DK0765321T3 - 2-amino-3-aroylbenzo-beta-thiophener og fremgangsmåde til fremstilling deraf - Google Patents

2-amino-3-aroylbenzo-beta-thiophener og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0765321T3
DK0765321T3 DK95922292T DK95922292T DK0765321T3 DK 0765321 T3 DK0765321 T3 DK 0765321T3 DK 95922292 T DK95922292 T DK 95922292T DK 95922292 T DK95922292 T DK 95922292T DK 0765321 T3 DK0765321 T3 DK 0765321T3
Authority
DK
Denmark
Prior art keywords
beta
amino
thiophenes
benzo
aroylbenzo
Prior art date
Application number
DK95922292T
Other languages
Danish (da)
English (en)
Inventor
Alexander Glenn Godfrey
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0765321T3 publication Critical patent/DK0765321T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/66—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Child & Adolescent Psychology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Thermal Insulation (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Cephalosporin Compounds (AREA)
DK95922292T 1994-06-10 1995-06-07 2-amino-3-aroylbenzo-beta-thiophener og fremgangsmåde til fremstilling deraf DK0765321T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/257,859 US5466810A (en) 1994-06-10 1994-06-10 2-amino-3-aroyl-benzo[β]thiophenes and methods for preparing and using same to produce 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-aminoethoxy)-benzoyl]benzo[β]thiophenes
PCT/US1995/007397 WO1995034557A1 (fr) 1994-06-10 1995-06-07 2-AMINO-3-AROYL-BENZO[β]THIOPHENES ET PROCEDE DE PRODUCTION DE CES COMPOSES

Publications (1)

Publication Number Publication Date
DK0765321T3 true DK0765321T3 (da) 2001-05-07

Family

ID=22978079

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95922292T DK0765321T3 (da) 1994-06-10 1995-06-07 2-amino-3-aroylbenzo-beta-thiophener og fremgangsmåde til fremstilling deraf

Country Status (14)

Country Link
US (3) US5466810A (fr)
EP (1) EP0765321B1 (fr)
JP (1) JPH10502057A (fr)
AT (1) ATE200671T1 (fr)
AU (1) AU2702995A (fr)
BR (1) BR9507956A (fr)
CA (1) CA2192097A1 (fr)
DE (1) DE69520738T2 (fr)
DK (1) DK0765321T3 (fr)
ES (1) ES2155891T3 (fr)
FI (1) FI964914L (fr)
GR (1) GR3036028T3 (fr)
PT (1) PT765321E (fr)
WO (1) WO1995034557A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US5770609A (en) 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5595722A (en) 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
WO1996040098A2 (fr) 1995-06-07 1996-12-19 Neorx Corporation Prevention et traitement de pathologies cardio-vasculaires au moyen d'analogues de tamoxifene
US5606075A (en) * 1995-06-07 1997-02-25 Eli Lilly And Company Process for the synthesis of benzo[b]thiophenes
CA2207141A1 (fr) * 1996-07-15 1998-01-15 David Thompson Berg Composes de benzothiophene,formulations et utilisations de ceux-ci
US5792798A (en) * 1996-07-29 1998-08-11 Eli Lilly And Company Method for inhibiting plasminogen activator inhibitor 1
ZA9710262B (en) * 1996-11-19 1999-05-13 Lilly Co Eli Process for the synthesis of benzothiophenes
WO1998046588A2 (fr) * 1997-04-11 1998-10-22 Neorx Corporation Composes et therapies destines a la prevention d'affections vasculaires ou non vasculaires
IL146284A0 (en) 1999-05-04 2002-07-25 Strakan Ltd Androgen glycosides and pharmaceutical compositions containing the same
US6232260B1 (en) 1999-10-14 2001-05-15 Equistar Chemicals, L.P. Single-site catalysts for olefin polymerization
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
AU2003215380B2 (en) * 2002-02-22 2008-10-02 Bayer Pharmaceuticals Corporation Fused tricyclic heterocycles useful for treating hyper-proliferative disorders
US7144885B2 (en) * 2002-02-22 2006-12-05 Bayer Pharmaceuticals Corporation Fused tricyclic heterocycles useful for treating hyper-proliferative disorders
EP2316468A1 (fr) 2002-02-22 2011-05-04 Shire LLC Système de distribution et méthodes de protection et d'administration de dextroamphetamine
WO2008025509A1 (fr) * 2006-09-01 2008-03-06 Bayer Schering Pharma Aktiengesellschaft Dérivés de benzofurane et de benzothiophène utiles dans le traitement de cancers du système nerveux central
WO2011109679A2 (fr) * 2010-03-05 2011-09-09 Amira Pharmaceuticals, Inc. Inhibiteurs de la 5-lipoxygénase
CN102653520A (zh) * 2012-04-10 2012-09-05 苏州大学 一种2-羟基-2-芳基硫代乙酰胺的制备方法
KR20190062433A (ko) * 2016-09-27 2019-06-05 디에스엠 아이피 어셋츠 비.브이. 투명 연신 물품

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US5420349A (en) * 1994-06-10 1995-05-30 Eli Lilly And Company 2-amino-3-aroyl-benzo[β]thiophenes and methods for preparing and using same to produce 6-hydroxy-2-(4-hydroxyphenyl)-3-]benzo[4-(2-aminoethoxy)-benzoyl[β]thiophenes

Also Published As

Publication number Publication date
WO1995034557A1 (fr) 1995-12-21
PT765321E (pt) 2001-07-31
EP0765321A1 (fr) 1997-04-02
FI964914A0 (fi) 1996-12-09
US5792870A (en) 1998-08-11
DE69520738T2 (de) 2001-09-13
ATE200671T1 (de) 2001-05-15
US5466810A (en) 1995-11-14
AU2702995A (en) 1996-01-05
DE69520738D1 (de) 2001-05-23
GR3036028T3 (en) 2001-09-28
JPH10502057A (ja) 1998-02-24
FI964914A7 (fi) 1996-12-09
BR9507956A (pt) 1997-08-12
EP0765321A4 (fr) 1997-05-02
EP0765321B1 (fr) 2001-04-18
CA2192097A1 (fr) 1995-12-21
FI964914L (fi) 1996-12-09
ES2155891T3 (es) 2001-06-01
US5554755A (en) 1996-09-10

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