Expired - Fee Related
-
2001
- 2001-06-19 GR GR20010400916T patent/GR3036072T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US5587398A (en) | 1996-12-24 |
| US6313175B1 (en) | 2001-11-06 |
| EP0762877A1 (de) | 1997-03-19 |
| JP3839049B2 (ja) | 2006-11-01 |
| AU707142B2 (en) | 1999-07-01 |
| GR3036072T3 (en) | 2001-09-28 |
| DE69520430D1 (de) | 2001-04-26 |
| DE69520430T2 (de) | 2001-10-18 |
| PT762877E (pt) | 2001-08-30 |
| CA2191996A1 (en) | 1995-12-14 |
| ES2157330T3 (es) | 2001-08-16 |
| JPH10501239A (ja) | 1998-02-03 |
| WO1995033455A1 (en) | 1995-12-14 |
| AU2695095A (en) | 1996-01-04 |
| EP0762877B1 (de) | 2001-03-21 |
| HK1014671A1 (en) | 1999-09-30 |
| ATE199829T1 (de) | 2001-04-15 |
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