DK0769068T3 - Samtidig detektion, identifikation og differentiering af eubakterielle taxa ved anvendelse af et hybridiseringsassay - Google Patents

Samtidig detektion, identifikation og differentiering af eubakterielle taxa ved anvendelse af et hybridiseringsassay

Info

Publication number
DK0769068T3
DK0769068T3 DK95924923T DK95924923T DK0769068T3 DK 0769068 T3 DK0769068 T3 DK 0769068T3 DK 95924923 T DK95924923 T DK 95924923T DK 95924923 T DK95924923 T DK 95924923T DK 0769068 T3 DK0769068 T3 DK 0769068T3
Authority
DK
Denmark
Prior art keywords
identification
hybridization
sample
wash conditions
micro
Prior art date
Application number
DK95924923T
Other languages
English (en)
Inventor
Heuverswyn Hugo Van
Geert Jannes
Rudi Rossau
Original Assignee
Innogenetics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innogenetics Nv filed Critical Innogenetics Nv
Application granted granted Critical
Publication of DK0769068T3 publication Critical patent/DK0769068T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK95924923T 1994-06-24 1995-06-23 Samtidig detektion, identifikation og differentiering af eubakterielle taxa ved anvendelse af et hybridiseringsassay DK0769068T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94870106 1994-06-24
EP95870032 1995-04-07

Publications (1)

Publication Number Publication Date
DK0769068T3 true DK0769068T3 (da) 2006-02-27

Family

ID=26137770

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95924923T DK0769068T3 (da) 1994-06-24 1995-06-23 Samtidig detektion, identifikation og differentiering af eubakterielle taxa ved anvendelse af et hybridiseringsassay

Country Status (13)

Country Link
US (4) US6025132A (da)
EP (5) EP1091004B1 (da)
JP (1) JP3833703B2 (da)
AT (2) ATE306560T1 (da)
AU (1) AU2924695A (da)
BR (1) BR9508101A (da)
CA (1) CA2193101C (da)
CZ (1) CZ291483B6 (da)
DE (2) DE69535923D1 (da)
DK (1) DK0769068T3 (da)
ES (2) ES2323161T3 (da)
RU (1) RU2154106C2 (da)
WO (1) WO1996000298A1 (da)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0452596A1 (en) 1990-04-18 1991-10-23 N.V. Innogenetics S.A. Hybridization probes derived from the spacer region between the 16S and 23S rRNA genes for the detection of non-viral microorganisms
EP1091004B1 (en) * 1994-06-24 2009-02-25 Innogenetics N.V. Simultaneous detection, identification and differentiation of Mycobacterium species using a hybridization assay
US6001564A (en) * 1994-09-12 1999-12-14 Infectio Diagnostic, Inc. Species specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US20020055101A1 (en) 1995-09-11 2002-05-09 Michel G. Bergeron Specific and universal probes and amplification primers to rapidly detect and identify common bacterial pathogens and antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US5994066A (en) * 1995-09-11 1999-11-30 Infectio Diagnostic, Inc. Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US5849488A (en) * 1996-02-27 1998-12-15 Oulutech Ltd. DNA-sequence-based diagnosis of mastitis from a milk sample
US20030049636A1 (en) 1999-05-03 2003-03-13 Bergeron Michel G. Species-specific, genus-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial and fungal pathogens and associated antibiotic resistance genes from clinical specimens for diagnosis in microbiology laboratories
US20100267012A1 (en) 1997-11-04 2010-10-21 Bergeron Michel G Highly conserved genes and their use to generate probes and primers for detection of microorganisms
US6465638B2 (en) 1997-06-25 2002-10-15 Ortho-Clinical Diagnostics, Inc. Multiplexed PCR assay for detecting disseminated Mycobacterium avium complex infection
US7060458B1 (en) * 1997-08-14 2006-06-13 Wyeth Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics
DE19739611A1 (de) * 1997-09-09 1999-03-11 Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh Nucleinsäure-Sequenzen und Verfahren zum Nachweis von Bakterien der Gattung Pseudomonas
WO1999022023A2 (de) * 1997-10-29 1999-05-06 Mira Diagnostica Gmbh Verfahren zum nachweis von mikroorganismen
US6004754A (en) * 1998-01-21 1999-12-21 Becton Dickinson And Company DNA sequence, related probes and primers for the detection of Streptococcus agalactiae
US6261769B1 (en) * 1998-03-31 2001-07-17 The United States Of America As Represented By The Secretary Of Agriculture Intergenic spacer target sequence for detecting and distinguishing Chlamydial species or strains
ES2313793T3 (es) * 1998-09-24 2009-03-01 Innogenetics N.V. Identificacion de microorganismos que causan las infecciones agudas del tracto respiratorio.
GB9904804D0 (en) * 1999-03-02 1999-04-28 King S College London Identification of bacteria
US6821770B1 (en) * 1999-05-03 2004-11-23 Gen-Probe Incorporated Polynucleotide matrix-based method of identifying microorganisms
US20030207313A1 (en) * 1999-05-29 2003-11-06 Kim Cheol Min Oligonucleotide for detection and identification of Mycobacteria
CA2937907C (en) * 1999-09-28 2017-08-22 Geneohm Sciences Canada Inc. Nucleic acids, methods and kits for the detection of campylobacter
US6261785B1 (en) 2000-07-27 2001-07-17 Becton, Dickinson And Company Amplification and detection of Bordetella pertussis
CA2416952A1 (en) * 2000-07-27 2002-02-07 The Australian National University Combinatorial probes and uses therefor
CA2931751A1 (en) * 2001-11-02 2003-05-15 Gen-Probe Incorporated Compositions, methods and kits for determining the presence of mycoplasma pneumoniae and/or mycoplasma genitalium in a test sample
WO2003066893A1 (de) * 2002-02-04 2003-08-14 Vermicon Ag Verfahren zum spezifischen schnellnachweis pathogener lebensmittelrelevanter bakterien
ES2372048T3 (es) * 2002-12-06 2012-01-13 Innogenetics N.V. Detección, identificación y diferenciación de taxones eubacterianos empleando un ensayo de hibridación.
EP1426447A1 (en) * 2002-12-06 2004-06-09 Roche Diagnostics GmbH Method for the detection of pathogenic gram positive bacteria selected from the genera Staphylococcus, Enterococcus and Streptococcus
US20060115819A1 (en) * 2002-12-06 2006-06-01 Sofie Claeys Detection, identification and differentiation of eubacterial taxa using a hybridization assay
JP4377375B2 (ja) 2002-12-06 2009-12-02 エフ．ホフマン−ラ ロシュ アーゲー 病原性生物の多重分析検出
WO2004059281A2 (en) * 2002-12-16 2004-07-15 Avery Dennison Corporation Analyte detecting article and method
US7967756B2 (en) * 2003-09-18 2011-06-28 Cardiac Pacemakers, Inc. Respiratory therapy control based on cardiac cycle
TWI361490B (en) * 2003-09-05 2012-04-01 Renesas Electronics Corp A semiconductor device and a method of manufacturing the same
WO2005045074A2 (en) * 2003-11-05 2005-05-19 Stichting Voor De Technische Wetenschappen Means and methods for classifying cyanobacteria
US8227192B2 (en) 2003-11-26 2012-07-24 Advandx, Inc. Peptide nucleic acid probes for analysis of certain Staphylococcus species
WO2005054516A2 (en) * 2003-11-26 2005-06-16 Advandx, Inc. Peptide nucleic acid probes for analysis of certain staphylococcus species
US7429464B2 (en) * 2003-12-09 2008-09-30 Biomerieux, Inc. Methods for detecting bacterial pathogens
DE602004019564D1 (de) * 2003-12-09 2009-04-02 Bio Merieux Inc Verfahren zum nachweis bakterieller krankheitserreger
WO2005056817A2 (en) * 2003-12-09 2005-06-23 Biomerieux, Inc. Method for recovering microorganisms from a sample
KR100615424B1 (ko) * 2004-01-14 2006-08-25 김철민 마이코플라즈마 및 유사 균종의 유전자형 감별을 위한올리고뉴클레오티드, 이를 포함하는 마이크로어레이와이를 이용한 균종 검출 방법
CA2553270C (en) * 2004-02-06 2016-08-23 Innogenetics N.V. Detection, identification and differentiation of proteus species using the spacer region
JP4788942B2 (ja) * 2004-02-23 2011-10-05 独立行政法人産業技術総合研究所 特定生物種検出のためのデオキシリボザイム
RU2270254C2 (ru) * 2004-04-30 2006-02-20 Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук Способ идентификации трансгенных последовательностей днк в растительном материале и продуктах на его основе, набор олигонуклеотидов и биочип для осуществления этого способа
US7332597B2 (en) 2004-06-28 2008-02-19 University Of Kentucky Research Foundation Primers and probe to identify mycobacterium tuberculosis complex
RU2279078C2 (ru) * 2004-07-19 2006-06-27 Государственное образовательное учреждение высшего профессионального образования Санкт-Петербургская государственная медицинская академия им. И.И. Мечникова Способ оценки выраженности нарушений микробиоценоза в культе желудка после его резекции
US7309589B2 (en) 2004-08-20 2007-12-18 Vironix Llc Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing
KR100850193B1 (ko) * 2004-08-28 2008-08-04 주식회사 진인 모든 세균의 감별을 위한 세균 특이적, 속 특이적 및 종특이적 올리고뉴클레오티드, 이를 포함하는 진단 키트, 및이를 이용한 검출 방법
US20060099618A1 (en) * 2004-09-30 2006-05-11 Innogenetics, N.V. Detection, identification and differentiation of Serratia species using the spacer region
US20060204995A1 (en) * 2005-03-08 2006-09-14 Oh Ji-Young Method of designing probe set, probe set designed by the method, microarray comprising the probe set, computer readable medium recorded thereon program to execute the method, and method of identifying target sequence using the probe set
CA2606253A1 (en) * 2005-04-21 2006-10-26 Uti Limited Partnership Pcr for mrsa sccmec typing
US7855051B2 (en) * 2005-09-12 2010-12-21 Research & Diagnostic Systems, Inc. Mycoplasma detection method and composition
US7531309B2 (en) 2005-12-06 2009-05-12 Michigan State University PCR based capsular typing method
US7819615B2 (en) * 2005-12-06 2010-10-26 Hewlett-Packard Development Method and apparatus for finishing sheets for a bound document
RU2299908C1 (ru) * 2005-12-26 2007-05-27 Федеральное Государственное учреждение науки "Московский научно-исследовательский институт эпидемиологии и микробиологии им. Г.Н. Габричевского" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека Способ дифференциации штаммов bordetella pertussis
KR100707213B1 (ko) * 2006-03-21 2007-04-13 삼성전자주식회사 마이크로어레이용 프로브 선택 방법 및 장치
CN101490278A (zh) * 2006-05-16 2009-07-22 麒麟麦酒株式会社 用于检测德克醇母或酒香酵母的引物组
RU2348695C2 (ru) 2006-05-23 2009-03-10 Закрытое акционерное общество "Молекулярно-медицинские технологии" Дифференцирующий и специфический олигонуклеотиды для идентификации последовательностей днк инфекционных агентов в биологических материалах, способ видовой идентификации инфекционных агентов, биочип и набор для осуществления этого способа
RU2354700C2 (ru) * 2006-05-26 2009-05-10 Ооо "Научно-Производственная Фирма "Омикс" Набор родо- и видоспецифичных олигонуклеотидных праймеров для детекции и видовой идентификации иерсиний методом мультиплексной полимеразной цепной реакции
CN101627133A (zh) * 2007-01-08 2010-01-13 株式会社美迪基尼斯 用于金黄色葡萄球菌检测的dna芯片
US20100167956A1 (en) * 2007-01-08 2010-07-01 Medigenes Co., Ltd. Dna chip for detection of escherichia coli
JP2010524454A (ja) 2007-04-19 2010-07-22 モレキュラー ディテクション インコーポレーテッド 抗生物質耐性細菌の検出および分析のための方法、組成物、およびキット
ITMI20071410A1 (it) * 2007-07-13 2009-01-14 Univ Firenze Test in biologia molecolare su campioni biologici per la diagnosi e tipizzazione di germi causa di malattie invasive
RU2010144789A (ru) * 2008-04-01 2012-05-10 Метаметрикс Клиникал Лэборетери (Us) Процесс и способ мониторинга желудочно-кишечной микрофлоры
US20090253128A1 (en) * 2008-04-03 2009-10-08 Centers For Disease Control Department Of Healthy Nucleotide sequence for identifying of acinetobacter bacteria, and method and kit of identification of acinetobacter bacteria
DK2362915T3 (da) * 2008-11-07 2017-03-27 Dupont Nutrition Biosci Aps Crispr-sekvenser fra bifidobakterier
JP5768282B2 (ja) 2008-12-10 2015-08-26 ユニヴァーシティ オブ ワシントン ｒＲＮＡ前駆体のレシオメトリック分析
RU2455364C2 (ru) * 2010-07-02 2012-07-10 Федеральное государственное образовательное учреждение высшего профессионального образования "Белгородская государственная сельскохозяйственная академия" Способ идентификации микобактерий с помощью полимеразной цепной реакции
RU2486251C2 (ru) * 2011-08-25 2013-06-27 Учреждение Российской академии наук Институт биохимии им. А.Н. Баха РАН (ИНБИ РАН) Способ идентификации и дифференциации прокариотических организмов
TWI614345B (zh) 2012-06-22 2018-02-11 Taichung Veterans General Hospital 檢測數種非結核分枝桿菌、結核分枝桿菌及其抗藥性之探針、晶片、套組與方法
PL223163B1 (pl) * 2012-10-04 2016-10-31 Gdański Univ Medyczny Zestaw sond i starterów do wykrywania bakterii z gatunku Acinetobacter baumannii, sposób oraz zestaw do analizy próbek medycznych i środowiskowych
TWI470083B (en) * 2012-10-23 2015-01-21 Oligonucleotide probe and biochip for identifying mycobacteria and the identification method thereof
CN109929937B (zh) * 2019-04-01 2023-04-21 广东省科学院动物研究所 龟嗜皮菌特异性鉴定引物、试剂盒及其鉴定方法
CN111647675A (zh) * 2020-06-03 2020-09-11 张家口富熙生物科技有限公司 一种用于rna恒温扩增检测布氏杆菌的引物和探针、试剂盒及检测方法
RU2765829C1 (ru) * 2021-04-27 2022-02-03 Федеральное государственное бюджетное образовательное учреждение высшего образования «Казанская государственная академия ветеринарной медицины имени Н.Э. Баумана» (RU) Набор высокоспецифичных олигонуклеотидных праймеров и зондов для детекции и дифференциации нетуберкулезных микобактерий
WO2026019326A1 (en) * 2024-07-18 2026-01-22 Biomiris Capital Group B.V. Probe-resolved melting curve analysis for identifying microorganisms in clinical samples

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US571095A (en) * 1896-11-10 Air-brake
FR651505A (fr) 1928-03-20 1929-02-20 Dispositif de blocage pour tambours d'enroulement
US4508823A (en) * 1980-05-08 1985-04-02 Microlife Technics, Inc. Gene splicing method and products produced therefrom
DK275685D0 (da) * 1985-06-18 1985-06-18 Benzon As Alfred Stabilisering af biologiske systemer
US5212059A (en) * 1988-01-11 1993-05-18 Microprobe Corporation Oligonucleotide probes for the detection of periodontal pathogens
WO1989010411A1 (fr) * 1988-04-20 1989-11-02 Fuso Yakuhin Kogyo Kabushiki Kaisha Procede de diagnostic de maladies infectieuses et procede de detection et d'identification de microorganismes
IE81145B1 (en) * 1989-04-20 2000-05-03 Thomas Gerard Barry Generation of specific probes for target nucleotide sequences
FR2651505B1 (fr) * 1989-09-06 1994-07-22 Pasteur Institut Fragments d'acides nucleiques derives d'un genome de mycobacterie appropriee, leurs applications dans le diagnostic des infections a mycobacteries et plasmides contenant lesdits fragments.
CA2033718A1 (en) * 1990-01-19 1991-07-20 F. Hoffmann-La Roche Ag Process for detection of water-borne microbial pathogens and indicators of human fecal contamination in water samples and kits therefor
EP0452596A1 (en) * 1990-04-18 1991-10-23 N.V. Innogenetics S.A. Hybridization probes derived from the spacer region between the 16S and 23S rRNA genes for the detection of non-viral microorganisms
US5536638A (en) * 1990-04-18 1996-07-16 N.V. Innogenetics S.A. Hybridization probes derived from the spacer region between the 16S and 23S rRNA genes for the detection of Neisseria gonorrhoeae
US5627032A (en) * 1990-12-24 1997-05-06 Ulanovsky; Levy Composite primers for nucleic acids
EP0497464A1 (en) 1991-01-31 1992-08-05 Amoco Corporation Rapid microbial diagnostics by in situ hybridization in aqueous suspension
ZA92278B (en) * 1991-02-01 1992-10-28 Akzo Nv 3-quinuclidine derivatives
EP0499003A1 (en) * 1991-02-14 1992-08-19 N.V. Innogenetics S.A. Polypeptides and peptides, particularly recombinant polypeptides and peptides, nucleic acids coding for the same and use of these polypeptides and peptides in the diagnosis of tuberculosis
EP0579597A1 (en) * 1991-03-22 1994-01-26 The University Of British Columbia Nucleic acid probes useful for the detection of mycobacterium tuberculosis
US5521300A (en) * 1991-08-13 1996-05-28 Norval B. Galloway Oligonucleotides complementary to mycobacterial nucleic acids
FR2683227B1 (fr) * 1991-10-31 1994-03-04 Pasteur Institut Sequences nucleotidiques hybridant avec les souches bacteriennes du complexe mycobacterium avium-intracellulare, leur utilisation comme amorces oligonucleotidiques et sondes nucleiques.
IL103935A0 (en) * 1991-12-04 1993-05-13 Du Pont Method for the identification of microorganisms by the utilization of directed and arbitrary dna amplification
US5631130A (en) * 1994-05-13 1997-05-20 Abbott Laboratories Materials and methods for the detection of Mycobacterium tuberculosis
US5712095A (en) * 1994-06-16 1998-01-27 Becton Dickinson And Company Rapid and sensitive detection of antibiotic-resistant mycobacteria using oligonucleotide probes specific for ribosomal RNA precursors
EP1091004B1 (en) 1994-06-24 2009-02-25 Innogenetics N.V. Simultaneous detection, identification and differentiation of Mycobacterium species using a hybridization assay
WO1996019585A1 (en) * 1994-12-20 1996-06-27 Heidelberg Repatriation Hospital Typing of microorganisms
US6737248B2 (en) * 1996-01-05 2004-05-18 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences
US6593114B1 (en) * 1996-01-05 2003-07-15 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences
US5849488A (en) * 1996-02-27 1998-12-15 Oulutech Ltd. DNA-sequence-based diagnosis of mastitis from a milk sample

Also Published As

Publication number Publication date
EP1088899A2 (en) 2001-04-04
EP1091004A3 (en) 2001-04-18
EP1091004A2 (en) 2001-04-11
WO1996000298A1 (en) 1996-01-04
US6811978B2 (en) 2004-11-02
CZ381996A3 (cs) 1998-04-15
CA2193101A1 (en) 1996-01-04
HK1037687A1 (en) 2003-09-17
AU2924695A (en) 1996-01-19
US7390623B2 (en) 2008-06-24
BR9508101A (pt) 1997-12-30
US6025132A (en) 2000-02-15
EP1098007A1 (en) 2001-05-09
DE69534516T2 (de) 2006-06-29
ATE423853T1 (de) 2009-03-15
EP0769068B1 (en) 2005-10-12
CA2193101C (en) 2010-03-23
US20030215802A1 (en) 2003-11-20
EP1098006A1 (en) 2001-05-09
JP3833703B2 (ja) 2006-10-18
ATE306560T1 (de) 2005-10-15
EP1088899A3 (en) 2001-05-02
ES2323161T3 (es) 2009-07-08
RU2154106C2 (ru) 2000-08-10
DE69534516D1 (de) 2005-11-17
US6312903B1 (en) 2001-11-06
JPH10501976A (ja) 1998-02-24
EP1091004B1 (en) 2009-02-25
DE69535923D1 (de) 2009-04-09
US20050142575A1 (en) 2005-06-30
CZ291483B6 (cs) 2003-03-12
EP0769068A1 (en) 1997-04-23
ES2250971T3 (es) 2006-04-16

Similar Documents

Publication Publication Date Title
BR9508101A (pt) Detecção identificação e diferenciação simultánea de taxa eubacterial usando um ensaio de hibridização
DE69532675D1 (de) Verfahren zum nachweis des antibiotikaresistenzspektrums von mykobakterium spezies
CA2217325A1 (en) Nucleic acid detection and amplification by chemical linkage of oligonucleotides
WO2001049883A3 (en) Amplification based polymorphism detection
AU2709995A (en) Method of amplification for increasing the sensitivity of detecting nucleic acid-probe target hybrids
WO1999037806A3 (en) Modified nucleic acid probes and uses thereof
DE69230305D1 (de) Primerpaar zum Nachweis von Mycobacterium
ATE398186T1 (de) Integriertes verfahren und system zur amplifizierung und zum nachweis von nukleinsäuren
DE60333480D1 (de) Verfahren zum nachweis von pathogenen organismen
DE50209977D1 (de) Nachweis und differenzierung von mikroorganismen der spezies yersinia pestis/yersinia pseudotuberculosis
WO1995033854B1 (en) Use of a specific marker for detection of salmonella with pcr
ATE184055T1 (de) Verfahren zum sensitiven nachweis von reverser transcriptase
ATE207544T1 (de) Amplikationsprimern und nukleinsäuresonden zum nachweis von coccidioides immites
EP0810291A4 (en) PROBE FOR USE IN NUCLEIC ACID ANALYSIS AND METHOD OF DETECTION
DK0689609T4 (da) Fremgangsmåde til typisering af HLA-B under anvendelse af specifikke primere og probesæt
DE69122800D1 (de) Nucleinsäure-Proben und Verfahren zum Nachweis von Giardia Lamblia
CA2549059A1 (en) Oligonucleotides for the detection of hepatitis b virus
ATE191512T1 (de) Nukleinsäure sonden welche bei nachweis von shigellabakterien verwendbar sind
WO1998016658A3 (en) Probes, methods and kits for detection and typing of helicobacter pylori nucleic acids in biological samples
WO1993022459A3 (en) Oligonucleotides and nucleic acids for detection of ureaplasma urealyticum
WO2000065092A3 (en) Blocking non-specific binding of granulocytes in microorganism detection
WO2001075173A3 (en) β 2 ADRENERGIC POLYMORPHISM DETECTION
ATE423855T1 (de) Oligonukleotide zum nachweis von leishmaniase und verfahren dafür