DK0807431T3 - Fremgangsmåde til fremstilling af carotenoidpræparater - Google Patents

Fremgangsmåde til fremstilling af carotenoidpræparater

Info

Publication number
DK0807431T3
DK0807431T3 DK97106957T DK97106957T DK0807431T3 DK 0807431 T3 DK0807431 T3 DK 0807431T3 DK 97106957 T DK97106957 T DK 97106957T DK 97106957 T DK97106957 T DK 97106957T DK 0807431 T3 DK0807431 T3 DK 0807431T3
Authority
DK
Denmark
Prior art keywords
carotenoid
preparation
carotenoid preparations
disclosed
emulsion
Prior art date
Application number
DK97106957T
Other languages
Danish (da)
English (en)
Inventor
Leonard Joseph Scialpi
Ray Edward Kowalski
William Joseph Mergens
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Application granted granted Critical
Publication of DK0807431T3 publication Critical patent/DK0807431T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/924—Significant dispersive or manipulative operation or step in making or stabilizing colloid system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DK97106957T 1996-05-14 1997-04-26 Fremgangsmåde til fremstilling af carotenoidpræparater DK0807431T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1756896P 1996-05-14 1996-05-14

Publications (1)

Publication Number Publication Date
DK0807431T3 true DK0807431T3 (da) 2004-07-26

Family

ID=21783319

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97106957T DK0807431T3 (da) 1996-05-14 1997-04-26 Fremgangsmåde til fremstilling af carotenoidpræparater

Country Status (10)

Country Link
US (1) US6093348A (fr)
EP (1) EP0807431B1 (fr)
JP (1) JP3961070B2 (fr)
CN (1) CN1079212C (fr)
AT (1) ATE262316T1 (fr)
BR (1) BR9703134A (fr)
DE (1) DE69728206T2 (fr)
DK (1) DK0807431T3 (fr)
ES (1) ES2216079T3 (fr)
IN (1) IN183685B (fr)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2206679T5 (es) * 1996-01-22 2011-10-27 Chr. Hansen A/S Composiciones dispersables en agua que contienen un pigmento natural hidrofóbico, su procedimiento de preparación y su utilización.
IL143197A0 (en) 1998-11-20 2002-04-21 Rtp Pharma Inc Dispersible phospholipid stabilized microparticles
EP1276465B1 (fr) * 2000-04-20 2014-03-12 Jagotec AG Procede ameliore destine aux particules de medicament insolubles dans l'eau
US20030104090A1 (en) * 2000-05-05 2003-06-05 Levy Pedro E. Supplements containing annatto extracts and carotenoids and methods for using the same
ATE367802T1 (de) 2000-09-20 2007-08-15 Jagotec Ag Verfahren zur sprühtrocknung von zusammensetzungen enthaltend fenofibrat
DE10064387A1 (de) 2000-12-21 2002-06-27 Basf Ag Verfahren zur Herstellung von Trockenpulvern eines oder mehrerer Sauerstoff-haltiger Carotinoide
WO2002077105A1 (fr) * 2001-03-22 2002-10-03 Fuji Chemical Industry Co., Ltd. Compositions pulverulentes a base d'astaxanthine et procede de production associe
US6811801B2 (en) * 2001-12-12 2004-11-02 Abbott Laboratories Methods and compositions for brightening the color of thermally processed nutritionals
EP1519714B1 (fr) 2002-06-28 2010-10-20 Protiva Biotherapeutics Inc. Appareil liposomal et procedes de fabrication
US20050148517A1 (en) * 2002-07-29 2005-07-07 Lockwood Samuel F. Carotenoid ether analogs or derivatives for controlling connexin 43 expression
US7320997B2 (en) * 2002-07-29 2008-01-22 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease
US7763649B2 (en) 2002-07-29 2010-07-27 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for controlling connexin 43 expression
CN101845009B (zh) 2002-07-29 2012-10-03 卡达克斯药物公司 用于抑制和改善疾病的类胡萝卜素结构类似物
US20050004235A1 (en) * 2002-07-29 2005-01-06 Lockwood Samuel Fournier Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease
US20050059635A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid ester analogs or derivatives for controlling C-reactive protein levels
US7375133B2 (en) * 2002-07-29 2008-05-20 Cardax Pharmaceuticals, Inc. Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US20050143475A1 (en) * 2002-07-29 2005-06-30 Lockwood Samuel F. Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury
US20050026874A1 (en) * 2002-07-29 2005-02-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease
US7723327B2 (en) 2002-07-29 2010-05-25 Cardax Pharmaceuticals, Inc. Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease
US7521584B2 (en) * 2002-07-29 2009-04-21 Cardax Pharmaceuticals, Inc. Carotenoid analogs or derivatives for the inhibition and amelioration of disease
US20050049248A1 (en) * 2002-07-29 2005-03-03 Lockwood Samuel Fournier Carotenoid ether analogs or derivatives for controlling C-reactive protein levels
US7345091B2 (en) * 2002-07-29 2008-03-18 Cardax Pharmaceuticals, Inc. Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
US20050059659A1 (en) * 2002-07-29 2005-03-17 Lockwood Samuel Fournier Carotenoid analogs or derivatives for controlling C-reactive protein levels
JP4773337B2 (ja) 2003-03-27 2011-09-14 ディーエスエム アイピー アセッツ ビー．ブイ． ビーズレットの製造方法
US7110827B2 (en) * 2003-04-25 2006-09-19 Medtronic, Inc. Electrical connectors for medical lead having weld-less wiring connection
US7332178B2 (en) 2003-04-25 2008-02-19 Abbott Laboratories Stable nutritional powder containing ascorbyl palmitate
US9247765B2 (en) * 2004-01-14 2016-02-02 Omniactive Health Technologies Limited Stable beadlets of lipophilic nutrients
US20060058269A1 (en) * 2004-04-14 2006-03-16 Lockwood Samuel F Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation
CA2564066A1 (fr) * 2004-04-14 2005-11-03 Hawaii Biotech, Inc. Analogues ou derives de carotenoide pour inhiber et reduire l'inflammation
JP4562174B2 (ja) * 2004-08-23 2010-10-13 カゴメ株式会社 カロテノイド含有物の製造方法
WO2006024620A1 (fr) * 2004-08-31 2006-03-09 Akzo Nobel N.V. Procede de solubilisation de pigments, composition de pigments et utilisation de celle-ci
US10463061B2 (en) * 2004-11-19 2019-11-05 Dsm Ip Assets B.V. Modified plant gums for preparations of active ingredients
US8755258B2 (en) 2005-02-16 2014-06-17 Mitsubishi Electric Corporation Optical disc and optical disc device
CN100421650C (zh) * 2005-03-23 2008-10-01 浙江新和成股份有限公司 水分散性类胡萝卜素粉的制备方法
CN101267805A (zh) * 2005-07-27 2008-09-17 普洛体维生物治疗公司 制造脂质体的系统和方法
RU2008110066A (ru) * 2005-08-15 2009-09-27 Форес Фармасьютикал Рисерч Н.В. (Nl) Кристалические формы астаксантина
US7435846B2 (en) * 2006-08-18 2008-10-14 Industrial Organica, S.A. De C.V. Absorption and bioavailability of carotenoids, formulations and applications
WO2008110626A1 (fr) * 2007-03-15 2008-09-18 Dsm Ip Assets B.V. Particules micronisées stabilisées
WO2009093595A1 (fr) * 2008-01-25 2009-07-30 Fujifilm Corporation Procédé de production d'une composition d'émulsion contenant des caroténoïdes, composition d'émulsion contenant des caroténoïdes obtenue par le procédé, composition en poudre contenant des caroténoïdes, et préparations cosmétique et alimentaire fonctionnelles contenant chacune la composition
EP2210593A3 (fr) 2009-01-21 2011-05-18 DSM IP Assets B.V. Formulations de vitamine A et dérivés correspondants pouvant être mis en comprimés
EP2411137B1 (fr) 2009-03-27 2016-09-07 Bend Research, Inc. Procédé de séchage par pulvérisation
EP2478768A4 (fr) * 2009-09-14 2014-05-07 Univ Hokkaido Nat Univ Corp Agent antiphytoviral
CN102933098B (zh) 2010-06-08 2017-03-29 三荣源有限公司 防止类胡萝卜色素附着于容器的方法
JP5600513B2 (ja) * 2010-07-29 2014-10-01 理研ビタミン株式会社 クロセチン製剤の製造方法
EP2611529B1 (fr) 2010-09-03 2019-01-23 Bend Research, Inc. Procedede de séchage par pulvérisation
WO2012031133A2 (fr) 2010-09-03 2012-03-08 Bench Research, Inc. Appareil de séchage par atomisation et procédés d'utilisation de cet appareil
WO2012040502A1 (fr) 2010-09-24 2012-03-29 Bend Research, Inc. Procédé et appareil de séchage par pulvérisation à température élevée
WO2012069322A1 (fr) 2010-11-26 2012-05-31 Dsm Ip Assets B.V. Hydrocolloïde protecteur pour principes actifs
US20120157547A1 (en) 2010-12-21 2012-06-21 Ricardo Montoya-Olvera Compositions and applications of carotenoids of improved absorption and bioavailability
BR112015008539B1 (pt) * 2012-10-18 2020-11-03 Dsm Ip Assets B.V. microesferas compreendendo carotenoides, processo para produção das referidas microesferas e produtos alimentícios, rações e de cuidados pessoais
WO2015044222A1 (fr) * 2013-09-24 2015-04-02 Dsm Ip Assets B.V. Formulations stables pour colorer des boissons et des produits alimentaires
WO2016067132A1 (fr) 2014-10-31 2016-05-06 Bend Research Inc. Procédé de formation de domaines actifs dispersés dans une matrice
JP6938824B2 (ja) * 2016-03-15 2021-09-22 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． 被覆された粒子
ES2969807T3 (es) * 2016-03-24 2024-05-22 Basf Se Preparados de principios activos de múltiples fases
WO2017168006A1 (fr) * 2016-04-01 2017-10-05 Dsm Ip Assets B.V. Boissons comprenant des granules stables de lutéine broyée
WO2018015346A1 (fr) * 2016-07-19 2018-01-25 Basf Se Préparations vitaminiques contenant du gallate de propyle
US12491261B2 (en) 2016-10-26 2025-12-09 Acuitas Therapeutics, Inc. Lipid nanoparticle formulations
US11197493B2 (en) * 2017-09-12 2021-12-14 Omniactive Health Technologies Limited Stabilized fat soluble nutrient compositions and process for the preparation thereof
JP7225820B2 (ja) 2019-01-21 2023-02-21 株式会社アイシン 車両用開閉体制御装置
EP3982935A1 (fr) * 2019-06-17 2022-04-20 DSM IP Assets B.V. Composition comprenant du chlorhydrate de metformine, de la vitamine b12, et au moins un additif d'écoulement
EP3982936A1 (fr) * 2019-06-17 2022-04-20 DSM IP Assets B.V. Forme posologique pharmaceutique solide comprenant de la vitamine b12 séchée par pulvérisation
WO2020254404A1 (fr) * 2019-06-17 2020-12-24 Dsm Ip Assets B.V. Forme posologique pharmaceutique comprenant de la metformine et du citrate de calcium
CN112438950A (zh) * 2019-08-16 2021-03-05 北京化工大学 一种β-胡萝卜素透明水分散液及其制备方法
CN111471317B (zh) * 2020-03-26 2021-06-04 广东省农业科学院蚕业与农产品加工研究所 一种稳态化玉米黄色素及其制备方法
CN111838648B (zh) * 2020-06-16 2023-04-25 嘉必优生物技术（武汉）股份有限公司 一种生产纳米级类胡萝卜素乳液的装置及方法
ES3054438T3 (en) 2020-07-16 2026-02-03 Acuitas Therapeutics Inc Cationic lipids for use in lipid nanoparticles
CN112841645A (zh) * 2021-01-14 2021-05-28 江南大学 一种β-胡萝卜素微胶囊的制备方法
CN113426355A (zh) * 2021-06-25 2021-09-24 骏马化纤股份有限公司 一种化纤生产用油剂乳液自动化控制系统及制备方法
CA3242402A1 (fr) 2021-12-16 2023-06-22 Acuitas Therapeutics, Inc. Lipides destines a etre utilises dans des formulations de nanoparticules lipidiques
CN118525919A (zh) * 2023-02-22 2024-08-23 浙江可明生物医药有限公司 类胡萝卜素制剂的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2756177A (en) * 1953-03-09 1956-07-24 Hoffmann La Roche Process for making fat-soluble vitamin active powder
US2861891A (en) * 1956-12-13 1958-11-25 Hoffmann La Roche Water dispersible carotenoid compositions and process of making the same
DE1211911B (de) * 1959-09-08 1966-03-03 Hoffmann La Roche Verfahren zur Herstellung eines insbesondere zum Faerben von Lebens- und Futtermitteln geeigneten Carotinoidpraeparates
US3998753A (en) * 1974-08-13 1976-12-21 Hoffmann-La Roche Inc. Water dispersible carotenoid preparations and processes thereof
DE3048000A1 (de) * 1980-12-19 1982-07-15 Basf Ag Stabile injizierbare (beta)-carotin-solubilisate und verfahren zu ihrer herstellung
US4533254A (en) * 1981-04-17 1985-08-06 Biotechnology Development Corporation Apparatus for forming emulsions
US4908154A (en) * 1981-04-17 1990-03-13 Biotechnology Development Corporation Method of forming a microemulsion
DE3119383A1 (de) * 1981-05-15 1982-12-02 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von feinverteilten, pulverfoermigen carotinodpraeparaten
SE8604117D0 (sv) * 1986-09-29 1986-09-29 Kabivitrum Ab Composition
DE3702031A1 (de) * 1987-01-24 1988-08-04 Basf Ag Verfahren zur herstellung von mikrodispersen fischoelpraeparaten
ATE96312T1 (de) * 1989-07-25 1993-11-15 Hoffmann La Roche Verfahren zur herstellung von carotinoidpraeparaten.
DK546289D0 (da) * 1989-11-02 1989-11-02 Danochemo As Carotenoidpulvere
DK19393D0 (da) * 1993-02-19 1993-02-19 Danochemo As Fremgangsmaade til fremstilling af et i vand dispergerbart pulverformigt carotenoidpraeparat
DE4329446A1 (de) * 1993-09-01 1995-03-02 Basf Ag Verfahren zur Herstellung von feinteiligen Farb- oder Wirkstoffzubereitungen
DE19649062A1 (de) * 1996-11-27 1998-05-28 Basf Ag Flüssige, mit Öl mischbare Carotinoid-Zubereitungen

Also Published As

Publication number Publication date
DE69728206D1 (de) 2004-04-29
IN183685B (fr) 2000-03-18
DE69728206T2 (de) 2005-03-10
CN1079212C (zh) 2002-02-20
EP0807431A3 (fr) 1998-08-12
EP0807431B1 (fr) 2004-03-24
JP3961070B2 (ja) 2007-08-15
EP0807431A2 (fr) 1997-11-19
CN1176760A (zh) 1998-03-25
ES2216079T3 (es) 2004-10-16
ATE262316T1 (de) 2004-04-15
JPH1046041A (ja) 1998-02-17
BR9703134A (pt) 1998-08-18
US6093348A (en) 2000-07-25

Similar Documents

Publication Publication Date Title
DK0807431T3 (da) Fremgangsmåde til fremstilling af carotenoidpræparater
DK0805822T4 (da) Spraytørret erythropoietin
HUT54895A (en) Process for producing stabilized fgf composition
DE69717263D1 (de) Zubereitung mit verzögerter freisetzung und deren herstellung
AU2741295A (en) Method for preparing an influenza virus, antigens obtained and applications thereof
ES2066491T3 (es) Composiciones de colorantes en polvo y procedimiento para su preparacion.
NO974768D0 (no) Fremgangsmåte for fremstilling av et forbedret lavtstövende, lettflytende pigment
HU9204034D0 (en) Dialkoxi-pyridinyl-benzimidazole derivatives, method for producing them and their pharmaceutical application
EP0837139A3 (fr) Conversion en deux étapes de conjugués d'isoflavones à partir de protéines végétales en aglucones isoflavones
AU2808295A (en) Aqueous fluoropolymer emulsion and process for producing the same
EP0755440A4 (fr) Nouveaux virus mutes, composes antiviraux et nouveaux procedes de production de vaccins
BR9000736A (pt) Processo para preparar uma composicao aquosa para xampu
ES2196743T3 (es) Sorbitol en polvo y su procedimiento de preparacion.
DK559887A (da) Fremgangsmaade til fremstilling af carbinolderivater
CA2085114A1 (fr) Methode de preparation de materiaux de polytetrafluoroethylene poreux colores
DE69503097D1 (de) Veresterungsverfahren eines oligomeren polyphenolischen Extraktes pflanzlicher Herkunft, die so erhaltene Zusammensetzung und ihre Anwendung
DE3760617D1 (en) Aliphatic aldehydes, method for their production and their application as perfume agents
GB2363360B (en) A method of shaping heat-shrinkable materials
HU186343B (en) Pungicide preparations containing 2,3,6-trisubsituted-n-acyl-anilide derivatives as actor as well as method for producing the actors
NL7904076A (nl) Nieuwe ionogene polyjoodbenzeenderivaten, alsmede voor radiografische doeleinden geschikte preparaten.
DE3881326D1 (de) Verfahren zur herstellung von paramunitaetsinducern.
NO963003L (no) Fremgangsmåte for fremstilling av en vandig emulsjon med snever dråpestörrelsesfordeling, og anvendelse av en slik emulsjon for fremstilling av en polymerdispersjon
AU5266790A (en) Hydraulic substance, method of producing and curing the same, curing chamber, and paint
FI930581L (fi) Foerfarande foer framstaellning av mikrosfaerhaltiga vaermehaerdande hartskompositioner
GB8717418D0 (en) Joining of pipes