DK0793721T3 - Peptider, der er i stand til at binde sig til GAP-proteinets SH3-domæne, nukleotidsekvenser, der koder derfor, fremstilling og anvendelse deraf - Google Patents

Peptider, der er i stand til at binde sig til GAP-proteinets SH3-domæne, nukleotidsekvenser, der koder derfor, fremstilling og anvendelse deraf

Info

Publication number: DK0793721T3
Authority: DK; Denmark
Prior art keywords: domain; binding; production; nucleotide sequences; sequences encoding
Prior art date: 1994-11-22

Application number

DK95941126T

Other languages

English (en)

Inventor

Fabien Schweighoffer

Fabienne Parker

Bruno Tocque

Marc Duchesne

Didier Faucher

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-22

Filing date

1995-11-22

Publication date

2006-01-30

1994-11-22 Priority claimed from FR9413955A external-priority patent/FR2727116B1/fr

1995-05-16 Priority claimed from FR9505753A external-priority patent/FR2734266B1/fr

1995-11-22 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2006-01-30 Application granted granted Critical

2006-01-30 Publication of DK0793721T3 publication Critical patent/DK0793721T3/da

Links

102000018898 GTPase-Activating Proteins Human genes 0.000 title abstract 2
108010027920 GTPase-Activating Proteins Proteins 0.000 title abstract 2
102000000395 SH3 domains Human genes 0.000 title abstract 2
108050008861 SH3 domains Proteins 0.000 title abstract 2
108091028043 Nucleic acid sequence Proteins 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
150000007523 nucleic acids Chemical group 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
- C07K14/4706—Guanosine triphosphatase activating protein, GAP
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Zoology (AREA)
Toxicology (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Hematology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Enzymes And Modification Thereof (AREA)

DK95941126T 1994-11-22 1995-11-22 Peptider, der er i stand til at binde sig til GAP-proteinets SH3-domæne, nukleotidsekvenser, der koder derfor, fremstilling og anvendelse deraf DK0793721T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9413955A FR2727116B1 (fr)	1994-11-22	1994-11-22	Peptides capables de se lier au domaine sh3 de la proteine gap, sequences nucleotidiques codant pour ces peptides, leur preparation et utilisation
FR9505753A FR2734266B1 (fr)	1995-05-16	1995-05-16	Peptides capables de se lier au domaine sh3 de la proteine gap sequences nucleotidiques codant pour ces peptides, leur preparation et utilisation

Publications (1)

Publication Number	Publication Date
DK0793721T3 true DK0793721T3 (da)	2006-01-30

Family

ID=26231549

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95941126T DK0793721T3 (da)	1994-11-22	1995-11-22	Peptider, der er i stand til at binde sig til GAP-proteinets SH3-domæne, nukleotidsekvenser, der koder derfor, fremstilling og anvendelse deraf

Country Status (18)

Country	Link
US (1)	US5886150A (da)
EP (1)	EP0793721B1 (da)
JP (2)	JPH10509044A (da)
AT (1)	ATE305037T1 (da)
AU (1)	AU713937B2 (da)
BR (1)	BR9510067A (da)
CA (1)	CA2204438A1 (da)
CZ (1)	CZ292538B6 (da)
DE (1)	DE69534471T2 (da)
DK (1)	DK0793721T3 (da)
ES (1)	ES2248800T3 (da)
FI (1)	FI972170A0 (da)
HU (1)	HU221410B1 (da)
IL (1)	IL116026A (da)
MX (1)	MX9703364A (da)
NO (1)	NO972313D0 (da)
SK (1)	SK287034B6 (da)
WO (1)	WO1996016169A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2780062B1 (fr) *	1998-06-17	2000-07-28	Rhone Poulenc Rorer Sa	Anticorps monoclonaux diriges contre la proteine g3bp, et leurs utilisations
PT1783222E (pt)	1998-10-23	2012-07-26	Kirin Amgen Inc	Péptidos diméricos de trombopoietina que simulam a ligação ao receptor mpl e têm actividade trombopoiética
US6864355B1 (en)	2000-05-02	2005-03-08	Yale University	Inhibition of NF-κB activation by blockade of IKKβ-NEMO interactions at the NEMO binding domain
AU2001266070A1 (en) *	2000-06-16	2001-12-24	Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V.	Method for identifying apoptosis-modified proteins
JP2004532981A (ja) *	2001-04-10	2004-10-28	チルドレンズメディカルセンターコーポレーション	タンパク質−タンパク質相互作用の解析および標識の方法
US20050069999A1 (en) *	2001-07-09	2005-03-31	Sharma Sreenath V	Sh3 domain binding inhibitors
WO2003006060A1 (en) *	2001-07-09	2003-01-23	Kyowa Hakko Kogyo Co., Ltd.	Sh3 domain binding inhibitors
AUPR721101A0 (en) *	2001-08-23	2001-09-13	University Of Queensland, The	Nucleic acid and polypeptide linked to breast cancer
WO2006010057A2 (en) *	2004-07-08	2006-01-26	Amgen Inc.	Therapeutic peptides
EA011879B1 (ru)	2004-09-24	2009-06-30	Эмджин Инк.	МОЛЕКУЛЫ С МОДИФИЦИРОВАННЫМ Fc ФРАГМЕНТОМ
US8008453B2 (en)	2005-08-12	2011-08-30	Amgen Inc.	Modified Fc molecules
US9283260B2 (en)	2006-04-21	2016-03-15	Amgen Inc.	Lyophilized therapeutic peptibody formulations
US11237168B2 (en)	2019-06-26	2022-02-01	St. Jude Children's Research Hospital	Method for identifying modulators of G3BP activity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA894726B (en) *	1988-06-27	1990-03-28	Akzo Nv	Coccidiosis vaccine
WO1991002749A1 (en) *	1989-08-21	1991-03-07	Cetus Corporation	PEPTIDES FROM GTPase-ACTIVATING PROTEIN (GAP) AND DIAGNOSTIC AND THERAPEUTIC USE THEREOF
CA2057675A1 (en) *	1990-12-24	1992-06-25	Michael D. Schaber	Peptide inhibitors of ras-gap interaction
FR2694296B1 (fr) *	1992-07-30	1994-09-02	Rhone Poulenc Rorer Sa	Peptides inhibant l'activité des protéines ras, préparation et utilisation.
WO1994016069A2 (en) *	1993-01-15	1994-07-21	Schering Corporation	Ras associated gap proteins

1995
- 1995-11-16 IL IL11602695A patent/IL116026A/xx not_active IP Right Cessation
- 1995-11-22 EP EP95941126A patent/EP0793721B1/fr not_active Expired - Lifetime
- 1995-11-22 FI FI972170A patent/FI972170A0/fi not_active Application Discontinuation
- 1995-11-22 CZ CZ19971545A patent/CZ292538B6/cs not_active IP Right Cessation
- 1995-11-22 BR BR9510067A patent/BR9510067A/pt not_active Application Discontinuation
- 1995-11-22 CA CA002204438A patent/CA2204438A1/fr not_active Abandoned
- 1995-11-22 JP JP8516632A patent/JPH10509044A/ja not_active Ceased
- 1995-11-22 AU AU42636/96A patent/AU713937B2/en not_active Ceased
- 1995-11-22 HU HU9702079A patent/HU221410B1/hu not_active IP Right Cessation
- 1995-11-22 DK DK95941126T patent/DK0793721T3/da active
- 1995-11-22 DE DE69534471T patent/DE69534471T2/de not_active Expired - Lifetime
- 1995-11-22 ES ES95941126T patent/ES2248800T3/es not_active Expired - Lifetime
- 1995-11-22 AT AT95941126T patent/ATE305037T1/de not_active IP Right Cessation
- 1995-11-22 SK SK629-97A patent/SK287034B6/sk not_active IP Right Cessation
- 1995-11-22 US US08/836,791 patent/US5886150A/en not_active Expired - Fee Related
- 1995-11-22 WO PCT/FR1995/001539 patent/WO1996016169A1/fr not_active Ceased
- 1995-11-22 MX MX9703364A patent/MX9703364A/es not_active IP Right Cessation
1997
- 1997-05-21 NO NO972313A patent/NO972313D0/no not_active Application Discontinuation
2005
- 2005-10-25 JP JP2005309422A patent/JP2006122049A/ja active Pending

Also Published As

Publication number	Publication date
JPH10509044A (ja)	1998-09-08
SK62997A3 (en)	1998-02-04
NO972313L (no)	1997-05-21
CA2204438A1 (fr)	1996-05-30
IL116026A0 (en)	1996-01-31
IL116026A (en)	2005-08-31
MX9703364A (es)	1997-08-30
BR9510067A (pt)	1997-12-30
HUT77029A (hu)	1998-03-02
CZ292538B6 (cs)	2003-10-15
AU713937B2 (en)	1999-12-16
EP0793721B1 (fr)	2005-09-21
FI972170A7 (fi)	1997-05-21
EP0793721A1 (fr)	1997-09-10
AU4263696A (en)	1996-06-17
US5886150A (en)	1999-03-23
CZ154597A3 (en)	1997-10-15
HU221410B1 (en)	2002-09-28
JP2006122049A (ja)	2006-05-18
FI972170L (fi)	1997-05-21
NO972313D0 (no)	1997-05-21
ES2248800T3 (es)	2006-03-16
WO1996016169A1 (fr)	1996-05-30
SK287034B6 (sk)	2009-10-07
FI972170A0 (fi)	1997-05-21
ATE305037T1 (de)	2005-10-15
DE69534471D1 (de)	2006-02-02
DE69534471T2 (de)	2006-06-22

Publication	Publication Date	Title
ATE389724T1 (de)	2008-04-15	Menschliche dnase i hyperaktive varianten
DK0793721T3 (da)	2006-01-30	Peptider, der er i stand til at binde sig til GAP-proteinets SH3-domæne, nukleotidsekvenser, der koder derfor, fremstilling og anvendelse deraf
DK0719328T3 (da)	2000-11-13	Genet GRB 3-3, varianter deraf og anvendelse deraf
ATE443761T1 (de)	2009-10-15	Rtd receptor
MX9806041A (es)	1998-11-30	Proteina purificada sr-p70.
SE9602822D0 (sv)	1996-07-19	New receptor
DK0939769T3 (da)	2006-03-13	Vertebrat-Smoothened-proteiner
PT1141305E (pt)	2006-10-31	Gene quimerico formado pelas sequencias de adn que codifica os determinantes antigenicos de quatro proteinas de l. infantum
ATE215123T1 (de)	2002-04-15	Or-1, ein wais-rezeptor der nuklearen rezeptoren familie
DE69529235D1 (de)	2003-01-30	Menschliche dnase i varianten
ATE358682T1 (de)	2007-04-15	Klonierte rezeptoren des glukagon-ähnlichen peptids-2
ES2059801T3 (es)	1994-11-16	Nuevas linfoquinas, secuencias de adn que codifican para estas linfoquinas, y composiciones farmaceuticas conteniendo estas linfoquinas.
DK0938555T3 (da)	2005-05-23	Konstruktioner og komplekser af cyclin E
SE9604439D0 (sv)	1996-12-02	New receptor
BG101847A (bg)	1998-07-31	Варианти на човешка дезоксирибонуклеаза i
HUP0102540A2 (hu)	2001-10-28	Új angiotenzin-receptor, eljárás előállítására és alkalmazása
ATE104344T1 (de)	1994-04-15	Gereinigte ubiquitin-hydrolase, diese kodierende dns-sequenzen und ihre verwendung zur gewinnung von polypeptiden.
ECSP972331A (es)	1998-12-14	Muteinas de la obesidad