DK0801559T3 - Fremgangsmåde til fremstilling af orale doseringsformer indeholdende et beta-lactam antibiotikum - Google Patents

Fremgangsmåde til fremstilling af orale doseringsformer indeholdende et beta-lactam antibiotikum

Info

Publication number
DK0801559T3
DK0801559T3 DK96904039T DK96904039T DK0801559T3 DK 0801559 T3 DK0801559 T3 DK 0801559T3 DK 96904039 T DK96904039 T DK 96904039T DK 96904039 T DK96904039 T DK 96904039T DK 0801559 T3 DK0801559 T3 DK 0801559T3
Authority
DK
Denmark
Prior art keywords
pct
beta
lactam antibiotic
preparation
granulate
Prior art date
Application number
DK96904039T
Other languages
Danish (da)
English (en)
Inventor
Koutrik Robertus Cornelis Van
Gerrit Jan Sijbrands
Original Assignee
Yamanouchi Europ Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Europ Bv filed Critical Yamanouchi Europ Bv
Application granted granted Critical
Publication of DK0801559T3 publication Critical patent/DK0801559T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DK96904039T 1995-02-08 1996-02-08 Fremgangsmåde til fremstilling af orale doseringsformer indeholdende et beta-lactam antibiotikum DK0801559T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95200313 1995-02-08
PCT/EP1996/000547 WO1996024337A1 (en) 1995-02-08 1996-02-08 ORAL DOSAGE-FORMS CONTAINING A β-LACTAM ANTIBIOTIC

Publications (1)

Publication Number Publication Date
DK0801559T3 true DK0801559T3 (da) 2002-06-17

Family

ID=8220003

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96904039T DK0801559T3 (da) 1995-02-08 1996-02-08 Fremgangsmåde til fremstilling af orale doseringsformer indeholdende et beta-lactam antibiotikum

Country Status (19)

Country Link
US (1) US5948422A (de)
EP (1) EP0801559B1 (de)
CN (1) CN1125636C (de)
AT (1) ATE216576T1 (de)
AU (1) AU4789696A (de)
BG (1) BG63528B1 (de)
BR (1) BR9607189A (de)
CZ (1) CZ293718B6 (de)
DE (1) DE69620866T2 (de)
DK (1) DK0801559T3 (de)
EA (2) EA003736B1 (de)
ES (1) ES2175073T3 (de)
HU (1) HU227938B1 (de)
MX (1) MX9706062A (de)
NO (1) NO319993B1 (de)
PL (1) PL186386B1 (de)
PT (1) PT801559E (de)
WO (1) WO1996024337A1 (de)
ZA (1) ZA961018B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI225402B (en) * 1996-03-13 2004-12-21 Biochemie Gmbh Auxiliary-free agglomerates
EP0912169A2 (de) * 1996-07-16 1999-05-06 Gist-Brocades B.V. Organische lösungsmittelfreie beta-lactam enthaltende granulate
US6080427A (en) * 1997-04-17 2000-06-27 Bristol-Myers Squibb Company Cefadroxil monohydrate tablet formulation
EP1058538B9 (de) * 1998-03-06 2013-01-02 Aptalis Pharma S.r.l. Schnell zerfallende tablette
US7399751B2 (en) * 1999-11-04 2008-07-15 Sertoli Technologies, Inc. Production of a biological factor and creation of an immunologically privileged environment using genetically altered Sertoli cells
DE19922537A1 (de) * 1999-05-10 2000-11-16 Roland Bodmeier Darreichungsform zur Applikation in Körperöffnungen
WO2002024230A1 (en) * 2000-09-22 2002-03-28 Takeda Chemical Industries, Ltd. Solid preparations
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
CA2437375A1 (en) * 2001-02-05 2002-08-15 R.P. Scherer Technologies, Inc. Methods and compositions for reducing the taste of pharmaceutically active agents
RU2190403C1 (ru) * 2001-09-27 2002-10-10 Нестерук Владимир Викторович Фармацевтическая композиция, обладающая антибактериальным действием, и способ ее получения
MXPA04008720A (es) * 2002-03-12 2004-12-06 Squibb Bristol Myers Co Suspension oral de sabor agradable y metodo.
CA2500712C (en) * 2002-10-02 2011-08-09 Meiji Seika Kaisha, Ltd. Antibiotic pharmaceutical composition with improved oral absorbability
EP1578422B1 (de) * 2002-12-20 2007-04-11 NicoNovum AB Chemisch und physikalisch stabiles teilchenförmiges material enthaltend nikotin und microcrystalline cellulose
EP1648380B1 (de) * 2003-07-03 2015-04-08 Sertoli Technologies, LLC Zusammensetzungen mit sertoli-zellen und myoid-zellen und ihre verwendung in zellulären transplanten
WO2005021056A1 (en) * 2003-08-21 2005-03-10 Cns, Inc. Effervescent delivery system
AU2006318815B2 (en) 2005-11-17 2010-08-19 Novartis Ag Pharmaceutical composition
US9402809B2 (en) 2006-03-16 2016-08-02 Niconovum Usa, Inc. Snuff composition
US8617597B2 (en) 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
JP2010500871A (ja) * 2006-07-28 2010-01-14 セルトセル・バイオテクノロジー・（ユーエス）・コーポレイション 成熟セルトリ細胞およびその使用
US8833378B2 (en) * 2008-09-17 2014-09-16 Niconovum Ab Process for preparing snuff composition
AU2009333303A1 (en) * 2008-12-17 2011-08-11 Altheus Therapeutics, Inc. Enema formulations
WO2023204773A1 (en) * 2022-04-20 2023-10-26 Bilim Ilac Sanayii Ve Ticaret A.S. Tablet formulations for the treatment of urinary system infections and method for the preparation of such formulations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3344030A (en) * 1964-06-15 1967-09-26 American Home Prod Reinforced directly compressed nongranulated pharmaceutical crystalline lactose tables
DE2251250C3 (de) * 1972-10-19 1981-06-25 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung hochdosierter Antibiotica-Tabletten
DE2251249A1 (de) * 1972-10-19 1974-05-02 Hoechst Ag Verfahren zur herstellung von penicillin-verbindungen enthaltenden tabletten
ES2061623T3 (es) * 1987-03-02 1994-12-16 Brocades Pharma Bv Procedimiento para la obtencion de una composicion farmaceutica y un granulado farmaceutico.
US5049394A (en) * 1987-09-11 1991-09-17 E. R. Squibb & Sons, Inc. Pharmaceutical composition containing high drug load and method for preparing same
ES2060737T3 (es) * 1988-02-25 1994-12-01 Yamanouchi Europ Bv Procedimiento de preparacion de un granulado farmaceutico.
US5643591A (en) * 1991-01-16 1997-07-01 Fmc Corporation Solid dosage forms
AU715177B2 (en) * 1994-04-13 2000-01-20 Research Corporation Technologies, Inc. Methods of treating disease using sertoli cells and allografts or xenografts
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin

Also Published As

Publication number Publication date
NO973646D0 (no) 1997-08-07
CN1125636C (zh) 2003-10-29
HUP9801677A3 (en) 1999-05-28
ATE216576T1 (de) 2002-05-15
ES2175073T3 (es) 2002-11-16
EP0801559B1 (de) 2002-04-24
EA199900205A1 (ru) 2000-06-26
US5948422A (en) 1999-09-07
PL321567A1 (en) 1997-12-08
EP0801559A1 (de) 1997-10-22
NO319993B1 (no) 2005-10-10
PL186386B1 (pl) 2004-01-30
EA003736B1 (ru) 2003-08-28
PT801559E (pt) 2002-09-30
MX9706062A (es) 1997-10-31
EA199700093A1 (ru) 1998-02-26
AU4789696A (en) 1996-08-27
CZ230297A3 (en) 1997-11-12
DE69620866D1 (de) 2002-05-29
DE69620866T2 (de) 2003-02-27
CZ293718B6 (cs) 2004-07-14
EA000361B1 (ru) 1999-06-24
HUP9801677A2 (hu) 1998-11-30
ZA961018B (en) 1997-08-08
CN1173816A (zh) 1998-02-18
BG101822A (en) 1998-04-30
BG63528B1 (bg) 2002-04-30
WO1996024337A1 (en) 1996-08-15
BR9607189A (pt) 1997-11-11
HU227938B1 (en) 2012-06-28
NO973646L (no) 1997-09-11

Similar Documents

Publication Publication Date Title
NO973646L (no) Orale doseringsformer inneholdende et <beta>-laktam antibiotikum
ATE244004T1 (de) Pharmazeutische zubereitung enthaltend metformin und verfahren zu deren herstellung
MY116124A (en) Granulate for the preparation of fast-disintegrating and fast-dissolving compositions containing a high amount of drug
SE9502244D0 (sv) A composition and a process for the preparation thereof
NO971986L (no) Fremgangsmåte for fremstilling av små partikler
MX9603520A (es) Derivados del acido hidroxamico y acido carboxilico, procesos para su preparacion y su uso.
ES2132415T3 (es) Nuevos derivados de 5-pirrolil-2-piridilmetilsulfinilbencimidazol.
ES2170258T3 (es) Composiciones farmaceuticas con resina de intercambio ionico.
IL115920A0 (en) 2,2-dichloroalkanecarboxylic acids process of their production and pharmaceutical agents containing these
BR9609964A (pt) Formulação sólida estável de sal de enalaprila e processo para preparação da mesma
ATE342049T1 (de) Mikroverkapselte und mit gesteurter freigabe kräuter formulierungen
HUP9601321A3 (en) Substituted (benzyloxy)-carbonyl-guanidine derivatives, process for producing them, pharmaceutical compositions containing them their use as pharmaceutical compositions or diagnostica, and the use of the said compds.
HUP9901260A3 (en) Optically active phenylpyrimidine derivative as analgesic agent, process for producing it, pharmaceutical composition containing it and its intermediate
TNSN00105A1 (fr) Derives de 1-trifluoromethyl-4-hydroxy-7-piperidinyl- aminomethylchromane, procede pour leur preparation et compositions pharmaceutiques les contenant
ATE106014T1 (de) Spiramycin enthaltende arzneimittel und verfahren zu deren herstellung.
IL117083A (en) Pyridine and pyridazine derivatives processes for the production thereof and pharmaceutical compositions containing these compounds
TW334424B (en) L-arginine aldehyde derivatives process for preparing them and pharmaceutical composition
IL117734A0 (en) Beta-carbolines and pharmaceutical compositions containing them