DK0806957T3 - Kombinationsterapi mod HIV-infektion med anvendelse af HIV-proteaseinhibitoren, indinavir og omvendt transkriptaseinhibitoren, 3TC eventuelt sammen med AZT - Google Patents

Kombinationsterapi mod HIV-infektion med anvendelse af HIV-proteaseinhibitoren, indinavir og omvendt transkriptaseinhibitoren, 3TC eventuelt sammen med AZT

Info

Publication number: DK0806957T3
Authority: DK; Denmark
Prior art keywords: indinavir; azt; inhibitor; reverse transcriptase; combination therapy
Prior art date: 1995-02-01

Application number

DK96903770T

Other languages

Danish (da)

English (en)

Inventor

Emilio A Emini

Jeffrey A Chodakewitz

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-01

Filing date

1996-01-29

Publication date

2003-09-29

1996-01-29 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

2003-09-29 Application granted granted Critical

2003-09-29 Publication of DK0806957T3 publication Critical patent/DK0806957T3/da

Links

208000031886 HIV Infections Diseases 0.000 title 1
208000037357 HIV infectious disease Diseases 0.000 title 1
229940122440 HIV protease inhibitor Drugs 0.000 title 1
238000002648 combination therapy Methods 0.000 title 1
239000004030 hiv protease inhibitor Substances 0.000 title 1
208000033519 human immunodeficiency virus infectious disease Diseases 0.000 title 1
229960001936 indinavir Drugs 0.000 title 1
CBVCZFGXHXORBI-PXQQMZJSSA-N indinavir Chemical compound C([C@H](N(CC1)C[C@@H](O)C[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H]2C3=CC=CC=C3C[C@H]2O)C(=O)NC(C)(C)C)N1CC1=CC=CN=C1 CBVCZFGXHXORBI-PXQQMZJSSA-N 0.000 title 1
239000003419 rna directed dna polymerase inhibitor Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Plant Substances (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK96903770T 1995-02-01 1996-01-29 Kombinationsterapi mod HIV-infektion med anvendelse af HIV-proteaseinhibitoren, indinavir og omvendt transkriptaseinhibitoren, 3TC eventuelt sammen med AZT DK0806957T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/382,113 US6689761B1 (en)	1995-02-01	1995-02-01	Combination therapy for HIV infection
PCT/US1996/001417 WO1996023509A1 (en)	1995-02-01	1996-01-29	Combination therapy for hiv infection using the hiv protease inhibitor indinavir and the reverse transcriptase inhibitor 3tc, optionally together with azt, ddi or ddc

Publications (1)

Publication Number	Publication Date
DK0806957T3 true DK0806957T3 (da)	2003-09-29

Family

ID=23507574

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96903770T DK0806957T3 (da)	1995-02-01	1996-01-29	Kombinationsterapi mod HIV-infektion med anvendelse af HIV-proteaseinhibitoren, indinavir og omvendt transkriptaseinhibitoren, 3TC eventuelt sammen med AZT

Country Status (37)

Country	Link
US (1)	US6689761B1 (de)
EP (1)	EP0806957B1 (de)
JP (1)	JPH10513186A (de)
KR (1)	KR19980701856A (de)
CN (1)	CN1160081C (de)
AR (1)	AR002957A1 (de)
AT (1)	ATE243519T1 (de)
AU (1)	AU711176B2 (de)
BR (1)	BR9607714A (de)
CA (1)	CA2211973A1 (de)
CO (1)	CO4700430A1 (de)
CZ (1)	CZ244497A3 (de)
DE (1)	DE69628819T2 (de)
DK (1)	DK0806957T3 (de)
DZ (1)	DZ1988A1 (de)
EA (1)	EA000437B1 (de)
EE (1)	EE03514B1 (de)
ES (1)	ES2200052T3 (de)
FI (1)	FI973184L (de)
HR (1)	HRP960045B1 (de)
HU (1)	HUP9800810A3 (de)
IL (1)	IL116925A (de)
IS (1)	IS1970B (de)
MX (1)	MX9705916A (de)
MY (1)	MY121604A (de)
NO (1)	NO314568B1 (de)
NZ (1)	NZ302153A (de)
PE (1)	PE38397A1 (de)
PL (1)	PL182742B1 (de)
PT (1)	PT806957E (de)
SA (1)	SA96160669B1 (de)
SK (1)	SK103797A3 (de)
TR (1)	TR199700735T1 (de)
TW (1)	TW442291B (de)
WO (1)	WO1996023509A1 (de)
YU (1)	YU49417B (de)
ZA (1)	ZA96722B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0942747A1 (de) *	1996-08-26	1999-09-22	Chiron Corporation	Impfungstherapie nach einer hiv-infektion
AU6761198A (en) *	1998-03-17	1999-10-11	Julianna Lisziwiewicz	Anti-hiv combination comprising hydroxyurea, ddi, and a protease inhibitor
US6875773B1 (en)	1998-05-29	2005-04-05	Ben M. Dunn	Combination therapy for treatment of FIV infection
CA2374198A1 (en) *	1998-05-29	1999-12-02	Maki Arai	Combination therapy for treatment of fiv infection
EP1980617A1 (de)	1998-12-31	2008-10-15	Novartis Vaccines and Diagnostics, Inc.	Verbesserte Expression von HIV-Polypeptiden und Herstellung virusähnlicher Partikel
WO2000039304A2 (en)	1998-12-31	2000-07-06	Chiron Corporation	Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
CA2452015C (en)	2001-07-05	2012-07-03	Chiron Corporation	Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
US20030170614A1 (en)	2001-08-31	2003-09-11	Megede Jan Zur	Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
CA2583195A1 (en) *	2004-11-19	2006-05-26	Boehringer Ingelheim International Gmbh	Method for treating hiv infection through co-administration of tipranavir and reverset
WO2007012177A1 (en) *	2005-07-27	2007-02-01	Emil Toma	Zalcitabine (ddc) boosted lamivudine (3tc) compositions for antiretroviral therapy
WO2018128993A1 (en) *	2017-01-04	2018-07-12	Oyagen, Inc.	Compounds, compositions, and methods for treating human immunodeficiency virus

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4724232A (en) *	1985-03-16	1988-02-09	Burroughs Wellcome Co.	Treatment of human viral infections
US5254539A (en) *	1985-08-26	1993-10-19	U.S. Government, Dept. Of Health And Human Services, C/O National Institutes Of Health	Method of treating HIV with 2',3'-dideoxyinosine
US5028595A (en) *	1987-09-18	1991-07-02	Hoffmann-La Roche Inc.	Method for preventing AIDS in a subject or treating a subject infected with the AIDS virus
US5204466A (en)	1990-02-01	1993-04-20	Emory University	Method and compositions for the synthesis of bch-189 and related compounds
IL100502A (en)	1991-01-03	1995-12-08	Iaf Biochem Int	PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (-
US5413999A (en) *	1991-11-08	1995-05-09	Merck & Co., Inc.	HIV protease inhibitors useful for the treatment of AIDS
RU2139052C1 (ru)	1993-03-31	1999-10-10	Мерк Энд Ко., Инк.	Комбинация ингибитора вич-протеазы с другими антивирусными соединениями, фармацевтическая композиция на их основе и способ получения фармацевтической композиции
IL114208A0 (en)	1994-06-27	1995-10-31	Merck & Co Inc	Combinations of compounds pharmaceutical compositions containing them and their use as hiv protease inhibitors

1995
- 1995-02-01 US US08/382,113 patent/US6689761B1/en not_active Expired - Fee Related
1996
- 1996-01-26 IL IL11692596A patent/IL116925A/xx not_active IP Right Cessation
- 1996-01-29 AT AT96903770T patent/ATE243519T1/de not_active IP Right Cessation
- 1996-01-29 EE EE9700165A patent/EE03514B1/xx not_active IP Right Cessation
- 1996-01-29 HU HU9800810A patent/HUP9800810A3/hu unknown
- 1996-01-29 NZ NZ302153A patent/NZ302153A/xx unknown
- 1996-01-29 JP JP8523739A patent/JPH10513186A/ja not_active Withdrawn
- 1996-01-29 EP EP96903770A patent/EP0806957B1/de not_active Expired - Lifetime
- 1996-01-29 SK SK1037-97A patent/SK103797A3/sk unknown
- 1996-01-29 DK DK96903770T patent/DK0806957T3/da active
- 1996-01-29 EA EA199700150A patent/EA000437B1/ru not_active IP Right Cessation
- 1996-01-29 DE DE69628819T patent/DE69628819T2/de not_active Expired - Fee Related
- 1996-01-29 PT PT96903770T patent/PT806957E/pt unknown
- 1996-01-29 MX MX9705916A patent/MX9705916A/es not_active IP Right Cessation
- 1996-01-29 WO PCT/US1996/001417 patent/WO1996023509A1/en not_active Ceased
- 1996-01-29 CN CNB961929103A patent/CN1160081C/zh not_active Expired - Fee Related
- 1996-01-29 AU AU47748/96A patent/AU711176B2/en not_active Ceased
- 1996-01-29 CZ CZ972444A patent/CZ244497A3/cs unknown
- 1996-01-29 FI FI973184A patent/FI973184L/fi not_active Application Discontinuation
- 1996-01-29 ES ES96903770T patent/ES2200052T3/es not_active Expired - Lifetime
- 1996-01-29 TR TR97/00735T patent/TR199700735T1/xx unknown
- 1996-01-29 CA CA002211973A patent/CA2211973A1/en not_active Abandoned
- 1996-01-29 KR KR1019970705253A patent/KR19980701856A/ko not_active Ceased
- 1996-01-29 BR BR9607714A patent/BR9607714A/pt not_active Application Discontinuation
- 1996-01-30 HR HR960045A patent/HRP960045B1/xx not_active IP Right Cessation
- 1996-01-31 MY MYPI96000349A patent/MY121604A/en unknown
- 1996-01-31 PE PE1996000073A patent/PE38397A1/es not_active Application Discontinuation
- 1996-01-31 AR ARP960101221A patent/AR002957A1/es unknown
- 1996-01-31 DZ DZ960029A patent/DZ1988A1/fr active
- 1996-01-31 ZA ZA96722A patent/ZA96722B/xx unknown
- 1996-02-01 YU YU6396A patent/YU49417B/sh unknown
- 1996-02-01 CO CO96004316A patent/CO4700430A1/es unknown
- 1996-02-06 TW TW085101447A patent/TW442291B/zh not_active IP Right Cessation
- 1996-03-12 SA SA96160669A patent/SA96160669B1/ar unknown
1997
- 1997-07-29 IS IS4533A patent/IS1970B/is unknown
- 1997-07-31 NO NO19973533A patent/NO314568B1/no not_active IP Right Cessation
- 1997-09-29 PL PL96321660A patent/PL182742B1/pl unknown

Also Published As

Publication number	Publication date
CZ244497A3 (cs)	1998-01-14
PT806957E (pt)	2003-10-31
CN1160081C (zh)	2004-08-04
CA2211973A1 (en)	1996-08-08
CO4700430A1 (es)	1998-12-29
TR199700735T1 (xx)	1998-02-21
IL116925A0 (en)	1996-05-14
HUP9800810A3 (en)	2001-05-28
TW442291B (en)	2001-06-23
YU49417B (sh)	2006-01-16
EA199700150A1 (ru)	1997-12-30
MY121604A (en)	2006-02-28
IS4533A (is)	1997-07-29
PL321660A1 (en)	1997-12-22
AU711176B2 (en)	1999-10-07
IS1970B (is)	2004-12-15
KR19980701856A (ko)	1998-06-25
ZA96722B (en)	1996-08-26
PE38397A1 (es)	1997-10-09
DZ1988A1 (fr)	2002-07-20
EE03514B1 (et)	2001-10-15
FI973184A7 (fi)	1997-09-30
FI973184A0 (fi)	1997-07-31
BR9607714A (pt)	1998-01-13
NO973533D0 (no)	1997-07-31
PL182742B1 (pl)	2002-02-28
NZ302153A (en)	1998-12-23
CN1179722A (zh)	1998-04-22
DE69628819T2 (de)	2004-05-13
AU4774896A (en)	1996-08-21
ES2200052T3 (es)	2004-03-01
HK1004659A1 (en)	1998-12-04
EP0806957A1 (de)	1997-11-19
EP0806957B1 (de)	2003-06-25
EE9700165A (et)	1998-02-16
HRP960045A2 (en)	1997-10-31
US6689761B1 (en)	2004-02-10
WO1996023509A1 (en)	1996-08-08
MX9705916A (es)	1997-10-31
SA96160669B1 (ar)	2006-07-30
ATE243519T1 (de)	2003-07-15
EA000437B1 (ru)	1999-08-26
HUP9800810A2 (hu)	1998-07-28
FI973184L (fi)	1997-09-30
IL116925A (en)	2000-07-26
NO314568B1 (no)	2003-04-14
JPH10513186A (ja)	1998-12-15
HRP960045B1 (en)	2004-06-30
NO973533L (no)	1997-10-01
SK103797A3 (en)	1998-02-04
YU6396A (sh)	1999-06-15
DE69628819D1 (de)	2003-07-31
AR002957A1 (es)	1998-05-27

Publication	Publication Date	Title
FI953954A0 (fi)	1995-08-23	HIV:n käänteistranskriptaasin inhibiittoreita
FI893962A7 (fi)	1990-02-25	HIV-proteaasi-inhibiittoreita, jotka ovat hyödyllisiä AIDS:in hoidossa
TR199800117A3 (tr)	1998-08-21	Isaksazol- ve krotonasitamid türevleri ve bunlarin kullanimi.
FI911528A0 (fi)	1991-03-28	Mot non-a, non-b-hepatisvirus riktade, med antikroppar immunokemiskt reaktiva peptider.
FI973184L (fi)	1997-09-30	Kombinaatioterapia HIV-infektiota varten käyttäen HIV-proteaasi-inhibiittoria indinavir ja käänteistranskriptaasi-inhibiittoria 3TC, mahdollisesti yhdessä AZT:n, DDI:n tai DDC:n kanssa
FI912926A7 (fi)	1991-12-19	HIV-käänteistranskriptaasin inhibiittoreita
DK0522059T3 (da)	1995-04-18	Fastholdelsesindretning og forbindelsesindretning, som indbefatter fastholdelsesindretningen
FI884669A0 (fi)	1988-10-11	Maraging-staol.
NO900033L (no)	1991-07-08	Laasebolt og roerklammer.
IT8921832A0 (it)	1989-09-26	Rubinetto inviolabile.
NO910590D0 (no)	1991-02-14	Hydratiserte silikater, fremgangsmaate for deres fremstilling og anvendelse.
NO901758L (no)	1990-10-23	Reninhemmende dipeptider, fremgangsmaate for deres fremstilling, midler som inneholder disse og deres anvendelse.
ES1033258Y (es)	1997-01-16	Collarin bisagra perfeccionado.
FR2708445B1 (fr)	1995-09-01	Cuillère à diffuseur à usage unique.
ES1027737Y (es)	1995-03-01	Canutillo perfeccionado.
FR2710832B1 (fr)	1995-12-22	Articulateur dentaire.
ES1028704Y (es)	1995-10-01	Conmutador dos entradas una salida.
GB9520721D0 (en)	1995-12-13	HIV reverse transcriptase inhibitors
KR950031759U (ko)	1995-11-22	피. 시. 비 기판 고정장치
FI962173A0 (fi)	1996-05-23	Med bladskydd foersedd saogstaellning
ES1027916Y (es)	1995-04-16	Colgante perfeccionado.
ES1028505Y (es)	1995-09-01	Pulsera perfeccionada.
ES1028580Y (es)	1995-07-01	Pulsera perfeccionada.
ES1028504Y (es)	1995-09-01	Pulsera perfeccionada.
ES1027074Y (es)	1995-01-16	Pulsador perfeccionado.