DK0765400T3 - Screening for inhibitorer af chitinase - Google Patents

Screening for inhibitorer af chitinase

Info

Publication number
DK0765400T3
DK0765400T3 DK95922239T DK95922239T DK0765400T3 DK 0765400 T3 DK0765400 T3 DK 0765400T3 DK 95922239 T DK95922239 T DK 95922239T DK 95922239 T DK95922239 T DK 95922239T DK 0765400 T3 DK0765400 T3 DK 0765400T3
Authority
DK
Denmark
Prior art keywords
chitinase
cells
screening
inhibitors
umbelliferyltriacetyl
Prior art date
Application number
DK95922239T
Other languages
English (en)
Inventor
Sanford Jay Silverman
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of DK0765400T3 publication Critical patent/DK0765400T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18Testing for antimicrobial activity of a material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • C12Q2334/20Coumarin derivatives
    • C12Q2334/224-Methylumbelliferyl, i.e. beta-methylumbelliferone, 4MU
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G01N2333/39Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
    • G01N2333/395Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts from Saccharomyces
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/924Hydrolases (3) acting on glycosyl compounds (3.2)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • G01N2400/24Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar beta-D-Glucans, i.e. having beta 1,n (n=3,4,6) linkages between saccharide units, e.g. xanthan
    • G01N2400/28Chitin, chitosan
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/94Saccharomyces
    • Y10S435/942Saccharomyces cerevisiae

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK95922239T 1994-06-14 1995-06-07 Screening for inhibitorer af chitinase DK0765400T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/259,409 US5561051A (en) 1994-06-14 1994-06-14 Screen for inhibitors of chitinase
PCT/US1995/007207 WO1995034678A1 (en) 1994-06-14 1995-06-07 Screen for inhibitors of chitinase

Publications (1)

Publication Number Publication Date
DK0765400T3 true DK0765400T3 (da) 2001-01-02

Family

ID=22984827

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95922239T DK0765400T3 (da) 1994-06-14 1995-06-07 Screening for inhibitorer af chitinase

Country Status (11)

Country Link
US (1) US5561051A (da)
EP (1) EP0765400B1 (da)
AT (1) ATE196320T1 (da)
AU (1) AU2699595A (da)
CA (1) CA2194983A1 (da)
DE (1) DE69518842T2 (da)
DK (1) DK0765400T3 (da)
ES (1) ES2151070T3 (da)
GR (1) GR3035076T3 (da)
PT (1) PT765400E (da)
WO (1) WO1995034678A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6512166B1 (en) 1991-06-17 2003-01-28 Cornell Research Foundation, Inc. Combinations of fungal cell wall degrading enzyme and fungal cell membrane affecting compound
US6300176B1 (en) 1994-07-22 2001-10-09 Semiconductor Energy Laboratory Co., Ltd. Laser processing method
EP0912757A4 (en) * 1996-05-14 2003-03-05 Univ Manitoba DETERMINATION OF BIOLOGICALLY ACTIVE SUBSTANCES USING SOLID PHASES
US20030017570A1 (en) 1996-06-14 2003-01-23 Patrick W. Gray Chitinase materials and methods
US6372446B1 (en) 1997-02-04 2002-04-16 Mycometer Aps Method of selectively determining a fungal biomass
DE19713572A1 (de) 1997-04-02 1998-10-22 Hoechst Ag Verfahren zum Screening von antimykotisch wirkenden Substanzen
US7070921B2 (en) 2000-04-28 2006-07-04 Molecular Devices Corporation Molecular modification assays
US7632651B2 (en) 1997-09-15 2009-12-15 Mds Analytical Technologies (Us) Inc. Molecular modification assays
US7745142B2 (en) 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US6982431B2 (en) 1998-08-31 2006-01-03 Molecular Devices Corporation Sample analysis systems
US6297018B1 (en) 1998-04-17 2001-10-02 Ljl Biosystems, Inc. Methods and apparatus for detecting nucleic acid polymorphisms
US5997846A (en) * 1997-11-17 1999-12-07 Albert Einstein College Of Medicine Of Yeshiva University Method for detecting arthropods
US6200951B1 (en) 1998-03-12 2001-03-13 Icos Corporation Chitinase chitin-binding fragments
US6037333A (en) * 1998-05-07 2000-03-14 Trustees Of Tufts College Microbe-inhibiting compositions
CN115747298B (zh) * 2022-10-10 2023-10-27 浙江大学 昆虫烟酰胺酶抑制剂及鉴定方法及用于杀虫剂的用途

Also Published As

Publication number Publication date
AU2699595A (en) 1996-01-05
EP0765400A1 (en) 1997-04-02
US5561051A (en) 1996-10-01
GR3035076T3 (en) 2001-03-30
ATE196320T1 (de) 2000-09-15
DE69518842T2 (de) 2001-04-19
WO1995034678A1 (en) 1995-12-21
CA2194983A1 (en) 1995-12-21
EP0765400B1 (en) 2000-09-13
PT765400E (pt) 2001-03-30
ES2151070T3 (es) 2000-12-16
DE69518842D1 (de) 2000-10-19

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