DK0807439T3 - Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne - Google Patents

Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne

Info

Publication number
DK0807439T3
DK0807439T3 DK97303204T DK97303204T DK0807439T3 DK 0807439 T3 DK0807439 T3 DK 0807439T3 DK 97303204 T DK97303204 T DK 97303204T DK 97303204 T DK97303204 T DK 97303204T DK 0807439 T3 DK0807439 T3 DK 0807439T3
Authority
DK
Denmark
Prior art keywords
adults
treatment
respiratory distress
distress syndrome
human chemokine
Prior art date
Application number
DK97303204T
Other languages
English (en)
Inventor
John Richard White
Louis Martin Pelus
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of DK0807439T3 publication Critical patent/DK0807439T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/195Chemokines, e.g. RANTES
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/17Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
DK97303204T 1996-05-14 1997-05-12 Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne DK0807439T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1787196P 1996-05-14 1996-05-14

Publications (1)

Publication Number Publication Date
DK0807439T3 true DK0807439T3 (da) 2003-08-11

Family

ID=21785003

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97303204T DK0807439T3 (da) 1996-05-14 1997-05-12 Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne

Country Status (5)

Country Link
US (5) US6290948B1 (da)
EP (1) EP0807439B1 (da)
JP (2) JPH1053533A (da)
DE (1) DE69721120T2 (da)
DK (1) DK0807439T3 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6488925B2 (en) 1993-12-22 2002-12-03 Human Genome Sciences, Inc. Macrophage inflammatory protein-4 (MIP-4) polypeptides
US6451562B1 (en) 1993-12-22 2002-09-17 Human Genome Sciences, Inc. Polypeptides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) polynucleotides
US6811773B1 (en) 1993-12-22 2004-11-02 Human Genome Sciences, Inc. Human monocyte colony inhibitory factor (M-CIF) polypeptides
US6495129B1 (en) 1994-03-08 2002-12-17 Human Genome Sciences, Inc. Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3)
AU711573B2 (en) * 1995-09-29 1999-10-14 Smithkline Beecham Corporation Short forms of chemokine beta-8
US6713052B1 (en) 1995-10-24 2004-03-30 Human Genome Sciences, Inc. Method of mobilizing stem cells with chemokine β-8
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10
US6632425B1 (en) 1997-03-20 2003-10-14 Human Genome Sciences, Inc. Chemokine compositions
US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
KR19990042713A (ko) * 1997-11-27 1999-06-15 허일섭 사람에서 분리한 c 6 베타-케모카인 lkn-1의 cdna 및 재조합 lkn-1의 제조방법
AU1824499A (en) * 1997-12-30 1999-07-19 Chiron Corporation Human cxc chemokine ((tim-1))
EP1129193A4 (en) 1998-11-10 2005-08-10 Human Genome Sciences Inc CHEMOKIN BETA-7
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
WO2002045750A1 (en) * 2000-12-08 2002-06-13 Takeda Chemical Industries, Ltd. Combination drugs
US20070141053A1 (en) * 2003-05-09 2007-06-21 Schering Aktiengesellschaft Treatment of inflammatory respiratory diseases
EP2266606B1 (en) 2003-05-15 2014-09-10 Genentech, Inc. Methods and compositions for the prevention and treatment of sepsis
EP1819731A4 (en) * 2004-12-08 2013-02-13 Immunomedics Inc METHOD AND COMPOSITION FOR IMMUNOTHERAPY AND FOR THE DETECTION OF INFLAMMATORY AND DYSEGRATIVE IMMUNE DISEASES, INFECTION DISEASES, PATHOLOGICAL ANGIOGENESIS AND CANCER
EP2143436B1 (en) * 2007-03-28 2015-07-29 Universidad de Barcelona Cd6 product for treatment of infectious diseases and related inflammatory processes
KR101919170B1 (ko) 2010-11-19 2018-11-15 에자이 알앤드디 매니지먼트 가부시키가이샤 중화 항-ccl20 항체
CA3044334A1 (en) 2016-11-18 2018-05-24 Institut D'investigacions Biomediques August Pi I Sunyer- Idibaps Combined cd6 and imipenem therapy for treatment of infectious diseases and related inflammatory processes

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4897348A (en) * 1983-08-25 1990-01-30 Sri International Recombinant materials and methods for producing human connective tissue-activating peptide-III and analogs thereof
US4897338A (en) * 1987-08-03 1990-01-30 Allied-Signal Inc. Method for the manufacture of multilayer printed circuit boards
KR910700260A (ko) * 1988-12-08 1991-03-14 예안 크라메트, 한스 루돌프 하우스 호중구-활성화 펩티드-2
US5179078A (en) * 1989-05-12 1993-01-12 Dana Farber Cancer Institute Method of suppressing tumor formation in vivo
US5212073A (en) * 1989-05-12 1993-05-18 Genetics Institute, Inc. Process for producing human JE cytokine
ES2076378T5 (es) * 1989-09-25 1999-10-16 Genetics Inst Metodo para la inhibicion del desarrollo de celulas de tallo.
NZ237202A (en) * 1990-02-23 1994-01-26 Bristol Myers Squibb Co Composition containing beta-lactam antibiotic and cationic oligopeptide
CA2091266A1 (en) * 1990-09-14 1992-03-15 Patricia Tekamp-Olson Expression of macrophage inducible proteins (mips) in yeast cells
US5401651A (en) * 1991-10-16 1995-03-28 Walz; Alfred DNA encoding ENA-78, a neutrophil activating factor
US5306709A (en) * 1991-11-15 1994-04-26 The University Of Pennsylvania Suppression of megakaryocytopoiesis by macrophage inflammatory proteins
US5413778A (en) * 1992-10-05 1995-05-09 The Regents Of The University Of Michigan Labelled monocyte chemoattractant protein material and medical uses thereof
US5346686A (en) * 1992-10-05 1994-09-13 Mallinckrodt Medical, Inc. Labelled interleukin-8 and medical uses thereof
US5474983A (en) * 1993-03-15 1995-12-12 The Research Foundation Of State University Of New York Method of inhibiting pro-inflammatory mediator release from basophils and mast cells
US5346685A (en) * 1993-04-23 1994-09-13 Mobil Oil Corp. Synthetic porous crystalline MCM-51, its synthesis and use
JPH0789866A (ja) * 1993-09-21 1995-04-04 Nippon Kayaku Co Ltd 感染防御剤
ATE262914T1 (de) * 1993-12-22 2004-04-15 Human Genome Sciences Inc Entzündungsproteine aus makrophagen mip-3, mip-4 und mip-1gamma
WO1995031468A1 (en) * 1994-05-16 1995-11-23 Human Genome Sciences, Inc. Macrophage migration inhibitory factor-3
JPH10505493A (ja) * 1994-08-23 1998-06-02 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド ヒトケモカインベータ−9
WO1996005856A1 (en) * 1994-08-23 1996-02-29 Human Genome Sciences, Inc. Human chemokine polypeptides
WO1996009062A1 (en) * 1994-09-23 1996-03-28 University Of Nebraska Board Of Regents Polypeptide agonists and antagonists of human interleukin-8
US5602008A (en) * 1994-11-29 1997-02-11 Incyte Pharmaceuticals, Inc. DNA encoding a liver expressed chemokine
EP0833914A4 (en) * 1995-06-05 2003-05-28 Human Genome Sciences Inc HUMAN CHEMOKINE BETA-11 AND ALPHA-1
WO1996039520A1 (en) * 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Human chemokine beta-12
MX9708528A (es) * 1995-06-06 1998-02-28 Human Genome Sciences Inc Quimiosina bata-13 humana.
ZA968896B (en) * 1995-10-24 1997-04-24 Smithkline Beecham Corp Method of mobilizing hematopoietic stem cells
CA2235360A1 (en) * 1995-10-24 1997-05-01 Smithkline Beecham Corporation Novel chemokine for mobilizing stem cells
WO1997019173A1 (en) * 1995-11-21 1997-05-29 Smithkline Beecham Corporation Method of treating sepsis
EP0885293B1 (en) * 1996-02-23 2006-06-07 Human Genome Sciences, Inc. Human chemokine polypeptides
US6509313B1 (en) * 1996-02-28 2003-01-21 Cornell Research Foundation, Inc. Stimulation of immune response with low doses of cytokines
EP0904398A4 (en) 1996-03-18 2004-12-01 Human Genome Sciences Inc CHEMOKINE ALPHA 3
EP0889961A2 (en) * 1996-03-27 1999-01-13 Icos Corporation Monocyte chemotactic protein-5 materials and methods
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10
GB9617923D0 (en) * 1996-08-28 1996-10-09 Smithkline Beecham Plc Novel receptor
AU4243097A (en) * 1996-09-10 1998-04-02 Schering Corporation Mammalian chemokines, related reagents
WO1998014573A1 (en) * 1996-09-30 1998-04-09 The General Hospital Corporation Mcp-4 and mcp-5: novel chemokines

Also Published As

Publication number Publication date
DE69721120T2 (de) 2003-12-04
US6406688B1 (en) 2002-06-18
DE69721120D1 (de) 2003-05-28
EP0807439A2 (en) 1997-11-19
US20020146390A1 (en) 2002-10-10
US20020155094A1 (en) 2002-10-24
US6290948B1 (en) 2001-09-18
JP2001122801A (ja) 2001-05-08
EP0807439B1 (en) 2003-04-23
JPH1053533A (ja) 1998-02-24
EP0807439A3 (en) 1998-03-11
US20020141972A1 (en) 2002-10-03

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