DK0814834T4 - Immunogener, der er blottet for toksicitet, afledt af et retroviralt regulatorprotein, antistoffer, der er rettet mod disse immunogener, fremgangsmåde til deres fremstilling og farmaceutiske sammensætninger, der indeholder dem - Google Patents

Immunogener, der er blottet for toksicitet, afledt af et retroviralt regulatorprotein, antistoffer, der er rettet mod disse immunogener, fremgangsmåde til deres fremstilling og farmaceutiske sammensætninger, der indeholder dem

Info

Publication number
DK0814834T4
DK0814834T4 DK96906795T DK96906795T DK0814834T4 DK 0814834 T4 DK0814834 T4 DK 0814834T4 DK 96906795 T DK96906795 T DK 96906795T DK 96906795 T DK96906795 T DK 96906795T DK 0814834 T4 DK0814834 T4 DK 0814834T4
Authority
DK
Denmark
Prior art keywords
immunogens
regulatory protein
pct
devoid
preparation
Prior art date
Application number
DK96906795T
Other languages
English (en)
Other versions
DK0814834T3 (da
Inventor
Daniel Zagury
Jean-Francois Zagury
Bernard Bizzini
Original Assignee
Neovacs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26231806&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0814834(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR9502708A external-priority patent/FR2731355B1/fr
Application filed by Neovacs filed Critical Neovacs
Publication of DK0814834T3 publication Critical patent/DK0814834T3/da
Application granted granted Critical
Publication of DK0814834T4 publication Critical patent/DK0814834T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/112—Retroviridae (F), e.g. leukemia viruses
    • C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1147—Regulatory proteins, e.g. trans-activator of transcription [TAT], rev or vacuolar protein targeting [VPT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/826—Viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK96906795T 1995-03-08 1996-03-07 Immunogener, der er blottet for toksicitet, afledt af et retroviralt regulatorprotein, antistoffer, der er rettet mod disse immunogener, fremgangsmåde til deres fremstilling og farmaceutiske sammensætninger, der indeholder dem DK0814834T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9502708A FR2731355B1 (fr) 1995-03-08 1995-03-08 Nouveaux immunogenes, nouveaux anticorps, procede de preparation et compositions pharmaceutiques les renfermant
PCT/FR1996/000357 WO1996027389A1 (fr) 1995-03-08 1996-03-07 Immunogenes denues de toxicite derivant d'une proteine de regulation retrovirale, anticorps, procede de preparation et compositions pharmaceutiques les renfermant

Publications (2)

Publication Number Publication Date
DK0814834T3 DK0814834T3 (da) 2000-11-13
DK0814834T4 true DK0814834T4 (da) 2009-07-20

Family

ID=26231806

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96906795T DK0814834T4 (da) 1995-03-08 1996-03-07 Immunogener, der er blottet for toksicitet, afledt af et retroviralt regulatorprotein, antistoffer, der er rettet mod disse immunogener, fremgangsmåde til deres fremstilling og farmaceutiske sammensætninger, der indeholder dem

Country Status (12)

Country Link
US (1) US6132721A (da)
EP (1) EP0814834B2 (da)
JP (1) JPH11501310A (da)
AT (1) ATE196255T1 (da)
AU (1) AU710626B2 (da)
BR (1) BR9607659A (da)
CA (1) CA2215483C (da)
DE (1) DE69610295T3 (da)
DK (1) DK0814834T4 (da)
GR (1) GR3034970T3 (da)
PL (1) PL322143A1 (da)
WO (1) WO1996027389A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9720585D0 (en) * 1997-09-26 1997-11-26 Smithkline Beecham Biolog Vaccine
FR2773156B1 (fr) * 1997-12-26 2000-03-31 Biovacs Inc Nouveaux immunogenes anti-retroviraux (toxoides), nouveaux procedes de preparation et application a la prevention et au traitement du sida
FR2781158B1 (fr) * 1998-07-15 2002-12-13 Vacs Internat Nouvelles proteines modifiees immunogenes non immunosuppressives, leur procede de preparation et leurs applications
FR2792206B1 (fr) * 1999-04-13 2006-08-04 Centre Nat Rech Scient Vaccin anti-vih-1 comprenant tout ou partie de la proteine tat de vih-1
US20050226890A1 (en) * 1999-08-12 2005-10-13 Cohen David I Tat-based vaccine compositions and methods of making and using same
AU785258B2 (en) * 1999-08-12 2006-12-07 Nanirx, Inc. Non-immunosuppressant HIV tat
US8323928B2 (en) 1999-08-12 2012-12-04 Pin Pharma, Inc. Vaccines and immunotherapeutics derived from the human immunodeficiency virus (HIV) transactivator of transcription protein for the treatment and prevention of HIV disease
FR2802426B1 (fr) 1999-12-15 2004-04-02 Neovacs Utilisation de proteines immunogenes immunosuppressives et/ou angiogeniques rendues inactives, pour la production d'iga secretoires
JP2003529559A (ja) * 2000-01-31 2003-10-07 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 新規用途
US20080044435A1 (en) * 2004-03-16 2008-02-21 Cohen David I Tat-Based Tolerogen Compositions and Methods of Making and Using Same
NO314587B1 (no) * 2000-09-04 2003-04-14 Bionor Immuno As HIV regulatoriske- og hjelpepeptider, antigener, vaksinepreparater, immunoassay testsett og en metode for påvisning av antistoffer fremkaltav HIV
FR2828404B1 (fr) * 2001-08-10 2005-07-15 Neovacs Superimmunogene composite a usage vaccinal bifonctionnel pour le traitement des maladies associees a un desordre tissulaire stromal
CA2469487A1 (en) * 2001-12-11 2003-07-03 Aventis Pasteur Mutated hiv tat
WO2003073984A2 (en) * 2002-03-01 2003-09-12 University Of Kentucky Research Foundation Tat as an immunogen
FR2844514B1 (fr) * 2002-09-16 2007-10-19 Neovacs Produit immunogene stable comprenant des heterocomplexes antigeniques, compositions les contenant et procede de preparation
US20050208482A1 (en) * 2004-03-16 2005-09-22 Cohen David I Tat-based immunomodulatory compositions and methods for their discovery and use
JP5692933B2 (ja) 2009-03-23 2015-04-01 ナニアールエックス セラピューティックス インコーポレイテッド 免疫刺激ＨＩＶＴａｔ誘導体ポリペプチドによる腫瘍治療
WO2015051245A1 (en) 2013-10-04 2015-04-09 Pin Pharma, Inc. Immunostimulatory hiv tat derivative polypeptides for use in cancer treatment

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2227861B1 (da) † 1973-05-04 1976-07-02 Anvar
EP0330359A3 (en) * 1988-02-25 1991-06-05 Bio-Rad Laboratories, Inc. Composition useful in the diagnosis and treating of hiv-1 infection
WO1989012461A1 (en) * 1988-06-16 1989-12-28 St. Louis University Antagonists of viral transactivating proteins
EP0522081A4 (en) * 1990-03-30 1993-06-16 Smithkline Beecham Corporation Inhibition of disease associated with immunodeficiency virus infection
WO1991018454A1 (en) * 1990-05-18 1991-11-28 Centre National De La Recherche Scientifique Compositions capable of blocking cytotoxicity of viral regulatory proteins and neurotoxic symptoms associated with retroviral infection
AU1449792A (en) * 1991-02-14 1992-09-15 La Jolla Cancer Research Foundation A novel integrin specificity for the hiv tat protein
CA2134080C (en) * 1992-04-24 2004-07-13 Toby C. Rodman Natural humain igm antibodies
WO1993025235A1 (en) * 1992-06-09 1993-12-23 President And Fellows Of Harvard College Aids therapeutics based on hiv-2 vpx peptides
WO1994015634A1 (en) * 1992-12-30 1994-07-21 Matthias Rath Tat and rev oligopeptides in hiv treatment
FR2700169B1 (fr) * 1993-01-04 1995-03-24 Transgene Sa Nouveaux variants trans-dominants TAT du virus de l'immunodéficience humaine.
AU7263994A (en) * 1993-08-06 1995-02-28 Kai Juhani Ernst Krohn Novel mutated human and simian immunodeficiency viruses and vaccines containing said viruses

Also Published As

Publication number Publication date
EP0814834A1 (fr) 1998-01-07
DK0814834T3 (da) 2000-11-13
AU5007196A (en) 1996-09-23
DE69610295T2 (de) 2001-02-22
GR3034970T3 (en) 2001-02-28
JPH11501310A (ja) 1999-02-02
EP0814834B1 (fr) 2000-09-13
DE69610295D1 (de) 2000-10-19
CA2215483C (fr) 2012-01-03
WO1996027389A1 (fr) 1996-09-12
DE69610295T3 (de) 2009-10-08
ATE196255T1 (de) 2000-09-15
CA2215483A1 (fr) 1996-09-12
BR9607659A (pt) 1998-12-15
AU710626B2 (en) 1999-09-23
EP0814834B2 (fr) 2009-03-18
PL322143A1 (en) 1998-01-05
US6132721A (en) 2000-10-17

Similar Documents

Publication Publication Date Title
DK0814834T3 (da) Immunogener, der er blottet for toksicitet, afledt af et retroviralt regulatorprotein, antistoffer, der er rettet mod disse
DK0813525T3 (da) Benzamidinderivater, deres fremstilling og anvendelse som antikoagulanter
SE9300140D0 (sv) Solid substrate
DE60009511D1 (de) Nematizide trifluorbutene
EA200001030A1 (ru) Получение капсул и таблеток быстрорастворяющегося эфавиренза с использованием супердезинтеграторов
DE59504589D1 (de) Wäschenachbehandlungsmittel
DK0790824T3 (da) 2,2-dichloralkancarboxylsyrer, fremgangsmåde til fremstilling deraf, lægemidler indeholdende disse og anvendelse af disse lægemidler til behandling af insulinresistens
DE69830751D1 (de) Polyaromatische Verbindungen zur Behandlung von Herpes-Infektionen
PT1268498E (pt) Fosfonatos cardioprotectores
FI953369A7 (fi) Farmaseuttiset koostumukset syöpäsairauksien estämiseksi ja hoitamiseksi sekä menetelmä niiden valmistamiseksi
DK0517986T3 (da) Transformerede erythrocytter, fremgangsmåde til fremstilling af samme og deres anvendelse i farmaceutiske præparater
DE69836678D1 (de) Chinolin- und chinazolinderivate als antagonisten des corticotropin freisetzenden faktors (crf)
DK508388A (da) Sammensaetninger indeholdende biosyntetiske pesticidprodukter, fremgangsmaade til deres fremstilling og deres anvendelse
ATE179164T1 (de) Hiv-proteaseinhibitoren
PT94957A (pt) Processo para preparacao de composicoes farmaceuticas para tratamento da hipertrofia e hiperplasia cardiais e vasculares compreendendo um inibidor do enzima de conversao da angiotensina
ATE945T1 (de) Antikoagulierungsmittel, verfahren zu dessen herstellung und es enthaltende pharmazeutische zusammensetzungen.
FR2763592B1 (fr) Nouveaux derives glycosyles des ginkgolides, leur application en tant que medicaments et compositions pharmaceutiques les contenant
DK0550532T3 (da) Dextrinsulfater som anti-HIV-1-midler og præparat indeholdende disse
EP0594795A4 (en) MICHELLAMINES USEFUL AS ANTIVIRAL AGENTS, COMPOSITION AND METHOD OF TREATMENT.
IS4468A (is) Vatnslausn til inndælingar sem er stöðug við geymslu og inniheldur þrombín-hemil
DE69715013D1 (de) S-alkylisothiouronium-derivate enthaltende pharmazeutische zusammensetzungen
BR9610175A (pt) Composto processo de preparação do composto composição farmacêutica e utilização do composto
BG90414A (bg) 2-азабицикло (2,2,1)-хепт-5- ен-2-оцетна киселина и нейни производни, метод за получаване и приложението им
ES2150107T3 (es) Inmunogenos no toxicos que proceden de una proteina de regulacion retroviral, anticuerpos dirigidos contra estos inmunogenos, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
PT99280A (pt) Processo de preparacao de derivados do indolo e de composicoes farmaceuticas