DK0807439T3 - Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne - Google Patents

Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne

Info

Publication number
DK0807439T3
DK0807439T3 DK97303204T DK97303204T DK0807439T3 DK 0807439 T3 DK0807439 T3 DK 0807439T3 DK 97303204 T DK97303204 T DK 97303204T DK 97303204 T DK97303204 T DK 97303204T DK 0807439 T3 DK0807439 T3 DK 0807439T3
Authority
DK
Denmark
Prior art keywords
adults
treatment
respiratory distress
distress syndrome
human chemokine
Prior art date
Application number
DK97303204T
Other languages
English (en)
Inventor
John Richard White
Louis Martin Pelus
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of DK0807439T3 publication Critical patent/DK0807439T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/195—Chemokines, e.g. RANTES
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DK97303204T 1996-05-14 1997-05-12 Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne DK0807439T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1787196P 1996-05-14 1996-05-14

Publications (1)

Publication Number Publication Date
DK0807439T3 true DK0807439T3 (da) 2003-08-11

Family

ID=21785003

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97303204T DK0807439T3 (da) 1996-05-14 1997-05-12 Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne

Country Status (5)

Country Link
US (5) US6290948B1 (da)
EP (1) EP0807439B1 (da)
JP (2) JPH1053533A (da)
DE (1) DE69721120T2 (da)
DK (1) DK0807439T3 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6811773B1 (en) 1993-12-22 2004-11-02 Human Genome Sciences, Inc. Human monocyte colony inhibitory factor (M-CIF) polypeptides
US6451562B1 (en) 1993-12-22 2002-09-17 Human Genome Sciences, Inc. Polypeptides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) polynucleotides
US6488925B2 (en) 1993-12-22 2002-12-03 Human Genome Sciences, Inc. Macrophage inflammatory protein-4 (MIP-4) polypeptides
US6495129B1 (en) 1994-03-08 2002-12-17 Human Genome Sciences, Inc. Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3)
EA199800352A1 (ru) * 1995-09-29 1998-12-24 Смитклайн Бичам Корпорейшн ПОЛИПЕПТИД ХЕМОКИНА β-8 (ВАРИАНТЫ) И СПОСОБ ЕГО ПОЛУЧЕНИЯ, КОМПОЗИЦИИ ПОЛИПЕПТИДОВ, ВЕКТОР, КЛЕТКА-ХОЗЯИН, АГОНИСТ И АНТАГОНИСТ, ВСЕ - УПОМЯНУТОГО ПОЛИПЕПТИДА, И СПОСОБ ИДЕНТИФИКАЦИИ ПОСЛЕДНЕГО, СПОСОБ ЛЕЧЕНИЯ БОЛЬНОГО, ИСПЫТЫВАЮЩЕГО ПОТРЕБНОСТЬ В Хк-β-8 (ВАРИАНТЫ), СПОСОБ ЛЕЧЕНИЯ БОЛЬНОГО, ИСПЫТЫВАЮЩЕГО ПОТРЕБНОСТЬ В ПОДАВЛЕНИИ Хк-β-8, СПОСОБ ДИАГНОСТИКИ ЗАБОЛЕВАНИЯ ИЛИ ПРЕДРАСПОЛОЖЕННОСТИ К ЗАБОЛЕВАНИЮ, ОБУСЛОВЛЕННОМУ НЕДОСТАТОЧНОЙ ЭКСПРЕССИЕЙ ПОЛИПЕПТИДА
US6713052B1 (en) 1995-10-24 2004-03-30 Human Genome Sciences, Inc. Method of mobilizing stem cells with chemokine β-8
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10
US6632425B1 (en) 1997-03-20 2003-10-14 Human Genome Sciences, Inc. Chemokine compositions
US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
KR19990042713A (ko) * 1997-11-27 1999-06-15 허일섭 사람에서 분리한 c 6 베타-케모카인 lkn-1의 cdna 및 재조합 lkn-1의 제조방법
AU1824499A (en) * 1997-12-30 1999-07-19 Chiron Corporation Human cxc chemokine ((tim-1))
US6495128B1 (en) 1998-11-10 2002-12-17 Human Genome Sciences, Inc. Human chemokine β-7 deletion and substitution proteins
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
EP1348443A4 (en) * 2000-12-08 2005-07-06 Takeda Pharmaceutical COMBINED MEDICINES
WO2005025593A2 (en) * 2003-05-09 2005-03-24 Schering Aktiengesellschaft Treatment of inflammatory respiratory diseases
EP2266606B1 (en) 2003-05-15 2014-09-10 Genentech, Inc. Methods and compositions for the prevention and treatment of sepsis
AU2005313971B2 (en) * 2004-12-08 2011-10-13 Immunomedics, Inc. Methods and compositions for immunotherapy and detection of inflammatory and immune-dysregulatory disease, infectious disease, pathologic angiogenesis and cancer
EP2143436B1 (en) 2007-03-28 2015-07-29 Universidad de Barcelona Cd6 product for treatment of infectious diseases and related inflammatory processes
SG191716A1 (en) 2010-11-19 2013-08-30 Toshio Imai Neutralizing anti-ccl20 antibodies
JP2019535834A (ja) 2016-11-18 2019-12-12 ユニベルシタ デ バルセロナ 感染症及び関連炎症プロセスの処置のためのｃｄ６及びイミペネムの併用療法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4897348A (en) * 1983-08-25 1990-01-30 Sri International Recombinant materials and methods for producing human connective tissue-activating peptide-III and analogs thereof
US4897338A (en) * 1987-08-03 1990-01-30 Allied-Signal Inc. Method for the manufacture of multilayer printed circuit boards
FI903931A7 (fi) * 1988-12-08 1990-08-08 Sandoz Ag Neutrofiiliaktivoiva peptidi-2
US5179078A (en) * 1989-05-12 1993-01-12 Dana Farber Cancer Institute Method of suppressing tumor formation in vivo
US5212073A (en) * 1989-05-12 1993-05-18 Genetics Institute, Inc. Process for producing human JE cytokine
CA2064558C (en) * 1989-09-25 2001-01-30 Ian B. Pragnell Method for inhibiting growth of stem cells
NZ237202A (en) * 1990-02-23 1994-01-26 Bristol Myers Squibb Co Composition containing beta-lactam antibiotic and cationic oligopeptide
ATE177472T1 (de) * 1990-09-14 1999-03-15 Chiron Corp Expression von makrophagen-induzierbaren proteinen (mips) in hefezellen
US5401651A (en) * 1991-10-16 1995-03-28 Walz; Alfred DNA encoding ENA-78, a neutrophil activating factor
US5306709A (en) * 1991-11-15 1994-04-26 The University Of Pennsylvania Suppression of megakaryocytopoiesis by macrophage inflammatory proteins
US5413778A (en) * 1992-10-05 1995-05-09 The Regents Of The University Of Michigan Labelled monocyte chemoattractant protein material and medical uses thereof
US5346686A (en) * 1992-10-05 1994-09-13 Mallinckrodt Medical, Inc. Labelled interleukin-8 and medical uses thereof
US5474983A (en) * 1993-03-15 1995-12-12 The Research Foundation Of State University Of New York Method of inhibiting pro-inflammatory mediator release from basophils and mast cells
US5346685A (en) * 1993-04-23 1994-09-13 Mobil Oil Corp. Synthetic porous crystalline MCM-51, its synthesis and use
JPH0789866A (ja) * 1993-09-21 1995-04-04 Nippon Kayaku Co Ltd 感染防御剤
ATE262914T1 (de) * 1993-12-22 2004-04-15 Human Genome Sciences Inc Entzündungsproteine aus makrophagen mip-3, mip-4 und mip-1gamma
EP0770086A4 (en) * 1994-05-16 1998-07-15 Human Genome Sciences Inc MACROPHAGE MIGRATION INHIBITING FACTOR-3
AU708558B2 (en) * 1994-08-23 1999-08-05 Human Genome Sciences, Inc. Human chemokine beta-9
DE69433648T2 (de) * 1994-08-23 2005-02-17 Human Genome Sciences, Inc. Menschliche chemokin-polypeptide
WO1996009062A1 (en) * 1994-09-23 1996-03-28 University Of Nebraska Board Of Regents Polypeptide agonists and antagonists of human interleukin-8
US5602008A (en) * 1994-11-29 1997-02-11 Incyte Pharmaceuticals, Inc. DNA encoding a liver expressed chemokine
CN1190991A (zh) * 1995-06-05 1998-08-19 人类基因组科学公司 人类趋化因子β－11和人类趋化因子α－1
AU713267B2 (en) * 1995-06-06 1999-11-25 Human Genome Sciences, Inc. Human chemokine beta-13
AU2698795A (en) * 1995-06-06 1996-12-24 Human Genome Sciences, Inc. Human chemokine beta-12
ZA968896B (en) * 1995-10-24 1997-04-24 Smithkline Beecham Corp Method of mobilizing hematopoietic stem cells
ZA968897B (en) * 1995-10-24 1998-07-14 Smithkline Beecham Corp Novel chemokine for mobilizing stem cells
WO1997019173A1 (en) * 1995-11-21 1997-05-29 Smithkline Beecham Corporation Method of treating sepsis
WO1997031098A1 (en) * 1996-02-23 1997-08-28 Human Genome Sciences, Inc. Human chemokine polypeptides
US6509313B1 (en) * 1996-02-28 2003-01-21 Cornell Research Foundation, Inc. Stimulation of immune response with low doses of cytokines
WO1997035027A1 (en) 1996-03-18 1997-09-25 Human Genome Sciences, Inc. Chemokine alpha 3
JP2000508527A (ja) * 1996-03-27 2000-07-11 アイコス コーポレイション 単球走化性タンパク質―５物質及び方法
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10
GB9617923D0 (en) * 1996-08-28 1996-10-09 Smithkline Beecham Plc Novel receptor
AU4243097A (en) * 1996-09-10 1998-04-02 Schering Corporation Mammalian chemokines, related reagents
WO1998014573A1 (en) * 1996-09-30 1998-04-09 The General Hospital Corporation Mcp-4 and mcp-5: novel chemokines

Also Published As

Publication number Publication date
DE69721120D1 (de) 2003-05-28
JP2001122801A (ja) 2001-05-08
US20020155094A1 (en) 2002-10-24
EP0807439B1 (en) 2003-04-23
DE69721120T2 (de) 2003-12-04
US20020146390A1 (en) 2002-10-10
US6406688B1 (en) 2002-06-18
US20020141972A1 (en) 2002-10-03
EP0807439A2 (en) 1997-11-19
US6290948B1 (en) 2001-09-18
JPH1053533A (ja) 1998-02-24
EP0807439A3 (en) 1998-03-11

Similar Documents

Publication Publication Date Title
DK0807439T3 (da) Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne
DE59709609D1 (de) Patientenuntersuchungstisch
CY2007001I2 (el) Φαρμακευτικο σκευασμα για χρηση στη θεραπεια του διαβητη
EE200100480A (et) Ksenoon kasutamiseks närvimürgistuste ravis
DE69617754D1 (de) Inhalator
DE69721369D1 (de) Inhalator
DK0912194T3 (da) Polynucleotid-vaccineformulering, især til behandling af respiratorisk sygdom hos kvæg
DE69513438D1 (de) Absorbierender Wegwerfartikel
BR9506912A (pt) Artigo absorvente descartável
BR9509966A (pt) Artigo absorvente descartável
BR9503001A (pt) Artigo absorvente descartável
ITTO910327A0 (it) Membrane permselettive e loro impiego
NO971811D0 (no) Bicykliske tetrahydropyrazolopyridiner og deres anvendelse som legemidler
DE69715219D1 (de) Inhalator
DK19893D0 (da) Praeparat til nasal behandling
TR199901772T2 (da)
EE03682B1 (et) Asendatud bensimidasooli derivaadid, protsessid nende valmistamiseks ning nende kasutamine
FI956298L (fi) 3-fenyyli-isokinolin-1(2H)-oneja, niiden valmistus ja terapeuttinen käyttö
PT946175E (pt) Utilizacao de uma combinacao de inibidores de h+, k+ -atpase e de glucocorticiodes no tratamento de polipos nasais
NO991459L (no) Anvendelse av 1-hydroksy-2-pyridoner til behandling av hudinfeksjoner
PT932400E (pt) Derivados de anticonvulsionantes uteis no tratamento da dor neuropatica
IT1298689B1 (it) Dilatatore nasale perfezionato
IT233411Y1 (it) Pannolino assorbente regolabile in particolare per adulti
DE4499496T1 (de) Haltbarer Patientenstuhl
BR9604756A (pt) Banheira hospitalar